NCT04172532 RECRUITING Testing the Addition of a New Anti-cancer Drug, M3814 (Peposertib), to the Usual Radiotherapy in Patients With Locally Advanced Pancreatic Cancer
National Cancer Institute (NCI)
NCT05554367 ACTIVE NOT RECRUITING Palbociclib and Binimetinib in RAS-Mutant Cancers, A ComboMATCH Treatment Trial
National Cancer Institute (NCI)
NCT04548752 ACTIVE NOT RECRUITING Testing the Addition of Pembrolizumab, an Immunotherapy Cancer Drug to Olaparib Alone as Therapy for Patients With Pancreatic Cancer That Has Spread With Inherited BRCA Mutations
National Cancer Institute (NCI)
NCT04550494 RECRUITING Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations
National Cancer Institute (NCI)
NCT07578337 NOT YET RECRUITING A Clinical Study Evaluating a New Treatment Strategy for Patients With Advanced Pancreatic Cancer Who Have Not Received Prior Treatment for Advanced Disease.
Nelum Corp
NCT04858334 RECRUITING APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation
National Cancer Institute (NCI)
NCT01972919 ACTIVE NOT RECRUITING MR Guided Phase II Radiotherapy Dose Escalation in Unresectable Non-Metastatic Pancreatic Cancer
Medical College of Wisconsin
NCT07529808 NOT YET RECRUITING Phase 1/2 Study of BHB810 in Advanced Gastric and GEJ Adenocarcinoma
BigHat Biosciences, Inc.
NCT01174121 RECRUITING Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Cancer
National Cancer Institute (NCI)
NCT07575191 NOT YET RECRUITING Safety and Performance of a Novel Infusion Catheter System for Peri/Intratumoral Gemcitabine Delivery in Patients With Pancreatic Cancer
Smartwise Sweden AB
NCT05922930 RECRUITING Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells Delivered Intraperitoneally for the Management of Platinum Resistant Ovarian Cancer, Mesonephric-like Adenocarcinoma, and Pancreatic Cancer
M.D. Anderson Cancer Center
NCT04083599 ACTIVE NOT RECRUITING GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors
Genmab
NCT03523312 ACTIVE NOT RECRUITING Use of High-dose Radiation Therapy Plus Chemotherapy to Improve the Likelihood of Surgical Treatment in Patients With Locally Advanced Pancreatic Cancer
Memorial Sloan Kettering Cancer Center
NCT06239194 RECRUITING Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors
ModeX Therapeutics, An OPKO Health Company
NCT04789486 RECRUITING Nano-SMART: Nanoparticles With MR Guided SBRT in Centrally Located Lung Tumors and Pancreatic Cancer
Dana-Farber Cancer Institute
NCT06094140 ACTIVE NOT RECRUITING NEO-adjuvant Chemo-immunotherapy in Pancreatic Cancer
Australasian Gastro-Intestinal Trials Group
NCT03652428 RECRUITING Phase I Nab-Paclitaxel Plus Gemcitabine With Proton Therapy for Locally Advanced Pancreatic Cancer (LAPC)
University of Maryland, Baltimore
NCT07076212 RECRUITING Evaluating NALIRIFOX vs Modified Gemcitabine, Nab-Paclitaxel and Cisplatin in Patients With Locally Advanced and Metastatic Pancreatic Adenocarcinoma
Medical University of South Carolina
NCT06941857 RECRUITING NC410 and FOLFIRINOX in Combination With Nivolumab With or Without Ipilimumab in Patients With Untreated Metastatic Pancreatic Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT07026279 ACTIVE NOT RECRUITING A Study of Narmafotinib Given in Combination With Modified FOLFIRINOX in Patients With Metastatic Pancreatic Cancer
Amplia Therapeutics Limited
NCT04851119 RECRUITING Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors
Children's Oncology Group
NCT04233866 ACTIVE NOT RECRUITING Comparing Two Treatment Combinations, Gemcitabine and Nab-Paclitaxel With 5-Fluorouracil, Leucovorin, and Liposomal Irinotecan for Older Patients With Pancreatic Cancer That Has Spread
ECOG-ACRIN Cancer Research Group
NCT06503146 RECRUITING 18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection
National Cancer Institute (NCI)
NCT07565155 NOT YET RECRUITING Lorigerlimab (MGD019) in Patients With Pancreatic Adenocarcinoma and Homologous Recombination Deficiency
Peter Hosein, MD
NCT06015659 ACTIVE NOT RECRUITING ZN-c3 + Gemcitabine in Pancreatic Cancer
Brandon Huffman, MD
NCT07563738 RECRUITING A 2-part Phase 1/2 Open-label Trial on ODM-212
Orion Corporation, Orion Pharma
NCT04421820 RECRUITING BOLD-100 in Combination With FOLFOX for the Treatment of Advanced Solid Tumours
Bold Therapeutics, Inc.
NCT05933265 ACTIVE NOT RECRUITING Study of LP-184 in Patients With Advanced Solid Tumors
Lantern Pharma Inc.
NCT07561463 NOT YET RECRUITING Sacituzumab Tirumotecan for Pancreatic Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT02498613 ACTIVE NOT RECRUITING A Phase 2 Study of Cediranib in Combination With Olaparib in Advanced Solid Tumors
National Cancer Institute (NCI)
NCT07157033 RECRUITING A Phase 1 Study to Evaluate Safety and Efficacy of XER-001 (Amifostine for Nasoduodenal Delivery) in Combination With Sterotactic Body Radiotherapy for Treatment in Patients With Locally Advanced Pancreatic Cancer.
Xerient Pharma
NCT06305247 ACTIVE NOT RECRUITING A Study to Assess IPN01194 When Administered Alone in Adults With Advanced Solid Tumours
Ipsen
NCT06710756 RECRUITING Lead-212 PSV359 Therapy for Patients With Solid Tumors
Perspective Therapeutics
NCT07478523 RECRUITING FAPI-PET Value for the Initial Screening of Pancreatic and Biliary Cancers
University Hospital, Bordeaux
NCT07214298 RECRUITING Pegcetacoplan in Combination With Modified FOLFIRINOX for the Treatment of Metastatic Pancreatic Ductal Adenocarcinoma
Roswell Park Cancer Institute
NCT04887805 ACTIVE NOT RECRUITING Lenvatinib and Pembrolizumab Maintenance Therapy for the Treatment of Patients of Advanced Unresectable Pancreatic Cancer
City of Hope Medical Center
NCT06710132 RECRUITING Study of Anti-CEACAM5 ADC M9140 in Participants With Advanced Solid Tumors (PROCEADE PanTumor)
EMD Serono Research & Development Institute, Inc.
NCT07255404 RECRUITING A Clinical Trial Testing the Safety of BNT327 (an Investigational Drug) and How Well it Works When Combined With Chemotherapy for People Who Have Not Been Treated Yet for Pancreatic Cancer
BioNTech SE
NCT06844422 RECRUITING Adapted Guided Stereotactic Body Radiotherapy Combined With Chemotherapy and Enhancement of Novel Drug Ivonescimab for Pancreatic Cancer (ASCEND)
Shandong Cancer Hospital and Institute
NCT05988918 ACTIVE NOT RECRUITING Multicenter Trial of ESK981 in Patients With Select Solid Tumors
University of Michigan Rogel Cancer Center
NCT03190941 RECRUITING Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients
National Cancer Institute (NCI)
NCT05985655 RECRUITING Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors
Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals, Inc.
NCT06128551 RECRUITING Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
Revolution Medicines, Inc.
NCT03682289 ACTIVE NOT RECRUITING Ceralasertib (AZD6738) Alone and in Combination With Olaparib or Durvalumab in Patients With Solid Tumors
Rahul Aggarwal
NCT06483555 RECRUITING Basal-like PDAC Treated With Gemcitabine, Erlotinib, and Nab-paclitaxel
UNC Lineberger Comprehensive Cancer Center
NCT06921928 RECRUITING Study for AZD4360 in Participants With Advanced Solid Tumours
AstraZeneca
NCT07450859 RECRUITING A Study of Nuzefatide Pevedotin (BT5528) in Patients With Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)
BicycleTx Limited
NCT06423326 RECRUITING Gemcitabine, Cisplatin and Nab-Paclitaxel as Neoadjuvant Treatment for Patients With Resectable or Borderline Resectable Pancreatic Cancer
Emory University
NCT07020221 RECRUITING A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors
Verastem, Inc.
NCT06922591 RECRUITING Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients
Tango Therapeutics, Inc.
NCT07542002 RECRUITING Liposomal Irinotecan, 5-fluorouracil/Calcium Folinate, Oxaliplatin, and Adebrelimab in Combination With Radiotherapy for Resectable or Borderline Resectable Pancreatic Cancer With Risk Factors:A Prospective Exploratory Study
Ningbo Medical Center Lihuili Hospital
NCT07539155 NOT YET RECRUITING Intratumoral MMR Vaccine Injection in Borderline Resectable/Unresectable Pancreatic Cancer
University of Arkansas
NCT03301805 NOT YET RECRUITING A Phase II, EvaluateBLEX 404 Combined With Gemcitabine Monotherapy With Pancreatic Cancer
Rgene Corporation
NCT05632328 ACTIVE NOT RECRUITING AGEN1423 and Botensilimab w/ or w/o Chemo in PDAC
Bruno Bockorny
NCT03485209 ACTIVE NOT RECRUITING Efficacy and Safety Study of Tisotumab Vedotin for Patients With Solid Tumors
Seagen, a wholly owned subsidiary of Pfizer
NCT07444541 NOT YET RECRUITING ANO31905 in Combination With Chemotherapy for CLDN18.2-Positive Locally Advanced Unresectable or Metastatic Pancreatic Cancer
Anova Innovation Limited
NCT04940286 ACTIVE NOT RECRUITING Gemcitabine, Nab-paclitaxel, Durvalumab, and Oleclumab Before Surgery for the Treatment of in Resectable/Borderline Resectable Primary Pancreatic Cancer
M.D. Anderson Cancer Center
NCT06453486 RECRUITING A Study of High Dose Radiation Therapy for Locally Advanced Pancreatic Cancer That Responded to Initial Chemotherapy Treatment
University Health Network, Toronto
NCT07283705 RECRUITING A Phase II Study Evaluating BMS-986504 in MTAP-deleted Pancreatic Cancer
M.D. Anderson Cancer Center
NCT07488676 RECRUITING A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors
Astellas Pharma Global Development, Inc.
NCT07126158 RECRUITING Stereotactic Body Radiotherapy Plus FAK and RAF/MEK Inhibition in Advanced Pancreatic Adenocarcinoma
Washington University School of Medicine
NCT06659705 RECRUITING Cutting Edge Imaging With PET-FAPI for Earlier Pancreatic Cancer Diagnosis (INDIGO-FAPI)
Institut Curie
NCT07353645 RECRUITING KRAS Neoantigen Nanovaccine as Adjuvant Therapy for Colorectal Cancer/Pancreatic Cancer
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
NCT05065801 RECRUITING Efficacy of Gembrax Followed by Folfirinox Versus Folfirinox Alone in First Metastatic Line Pancreatic Cancer Patients
Institut du Cancer de Montpellier - Val d'Aurelle
NCT07438106 RECRUITING A Phase II Study of HRS-4642 Combined With AG (Nab-paclitaxel and Gemcitabine) as Conversion Therapy for Locally Advanced Pancreatic Cancer
The First Affiliated Hospital with Nanjing Medical University
NCT04895709 RECRUITING A Study of BMS-986340 as Monotherapy and in Combination With Nivolumab or Docetaxel in Participants With Advanced Solid Tumors
Bristol-Myers Squibb
NCT07223047 RECRUITING A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies
Bristol-Myers Squibb
NCT07114861 RECRUITING The KN510713 Study in Combination With mFOLFIRINOX
New Cancer Cure-Bio Co.,Ltd.
NCT05257993 RECRUITING Study to Assess the Safety, Tolerability of JPI-547 in Combination With Modified FOLFIRINOX or Gemcitabine-nab-paclitaxel in Patients With Locally Advanced and Metastatic Pancreatic Cancer
Onconic Therapeutics Inc.
NCT05053971 RECRUITING Testing A New Anti-cancer Drug Combination, Entinostat and ZEN003694, for Advanced and Refractory Solid Tumors
National Cancer Institute (NCI)
NCT05077800 ACTIVE NOT RECRUITING FOLFIRINOX + Elraglusib + Losartan In Pancreatic Cancer
Colin D. Weekes, M.D., PhD
NCT06790602 RECRUITING Cemiplimab Plus Gemcitabine in Patients With Metastatic Pancreatic Adenocarcinoma
University of California, San Diego
NCT05945823 ACTIVE NOT RECRUITING Phase 2 Futibatinib in Combination With PD-1 Antibody Based Standard of Care in Solid Tumors
Taiho Oncology, Inc.
