TheraRadar

Marinus

Pre-Approval PRO BETA
🔴

Stale Activity

No new clinical trials started in 2+ years. Activity may be declining or company may be focusing on existing programs. Last trial started: 3/1/2024

17
Total Trials
7
Phase 3
10
Phase 2
0
Recruiting
185
Score

Pipeline by Phase

Phase 3
7
Phase 2
10
Phase 1

Therapeutic Focus

Status Epilepticus Tuberous Sclerosis Complex Depressive Disorder Depression Depression, Postpartum

Clinical Trials (17)

NCT05604170 Phase 3 TERMINATED

Open-label Study of Adjunctive GNX Treatment in Children and Adults With TSC-related Epilepsy

Started: 5/16/2022

NCT05323734 Phase 3 COMPLETED

Adjunctive GNX Treatment Compared With Placebo in Children and Adults With TSC-related Epilepsy

Started: 4/1/2022

NCT04391569 Phase 3 COMPLETED

Randomized Therapy In Status Epilepticus

Started: 12/9/2020

NCT05814523 Phase 3 WITHDRAWN

To Evaluate the Efficacy, Safety, and Tolerability of Intravenous Ganaxolone Added to Standard of Care in Refractory Status Epilepticus (RSE)

Started: 3/1/2024

NCT02519439 Phase 3 TERMINATED

A Two-year Open-label Extension Study of Ganaxolone in Patients With Drug-resistant Partial-onset Seizures

Started: 2/1/2015

NCT03572933 Phase 3 COMPLETED

Study of Adjunctive Ganaxolone Treatment in Children and Young Adults With CDKL5 Deficiency Disorder

Started: 6/30/2018

NCT01963208 Phase 3 COMPLETED

Phase 3 Study of Adjunctive Ganaxolone in Adults With Drug-resistant Partial Onset Seizures and Open-label Extension

Started: 10/1/2013

NCT05757544 Phase 2 WITHDRAWN

Safety and Efficacy Study of IV Ganaxolone as Adjuvant Therapy for Established Status Epilepticus (ESE)

Started: 4/1/2023

NCT03460756 Phase 2 COMPLETED

A Clinical Trial of Oral Ganaxolone in Women With Postpartum Depression

Started: 12/28/2017

NCT03228394 Phase 2 COMPLETED

A Clinical Trial of Intravenous (IV) Ganaxolone in Women With Postpartum Depression

Started: 6/27/2017

NCT03865732 Phase 2 COMPLETED

Study of Adjunctive Ganaxolone Treatment in Female Children With Protocadherin 19 (PCDH19)-Related Epilepsy (Violet Study)

Started: 5/17/2019

NCT01725152 Phase 2 COMPLETED

Ganaxolone Treatment in Children With Fragile X Syndrome

Started: 11/1/2012

NCT04285346 Phase 2 COMPLETED

Adjunctive Ganaxolone Treatment (Part A) in TSC Followed by Long-term Treatment (Part B)

Started: 4/8/2020

NCT02358538 Phase 2 COMPLETED

Open-Label PoC Trial of Ganaxolone in Children With PCDH19 Female Pediatric Epilepsy and Other Rare Genetic Epilepsies

Started: 11/6/2015

NCT03350035 Phase 2 COMPLETED

Intravenous Ganaxolone as Adjunctive Therapy to Treat Subjects With Status Epilepticus

Started: 2/19/2018

NCT01339689 Phase 2 COMPLETED

Ganaxolone in Posttraumatic Stress Disorder (PTSD)

Started: 4/1/2011

NCT01002820 Phase 2 COMPLETED

A Treatment Use Protocol for Subjects Continuing on From the Open-label Extension 0601

Started: 10/1/2009

Drug Candidates

Ganaxolone Placebo Standard of care IV Ganaxolone IV Placebo ganaxolone IV Ganaxolone active IV Placebo, non-active
Activity Status: Stale
Last Trial Started: 3/1/2024
Last Trial Ended: 4/2/2025
Trials (12 months): 0
Completed Trials: 13
Data sourced from ClinicalTrials.gov. This company has no FDA-approved drugs.