TheraRadar
Clinical-Stage Companies / Lykos

Lykos

Pre-Approval PRO BETA
22
Total Trials
3
Phase 3
14
Phase 2
0
Recruiting
185
Score

Pipeline by Phase

Phase 3
3
Phase 2
14
Phase 1
6

Therapeutic Focus

Posttraumatic Stress Disorder PTSD Psychological Effects of Study Drug Pharmacokinetics Posttraumatic Stress Disorder (PTSD)

Clinical Trials (22)

NCT03537014 Phase 3 COMPLETED

A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD (MAPP1)

Started: 11/21/2018

NCT04714359 Phase 3 COMPLETED

A Multi-Site Open-Label Extension Study of MDMA-Assisted Psychotherapy for PTSD

Started: 3/8/2021

NCT04077437 Phase 3 COMPLETED

A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD (MAPP2)

Started: 9/2/2020

NCT04784143 Phase 2 TERMINATED

Study Comparing Two Versus Three Active MDMA-assisted Sessions in U.S. Military Veterans With Chronic PTSD

Started: 11/8/2021

NCT03485287 Phase 2 COMPLETED

Study of Safety and Effects of MDMA-assisted Psychotherapy for Treatment of PTSD (Canada)

Started: 3/13/2018

NCT01689740 Phase 2 COMPLETED

Randomized, Double-blind, Placebo-Controlled Pilot Study of MDMA-assisted Therapy for PTSD

Started: 1/17/2013

NCT03282123 Phase 2 COMPLETED

Open Label Multi-Site Study of Safety and Effects of MDMA-assisted Therapy for Treatment of PTSD

Started: 11/16/2017

NCT01958593 Phase 2 TERMINATED

Randomized, Double-blind, Controlled of MDMA-assisted Psychotherapy in 12 Subjects With PTSD

Started: 10/14/2014

NCT02008396 Phase 2 COMPLETED

Phase 2 Pilot Safety Study of MDMA-assisted Therapy for Social Anxiety in Autistic Adults

Started: 4/11/2014

NCT02427568 Phase 2 COMPLETED

MDMA-Assisted Psychotherapy for Anxiety Associated With a Life-Threatening Illness

Started: 5/14/2015

NCT01211405 Phase 2 COMPLETED

Study Comparing Three Doses of MDMA Along With Therapy in Veterans With Posttraumatic Stress Disorder

Started: 11/10/2010

NCT01793610 Phase 2 COMPLETED

Dose-Response Study of MDMA-assisted Psychotherapy in People With PTSD

Started: 5/13/2013

NCT04968938 Phase 2 WITHDRAWN

Study of Safety and Effects of MDMA-assisted Therapy for Treatment of PTSD

Started: 8/1/2022

NCT04454684 Phase 2 WITHDRAWN

A Multi-Site Study of MDMA-Assisted Psychotherapy for Eating Disorders

Started: 2/1/2026

NCT05173831 Phase 2 WITHDRAWN

Study of Feasibility and Safety of MDMA-Assisted Group Therapy for the Treatment of PTSD in Veterans

Started: 9/1/2023

NCT01458327 Phase 2 COMPLETED

Additional MDMA-assisted Therapy for People Who Relapsed After MDMA-assisted Therapy Trial

Started: 12/15/2010

NCT02876172 Phase 1 COMPLETED

MDMA-Assisted Cognitive-Behavioral Conjoint Therapy (CBCT) in Dyads in Which 1 Member Has Chronic PTSD

Started: 7/3/2016

NCT03181763 Phase 1 COMPLETED

Evaluation of MDMA on Startle Response

Started: 3/14/2017

NCT01404754 Phase 1 COMPLETED

Psychological Effects of Methylenedioxymethamphetamine (MDMA) When Administered to Healthy Volunteers

Started: 4/9/2011

NCT04073433 Phase 1 WITHDRAWN

Psychological Effects of Methylenedioxymethamphetamine (MDMA) When Administered to Healthy Volunteers (MT-2)

Started: 12/1/2024

NCT05147402 Phase 1 COMPLETED

Food Effects on Bioavailability of MDMA in Healthy Volunteers

Started: 7/28/2022

NCT03606538 Phase 1 NOT YET RECRUITING

MDMA in Subjects With Moderate Hepatic Impairment and Subjects With Normal Hepatic Function

Started: 3/29/2026

Drug Candidates

Midomafetamine Midomafetamine HCl Active Placebo Dose MDMA-assisted therapy (25 mg) Full Dose MDMA-assisted therapy (125 mg) Open-Label Full Dose MDMA-assisted therapy (125 mg) midomafetamine HCl Placebo Low dose MDMA-assisted therapy Medium dose MDMA-assisted therapy Full dose MDMA-assisted therapy
Activity Status: Active
Last Trial Started: 3/29/2026
Last Trial Ended: 6/27/2024
Trials (12 months): 2
Completed Trials: 15
Data sourced from ClinicalTrials.gov. This company has no FDA-approved drugs.