NCT06695845 RECRUITING A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors
Jazz Pharmaceuticals
NCT05624918 RECRUITING A Study of NovoTTF-200T(P) in Combination With Gemcitabine and Nab-Paclitaxel for Resectable Pancreatic Adenocarcinoma
Ashish Manne
NCT02830724 RECRUITING Administering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to People With CD70 Expressing Cancers
National Cancer Institute (NCI)
NCT03678883 ACTIVE NOT RECRUITING 9-ING-41 in Patients With Advanced Cancers
Actuate Therapeutics Inc.
NCT06850623 RECRUITING Acoustic Cluster Therapy (ACT) With Chemotherapy for the Treatment of Locally Advanced Pancreatic Cancer
EXACT Therapeutics AS
NCT04820179 ACTIVE NOT RECRUITING Atezolizumab + Cabozantinib in Patients w/ Metastatic, Refractory Pancreatic Cancer
University of Arizona
NCT06445062 RECRUITING Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
Revolution Medicines, Inc.
NCT06821997 RECRUITING NALIRIFOX Before Surgery for the Treatment of Borderline Resectable Pancreatic Ductal Adenocarcinoma, Nectar Trial
Roswell Park Cancer Institute
NCT07504263 NOT YET RECRUITING Phase 1/2a Study of RP-001 in Participants With Advanced Malignancies
Recurv Pharma Inc
NCT07504471 RECRUITING Hepatic Arterial Infusion of Sodium Bicarbonate (NaHCO3) Combined With NASOX Regimen and Programmed Death-1 (PD-1) Inhibitors for Pancreatic Cancer Liver Metastases
Ruijin Hospital
NCT06904378 RECRUITING ONT01 and Gemcitabine/Nab-paclitaxel as Second Line Therapy for Metastatic Pancreatic Ductal Adenocarcinoma
Washington University School of Medicine
NCT07483983 RECRUITING Study Investigating ASP3082 in Patients With Metastatic/Locally Advanced Non-small-cell Lung Cancer (NSCLC) and Pancreatic Ductal Adenocarcinoma (PDAC), With Biomarker Analysis to Characterize Response/Resistance
Gustave Roussy, Cancer Campus, Grand Paris
NCT07432633 RECRUITING [18F]FPyQCP PET Imaging of Fibroblast Activation Protein in Selected Oncology Indications
Blue Earth Diagnostics
NCT05825066 RECRUITING Neoadjuvant Chemotherapy for Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma
Wake Forest University Health Sciences
NCT07483554 NOT YET RECRUITING IBI343 in Combination Therapy for Advanced Malignant Solid Tumors
Innovent Biologics (Suzhou) Co. Ltd.
NCT07480928 RECRUITING Dual-Targeting CAR-NK Cells Targeting Mesothelin (MSLN) and MUC1 in Advanced Pancreatic Ductal Adenocarcinoma
Beijing Biotech
NCT07163273 RECRUITING Monthly Alternating NALIRIFOX and GnP in the First-Line Setting for Metastatic Pancreatic Ductal Adenocarcinoma
Northwell Health
NCT06412510 RECRUITING Prehabilitation for EOC, Fallopian Tube, Primary Peritoneal Carcinoma and Pancreatic Cancer w/ NACT
Case Comprehensive Cancer Center
NCT04657068 RECRUITING A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
Artios Pharma Ltd
NCT06244771 RECRUITING A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors
Frontier Medicines Corporation
NCT06492915 ACTIVE NOT RECRUITING Chiauranib in Patients With Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma
Chipscreen Biosciences, Ltd.
NCT03384238 RECRUITING Panitumumab-IRDye800 in Patients With Pancreatic Cancer Undergoing Surgery
George Poultsides
NCT05726864 ACTIVE NOT RECRUITING A Study of ELI-002 7P in Subjects With KRAS/NRAS Mutated Solid Tumors
Elicio Therapeutics
NCT07477418 NOT YET RECRUITING PDAC Regression and Intraoperative Surgical Margin With Neoadjuvant TAMP (PRISM-TAMP)
University of Vermont
NCT06756074 RECRUITING Reinforced Pancreaticojejunostomy With or Without glubran2
Minia University
NCT07475234 NOT YET RECRUITING Rimegepant Combined With AG Chemotherapy As First-Line Treatment For Metastatic Pancreatic Ductal Adenocarcinoma
Xiuchao Wang
NCT06479239 RECRUITING Study of EGFRBi Armed Fresh PBMC in Metastatic or Unresectable Pancreatic Cancer
University of Virginia
NCT07469956 NOT YET RECRUITING Surufatinib Plus mFOLFIRINOX and PD-1 Inhibitor as the Neoadjuvant Therapy for High-risk or Borderline Resectable Pancreatic Cancer
Sun Yat-sen University
NCT06008288 RECRUITING A Phase II Study Evaluating JAB-21822 Monotherapy in Adult Patients With Pancreatic Cancer and Other Solid Tumors Harboring the KRAS p.G12C Mutation.
Allist Pharmaceuticals, Inc.
NCT03816163 ACTIVE NOT RECRUITING A Study of Zolbetuximab (IMAB362) in Adults With Pancreatic Cancer
Astellas Pharma Global Development, Inc.
NCT07435038 NOT YET RECRUITING Study of BPI-572270 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS
Betta Pharmaceuticals Co., Ltd.
NCT06821503 RECRUITING Clinical Study Evaluating the Safety, Tolerability, and Preliminary Efficacy of LM-108 ± Penpulimab+Chemotherapy in Advanced Solid Tumors - Cohort C
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT06646055 ACTIVE NOT RECRUITING AK112 and Cadonilimab Combined With Chemotherapy for 1L Treatment of Metastatic Pancreatic Cancer
Akeso
NCT07199764 RECRUITING Maintenance Combinatorial Myeloid Immunotherapy for Unresectable Pancreatic Cancer
University of Pennsylvania
NCT02568267 ACTIVE NOT RECRUITING Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions)
Hoffmann-La Roche
NCT06895031 RECRUITING Study of JYP0015 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS
Guangzhou JOYO Pharma Co., Ltd
NCT04683315 RECRUITING PurIST Classification-Guided Adaptive Neoadjuvant Chemotherapy by RNA Expression Profiling of EUS Aspiration Samples
Medical College of Wisconsin
NCT07114315 RECRUITING A Study of AK130 in Combination With AK112 for the Treatment of Advanced Pancreatic Cancer
Akeso
NCT07446270 NOT YET RECRUITING Efficacy of Tunlametinib in Combination With Anti-EGFR Monoclonal Antibody in Patients With RAS-Mutated Advanced Gastrointestinal Malignancies
Chinese PLA General Hospital
NCT07049055 RECRUITING A Clinical Trial to Evaluate EDV Nanocell Therapy With Gemcitabine and Nab-paclitaxel in Pancreatic Cancer
Engeneic Pty Limited
NCT06048484 RECRUITING Combination Therapy in Patients With Localized Pancreatic Ductal Adenocarcinoma
Gulam Manji
NCT03483038 ACTIVE NOT RECRUITING A Study of the Safety and Activity of Liposomal Irinotecan in Combination With the 5-FU and Oxaliplatin in the Preoperative Treatment of Pancreatic Adenocarcinoma
University of Florida
NCT07006077 RECRUITING Recombinant Human IL-21-expressing Oncolytic Vaccinia Virus Injection (hV01) in Advanced Pancreatic Cancer
Hangzhou Converd Co., Ltd.
NCT05642962 ACTIVE NOT RECRUITING Pancrelipase in People With Pancreatic Ductal Adenocarcinoma (PDAC)
Memorial Sloan Kettering Cancer Center
NCT04605913 RECRUITING Nab-Paclitaxel + Cisplatin + Gemcitabine + TTF in pt. w/ Metastatic PAC
Mayo Clinic
NCT06005493 RECRUITING Study of AZD5863 in Adult Participants With Advanced or Metastatic Solid Tumors
AstraZeneca
NCT04644068 ACTIVE NOT RECRUITING Study of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignancies
AstraZeneca
NCT07410676 RECRUITING EBNK-001 Allogeneic NK Cells With Low-Dose IL-15 ± Pembrolizumab in Advanced Solid Tumors
Essen Biotech
NCT04666740 ACTIVE NOT RECRUITING A Study of Pembrolizumab and Olaparib for People With Metastatic Pancreatic Ductal Adenocarcinoma and Homologous Recombination Deficiency or Exceptional Treatment Response to Platinum-Based Therapy
Memorial Sloan Kettering Cancer Center
NCT07030257 RECRUITING Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors
Tasca Therapeutics
NCT07410494 RECRUITING Biomarker-Guided Allogeneic Single-Target or Dual-Target CAR-NK Cell Therapy for Advanced Solid Tumors
Essen Biotech
NCT07415525 NOT YET RECRUITING IBI343 Combined With Chemotherapy as Neoadjuvant Therapy in Borderline Resectable Pancreatic Cancer
Zhejiang University
NCT06906562 RECRUITING A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations
Sameek Roychowdhury
NCT07240766 RECRUITING HRS-4642 in Combination With Nimotuzumab and Chemotherapy for BRPC With KRAS G12D Mutation
Zhejiang University
NCT06384560 RECRUITING Neoadjuvant Triple Therapy for (Borderline) Resectable Pancreatic Cancer (PREOPANC-5)
Amsterdam UMC, location VUmc
NCT05466799 ACTIVE NOT RECRUITING FOLFIRINOX Versus OncoSil™ in Addition to FOLFIRINOX in Patients With Locally Advanced Pancreatic Adenocarcinoma
OncoSil Medical Limited
NCT05558982 ACTIVE NOT RECRUITING BXCL701 and Pembrolizumab in Patients With Metastatic Pancreatic Ductal Adenocarcinoma
Georgetown University
NCT06219941 RECRUITING AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2
AstraZeneca
NCT04115163 RECRUITING Biologically Optimized Infusion Schedule of Gemcitabine and Nab-Paclitaxel for the Treatment of Metastatic Pancreatic Cancer
Anne Noonan
NCT05908747 ACTIVE NOT RECRUITING Efficacy and Safety of Surufatinib Combined With Gemcitabine and Albumin-bound Paclitaxel in the Peri-operative Treatment of Pancreatic Cancer
Tianjin Medical University Cancer Institute and Hospital
NCT03851614 ACTIVE NOT RECRUITING Study of DNA Damage, Angiogenesis, and PD-L1 Inhibitors in Advanced Solid Tumors
University Health Network, Toronto
NCT06662006 RECRUITING Nal-IRI/5-FU/LV Chemotherapy Combined With PD-L1 Inhibitor and Multi-target Anti-angiogenic Small Molecule±SBRT as Second-line Therapy in Metastatic Pancreatic Cancer Patients
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
NCT07386704 ENROLLING BY INVITATION Nimotuzumab Combined With Chemoradiotherapy in the Treatment of Unresectable Locally Advanced or Oligometastatic Pancreatic Cancer
Peking University First Hospital
NCT06381154 RECRUITING Photoradiation With Verteporfin to Facilitate Immunologic Activity of Pembrolizumab in Unresectable, Locally Advanced or Metastatic Pancreatic Cancer
Mayo Clinic
NCT07377526 NOT YET RECRUITING Phase 1/2 Study TROP2 CAREngineered Cord Blood-Derived NK Cells + Belzutifan In Pancreatic Cancer
M.D. Anderson Cancer Center
NCT07148128 RECRUITING Phase 1/2a Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of WEF-001 as Monotherapy in Advanced KRAS-Mutant Solid Tumours.
Auricula Biosciences Inc.
NCT06951997 RECRUITING QL1706 Plus Chidamide, AG as First-line Treatment for Metastatic Pancreatic Cancer
Tianjin Medical University Cancer Institute and Hospital
NCT07312422 RECRUITING LDRT Combined With Pucotenlimab and Standard Therapy for Advanced Pancreatic Cancer: A Single-Arm Study
Zhejiang Provincial People's Hospital
NCT04098237 ACTIVE NOT RECRUITING Pancreaze (Pancrelipase) for Patients With Pancreatic Adenocarcinoma With Cachexia and Exocrine Pancreatic Insufficiency
Andrew Hendifar, MD
NCT06428409 RECRUITING A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)
Merck Sharp & Dohme LLC
NCT02584244 RECRUITING Feasibility of the LUM Imaging System for Detection of Gastrointestinal Cancers
Lumicell, Inc.
