TheraRadar

Ironwood

Pre-Approval PRO BETA
🔴

Stale Activity

No new clinical trials started in 2+ years. Activity may be declining or company may be focusing on existing programs. Last trial started: 3/28/2023

20
Total Trials
7
Phase 3
8
Phase 2
0
Recruiting
178
Score

Pipeline by Phase

Phase 3
7
Phase 2
8
Phase 1
3

Therapeutic Focus

Healthy Volunteers Irritable Bowel Syndrome With Constipation Irritable Bowel Syndrome Characterized by Constipation Gastroesophageal Reflux Disease (GERD) Chronic Constipation

Clinical Trials (20)

NCT03561090 Phase 3 TERMINATED

A Trial of IW-3718 for 8 Weeks in Patients With Persistent Gastroesophageal Reflux Disease (GERD) Receiving Proton Pump Inhibitors (PPIs)

Started: 6/20/2018

NCT03561883 Phase 3 COMPLETED

Trial of IW-3718 for 8 Weeks in Patients With Persistent Gastroesophageal Reflux Disease (GERD) Receiving Proton Pump Inhibitors (PPIs)

Started: 9/6/2018

NCT03573908 Phase 3 COMPLETED

A Trial of Linaclotide 290 μg in Patients With Irritable Bowel Syndrome With Constipation (IBS-C)

Started: 6/20/2018

NCT00730171 Phase 3 COMPLETED

An Open-label, Long-term Safety Study of Linaclotide in Patients With Chronic Constipation or Irritable Bowel Syndrome With Constipation

Started: 9/1/2008

NCT02291679 Phase 3 COMPLETED

Trial of Linaclotide in Patients With Chronic Idiopathic Constipation

Started: 10/1/2014

NCT00938717 Phase 3 COMPLETED

Trial of Linaclotide in Patients With Irritable Bowel Syndrome With Constipation (IBS-C)

Started: 7/1/2009

NCT00730015 Phase 3 COMPLETED

Trial of Linaclotide in Patients With Chronic Constipation

Started: 8/1/2008

NCT05740007 Phase 2 TERMINATED

A Phase 2 Study of IW-3300 for the Treatment of Bladder Pain in Subjects With Interstitial Cystitis/Bladder Pain Syndrome

Started: 3/28/2023

NCT01107236 Phase 2 COMPLETED

Study to Evaluate Efficacy and Safety of IW-6118 in Patients Undergoing Third Molar Extraction

Started: 6/1/2010

NCT03931785 Phase 2 COMPLETED

A Study of MD-7246 to Treat Abdominal Pain in Patients With Diarrhea-predominant Irritable Bowel Syndrome

Started: 5/1/2019

NCT02559206 Phase 2 COMPLETED

Trial of Linaclotide in Patients With Irritable Bowel Syndrome With Constipation (IBS-C)

Started: 10/22/2015

NCT02637557 Phase 2 COMPLETED

A Trial of IW-3718 for 8 Weeks in Patients With Symptomatic Gastroesophageal Reflux Disease (GERD)

Started: 3/1/2016

NCT02289846 Phase 2 COMPLETED

Trial of IW-9179 in Patients With Diabetic Gastroparesis (DGP)

Started: 10/1/2014

NCT02030925 Phase 2 COMPLETED

Ph2a Study to Evaluate IW-3718 in Patients With Gastroesophageal Reflux Not Completely Responsive to Proton Pump Inhibitors

Started: 2/1/2014

NCT01712412 Phase 2 TERMINATED

Phase 2a Study of IW-9179 to Treat Functional Dyspepsia

Started: 10/1/2012

NCT05362695 Phase 1 COMPLETED

A Study of Multiple-ascending Doses of IW-3300 in Healthy Subjects

Started: 5/17/2022

NCT05188261 Phase 1 COMPLETED

A Study of Single Ascending Doses of IW-3300 in Healthy Volunteers

Started: 1/18/2022

NCT03856970 Phase 1 COMPLETED

Study to Evaluate the Effect of IW-3718 on the Pharmacokinetics of Oral Contraceptive, Levothyroxine, Glyburide, and Digoxin in Healthy Adult Volunteers

Started: 3/11/2019

NCT02837783 Phase 4 TERMINATED

A Study of the Effect of Linaclotide on Abdominal Girth in Participants With Irritable Bowel Syndrome With Constipation (IBS-C)

Started: 12/21/2016

NCT03226899 Phase 4 TERMINATED

A Phase 4 Safety and Efficacy Study to Evaluate Lesinurad 200 mg in Participants With Gout and Renal Impairment

Started: 7/19/2017

Drug Candidates

IW-3300 rectal foam Placebo IW-3300 IW-6118 Matching Placebo Naproxen Sodium Linaclotide Lesinurad XOI colchicine
Activity Status: Stale
Last Trial Started: 3/28/2023
Last Trial Ended: 2/6/2025
Trials (12 months): 0
Completed Trials: 15
Data sourced from ClinicalTrials.gov. This company has no FDA-approved drugs.