TheraRadar

Mesoblast

Pre-Approval PRO BETA

Also known as: Mesoblast, Inc., Mesoblast, Ltd.

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Slowing Activity

No new clinical trials started in 1-2 years. Monitor for changes in pipeline strategy. Last trial started: 7/3/2024

22
Total Trials
8
Phase 3
14
Phase 2
1
Recruiting
247
Score

Pipeline by Phase

Phase 3
8
Phase 2
14
Phase 1
5

Therapeutic Focus

Degenerative Disc Disease Degenerative Spondylolisthesis Spinal Stenosis Cervical Degenerative Disc Disease Type 2 Diabetes

Clinical Trials (22)

NCT06325566 Phase 3 RECRUITING

Efficacy and Safety of Rexlemestrocel-L Combined With HA* in Participants With Moderate to Severe Chronic Low Back Pain

Started: 7/3/2024

NCT02032004 Phase 3 COMPLETED

Efficacy and Safety of Allogeneic Mesenchymal Precursor Cells (Rexlemestrocel-L) for the Treatment of Heart Failure

Started: 3/3/2014

NCT01233960 Phase 3 COMPLETED

Evaluation of PROCHYMAL® for Treatment-refractory Moderate-to-severe Crohn's Disease

Started: 11/29/2010

NCT02336230 Phase 3 COMPLETED

A Prospective Study of Remestemcel-L, Ex-vivo Cultured Adult Human Mesenchymal Stromal Cells, for the Treatment of Pediatric Participants Who Have Failed to Respond to Steroid Treatment for Acute Graft-Versus-Host Disease (aGVHD)

Started: 6/4/2015

NCT02652130 Phase 3 COMPLETED

Safety Follow-up of Treatment With Remestemcel-L in Pediatric Participants Who Have Failed to Respond to Steroid Treatment for Acute GVHD

Started: 10/28/2015

NCT00562497 Phase 3 COMPLETED

Efficacy and Safety of Prochymal® Infusion in Combination With Corticosteroids for the Treatment of Newly Diagnosed Acute Graft Versus Host Disease (GVHD)

Started: 1/31/2008

NCT02412735 Phase 3 COMPLETED

Placebo-controlled Study to Evaluate Rexlemestrocel-L Alone or Combined With Hyaluronic Acid in Participants With Chronic Low Back Pain

Started: 3/6/2015

NCT01854567 Phase 3 COMPLETED

P3 Study of Umbilical Cord Blood Cells Expanded With MPCs for Transplantation in Patients With Hematologic Malignancies

Started: 8/1/2013

NCT00877903 Phase 2 COMPLETED

Prochymal® (Human Adult Stem Cells) Intravenous Infusion Following Acute Myocardial Infarction (AMI)

Started: 3/30/2009

NCT00683722 Phase 2 COMPLETED

PROCHYMAL™ (Human Adult Stem Cells) for the Treatment of Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Started: 3/20/2008

NCT00690066 Phase 2 COMPLETED

PROCHYMAL® (Human Adult Stem Cells) for the Treatment of Recently Diagnosed Type 1 Diabetes Mellitus (T1DM)

Started: 6/11/2008

NCT01781390 Phase 2 COMPLETED

Safety Study of Allogeneic Mesenchymal Precursor Cell Infusion in Myocardial Infarction

Started: 3/11/2013

NCT00996073 Phase 2 COMPLETED

Safety and Preliminary Efficacy Study of NeoFuse in Subjects Requiring Lumbar Interbody Fusion

Started: 9/1/2009

NCT01851070 Phase 2 COMPLETED

A Multi-center Study a Single IV Infusion of Allogeneic MPCs in Patients With Rheumatoid Arthritis and Incomplete Response to at Least One TNFα Inhibitor

Started: 7/1/2013

NCT01290367 Phase 2 COMPLETED

Safety and Preliminary Efficacy Study of Mesenchymal Precursor Cells (MPCs) in Subjects With Lumbar Back Pain

Started: 8/1/2011

NCT00721045 Phase 2 COMPLETED

A Phase II Dose-escalation Study to Assess the Feasibility and Safety of Transendocardial Delivery of Three Different Doses of Allogeneic Mesenchymal Precursor Cells (MPCs)in Subjects With Heart Failure

Started: 8/1/2008

NCT01097486 Phase 2 COMPLETED

Safety and Preliminary Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy

Started: 6/1/2010

NCT01106417 Phase 1 COMPLETED

Safety and Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy and Fusion

Started: 6/1/2010

NCT00810212 Phase 1 WITHDRAWN

Safety and Efficacy Study of NeoFuse in Subjects Requiring Posterolateral Lumbar Fusion

Started: 11/1/2008

NCT01576328 Phase 1 COMPLETED

Safety Study of Mesenchymal Precursor Cells in Type 2 Diabetes

Started: 4/1/2012

NCT01088191 Phase 1 COMPLETED

Safety and Efficacy Study of MSB-CAR001 in Subjects 6 Weeks Post an Anterior Cruciate Ligament Reconstruction

Started: 3/1/2009

NCT01843387 Phase 1 COMPLETED

Safety and Efficacy of Mesenchymal Precursor Cells in Diabetic Nephropathy

Started: 7/1/2013

Drug Candidates

Rexlemestrocel-L Prochymal® Placebo Prochymal™ PROCHYMAL® Mesenchymal Precursor Cells (MPC) 12.5 M Mesenchymal Precursor Cells (MPC) 25 M remestemcel-L Remestemcel-L Rexlemestrocel-L + HA mixture
Activity Status: Slowing
Last Trial Started: 7/3/2024
Last Trial Ended: 6/15/2021
Trials (12 months): 0
Completed Trials: 20
Data sourced from ClinicalTrials.gov. This company has no FDA-approved drugs.