NCT06168812 ACTIVE NOT RECRUITING A Study of Glipizide to Treat High Blood Sugar in People With Pancreatic Cancer
Memorial Sloan Kettering Cancer Center
NCT07342725 NOT YET RECRUITING Phase Ib/II Study to Evaluate the Safety and Efficacy of IBI363 in Combination With Chemotherapy as Second-Line Therapy for Unresectable Locally Advanced or Metastatic Pancreatic Cancer
Ruijin Hospital
NCT05688215 RECRUITING Zimberelimab and Quemliclustat in Combination With Chemotherapy for the Treatment of Patients With Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma
Jonsson Comprehensive Cancer Center
NCT07344220 ENROLLING BY INVITATION Metastatic Non-Familial Adenocarcinoma Maintenance Therapy With DZ-002: Heptamine Carboxymethine Dye Conjugate
Hoag Memorial Hospital Presbyterian
NCT04539808 ACTIVE NOT RECRUITING NeoOPTIMIZE: Early Switching of mFOLFIRINOX or Gemcitabine/Nab-Paclitaxel Before Surgery for the Treatment of Resectable, Borderline Resectable, or Locally-Advanced Unresectable Pancreatic Cancer
OHSU Knight Cancer Institute
NCT07296341 RECRUITING HRS-4642 Combination With Other Antitumor Therapies in Patients With Solid Tumors
Shanghai Hengrui Pharmaceutical Co., Ltd.
NCT06334432 ACTIVE NOT RECRUITING Safety and Efficacy Study of NUV-1511 in Adult Patients With Advanced Solid Tumors
Nuvation Bio Inc.
NCT03977233 RECRUITING Tumor Subtypes in Subjects on FOLFIRINOX With Non-Metastatic Pancreatic Cancer
UNC Lineberger Comprehensive Cancer Center
NCT05651022 ACTIVE NOT RECRUITING Study of DECOY20 With or Without Tislelizumab in Patients With Advanced Solid Tumors
Indaptus Therapeutics, Inc
NCT03104439 ACTIVE NOT RECRUITING Nivolumab and Ipilimumab and Radiation Therapy in MSS and MSI High Colorectal and Pancreatic Cancer
Massachusetts General Hospital
NCT07333287 NOT YET RECRUITING A Multicenter Single-arm Prospective Clinical Study on First-line Treatment of Pancreatic Cancer Liver Metastases With Arterial Infusion Chemotherapy and Embolization Combined With Dual Immune Checkpoint Inhibitors.
Shandong Provincial Hospital
NCT03322995 RECRUITING Pancreatic Cancer Adaptive Neoadjuvant Chemotherapy Trial
Medical College of Wisconsin
NCT06399757 RECRUITING A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors
Apollo Therapeutics Ltd
NCT04241276 ACTIVE NOT RECRUITING A Randomised Trial of ATRA in a Novel Drug Combination for Pancreatic Cancer
Queen Mary University of London
NCT06547736 RECRUITING Exploratory Platform Research on Precision Therapy of Advanced Pancreatic Cancer
Fudan University
NCT07131514 RECRUITING HRS-4642 in Combination With Gemcitabine and Albumin-bound Paclitaxel and Adebrelimab for Neoadjuvant and Adjuvant Treatment of Pancreatic Cancer
Ruijin Hospital
NCT07110064 RECRUITING QL1706+Lenvatinib+AG Regimen as First-line Treatment for Advanced Metastatic Pancreatic Cancer
Du Juan
NCT07235202 RECRUITING A Study of MR001 Combined With Chemotherapy in Patients With Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma (PDAC) After First-line Therapy
Shenzhen Majory Biotechnology Co., Ltd.
NCT07306286 RECRUITING Cryoablation Combined With the Dual-Function Antibody PD-1/CTLA-4 for the Treatment of LAPC Following Failure of First-Line AG Therapy
Ruijin Hospital
NCT07306273 RECRUITING IRE Combined With the Dual-Function Antibody PD-1/CTLA-4 for the Treatment of LAPC Following Failure of First-Line AG Therapy
Ruijin Hospital
NCT06861452 RECRUITING Phase I/IIa Study: RR001 Administered Following Chemotherapy Cycles for Patients With Locally Advanced Pancreatic Carcinoma
EIR Biotherapies s.r.l.
NCT04146298 RECRUITING Mutant KRAS G12V-specific TCR Transduced T Cell Therapy for Advanced Pancreatic Cancer
Changhai Hospital
NCT03991962 ACTIVE NOT RECRUITING Phase II Study to Evaluate Modified Folfirinox and Stereotactic Body Radiation Therapy in Non-metastatic Unresectable Pancreatic Adenocarcinoma
Yale University
NCT07301229 NOT YET RECRUITING A Phase II Clinical Study to Evaluate HLX43 in Subjects With Advanced Pancreatic Cancer
Shanghai Henlius Biotech
NCT07303465 RECRUITING To Evaluate the Safety and Efficacy of RNK08954 in Patients With Metastatic Pancreatic Ductal Adenocarcinoma.
Ranok Therapeutics (Hangzhou) Co., Ltd.
NCT07226856 RECRUITING BMS-986340 in Combination With Nivolumab, Gemcitabine and Nab-paclitaxel for the Treatment of Metastatic and Recurrent Pancreatic Adenocarcinoma
Mayo Clinic
NCT05249101 ACTIVE NOT RECRUITING A Study of Ivaltinostat Plus Capecitabine or Capecitabine in Metastatic Pancreatic Adenocarcinoma
CG Pharmaceuticals, Inc
NCT04396821 ACTIVE NOT RECRUITING A Trial to Evaluate Safety and Tolerability of TST001 in Advanced or Metastatic Solid Tumors
Suzhou Transcenta Therapeutics Co., Ltd.
NCT02955940 ACTIVE NOT RECRUITING An Open-Label Study to Enable Continued Treatment Access for Subjects Previously Enrolled in Studies of Ruxolitinib
Incyte Corporation
NCT07284277 RECRUITING TTFields and Chemotherapy in Metastatic Pancreatic Adenocarcinoma (mPDAC)
Clinica Universidad de Navarra, Universidad de Navarra
NCT04858009 RECRUITING Hyperthermic Intraperitoneal Chemotherapy for the Treatment of Pancreatic Cancer and Peritoneal Metastasis
Mayo Clinic
NCT04390399 ACTIVE NOT RECRUITING Combination Immunotherapy Plus Standard-of-Care Chemotherapy Versus Standard-of-Care Chemotherapy for the Treatment of Locally Advanced or Metastatic Pancreatic Cancer
ImmunityBio, Inc.
NCT07280377 ACTIVE NOT RECRUITING A Study in Advanced or Metastatic Gastrointestinal Cancers Exploring Treatment Combinations With Pelareorep and Atezolizumab
Oncolytics Biotech
NCT03556228 RECRUITING VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma
VM Oncology, LLC
NCT07277452 NOT YET RECRUITING Nimotuzumab Combined With Nab-paclitaxel/Gemcitabine in the Perioperative Treatment of High-risk Resectable/Borderline Resectable Pancreatic Cancer
The First Affiliated Hospital with Nanjing Medical University
NCT06943521 RECRUITING A Study of MT-4561 in Patients With Various Advanced Solid Tumors
Tanabe Pharma America, Inc.
NCT06584227 RECRUITING Adebrelimab and Chidamide for Pancreatic Cancer
Liu Xiufeng
NCT07269626 RECRUITING PULSAR in Systemic Therapy for Pancreatic Cancer
Samsung Medical Center
NCT02481635 ACTIVE NOT RECRUITING A Study of Gemcitabine/Nab-paclitaxel and Radiation Therapy Followed by Surgery in Patients With Advanced Pancreatic Cancer
University Health Network, Toronto
NCT04570943 RECRUITING Sequential Treatment With GEMBRAX and Then FOLFIRINOX Followed by Stereotactic MRI-guided Radiotherapy in Patients With Locally Advanced Pancreatic Cancer
Institut du Cancer de Montpellier - Val d'Aurelle
NCT04753879 RECRUITING Multi-agent Low Dose Chemotherapy GAX-CI Followed by Olaparib and Pembro in Metastatic Pancreatic Ductal Cancer.
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT02451982 ACTIVE NOT RECRUITING Platform Study of Neoadjuvant and Adjuvant Immunotherapy for Patients With Resectable Adenocarcinoma of the Pancreas
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT06782932 RECRUITING Comparing Neoadjuvant/Adjuvant GVAX vs a mKRASvax Given With Anti-PD-1 and Anti-CD137 for Surgically Resectable Pancreatic Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT06333314 RECRUITING Dostarlimab for Locally Advanced or Metastatic Cancer (Non-colorectal/Non-endometrial) With Tumor dMMR/MSI
UNICANCER
NCT03608631 RECRUITING iExosomes in Treating Participants With Metastatic Pancreas Cancer With KrasG12D Mutation
M.D. Anderson Cancer Center
NCT07233850 NOT YET RECRUITING A Phase II Clinical Study Evaluating SSGJ-706 in Combination Therapy for Advanced Gastrointestinal Cancers
Shenyang Sunshine Pharmaceutical Co., LTD.
NCT06177522 NOT YET RECRUITING Adebrelimab Combined With Chemotherapy for Neoadjuvant Therapy in Resectable Pancreatic Cancer
Jinling Hospital, China
NCT05438459 RECRUITING GAIA-102 Intraperitoneal Administration in Patients With Advanced Gastrointestinal Cancer of Microsatellite Stable With Malignant Ascites
Kyushu University
NCT07230301 NOT YET RECRUITING Adebrelimab Infusion Plus Standard Care for Pancreatic Cancer With Pleural or Peritoneal Effusions
Sizhen Wang
NCT06773130 RECRUITING HRS-4642 Combined With Nimotuzumab in the Treatment of Recurrent or Metastatic Pancreatic Ductal Adenocarcinoma
West China Hospital
NCT05630183 ACTIVE NOT RECRUITING A Study of Botensilimab in Participants With Metastatic Pancreatic Cancer
Agenus Inc.
NCT05360732 ACTIVE NOT RECRUITING Redefining FOLFIORINOX in Older Pancreatic Cancer Patients
Fox Chase Cancer Center
NCT05379985 RECRUITING Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS
Revolution Medicines, Inc.
NCT04926467 RECRUITING Chemotherapy + Anakinra in Patients With Pancreatic Adenocarcinoma (PDAC)
Baylor Research Institute
NCT06576115 RECRUITING Gemcitabine, Nab-paclitaxel Plus the TheraBionic P1 (an Amplitude-Modulated Radiofrequency Electromagnetic Fields) Device to Treat Metastatic Pancreatic Cancer
Barbara Ann Karmanos Cancer Institute
NCT05482893 RECRUITING Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or ICI, for the Treatment of Patients With Advanced Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study)
Phanes Therapeutics
NCT04821284 ACTIVE NOT RECRUITING Sonoporation and Chemotherapy for the Treatment of Pancreatic Cancer
Flemming Forsberg
NCT03080974 RECRUITING Immunotherapy and Irreversible Electroporation in the Treatment of Advanced Pancreatic Adenocarcinoma
University of Louisville
NCT05706129 RECRUITING A Study to Assess Safety, Tolerability and Imaging Characteristics of [68Ga]Ga-DPI-4452 and to Assess Safety, Tolerability, and Efficacy of [177Lu]Lu-DPI-4452 in Participants With Unresectable Locally Advanced or Metastatic Solid Tumors
ITM Oncologics GmbH
NCT04888312 ACTIVE NOT RECRUITING Safety and Efficacy of Mitazalimab in Combination With Chemotherapy in Pancreatic Cancer Patients
Alligator Bioscience AB
NCT03245541 ACTIVE NOT RECRUITING Radiation Therapy in Combination With Durvalumab for People With Pancreatic Cancer
Memorial Sloan Kettering Cancer Center
NCT07208539 NOT YET RECRUITING AG Followed by FOLFIRINOX Both Combined With PD-L1 Antibodies as a Conversion Therapy for Borderline Resectable and Locally Advanced Pancreatic Cancer.
