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Anxiety

CNS 0 original drugs
0
Novel Drugs
3
Reformulations
94
Active Trials
0
Drug Targets

Phase 3 Readouts Pro

5 active Phase 3 trials with confidence-graded completion dates.

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Q2 2026
MM120 (LSD D-Tartrate)
Definium Therapeutics US, Inc.
Estimated · fresh NCT06741228
Q2 2026
Buagafuran capsules, 15mg/ capsule
Beijing Union Pharmaceutical Factory Ltd
Estimated · stale NCT06243640
Q2 2026
Buagafuran capsules, 15mg/ capsule
Beijing Union Pharmaceutical Factory Ltd
Estimated · stale NCT06243614
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Anchored on CT.gov primary completion date. Topline announcements typically precede this by 3–9 months. Confidence labels combine date type (ACTUAL/ESTIMATED) with last-update freshness.

Treatments by Mechanism

Top 5 mechanisms across 5 industry trials with a known mechanism of action.

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alpha 2 -delta site
1 trials 1 sponsor
Atypical Antipsychotic
1 trials 1 sponsor
GABA receptor
1 trials 1 sponsor
5-HT transporter
1 trials 1 sponsor
SERT
1 trials 1 sponsor

MoA derived from FDA pharmClassEpc when intervention matches an approved drug. Codenamed clinical-stage assets without an approved counterpart show "—" and aren't grouped here — they're still in the phase tables below.

Clinical Pipeline by Phase

77 industry-sponsored trials across 40 sponsors

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Novel Drugs by Company (New molecular entities)

No novel drugs found for this indication.

Reformulations (3 drugs) Click to expand

Reformulations are FDA-approved versions of existing molecules in new dosage forms (e.g., oral solution vs tablet, extended-release vs immediate-release). They require a new NDA but use an already-proven active ingredient.

Generic Drugs (11 ANDA approved) Click to expand

Related Indications

Other CNS indications

Drug Categories:

  • Novel Drugs: NDA Type 1/2 (new molecular entity) or original BLA
  • Reformulations: NDA Type 3/5 (new dosage form of existing molecule)
  • Biosimilars: BLA-approved biologics highly similar to reference products
  • Generics: ANDA-approved copies of small molecule drugs

View data sources and methodology