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Hidradenitis Suppurativa

11 original drugs
11
Novel Drugs
1
Reformulations
0
Active Trials
4
Drug Targets

Phase 3 Readouts Pro

10 active Phase 3 trials with confidence-graded completion dates.

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Q3 2026
Bimekizumab
UCB Biopharma SRL
Estimated · fresh NCT04901195
Q4 2026
Ruxolitinib Cream
Incyte Corporation
Estimated · fresh NCT06959225
Q4 2026
Ruxolitinib Cream
Incyte Corporation
Estimated · fresh NCT06958211
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Anchored on CT.gov primary completion date. Topline announcements typically precede this by 3–9 months. Confidence labels combine date type (ACTUAL/ESTIMATED) with last-update freshness.

Treatments by Mechanism

Top 5 mechanisms across 9 industry trials with a known mechanism of action.

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Interleukin-17A Antagonist
3 trials 1 active 1 sponsor
Janus Kinase Inhibitor
1 trials 1 active 1 sponsor
DPP1
1 trials 1 active 1 sponsor
TNF
3 trials 3 sponsors
Complement 5a Receptor Antagonist
1 trials 1 sponsor

MoA derived from FDA pharmClassEpc when intervention matches an approved drug. Codenamed clinical-stage assets without an approved counterpart show "—" and aren't grouped here — they're still in the phase tables below.

Clinical Pipeline by Phase

74 industry-sponsored trials across 36 sponsors

Precision Medicine Biomarkers

All biomarkers →

Biomarkers used for patient selection in Hidradenitis Suppurativa

Reformulations (1 drugs) Click to expand

Reformulations are FDA-approved versions of existing molecules in new dosage forms (e.g., oral solution vs tablet, extended-release vs immediate-release). They require a new NDA but use an already-proven active ingredient.

Drug Categories:

  • Novel Drugs: NDA Type 1/2 (new molecular entity) or original BLA
  • Reformulations: NDA Type 3/5 (new dosage form of existing molecule)
  • Biosimilars: BLA-approved biologics highly similar to reference products
  • Generics: ANDA-approved copies of small molecule drugs

View data sources and methodology