Shanghai Zhongshan Hospital
NCT03915678 RECRUITING Atezolizumab Combined With BDB001 AnD Immunogenic Radiotherapy in Patients With Advanced Solid Tumors
Institut Bergonié
NCT03492671 RECRUITING Testing the Combination of Two Approved Chemotherapy Drugs and Radiation Prior to Surgery in Localized Pancreatic Cancer
Loma Linda University
NCT05518903 RECRUITING Investigational Scan (68Ga-FAPI-46 PET/CT) for Imaging of Cancer-Associated Fibroblasts for Localized Pancreatic Ductal Adenocarcinoma
Mayo Clinic
NCT03563248 ACTIVE NOT RECRUITING Losartan and Nivolumab in Combination With FOLFIRINOX and SBRT in Localized Pancreatic Cancer
Massachusetts General Hospital
NCT07096362 RECRUITING Utility of ctDNA in Early Switch of First-line mFOLFIRINOX in Metastatic Pancreatic Ductal Adenocarcinoma
University of Miami
NCT05093231 RECRUITING Pembrolizumab With Olaparib as Combined Therapy in Metastatic Pancreatic Cancer
Cambridge University Hospitals NHS Foundation Trust
NCT06747845 RECRUITING Maintenance Niraparib Plus Ipilimumab in Patients With Metastatic Pancreatic Adenocarcinoma Whose Disease Has Not Progressed on Platinum-Based Chemotherapy
Abramson Cancer Center at Penn Medicine
NCT07175389 NOT YET RECRUITING JDB153 Combined With Serplulimab for Pancreatic Cancer After Standard Treatment Failure
West China Hospital
NCT07173387 ACTIVE NOT RECRUITING Stereotactic Body Radiotherapy and NALIRIFOX for Locally Advanced Pancreatic Cancer
Shandong Cancer Hospital and Institute
NCT07172802 RECRUITING A Study of GI-108, an Anti-CD73-IgG4 Fc-IL-2v Bispecific Fusion Protein, as Monotherapy in Patients With Advanced or Metastatic Solid Tumors
GI Innovation, Inc.
NCT06831136 RECRUITING Endoscopic Ultrasound Radiofrequency Ablation and Immunotherapy Pembrolizumab for Locally Advanced Unresectable and Metastatic Pancreatic Duct Adenocarcinoma
The University of Texas Health Science Center, Houston
NCT02598349 RECRUITING Proton Radiation for Unresectable, Borderline Resectable, or Medically Inoperable Carcinoma of the Pancreas
Proton Collaborative Group
NCT06313970 RECRUITING First-line Regimen With QL1706 Plus Chemo ± Bev in PDAC Patients
Fudan University
NCT05585320 ACTIVE NOT RECRUITING A Phase 1/2a Study of IMM-1-104 in Participants With Advanced or Metastatic Solid Tumors
Immuneering Corporation
NCT05451849 ACTIVE NOT RECRUITING A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer
TCR2 Therapeutics
NCT01088789 ACTIVE NOT RECRUITING Boost GVAX Pancreas Vaccine With or Without CY in Patients With Pancreas Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT06587061 RECRUITING HRS-4642 in Combination With AG for Neoadjuvant and Adjuvant Treatment of Pancreatic Cancer
Ruijin Hospital
NCT04111172 ACTIVE NOT RECRUITING A Vaccine (Ad5.F35-hGCC-PADRE) for the Treatment of Gastrointestinal Adenocarcinoma
Thomas Jefferson University
NCT06758544 RECRUITING A Single-arm, Open-label Clinical Study to Evaluate the Efficacy and Safety of VRT106 in Combination With Chemotherapy for Resectable Pancreatic Cancer
Guangdong Provincial People's Hospital
NCT05864144 ACTIVE NOT RECRUITING A Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors
Sensei Biotherapeutics, Inc.
NCT04669197 ACTIVE NOT RECRUITING Study of Paclitaxel Protein Bound + Gemcitabine + Cisplatin + Hydrochloroquine as Treatment in Untreated Pancreas Cancer
HonorHealth Research Institute
NCT06843551 RECRUITING The Miami "EMPIRE" Trial - Eradication of Metastatic Pancreatic Cancer With Immuno-Radiation
Benjamin Spieler
NCT06298916 RECRUITING 64Cu-LNTH-1363S in Patients With Sarcoma or Gastrointestinal Tract Cancer
Lantheus Medical Imaging
NCT05057013 ACTIVE NOT RECRUITING A Phase I/IIa Trial of HMBD-001 in Advanced HER3 Positive Solid Tumours
Cancer Research UK
NCT06196671 NOT YET RECRUITING Oncolytic Virus Plus PD-1 Inhibitor to Patients With Advanced Pancreatic Cancer
Fudan University
NCT06149689 RECRUITING mFOLFIRINOX Plus Radiotherapy to Patients With CA19-9-normal Advanced Pancreatic Cancer
Fudan University
NCT07108504 NOT YET RECRUITING Efficacy and Safety of LM-302 Combined With Gemcitabine CLDN 18.2 Positive Unresectable Locally Advanced or Metastatic Pancreatic Cancer
Shanghai Zhongshan Hospital
NCT07101679 RECRUITING A Study of GnP RegimenCombined With Serplulimab and Stereotactic Body Radiation Therapy as First-line Treatment for Locally Advanced Pancreatic Cancer
West China Hospital
NCT06249321 RECRUITING mFOLFIRINOX Plus Radiotherapy to Patients With CA19-9-normal Advanced Pancreatic Cancer Refractory to Chemotherapy
Fudan University
NCT07097064 NOT YET RECRUITING Evaluation of the Stereotactic MR-guided Adaptive Radiotherapy for Locally Advanced Pancreatic Cancers
Institut du Cancer de Montpellier - Val d'Aurelle
NCT06105021 ACTIVE NOT RECRUITING Phase I Study of Autologous CD8+ and CD4+ Engineered T Cell Receptor T Cells in Subjects With Advanced or Metastatic Solid Tumor
Affini-T Therapeutics, Inc.
NCT05969171 RECRUITING A Single-center, Prospective, Two Cohort Study of Surufatinib Combined With AG or AG in the First-line Treatment of Locally Advanced or Metastatic Pancreatic Cancer
Fudan University
NCT06605430 RECRUITING Medical Cannabis in Patients With Advanced Pancreatic and Colorectal Cancer
HealthPartners Institute
NCT06015724 RECRUITING Anti-CD38 Antibody With KRAS Vaccine and Anti-PD-1 Antibody in Subjects With Pancreatic Ductal Adenocarcinoma and Refractory Non-Small Cell Lung Cancer
Georgetown University
NCT03806309 ACTIVE NOT RECRUITING OSE2101+FOLFIRI, or FOLFIRI Maintenance After FOLFIRINOX-based Induction Therapy in Advanced or Metastatic PDAC
GERCOR - Multidisciplinary Oncology Cooperative Group
NCT04348045 ACTIVE NOT RECRUITING Maintenance With Olaparib or Selumetinib + Durvaluma for m-PDAC Guided by BRCAness and KRAS Status.
GERCOR - Multidisciplinary Oncology Cooperative Group
NCT05604560 ACTIVE NOT RECRUITING A Neoadjuvant Study of Tislelizumab and SX-682 for Resectable Pancreas Cancer
Lei Zheng
NCT06266143 ACTIVE NOT RECRUITING A Trial of Y101D in Combination With Gemcitabine and Albumin Paclitaxel in Patients With Advanced Pancreatic Cancer
Wuhan YZY Biopharma Co., Ltd.
NCT06024824 RECRUITING Dose-Painted Intensity Modulated Radiotherapy Pancreas (DP-IMRT Pancreas)
Cancer Trials Ireland
NCT05132504 RECRUITING Neoadjuvant Folfirinox Combined With Pembrolizumab Followed by Surgery for Patients With Resectable Pancreatic Cancer
Baylor College of Medicine
NCT07066995 RECRUITING Mesothelin and Claudin 18.2 Dual-Target CAR-T Therapy in Advanced Pancreatic Cancer
Essen Biotech
NCT03935893 RECRUITING Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers
Udai Kammula
NCT04098081 ACTIVE NOT RECRUITING 1911GCCC: Galeterone With Gemcitabine for Patients With Metastatic Pancreatic Adenocarcinoma
University of Maryland, Baltimore
NCT07028424 NOT YET RECRUITING PANORAMIX : Optimizing 1st-line NALIRIFOX and Exploring Microbiota's Role in 2nd Line Pancreatic Cancer Treatment
GERCOR - Multidisciplinary Oncology Cooperative Group
NCT06825546 RECRUITING Icaritin in Combination With AG in Patients With Previously Untreated Advanced Pancreatic Ductal Adenocarcinoma
Sir Run Run Shaw Hospital
NCT03175224 RECRUITING APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors
Apollomics Inc.
NCT04901741 NOT YET RECRUITING Olaptesed With Pembrolizumab and Nanoliposomal Irinotecan or Gemcitabine/Nab-Paclitaxel in MSS Pancreatic Cancer
TME Pharma AG
NCT07040228 RECRUITING A Phase Ib/II Clinical Study of Regorafenib Combined With Toripalimab and Albumin-bound Paclitaxel for the Third-line Treatment of Advanced Pancreatic Cancer
Junjie Hang
NCT05451043 RECRUITING Durvalumab and Tremelimumab in Combination With Propranolol and Chemotherapy for Treatment of Advanced Hepatopancreabiliary Tumors (BLOCKED)
AHS Cancer Control Alberta
NCT06435260 RECRUITING Hypofractionated Radiotherapy +Chemotherapy+ Camrelizumab as Neoadjuvant Therapy for Pancreatic Cancer
Hebei Medical University Fourth Hospital
NCT04543071 RECRUITING Chemo4METPANC Combination Chemokine Inhibitor, Immunotherapy, and Chemotherapy in Pancreatic Adenocarcinoma
Gulam Manji
NCT06135896 RECRUITING Tripegfilgrastim Trial to Reduce the Risk of Severe Neutropenia in Patients With Unresectable Pancreaticobiliary Cancers
National Cancer Center, Korea
NCT02843945 RECRUITING Initial Feasibility Study to Treat Borderline Resectable Pancreatic Cancer With a Planar LDR Source
CivaTech Oncology
NCT03856658 ACTIVE NOT RECRUITING Hepatic Artery Infusional Floxuridine to Treat Pancreatic Cancer Liver Metastases
Corewell Health West
NCT05929885 RECRUITING Metronomic Capecitabine, Oxaliplatin and UGT1A1 Genotype-directed Irinotecan in Metastatic Pancreatic Cancer Patients
National Cancer Centre, Singapore
NCT04581473 ACTIVE NOT RECRUITING Study to Evaluate the Efficacy, Safety and Pharmacokinetics of CT041 Autologous CAR T-cell Injection
CARsgen Therapeutics Co., Ltd.
NCT05851924 RECRUITING A Study of NALIRIFOX in Combination With Radiation Therapy in People With Pancreatic Ductal Adenocarcinoma (PDAC)
Memorial Sloan Kettering Cancer Center
NCT05141149 RECRUITING First in Human Phase1/2a Clinical Trial of Anti-PAUF Monoclonal Antibody PBP1510 in Patients With Pancreatic Cancer
Prestige Biopharma Limited
NCT06199895 RECRUITING Clinical Efficacy and Safety of Paclitaxel Polymeric Micelles for Injection in the Treatment of Patients With Taxans-resistant Pancreatic Adenocarcinoma, Cholangiocarcinoma, Lung Cancer, Gastric Cancer, Esophageal Carcinoma, or Breast Cancer
Liu Huang
NCT06944106 RECRUITING A Study on Ivonescimab Plus Chemotherapy as Neoadjuvant Therapy for Borderline Resectable Pancreatic Cancer
Tianjin Medical University Cancer Institute and Hospital
NCT04084496 RECRUITING mFOLFIRINOX as Adjuvent Chemotherapy in Treating Chinese Pancreatic Cancer Patients
Sun Yat-sen University
NCT02340117 ACTIVE NOT RECRUITING Study of Combined SGT-53 Plus Gemcitabine/Nab-Paclitaxel for Metastatic Pancreatic Cancer
SynerGene Therapeutics, Inc.
NCT06991491 NOT YET RECRUITING Ivonescimab With GnP and SBRT in Patients With Metastatic Pancreatic Cancer (WGOG-PAN 004)
West China Hospital
NCT03073785 ACTIVE NOT RECRUITING Hypofractionated Stereotactic Body Radiation & Fluorouracil or Capecitabine for Locally Advanced Pancreatic Cancer
University of Nebraska
NCT05827055 ACTIVE NOT RECRUITING Proglumide and Chemotherapy for Metastatic Pancreatic Cancer
Georgetown University
NCT05102721 ACTIVE NOT RECRUITING Trial of Immunotherapy With Avelumab and Pepinemab As Second Line For Patients With Metastatic Pancreatic Adenocarcinoma
Vaccinex Inc.
