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Clinical-Stage Companies / Shanghai JMT-Bio

Shanghai JMT-Bio

Pre-Approval PRO BETA
30
Total Trials
15
Phase 3
13
Phase 2
15
Recruiting
419
Score

Pipeline by Phase

Phase 3
15
Phase 2
13
Phase 1
10

Therapeutic Focus

Non-Small Cell Lung Cancer HER2-positive Gastric Cancer Local Advanced or Metastatic NSCLC Resectable HER2-positive Breast Cancer Small Cell Lung Cancer

Clinical Trials (30)

NCT07441460 Phase 3 RECRUITING

A Phase III Study of KN026 in Combination With HB1801 as Adjuvant Therapy for Resectable HER2-Positive Breast Cancer

Started: 3/6/2026

NCT05838066 Phase 3 RECRUITING

Efficacy and Safety of KN026 in Combination With HB1801 in the First-line Treatment of Subjects With HER2-positive Recurrent or Metastatic Breast Cancer.

Started: 7/23/2023

NCT06747338 Phase 3 RECRUITING

A Phase III Study of KN026 in Combination With HB1801 ± Carboplatin as Neoadjuvant Treatment for Early or Locally Advanced HER2-Positive Breast Cancer

Started: 12/16/2024

NCT06829459 Phase 3 RECRUITING

A Study to Evaluate the Efficacy and Safety of Glumetinib Combined With Osimertinib Mesylate Versus Platinum-based Doublet Chemotherapy in Non-Small Cell Lung Cancer Patients After Resistance to EGFR-TKIs

Started: 4/3/2025

NCT06846437 Phase 3 RECRUITING

JSKN003 Versus Trastuzumab Emtansine (T-DM1) for HER2-Positive, Advanced Breast Cancer

Started: 2/18/2025

NCT06735391 Phase 3 RECRUITING

A Clinical Study of JMT101 in Combination With Osimertinib Versus Osimertinib Alone as First-Line Treatment for Patients With Locally Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC) Harboring Epidermal Growth Factor Receptor (EGFR) Sensitive Mutations

Started: 10/23/2024

NCT07384377 Phase 3 NOT YET RECRUITING

JSKN003 Versus Physician Choiced Treatment in Patients With HER2-positive and Advanced Colorectal Cancer Who Had Failed to Respond to Oxaliplatin, 5-Fu, and Irinotecan

Started: 2/6/2026

NCT07134205 Phase 3 NOT YET RECRUITING

The Study of JMT101 Combined With Irinotecan as a ≥3rd-Line Treatment in Metastatic Colorectal Cancer

Started: 10/1/2025

NCT06380348 Phase 3 NOT YET RECRUITING

JMT101 in Combination With Osimertinib, Versus Cisplatin-pemetrexed in Participants With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Characterized by Epithermal Growth Factor Receptor (EGFR) Exon 20ins Mutations

Started: 4/26/2024

NCT06221072 Phase 3 NOT YET RECRUITING

A Study to Assess the Prevention of Bone-related Events in Patients With Bone Metastases From Malignant Solid Tumors Treated With JMT103 Compared to Zoledronic Acid

Started: 4/5/2024

NCT05813665 Phase 3 NOT YET RECRUITING

A Study to Evaluate the Efficacy and Safety of Narlumosbart (JMT103) in Patients With Giant Cell Tumor of Bone

Started: 4/1/2023

NCT05427383 Phase 2 RECRUITING

KN026 in Combination With Chemotherapy in HER2 Positive Gastric Cancer Subjects Who Have Failed First-line Therapy

Started: 4/7/2022

NCT07332533 Phase 2 NOT YET RECRUITING

A Study of KN026-based Combination Therapy in HER2-positive Gastric Cancer

Started: 12/30/2025

NCT07029139 Phase 2 NOT YET RECRUITING

A Study to Learn More About the Effects and Safety of JMT601 in Adults With Primary Membranous Nephropathy

Started: 6/30/2025

NCT06998771 Phase 2 NOT YET RECRUITING

JSKN003 Combined Treatment of HER2-positive Gastric Cancer

Started: 6/15/2025

NCT06908772 Phase 2 NOT YET RECRUITING

Glumetinib Combined With Osimertinib Treatment for Non-Small Cell Lung Cancer Patients

Started: 4/1/2025

NCT06892431 Phase 2 NOT YET RECRUITING

JMT101 Combined With Mitoxantrone Liposome for Nasopharyngeal Cancer

Started: 4/1/2025

NCT06391944 Phase 2 ACTIVE NOT RECRUITING

JMT101 Combined With Osimertinib in Patients With Stage Ⅲb-Ⅳ Non-small Cell Lung Cancer (NSCLC) Characterized by Epithermal Growth Factor Receptor (EGFR) Common Mutations

Started: 11/21/2021

NCT06319313 Phase 2 NOT YET RECRUITING

Efficacy and Safety of JMT101 Combined Wth Docetaxel / HB1801 in Patients With Squamous Cell Non-Small Cell Lung Cancer

Started: 5/1/2024

NCT07545044 Phase 2 NOT YET RECRUITING

A Study of JSKN003 Versus Trastuzumab in Combination With Pertuzumab and Docetaxel as First-Line Treatment for HER2-Positive Recurrent or Metastatic Breast Cancer

Started: 5/30/2026

NCT07419698 Phase 1 RECRUITING

Evaluate the Safety, Tolerability, PK, and PD of JMT206 Injection in Healthy Participants

Started: 1/26/2026

NCT06877650 Phase 1 RECRUITING

First-in-Human Investigation of JMT108 Injection in Participants With Advanced Malignant Tumors

Started: 4/11/2025

NCT07280832 Phase 1 RECRUITING

Phase I/II Clinical Study of JMT108 Injection for the Treatment of Advanced Malignant Melanoma

Started: 12/17/2025

NCT07140809 Phase 1 RECRUITING

a Phase 1b/2a Study of JMT202 Injection in Participants With Hypertriglyceridemia

Started: 9/9/2025

NCT07275073 Phase 1 RECRUITING

JMT106 Injection in the Treatment of Advanced Solid Tumors

Started: 9/25/2025

NCT06868849 Phase 1 RECRUITING

A Study of JMT203 in Patients With Cancer Cachexia

Started: 5/15/2024

NCT06725524 Phase 1 RECRUITING

A Study of JMT601 in Participants With Relapsed or Refractory CD20-positive B-cell Non-Hodgkin Lymphoma

Started: 10/12/2021

NCT07472647 Phase 1 NOT YET RECRUITING

SYS6090 Combination Therapy in Advanced Lung Cancer

Started: 2/28/2026

NCT06564467 Phase 1 ENROLLING BY INVITATION

A Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of JMT202

Started: 7/23/2024

NCT04630522 Phase 1 COMPLETED

Efficacy and Safety of JMT103 in Patients With Bone Metastases From Solid Tumors

Started: 10/31/2020

Drug Candidates

KN026 HB1801 Trastuzumab Pertuzumab Docetaxel Epirubicin Doxorubicin Cyclophosphamide Carboplatin SYS6090 + pemetrexed + platinum-based chemotherapy
Activity Status: Active
Last Trial Started: 5/30/2026
Last Trial Ended: 3/31/2023
Trials (12 months): 12
Completed Trials: 1
Data sourced from ClinicalTrials.gov. This company has no FDA-approved drugs.