TheraRadar
Clinical-Stage Companies / Wave Life Sciences

Wave Life Sciences

Pre-Approval PRO BETA
14
Total Trials
1
Phase 3
11
Phase 2
3
Recruiting
144
Score

Pipeline by Phase

Phase 3
1
Phase 2
11
Phase 1
12

Therapeutic Focus

Duchenne Muscular Dystrophy Huntington Disease ALS FTD Huntington's Disease

Clinical Trials (14)

NCT07209332 Phase 2 ENROLLING BY INVITATION

Open-Label Extension Study of WVE-N531 in Patients With Duchenne Muscular Dystrophy

Started: 12/28/2025

NCT03907072 Phase 2 TERMINATED

Efficacy and Safety Study of WVE-210201 (Suvodirsen) With Open-label Extension in Ambulatory Patients With Duchenne Muscular Dystrophy

Started: 9/4/2019

NCT06842186 Phase 1 RECRUITING

A Phase 1 Study of WVE-007 in Adults Living With Overweight or Obesity

Started: 1/31/2025

NCT04906460 Phase 1 RECRUITING

Open-label Study of WVE-N531 in Patients With Duchenne Muscular Dystrophy (FORWARD-53)

Started: 9/28/2021

NCT06405633 Phase 1 ACTIVE NOT RECRUITING

A Phase 1b/2a, Open-label Single Ascending Doses and Multiple Ascending Doses Study in Participants With Pi*ZZ AATD

Started: 7/19/2024

NCT06186492 Phase 1 COMPLETED

A Phase 1 Research Study to Evaluate Safety, Tolerability, and Pharmacokinetics of WVE-006 in Healthy Participants With Wild-type AAT Expression (RestorAATion-1)

Started: 11/14/2023

NCT05032196 Phase 1 COMPLETED

Study of WVE-003 in Patients With Huntington's Disease

Started: 9/6/2021

NCT04931862 Phase 1 TERMINATED

Study of WVE-004 in Patients With C9orf72-associated Amyotrophic Lateral Sclerosis (ALS) or Frontotemporal Dementia (FTD)

Started: 6/28/2021

NCT05683860 Phase 1 TERMINATED

Open-label Extension (OLE) Study of WVE-004 in Patients With C9orf72-associated Amyotrophic Lateral Sclerosis (ALS) and/or Frontotemporal Dementia (FTD)

Started: 12/14/2022

NCT03225846 Phase 1 TERMINATED

Safety and Tolerability of WVE-120102 in Patients With Huntington's Disease

Started: 7/17/2017

NCT03225833 Phase 1 TERMINATED

Safety and Tolerability of WVE-120101 in Patients With Huntington's Disease

Started: 7/17/2017

NCT04617860 Phase 1 TERMINATED

Open-label Extension Study to Evaluate the Safety and Tolerability of WVE-120102 in Patients With Huntington's Disease

Started: 9/24/2019

NCT04617847 Phase 1 TERMINATED

Open-label Extension Study to Evaluate the Safety and Tolerability of WVE-120101 in Patients With Huntington's Disease

Started: 4/13/2020

NCT03508947 Phase 1 COMPLETED

Safety and Tolerability of WVE-210201 in Patients With Duchenne Muscular Dystrophy

Started: 1/24/2018

Drug Candidates

WVE-006 WVE-N531 WVE-007 SAD: 30mg WVE-003 SAD: 60mg WVE-003 SAD: 90mg WVE-003 SAD: Pooled Placebo MD: 30mg WVE-003 MD: Placebo WVE-004
Activity Status: Active
Last Trial Started: 12/28/2025
Last Trial Ended: 2/13/2025
Trials (12 months): 1
Completed Trials: 3
Data sourced from ClinicalTrials.gov. This company has no FDA-approved drugs.