NCT04990609 RECRUITING EUS-RFA PANCARDINAL-1 Trial
The University of Texas Health Science Center, Houston
NCT06962267 RECRUITING A Clinical Study on the First-line Treatment of Metastatic Pancreatic Cancer With TQB2916 Injection Combined With Gemcitabine Hydrochloride for Injection and Paclitaxel for Injection (Albumin-bound Type)
Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.
NCT02983578 ACTIVE NOT RECRUITING Danvatirsen and Durvalumab in Treating Patients With Advanced and Refractory Pancreatic, Non-Small Cell Lung Cancer, and Mismatch Repair Deficient Colorectal Cancer
M.D. Anderson Cancer Center
NCT04503265 RECRUITING A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies
AtlasMedx, Incorporated
NCT05827796 RECRUITING IN10018+ Standard Chemotherapy (+KN046) in Subjects With Advanced Pancreatic Cancer
InxMed (Shanghai) Co., Ltd.
NCT02912949 ACTIVE NOT RECRUITING A Study of Zenocutuzumab (MCLA-128) in Patients With Solid Tumors Harboring an NRG1 Fusion (eNRGy)
Partner Therapeutics, Inc.
NCT06946901 RECRUITING The Safety and Effectiveness of Hyperthermic Intraperitoneal Chemotherapy Combined With Intravenous Chemotherapy for Peritoneal Metastatic Pancreatic Cancer, a Phase II Clinical Trial
Shanghai Zhongshan Hospital
NCT05736731 ACTIVE NOT RECRUITING A Study to Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Participants With Solid Tumors That Express CEA and Have Lost HLA-A*02 Expression
A2 Biotherapeutics Inc.
NCT06938282 NOT YET RECRUITING An Exploratory Clinical Study of HRS-4642 in Combination With Immunotherapy and Chemotherapy for Pancreatic Cancer
Shanghai Zhongshan Hospital
NCT06938503 NOT YET RECRUITING AG Plus Nimotuzumab Sequential Irreversible Electroporation Ablation for Locally Advanced Pancreatic Cancer
Tianjin Medical University Cancer Institute and Hospital
NCT05915351 ACTIVE NOT RECRUITING Enfortumab Vedotin in Previously Treated Locally Advanced or Metastatic Pancreatic Cancer (EPIC)
University of Kansas Medical Center
NCT06916975 NOT YET RECRUITING Adebrelimab Combined With AG Regimen in Patients With Unresectable Locally Advanced or Metastatic Pancreatic Cancer
Jin Xu
NCT05776524 RECRUITING Study of Amplitude-Modulated Radiofrequency Electromagnetic Fields in Metastatic Pancreatic Cancer
THERABIONIC INC.
NCT06888674 NOT YET RECRUITING Personalized Tumor Neoantigen MRNA Therapy Adjuvant Treatment for Postoperative Pancreatic Cancer.
Zhejiang University
NCT06888648 NOT YET RECRUITING Personalized Tumor Neoantigen MRNA Therapy for Advanced Pancreatic Cancer.
Zhejiang University
NCT04802876 ACTIVE NOT RECRUITING Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients with PD1-high MRNA Expressing Tumors
SOLTI Breast Cancer Research Group
NCT01585805 ACTIVE NOT RECRUITING Gemcitabine Hydrochloride and Cisplatin With or Without Veliparib or Veliparib Alone in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer
National Cancer Institute (NCI)
NCT03579836 RECRUITING Evaluation of Safety and Efficacy in BEY1107 in Monotherapy Gemcitabine Combination in Patient with Pancreatic Cancer
BeyondBio Inc.
NCT06866977 NOT YET RECRUITING A Single-arm, Open-label Clinical Study to Evaluate the Efficacy and Safety of VRT106 in Combination With Chemotherapy for Advanced Pancreatic Cancer
Xiangya Hospital of Central South University
NCT04825288 ACTIVE NOT RECRUITING XB2001 in Combination With ONIVYDE + 5-FU/LV (+Folinic Acid) in Advanced Pancreatic Cancer
XBiotech, Inc.
NCT04381130 NOT YET RECRUITING A Phase I/IIa Study of EF-009 in Patients with Pancreatic Cancer
Everfront Biotech Co., Ltd.
NCT05927142 RECRUITING Combining Anti-PD-L1 Immune Checkpoint Inhibitor Durvalumab With TLR-3 Agonist Rintatolimod in Patients With Metastatic Pancreatic Ductal Adenocarcinoma for Therapy Efficacy
Joachim Aerts, MD PhD
NCT06816914 RECRUITING Perioperative NALIRIFOX (liposomal Irinotecan in Combination with Fluorouracil, Leucovorin, and Oxaliplatin) in Resectable Pancreatic Adenocarcinoma: Randomized Phase II Trial
Taichung Veterans General Hospital
NCT06819215 RECRUITING Phase I/II Clinical Study to Evaluate VB15010 Tablets in Patients With Advanced Solid Tumors
Zhejiang Yangli Pharmaceutical Technology Co., Ltd.
NCT06750861 NOT YET RECRUITING QL1706 Plus Chemotherapy With AG Regime as First-line Treatment of Advanced PDAC
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT06792435 RECRUITING XNW27011 Study of Advanced Solid Tumor Subjects Who Failed Standard Therapies.
Evopoint Biosciences Inc.
NCT06736717 RECRUITING Onvansertib in Combination With NALIRIFOX for First Line Treatment of Advanced Pancreatic Cancer
University of Kansas Medical Center
NCT05472259 RECRUITING A Study Evaluating the Efficacy of 5-FU + NALIRI and 5-FU + NALIRINOX for PDAC (NALPAC)
Belgian Group of Digestive Oncology
NCT05355298 ACTIVE NOT RECRUITING ACCENT: AMP945 in Combination with Nab-paclitaxel and Gemcitabine for Treatment of Pancreatic Cancer
Amplia Therapeutics Limited
NCT05431270 RECRUITING Dose Escalation/Expansion Study of Mavrostobart (PT199), an Anti-CD73 mAb, Administered Alone and in Combination With a PD-1 Inhibitor or Chemotherapy (the MORNINGSTAR Study)
Phanes Therapeutics
NCT06387342 RECRUITING Namodenoson Treatment of Advanced Pancreatic Cancer
Can-Fite BioPharma
NCT06789679 RECRUITING Albumin-Bound Paclitaxel and Gemcitabine With or Without S-1 as First-Line Treatment for Advanced Pancreatic Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT04986930 ACTIVE NOT RECRUITING mFOLFIRINOX With or Without Stereotactic Body Radiotherapy in Locally Advanced Pancreatic Adenocarcinoma
Asan Medical Center
NCT05562297 NOT YET RECRUITING Neoadjuvant/Adjuvant Sintilimab, Nab-paclitaxel, and Gemcitabine for Resectable/Borderline Resectable Pancreatic Cancer
Shanghai Zhongshan Hospital
NCT06782555 RECRUITING A Study of Evofosfamide in Combination with Zalifrelimab and Balstilimab
ImmunoGenesis
NCT06782685 RECRUITING Liposomal Irinotecan + Oxaliplatin + Bevacizumab Versus Liposomal Irinotecan + 5-FU/LV
Dai, Guanghai
NCT06766019 ACTIVE NOT RECRUITING Adebrelimab Combined With Irinotecan Liposomal (II), Oxaliplatin, and 5-FU/LV Conversion Therapy for Locally Advanced Pancreatic Cancer
The First Affiliated Hospital with Nanjing Medical University
NCT04404595 ACTIVE NOT RECRUITING Claudin18.2 CAR-T (CT041) in Patients With Gastric, Pancreatic Cancer, or Other Specified Digestive Cancers
CARsgen Therapeutics Co., Ltd.
NCT06761027 RECRUITING mFOLFIRINOX Plus Anlotinib and Sintilimab for Advanced Pancreatic Cancer
Fujian Provincial Hospital
NCT03368963 ACTIVE NOT RECRUITING TAS102 in Combination With NAL-IRI in Advanced GI Cancers
Emory University
NCT05218889 RECRUITING Surufatinib Plus Camrelizumab and AS in First Line Treatment of Advanced Metastatic Pancreatic Cancer
Chinese PLA General Hospital
NCT04827953 ACTIVE NOT RECRUITING Study to Evaluate the Safety and Efficacy of Treatment With NLM-001 and Standard Chemotherapy Plus Zalifrelimab in Patients With Advanced Pancreatic Cancer
Nelum Corp
NCT06405490 RECRUITING NALIRI-XELOX+AK104 for First-line Treatment of Advanced PDAC
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT05859750 RECRUITING A Study of AK104 With Chemotherapy as First-line Treatment in Patients With Advanced Pancreatic Cancer
Akeso
NCT06722911 RECRUITING Study of Adjuvant Nimotuzumab Combined with Nab-paclitaxel+ Gemcitabine in EGFR-positive Pancreatic Cancer
Zhejiang Provincial People's Hospital
NCT06472037 RECRUITING AG Combined With Cadonilimab Sequential Short-course Radiotherapy in the Treatment of Locally aPDAC
Tianjin Medical University Cancer Institute and Hospital
NCT06700603 NOT YET RECRUITING Second-line Irinotecan Liposome Combination Regimen for Irinotecan-treated Pancreatic Cancer
Rui-hua Xu, MD, PhD
NCT06690528 RECRUITING Conversion Surgery Vs. Palliative Care in Pancreatic Cancer Oligometastatic to the Liver
Azienda Ospedaliera di Padova
NCT06598007 RECRUITING A Study to Determine the Effect of CT3001 in Patients With Advanced Solid Tumors
Crossignal Therapeutics, Inc.
NCT06669078 NOT YET RECRUITING NALIRIFOX Combined With PD-1 Sequential Radiotherapy Versus NALIRIFOX as Conversion Therapy of Locally Advanced Pancreatic Cancer
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
NCT06389760 RECRUITING Nimotuzumab Combined With mFOLFIRINOX/GX as Postoperative Adjuvant Therapy in Pancreatic Cancer
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
NCT06662669 NOT YET RECRUITING YL-13027 and/or HY-0102 Combined With AG Regimen Chemotherapy for Metastatic Pancreatic Cancer
Shanghai YingLi Pharmaceutical Co. Ltd.
NCT05659914 ACTIVE NOT RECRUITING Olaparib and Durvalumab (MEDI4736) in Patients with Metastatic Pancreatic Cancer and DNA Damage Repair Genes Alterations
Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)
NCT05462496 RECRUITING Modulation of the Gut Microbiome With Pembrolizumab Following Chemotherapy in Resectable Pancreatic Cancer
Icahn School of Medicine at Mount Sinai
NCT05620134 ACTIVE NOT RECRUITING Study of JK08 in Patients with Unresectable Locally Advanced or Metastatic Cancer
Salubris Biotherapeutics Inc
NCT04452461 RECRUITING Pancreatic Adenocarcinoma Neoadjuvant Chemotherapy Before Surgery
Hamilton Health Sciences Corporation
NCT04913337 ACTIVE NOT RECRUITING Study of NGM707 As Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumor Malignancies
NGM Biopharmaceuticals, Inc
NCT06621095 NOT YET RECRUITING Anlotinib Plus Benmelstobart and AG in First-line Treatment of Advanced Metastatic Pancreatic Cancer (ALTER-PA-001)
RenJi Hospital
NCT04205227 ACTIVE NOT RECRUITING ENB003 Plus Pembrolizumab Phase 1b/2a in Solid Tumors
ENB Therapeutics, Inc
NCT03269526 ACTIVE NOT RECRUITING BATs Treatment for Pancreatic Cancer, Phase Ib/II
University of Virginia
NCT06261359 RECRUITING A Study of CEND-1 With Chemotherapy as First-Line Therapy in Patients With Pancreatic Ductal Adenocarcinoma
Qilu Pharmaceutical Co., Ltd.
NCT06224387 RECRUITING CTS2190 Phase I /II Clinical Study in Patients
CytosinLab Therapeutics Co., Ltd.
