Xenon
Pre-Approval PRO BETAPipeline by Phase
Therapeutic Focus
Clinical Trials (23)
A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)
Started: 7/8/2025
A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression)
Started: 8/8/2025
A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)
Started: 5/9/2023
A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
Started: 2/14/2023
A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder
Started: 12/20/2024
An Open-label Study of XEN1101 in Epilepsy
Started: 4/25/2023
An Open-label Study of Azetukalner in Bipolar I or II Depression (X-CEED-OLE)
Started: 10/30/2025
A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures
Started: 11/18/2022
An Open-Label Study of Azetukalner in Major Depressive Disorder
Started: 3/18/2025
An Open-Label Extension of the Study XEN496 (Ezogabine) in Children With KCNQ2-DEE
Started: 8/17/2021
XEN496 (Ezogabine) in Children With KCNQ2 Developmental and Epileptic Encephalopathy
Started: 3/29/2021
A Study to Evaluate XEN1101 as Adjunctive Therapy in Focal Epilepsy
Started: 1/30/2019
A Study to Evaluate the Safety, Tolerability and Efficacy of XEN1101 in Major Depressive Disorder
Started: 5/19/2022
A Crossover Study to Evaluate the Safety, Tolerability and Efficacy of XPF-002 in Subjects With Postherpetic Neuralgia (PHN)
Started: 8/1/2010
Safety and Efficacy Study of XPF-001 to Treat Pain Following Wisdom Tooth Extraction
Started: 9/1/2009
Safety, Tolerability, and Pharmacokinetics (PK) of Single and Multiple Ascending Oral Doses of XEN1101.
Started: 11/13/2017
Single-dose Mass Balance Recovery and Metabolite Profile and Identification of 14C-XEN1101
Started: 7/14/2021
Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Oral Doses of XEN901
Started: 2/19/2018
A Safety, Tolerability, Efficacy and Exposure Study of XEN801 Topical Gel
Started: 9/17/2015
Safety, Tolerability, Pharmacokinetics and Effects on Transcranial Magnetic Stimulation of Oral Doses of XEN1101
Started: 2/13/2018
Phase 2a, Exploratory Study to Evaluate the Safety, Efficacy, Tolerability and Pharmacokinetics of XPF-002 in Patients With Primary/Inherited Erythromelalgia
Started: 12/1/2011
Study of XPF-001 in the Treatment of Pain From Primary/Inherited Erythromelalgia (IEM)
Started: 4/1/2010
Single and Multiple Ascending Dose Safety Study of XPF-001 in Healthy Volunteers
Started: 11/1/2008