NCT06475326 RECRUITING Adebrelimab in Combination With NALIRIFOX in Locally Advanced Pancreatic Cancer
Fudan University
NCT06427239 RECRUITING Exploratory Clinical Study of HRS-4642 Combined With Adebelimab in the Treatment of Advanced Pancreatic Cancer
Fudan University
NCT06531278 RECRUITING Adebelimab Combined With Irinotecan Liposomal Injection, Oxaliplatin, Fluorouracil and Calcium Folinate Are Used in the First-line Treatment of Pancreatic Cancer Liver Metastasis Efficacy and Safety
Jiang Long
NCT06513455 NOT YET RECRUITING Irinotecan Liposome,Albumin Paclitaxel and Gemcitabine First-line Treatment for Pancreatic Cancer
Harbin Medical University
NCT06387810 RECRUITING Irinotecan Liposome II in Combination With 5-FU/LV and Oxaliplatin in Perioperative Treatment of Borderline Resectable Pancreatic Cancer
Peking Union Medical College Hospital
NCT06491472 RECRUITING Ivonescimab(AK112/SMT112) in Combination With Stereotactic Body Radiation Therapy and Chemotherapy in Patients With Pancreatic Cancer
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
NCT06454448 RECRUITING Phase Ib/II Clinical Study of Adebrelimab in Combination With Decitabine, Albumin-bound Paclitaxel, and Gemcitabine for the First-line Treatment of Metastatic Pancreatic Cancer
Tianjin Medical University Cancer Institute and Hospital
NCT06359275 RECRUITING PD-1 Combined With Chemotherapy and PULSAR in LAPC and Local Recurrence Patients
Fudan University
NCT06467565 RECRUITING NALIRIFOX as Induction Therapy in LAPC
The First Affiliated Hospital with Nanjing Medical University
NCT05766748 RECRUITING Study of Effect of Azeliragon in Patients Refractory to Prior Treatment of Metastatic Pancreatic Cancer
Cantex Pharmaceuticals
NCT06018896 RECRUITING Vitamin C to Quality of Life in Patients With Terminal Stage Pancreatic Cancer
Fudan University
NCT06436976 RECRUITING The Effect of Probiotics ATG-F4 in Cancer Patients
Chungnam National University Hospital
NCT06429904 ACTIVE NOT RECRUITING Nimotuzumab Plus NALIRIFOX in Locally Advanced Pancreatic Cancer
Peking Union Medical College Hospital
NCT06427460 RECRUITING Central-boost Ablative Radiation Therapy for Solid Tumors (CBART)
Changhai Hospital
NCT06422156 NOT YET RECRUITING SBRT Combined With Nimotuzumab and Mono-chemotherapy in Locally Advanced Pancreatic Cancer
Peking University Third Hospital
NCT03337087 ACTIVE NOT RECRUITING Liposomal Irinotecan, Fluorouracil, Leucovorin Calcium, and Rucaparib in Treating Patients With Metastatic Pancreatic, Colorectal, Gastroesophageal, or Biliary Cancer
Academic and Community Cancer Research United
NCT04672005 ACTIVE NOT RECRUITING Modified FOLFIRINOX Alternated With Biweekly Gemcitabine Plus Nab-Paclitaxel Untreated Pancreatic Cancer
Lyudmyla Berim
NCT06404840 RECRUITING Evaluating Nimotuzumab in Combination With AG Regimen for Pancreatic Cancer With Liver Metastases : A Prospective, Single-Arm, Phase II Study
Tianjin Medical University Cancer Institute and Hospital
NCT03351296 ACTIVE NOT RECRUITING Two Chemotherapy Regimens Plus or Minus Bevacizumab
Gustave Roussy, Cancer Campus, Grand Paris
NCT06329947 NOT YET RECRUITING A Phase II Study of Surufatinib Combined With Camrelizumab and mFOLFOX6 as Second-line Treatment for Advanced PRAD
Rui-hua Xu, MD, PhD
NCT06078787 RECRUITING Olaparib in PALB2 Advanced Pancreatic Cancer
Azienda Ospedaliero-Universitaria di Modena
NCT04589234 ACTIVE NOT RECRUITING Saltikva for Metastatic Pancreatic Cancer
Salspera LLC
NCT06370754 NOT YET RECRUITING Newly Emerging Immunotherapy for Pancreatic Cancer Treatment
Fudan University
NCT06361030 NOT YET RECRUITING Surufatinib Combined With Gemcitabine Plus Nab-paclitaxel in Locally Advanced Pancreatic Cancer
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
NCT06111274 RECRUITING A Phase 2 Study of ABSK021 in Patients With Advanced Pancreatic Cancer
Abbisko Therapeutics Co, Ltd
NCT06345599 NOT YET RECRUITING PRaG Therapy in Combination With Locally Advanced Pancreatic Ductal Adenocarcinoma (PDAC) (NeoPRAG Study)
Second Affiliated Hospital of Soochow University
NCT06145074 RECRUITING Examining Safety, Efficacy and Feasibility of Preoperative Propranolol in Patients With PDAC.
Zealand University Hospital
NCT06196788 RECRUITING Transcatheter Arterial Infusion to Patients With Advanced Pancreatic Cancer
Fudan University
NCT06259058 NOT YET RECRUITING Stereotactic Body Radiation Therapy Followed by NALIRIFOX vs NALIRIFOX for Borderline Resectable Pancreatic Cancer
Tianjin Medical University Cancer Institute and Hospital
NCT06233877 NOT YET RECRUITING Clinical Trial Evaluating Low Dose G-FLIP Plus Mitomycin C for Stage IV Pancreatic Cancer
Hirschfeld Oncology
NCT06151262 RECRUITING A Study of Trilaciclib Combined With mFOLFIRINOX in the Treatment of Patients With Advanced Pancreatic Cancer
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
NCT05988814 RECRUITING Trial Evaluating the Efficacy and the Safety of FOLFIRINOX3 Treatment in Patients With Unresectable Locally Advanced or Metastatic Pancreatic Cancer in First Line of Chemotherapy
Centre Georges Francois Leclerc
NCT06245330 RECRUITING A Phase I/II Study of AST-001 in Subjects With Advanced Solid Tumors
Ascentawits Pharmaceuticals, Ltd
NCT06234072 NOT YET RECRUITING Comparing Astragalus Plus Gemcitabine to Gemcitabine Alone as Neoadjuvant Treatment for Pancreatic Cancer Patients
Shenzhen University General Hospital
NCT06210360 NOT YET RECRUITING Perioperative Treatment in High-risk Resectable Pancreatic Cancer With NALIRIFOX
Changhai Hospital
NCT06060405 RECRUITING Durvalumab and Oleclumab in Resectable PDAC
University Health Network, Toronto
NCT02446093 ACTIVE NOT RECRUITING Neoadjuvant CAN-2409 in Combination With Chemoradiation or SBRT for Borderline Resectable Pancreatic Adenocarcinoma
Candel Therapeutics, Inc.
NCT06172036 NOT YET RECRUITING Irinotecan Liposome for Resectable Pancreatic Cancer With or Without Addebelizumab
Zhejiang University
NCT06159478 RECRUITING Binimetinib in Patients With BRAF Fusion-positive Low-grade Glioma or Pancreatic Cancer (Perfume)
National Cancer Center, Japan
NCT06166589 NOT YET RECRUITING Second-line Zimberelimab and SIRIOX Chemotherapy for Patient With Previously AG Chemotherapy Treated Pancreatic Cancer
Shanghai Zhongshan Hospital
NCT05810792 NOT YET RECRUITING Histamine Dihydrochloride and Interleukin-2 in Primary Resectable Pancreatic Cancer
Sahlgrenska University Hospital
NCT05637567 NOT YET RECRUITING Perioperative Platelet Inhibition With Acetylsalicylic Acid in Patients With Resectable Tumors of the Pancreatic Head
German Cancer Research Center
NCT05988372 NOT YET RECRUITING Surufatinib and Serplulimab Combined With AG Regimen Compare With AG Regimen as Conversion Therapy for Patients With Locally Advanced Pancreatic Cancer (SAGE)
Sun Yat-sen University
NCT06051851 RECRUITING Penpulimab Combined With Anlotinib and Nab-paclitaxel Plus Gemcitabine as First-line Treatment for Advanced Metastatic Pancreatic Cancer
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
NCT06009029 NOT YET RECRUITING SBRT Combined With Zimberelimab (GLS-010) in Locally Advanced Pancreatic Cancer (SPARK-1 Study)
Peking University Third Hospital
NCT05083247 RECRUITING Preoperative mFOLFIRINOX (or Gem-Nab-P) +/- Isotoxic High-dose SBRT for Borderline Resectable Pancreatic Adenocarcinoma
Erasme University Hospital
NCT05733000 RECRUITING CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors
Northwestern University
NCT05679583 RECRUITING Preoperative Stereotactic Body Radiation Therapy in Patients With Resectable Pancreatic Cancer
Yonsei University
NCT04361162 ACTIVE NOT RECRUITING Nivolumab + Ipilimumab + Radiation in MSS Pancreatic Cancer
Massachusetts General Hospital
NCT03498326 RECRUITING Gemcitabine and Celecoxib Combination Therapy in Treating Patients With R0 Resection Pancreatic Cancer
Second Affiliated Hospital, School of Medicine, Zhejiang University
NCT07600268 RECRUITING Efficacy of Stereotactic Body Radiotherapy (SBRT) Combined With Maintenance Therapy Compared to Maintenance Therapy Alone in Advanced Pancreatic Cancer
Shandong Cancer Hospital and Institute
NCT07595835 RECRUITING CT-guided Percutaneous Radionuclide Therapy With 32P Microparticles in Patients With Non-progressive Locally Advanced Pancreatic Cancer
M.R. Meijerink
NCT07594626 NOT YET RECRUITING BMS-986504 in Combination With Pemetrexed for the Treatment of Metastatic Solid Tumors With MTAP Deletion
Northwestern University
NCT07595172 RECRUITING NALIRIFOX+Adebrelimab+PULSAR for Advanced Pancreatic Cancer
West China Hospital
NCT07589569 NOT YET RECRUITING An Open-label, Multicenter, Phase II Clinical Study to Evaluate HRS-7058 in Patients With Pancreatic Cancer
Shandong Suncadia Medicine Co., Ltd.
NCT07586813 RECRUITING Romiplostim N01 Plus ATRA for Persistent Isolated Chemotherapy-Induced Thrombocytopenia After Complete Remission of Gastrointestinal Solid Tumors
Peking University People's Hospital
NCT06119217 COMPLETED Phase 2 Study of TTX-030 and Chemotherapy With or Without Budigalimab for 1L mPDAC Patients
Trishula Therapeutics, Inc.
NCT03415854 COMPLETED Paclitaxel Protein Bound Plus Cisplatin Plus Gemcitabine and Paricalcitol for Pancreatic Adenocarcinoma (NABPLAGEMD)
HonorHealth Research Institute
NCT03767582 COMPLETED Trial of Neoadjuvant and Adjuvant Nivolumab and BMS-813160 With or Without GVAX for Locally Advanced Pancreatic Ductal Adenocarcinomas.
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT05415917 WITHDRAWN Adjuvant Gemcitabine and Capecitabine Chemotherapy in Resected Pancreatic Cancer Following Neoadjuvant Chemotherapy
Rutgers, The State University of New Jersey
NCT03797326 COMPLETED Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) in Previously Treated Participants With Select Solid Tumors (MK-7902-005/E7080-G000-224/LEAP-005)
Merck Sharp & Dohme LLC
NCT04481204 WITHDRAWN New and Emerging Therapies for the Treatment of Resectable, Borderline Resectable, or Locally Advanced Pancreatic Cancer, PIONEER-Panc Study
M.D. Anderson Cancer Center
NCT06390059 COMPLETED EF-39 PANOVA-4: Study of Tumor Treating Fields Concomitant With Atezolizumab, Gemcitabine and Nab-Paclitaxel as First-LineTreatment for Metastatic Pancreatic Ductal Adenocarcinoma
NovoCure Ltd.
NCT06630325 TERMINATED A Precision Medicine Approach (SMMART-ACT) for the Treatment of Patients With Advanced Sarcoma, Prostate, Breast, Ovarian or Pancreatic Cancer
OHSU Knight Cancer Institute
NCT05014776 COMPLETED Study of CRS-207, Pembrolizumab, Ipilimumab, and Tadalafil in Metastatic Pancreatic Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT03915444 COMPLETED Nab-Paclitaxel + Cisplatin + Gemcitabine in Untreated Metastatic Pancreatic Adenocarcinoma
HonorHealth Research Institute
NCT03138720 COMPLETED Pre-operative Treatment for Patients With Untreated Pancreatic Cancer
HonorHealth Research Institute
NCT04387071 TERMINATED CMP-001 and INCAGN01949 for Patients With Stage IV Pancreatic Cancer and Other Cancers Except Melanoma
University of Southern California
NCT05518110 TERMINATED PaTcH Study: A Phase 2 Study of Trametinib and Hydroxychloroquine in Patients With Metastatic Refractory Pancreatic Cancer
Cancer Trials Ireland
NCT02985125 COMPLETED LEE011 Plus Everolimus in Patients With Metastatic Pancreatic Adenocarcinoma Refractory to Chemotherapy
Georgetown University
NCT02077881 COMPLETED Study of IDO Inhibitor in Combination With Gemcitabine and Nab-Paclitaxel in Patients With Metastatic Pancreatic Cancer
NewLink Genetics Corporation
NCT05586516 COMPLETED A Study to Assess an ATX Inhibitor (IOA-289) in Patients With Metastatic Pancreatic Cancer
iOnctura
NCT03601923 COMPLETED Niraparib in Patients With Pancreatic Cancer
Dana-Farber Cancer Institute
NCT05039177 COMPLETED A Study of ERAS-007 in Patients With Advanced Gastrointestinal Malignancies
Erasca, Inc.
NCT06538623 COMPLETED Oxaliplatin Combined With Irinotecan Liposome Injection II Through Hepatic Artery Infusion (HAIC) Followed by 5-FU/LV (HAIC) or Tegorgor Oral Combination Therapy for Hepatic Metastasis of Pancreatic Cancer
Ruijin Hospital
NCT03745326 TERMINATED Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 Patients
National Cancer Institute (NCI)
NCT02648282 COMPLETED Study With CY, Pembrolizumab, GVAX Pancreas Vaccine, and SBRT in Patients With Locally Advanced Pancreatic Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT01204372 COMPLETED Trial Evaluating Combined Chemotherapy in Patients With Metastatic Pancreatic Adenocarcinoma
Institut du Cancer de Montpellier - Val d'Aurelle
NCT04332653 COMPLETED NT-I7 (Efineptakin Alfa) in Combination With Pembrolizumab in Participants With Advanced Solid Tumors
NeoImmuneTech
NCT02047474 COMPLETED Combination Chemotherapy Before and After Surgery in Treating Patients With Localized Pancreatic Cancer
Yale University
NCT04705818 COMPLETED Combining Epigenetic And Immune Therapy to Beat Cancer.
Institut Bergonié
NCT02890355 COMPLETED FOLFIRI or Modified FOLFIRI and Veliparib as Second Line Therapy in Treating Patients With Metastatic Pancreatic Cancer
National Cancer Institute (NCI)
NCT04975516 TERMINATED Standard of Care Chemotherapy With or Without Stereotactic Body Radiation Therapy for Oligometastatic Pancreatic Cancer
Mayo Clinic
NCT02705196 COMPLETED LOAd703 Oncolytic Virus Therapy for Pancreatic Cancer
Lokon Pharma AB
NCT05419479 SUSPENDED Switch Maintenance in Pancreatic
James Cleary, MD, PhD
NCT04426669 COMPLETED A Study of Metastatic Gastrointestinal Cancers Treated With Tumor Infiltrating Lymphocytes in Which the Gene Encoding the Intracellular Immune Checkpoint CISH Is Inhibited Using CRISPR Genetic Engineering
Intima Bioscience, Inc.
NCT03785210 TERMINATED Nivolumab (Anti-PD1), Tadalafil and Oral Vancomycin in People With Refractory Primary Hepatocellular Carcinoma or Liver Dominant Metastatic Cancer From Colorectal or Pancreatic Cancers
National Cancer Institute (NCI)
NCT04469556 COMPLETED Pancreatic Adenocarcinoma Signature Stratification for Treatment
University Health Network, Toronto
NCT05000294 SUSPENDED Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types
University of Florida
NCT05442749 TERMINATED Niraparib as First Line Therapy With Metastatic Homologous Repair-deficient Pancreatic Cancer
Centre Leon Berard
NCT03983057 COMPLETED Combination of Anti-PD-1 Antibody and Chemotherapy in Pancreatic Cancer
Zhejiang University
NCT03727880 COMPLETED Study of Pembrolizumab With or Without Defactinib Following Chemotherapy as a Neoadjuvant and Adjuvant Treatment for Resectable Pancreatic Ductal Adenocarcinoma
Lei Zheng
NCT04524702 COMPLETED Paricalcitol and Hydroxychloroquine in Combination With Gemcitabine and Nab-Paclitaxel for Advanced Pancreatic Cancer
Emory University
NCT05262855 COMPLETED Study of [68Ga]FAPI-46 PET in Patients With Pancreatic Ductal Carcinoma
SOFIE
NCT05641896 COMPLETED Study of [18F]FAPI-74 PET in Patients With Gastrointestinal Cancers
SOFIE
NCT05070247 TERMINATED A Study of TAK-500 With or Without Pembrolizumab in Adults With Select Locally Advanced or Metastatic Solid Tumors
Takeda
NCT06478862 TERMINATED Promitil Treatment of Patients With Solid Tumors Associated With Deleterious Mutations Who Have Progressed After Therapy
Lipomedix Pharmaceuticals Inc.
NCT04643405 TERMINATED APG-1387 Plus Chemotherapy in Advanced Pancreatic Adenocarcinoma
Ascentage Pharma Group Inc.
NCT03443492 COMPLETED SLOG vs mFOLFIRINOX as the First-line Treatment in Locally Advanced Uncresectable or Metastatic Pancreatic Cancer
National Health Research Institutes, Taiwan
NCT04752696 COMPLETED Onvansertib in Combination With Nanoliposomal Irinotecan, Leucovorin, and Fluorouracil for Second-Line Treatment of Participants With Metastatic Pancreatic Ductal Adenocarcinoma
Cardiff Oncology
NCT03910387 COMPLETED Telotristat Ethyl to Promote Weight Stability in Patients With Advanced Stage Pancreatic Cancer
Emory University
NCT05289830 TERMINATED Escitalopram to Placebo in Patients With Localized Pancreatic Cancer
Case Comprehensive Cancer Center
NCT05114213 TERMINATED MR-Guided Adaptive SBRT of Primary Tumor for Pain Control in Metastatic PDAC
Ludwig-Maximilians - University of Munich
NCT04779151 TERMINATED Basket Trial Exploring the Efficacy and Safety of the Combination of Niraparib and Dostarlimab
Gustave Roussy, Cancer Campus, Grand Paris
NCT05795595 COMPLETED A Safety and Efficacy Study Evaluating CTX131 in Adult Subjects With Relapsed or Refractory Solid Tumors
CRISPR Therapeutics AG
NCT03193190 COMPLETED A Study of Multiple Immunotherapy-Based Treatment Combinations in Participants With Metastatic Pancreatic Ductal Adenocarcinoma (Morpheus-Pancreatic Cancer)
Hoffmann-La Roche
NCT04054362 COMPLETED Paricalcitol Addition to Chemotherapy in Patients With Previously Untreated Metastatic Pancreatic Ductal Adenocarcinoma
Barts & The London NHS Trust
NCT05052723 COMPLETED Cabozantinib and Pembrolizumab in Metastatic Pancreas
Joseph Kim
NCT07026916 WITHDRAWN A Phase II Study to Evaluate GFH375 in Patients With KRAS G12D Mutant Metastatic Pancreatic Cancer
Genfleet Therapeutics (Shanghai) Inc.
NCT05525286 TERMINATED Clinical Trial of SOT102 Antibody Drug Conjugate in Patients With Advanced Gastric and Pancreatic Adenocarcinoma
SOTIO Biotech a.s.
NCT04844970 TERMINATED Anamorelin Study for Advanced Pancreatic Cancer
Lahey Clinic
NCT04504916 TERMINATED A Study of Zilovertamab Vedotin (MK-2140/VLS-101) in Participants With Solid Tumors (MK-2140-002)
VelosBio Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
NCT05194735 TERMINATED Phase I/II Study of Autologous T Cells to Express T-Cell Receptors (TCRs) in Subjects With Solid Tumors
Alaunos Therapeutics
NCT01489865 COMPLETED ABT-888 With Modified FOLFOX6 in Patients With Metastatic Pancreatic Cancer
Georgetown University
NCT06069778 TERMINATED Safety, Tolerability, and Efficacy of mFOLFIRINOX ± BNT321 as Adjuvant Therapy Following Curative Resection in Patients With Pancreatic Adenocarcinoma
BioNTech SE
NCT05169437 TERMINATED Niraparib in the Treatment of Patients With Advanced PALB2 Mutated Tumors
Tempus AI
NCT03192462 COMPLETED TAA Specific Cytotoxic T Lymphocytes in Patients With Pancreatic Cancer
Baylor College of Medicine
NCT04390763 TERMINATED Study of Efficacy and Safety of NIS793 (With and Without Spartalizumab) in Combination With SOC Chemotherapy in First-line Metastatic Pancreatic Ductal Adenocarcinoma (mPDAC)
Novartis Pharmaceuticals
NCT05494697 SUSPENDED Ampligen Combined With SOC Versus SOC Alone Following First-Line Therapy in Subjects With LAPC
AIM ImmunoTech Inc.
NCT03404960 COMPLETED Niraparib + Ipilimumab or Nivolumab in Progression Free Pancreatic Adenocarcinoma After Platinum-Based Chemotherapy
University of Pennsylvania
NCT03184870 COMPLETED A Study of BMS-813160 in Combination With Chemotherapy or Nivolumab in Participants With Advanced Solid Tumors
Bristol-Myers Squibb
NCT03417921 SUSPENDED A Study of ABTL0812 in Pancreatic Cancer
Ability Pharmaceuticals SL
NCT04257448 COMPLETED Safety and Tolerance of Epigenetic and Immunomodulating Drugs Combined With Chemotherapeutics in Patients Suffering From Advanced Pancreatic Cancer
GWT-TUD GmbH
NCT06690281 WITHDRAWN A Phase II Study of Adjuvant Immunotherapy Targeting KRAS G12D, KRAS G12V, or TP53 R175H for Participants With Advanced Gastrointestinal Malignancies
National Cancer Institute (NCI)
NCT00964171 COMPLETED Efavirenz as Second-Line Therapy in Treating Patients With Metastatic Pancreatic Cancer
Institut Bergonié
NCT02754726 COMPLETED Combination Therapy for Patients With Untreated Metastatic Pancreatic Ductal Adenocarcinoma
HonorHealth Research Institute
NCT04191421 COMPLETED Siltuximab and Spartalizumab in Patients With Metastatic Pancreatic Cancer
Emory University
NCT05259696 COMPLETED Glycan Mediated Immune Regulation With a Bi-Sialidase Fusion Protein (GLIMMER-01)
Palleon Pharmaceuticals, Inc.
NCT04409002 COMPLETED Niraparib + Dostarlimab + RT in Pancreatic Cancer
Massachusetts General Hospital
NCT04493060 COMPLETED Niraparib and Dostarlimab for the Treatment of Germline or Somatic BRCA1/2 and PALB2 Mutated Metastatic Pancreatic Cancer
Mayo Clinic
NCT03697564 COMPLETED Nivolumab + Cabiralizumab + Gemcitabine in Patients With Stage IV Pancreatic Cancer
Hitendra Patel
NCT03033225 COMPLETED Ultrasound-Guided Verteporfin Photodynamic Therapy for the Treatment of Unresectable Solid Pancreatic Tumors or Advanced Pancreatic Cancer, VERTPAC-02 Study
Mayo Clinic
NCT04116073 COMPLETED INCMGA00012 in Patients With Previously Treated Unresectable or Metastatic Adenosquamous Pancreatic or Ampullary Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT03496662 COMPLETED BMS-813160 With Nivolumab and Gemcitabine and Nab-paclitaxel in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma (PDAC)
Washington University School of Medicine
NCT01781728 COMPLETED Palliative Stereotactic Radiation for Pancreatic or Periampullary Adenocarcinoma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT01342354 COMPLETED Study of Stereotactic Body Radiation Therapy in Patients With Intact Pancreatic Cancer
University of Chicago
NCT05239182 TERMINATED 9-ING-41 Plus Retifanlimab and Gemcitabine/Nab-Paclitaxel in Patients With Advanced Pancreatic Adenocarcinoma
Anwaar Saeed
NCT04992507 TERMINATED Impact of Total Intravenous Anesthesia Following Cancer Surgery, TIVACS Study
Ohio State University Comprehensive Cancer Center
NCT05563272 TERMINATED 89Zr-girentuximab for PET Imaging of CAIX Positive Solid Tumors
Telix Pharmaceuticals (Innovations) Pty Ltd
NCT02611024 COMPLETED Pharmacokinetic Study of Lurbinectedin in Combination With Irinotecan in Patients With Selected Solid Tumors
PharmaMar
NCT02723331 COMPLETED Perioperative Therapy for Resectable and Borderline-Resectable Pancreatic Adenocarcinoma With Molecular Correlates
Academic Thoracic Oncology Medical Investigators Consortium
NCT03693677 COMPLETED First Line Metastatic Pancreatic Cancer : 5FU/LV+Nal-IRI, Gemcitabine+Nab-paclitaxel or a Sequential Regimen of 2 Months 5FU/LV+Nal-IRI
Federation Francophone de Cancerologie Digestive
NCT06592664 WITHDRAWN Certepetide Phase 1b/2a Continuous Infusion Trial in mPDAC
Lisata Therapeutics, Inc.
NCT05546476 COMPLETED Study of the Efficacy and Safety of Ponsegromab in Patients With Cancer, Cachexia and Elevated GDF-15
Pfizer
NCT04068896 COMPLETED Study of NGM120 in Subjects With Advanced Solid Tumors, Pancreatic Cancer, and Prostate Cancer Using Combination Therapy
NGM Biopharmaceuticals, Inc
NCT03250273 COMPLETED A Clinical Trial of Entinostat in Combination With Nivolumab for Patients With Previously Treated Unresectable or Metastatic Cholangiocarcinoma and Pancreatic Adenocarcinoma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT06241352 COMPLETED Statin Addition to Chemotherapy for Advanced Pancreatic Cancer
Changhai Hospital
NCT01144455 COMPLETED Study of the Safety and Efficacy of TH-302 in Combination With Gemcitabine Compared With Gemcitabine Alone in Previously Untreated Patients With Pancreatic Adenocarcinoma
ImmunoGenesis
NCT01834235 TERMINATED QUILT-3.010: A Study of Gemcitabine and Nab-paclitaxel With or Without NPC-1C to Treat Patients With Pancreatic Cancer
Precision Biologics, Inc
NCT05251233 TERMINATED Role of Proton Pump Inhibitors on the Postoperative Course Following Pancreaticoduodenectomy
Washington University School of Medicine
NCT01555489 TERMINATED Assessing the Efficacy and Safety of IV Vitamin C in Combination With Standard Chemotherapy for Pancreatic Ca
Thomas Jefferson University
NCT02632448 COMPLETED A Study of LY2880070 in Participants With Advanced or Metastatic Cancer
Esperas Pharma Inc.
NCT00640978 TERMINATED Erlotinib and RAD001 (Everolimus) in Patients With Previously Treated Advanced Pancreatic Cancer
M.D. Anderson Cancer Center
NCT03374852 WITHDRAWN CPI-613 in Combination With Modified FOLFIRINOX in Patients With Locally Advanced Pancreatic Cancer
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
NCT03610490 TERMINATED Autologous Tumor Infiltrating Lymphocytes MDA-TIL in Treating Patients With Recurrent or Refractory Ovarian Cancer, Colorectal Cancer, or Pancreatic Ductal Adenocarcinoma
M.D. Anderson Cancer Center
NCT05673811 COMPLETED Study of Nab-Paclitaxel and Gemcitabine and Plus/Minus VCN-01 in Patients With Metastatic Pancreatic Cancer
Theriva Biologics SL
NCT04383210 TERMINATED Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors
Elevation Oncology
NCT03829501 TERMINATED A Phase 1/2, Open-label, Multi-center Study of the Safety and Efficacy of Alomfilimab (KY1044) as Single Agent and in Combination With Anti-PD-L1 (Atezolizumab) in Adult Patients With Selected Advanced Malignancies
Kymab Limited
NCT02650804 COMPLETED BPM31510 Administered Intravenously With Gemcitabine in Advanced Pancreatic Cancer Patients
BPGbio
NCT06111872 COMPLETED Ketamine-midazolam as a Sedative Agent in Endoscopic Retrograde Cholangiopancreatography.
National University of Malaysia
NCT05360264 TERMINATED tailOred dRug repurposIng of dEcitabine in KRAS-dependeNt refracTory pAncreaTic cancEr
Luca Cardone
NCT02879318 COMPLETED Gemcitabine and Nab-Paclitaxel vs Gemcitabine, Nab-Paclitaxel, Durvalumab and Tremelimumab as 1st Line Therapy in Metastatic Pancreatic Adenocarcinoma
Canadian Cancer Trials Group
NCT04976660 WITHDRAWN TT-4 As a Single Agent in Subjects with Advanced Selected Solid Tumors
Tarus Therapeutics, Inc.
NCT01601808 COMPLETED Clinical Trial Comparing Gemcitabine and Vandetanib Therapy With Gemcitabine Alone in Pancreatic Carcinoma
University of Liverpool
NCT04247165 COMPLETED Nivolumab, Ipilimumab and Chemoradiation in Pancreatic Cancer.
Herlev Hospital
NCT03058289 COMPLETED A Phase 1/2 Safety Study of Intratumorally Dosed INT230-6
Intensity Therapeutics, Inc.
NCT03563144 WITHDRAWN QUILT-3.088: NANT Pancreatic Cancer Vaccine
ImmunityBio, Inc.
NCT02907099 COMPLETED Pembrolizumab and CXCR4 Antagonist BL-8040 in Treating Patients With Metastatic Pancreatic Cancer
M.D. Anderson Cancer Center
NCT03822936 TERMINATED Carbon Ions Radiation Therapy for Resectable or Borderline Resectable Pancreas Adenocarcinoma
CNAO National Center of Oncological Hadrontherapy
NCT04386057 COMPLETED LY3214996 +/- HCQ in Pancreatic Cancer
Kimberly Perez, MD
NCT04666688 COMPLETED LYT-200 Alone and in Combination With Chemotherapy or Tislelizumab in Patients With Locally Advanced or Metastatic Solid Tumors
PureTech
NCT03161379 COMPLETED GVAX Pancreas Vaccine (With CY) in Combination With Nivolumab and SBRT for Patients With Borderline Resectable Pancreatic Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT04662112 COMPLETED Liposomal Irinotecan, S-1, and Oxaliplatin in Advanced Pancreatic Adenocarcinoma
Asan Medical Center
NCT03699319 COMPLETED CPI-613 in Combination With Modified FOLFIRINOX in Locally Advanced Pancreatic Cancer
David Bajor, MD
NCT05031494 COMPLETED A Study to Assess YH003 in Combination with Toripalimab(anti-PD-1 MAb) Injection in Patients with Cancers
Eucure (Beijing) Biopharma Co., Ltd
NCT02581215 COMPLETED Phase II Randomized Trial of mFOLFIRINOX +/- Ramucirumab in Advanced Pancreatic Cancer
Walid Shaib, MD
NCT05861336 WITHDRAWN GEM+Nab-Paclitaxel Plus Losartan Followed by Stereotactic Radiotherapy for Locally Advanced Pancreatic Cancer
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
NCT03974854 TERMINATED Evaluation of Polychemotherapy With XELOXIRI-3 in Elderly or Frail Patients With Advanced Pancreatic Adenocarcinoma
Centre Hospitalier Universitaire de Besancon
NCT04731467 COMPLETED A Study of CM24 in Combination with Nivolumab in Adults with Advanced Solid Tumors
Famewave Ltd.
NCT03997968 COMPLETED A Phase 1/2 Study of CYT-0851 in B-Cell Malignancies and Advanced Solid Tumors
Cyteir Therapeutics, Inc.
NCT05546411 TERMINATED A Trial of NIS793 With FOLFIRINOX in Pancreatic Cancer
Kimberly Perez, MD
NCT03329248 TERMINATED QUILT-3.060: NANT Pancreatic Cancer Vaccine: Molecularly Informed Integrated Immunotherapy in Subjects With Pancreatic Cancer Who Have Progressed on or After Standard-of-care Therapy
ImmunityBio, Inc.
NCT01905150 COMPLETED Ph 2 Trial of Vitamin C & G-FLIP (Low Doses Gemcitabine, 5FU, Leucovorin, Irinotecan, Oxaliplatin) for Pancreatic Cancer
Bruckner Oncology
NCT03225989 COMPLETED Trial Investigating an Immunostimulatory Oncolytic Adenovirus for Cancer
Lokon Pharma AB
NCT01064622 COMPLETED Gemcitabine Hydrochloride With or Without Vismodegib in Treating Patients With Recurrent or Metastatic Pancreatic Cancer
National Cancer Institute (NCI)
NCT03592264 TERMINATED A Phase I/II Study of OBI-3424 in Subjects with Advanced Solid Tumors
OBI Pharma, Inc
NCT03207867 TERMINATED A Phase 2 Study of NIR178 in Combination With PDR001 in Patients With Solid Tumors and Non-Hodgkin Lymphoma
Novartis Pharmaceuticals
NCT03006302 COMPLETED Epacadostat, Pembrolizumab, and CRS-207, With or Without CY/GVAX Pancreas in Patients With Metastatic Pancreas Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT04536077 TERMINATED Immunologic Effects of CDX-301 and CDX-1140 in Resectable Pancreatic Cancer Patients
Washington University School of Medicine
NCT04683939 TERMINATED Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT141 in Patients With Unresectable or Metastatic CLDN18.2-positive Gastric, Pancreatic, Ovarian and Biliary Tract Tumors
BioNTech SE
NCT02677038 COMPLETED Olaparib in Treating Patients With Stage IV Pancreatic Cancer
M.D. Anderson Cancer Center
NCT04098432 COMPLETED STR + Anti PD-1 Therapy in Patients with Locally Advanced Unresectable Pancreatic Adenocarcinoma
University Hospital Hradec Kralove
NCT04156087 COMPLETED Progression-free Survival After MWA Plus Durvalumab and Tremelimumab for Unresectable Locally Advanced Pancreatic Cancer
Baki Topal
NCT02745197 WITHDRAWN A Study to See Whether a Nutritional Supplement is Beneficial for Patients With Pancreatic Cancer
University of Alberta
NCT05052567 COMPLETED CEND-1 Injection (QLC12102) in Patients With Advanced Metastatic Pancreatic Ductal Adenocarcinoma
Qilu Pharmaceutical Co., Ltd.
NCT02826486 COMPLETED Study Assessing Safety and Efficacy of Combination of BL-8040 and Pembrolizumab in Metastatic Pancreatic Cancer Patients
BioLineRx, Ltd.
NCT02431676 COMPLETED Survivorship Promotion In Reducing IGF-1 Trial
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT03586869 TERMINATED QUILT-3.080: NANT Pancreatic Cancer Vaccine
ImmunityBio, Inc.
NCT03486327 TERMINATED Transabdominal Ultrasound With BR55 for Characterization of Pancreatic Lesions
Bracco Diagnostics, Inc
NCT03267316 COMPLETED A First-in-Human Study of CAN04 in Patients With Solid Malignant Tumors
Cantargia AB
NCT00819169 TERMINATED QUILT-3.026: AMG 655 in Combination With AMG 479 in Advanced, Refractory Solid Tumors
NantCell, Inc.
NCT04228601 COMPLETED A Study of Fluzoparib in Combination With mFOLFIRINOX in Patients With Advanced Pancreatic Cancer
Jiangsu HengRui Medicine Co., Ltd.
NCT06518538 WITHDRAWN Evaluate Efficacy of Devimistat in Combination With mFFX in 2nd Line Patients With Metastatic Pancreatic Cancer
Cornerstone Pharmaceuticals
NCT01595321 COMPLETED Pancreatic Tumor Cell Vaccine (GVAX), Cyclophosphamide, SBRT, and FOLFIRINOX in Patients With Resected Adenocarcinoma of the Pancreas
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT03190265 COMPLETED Study of CRS-207, Nivolumab, and Ipilimumab With or Without GVAX Pancreas Vaccine (With Cy) in Patients With Pancreatic Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT03127098 TERMINATED QUILT-3.040: ETBX-011 (Ad5 [E1-, E2b-]-CEA(6D)) Vaccine in Combination With ALT-803 (Super-agonist IL-15) in Subjects Having CEA-Expressing Cancer
NantCell, Inc.
NCT02697058 COMPLETED Phase II of BAX2398/5-FU/Calcium Levofolinate in Pancreatic Cancer
Institut de Recherches Internationales Servier
NCT03336216 COMPLETED A Study of Cabiralizumab Given With Nivolumab With and Without Chemotherapy in Patients With Advanced Pancreatic Cancer
Bristol-Myers Squibb
NCT06398587 WITHDRAWN Onvansertib in Combination With Gemcitabine and Nab-paclitaxel for the Treatment of Patients With Locally-advanced, Unresectable, or Metastatic Pancreatic Ductal Adenocarcinoma
OHSU Knight Cancer Institute
NCT02352337 COMPLETED First-line Metastatic Pancreatic Cancer : FOLFIRINOX +/- LV5FU2 in Maintenance Versus Firgem
Federation Francophone de Cancerologie Digestive
NCT02827201 COMPLETED FIrst Line Treatment of Metastatic Pancreatic Cancer: Sequential Nab-paclitaxel + Gemcitabine/FOLFIRI.3 VS Nab-paclitaxel + Gemcitabine
Federation Francophone de Cancerologie Digestive
NCT03077685 COMPLETED Trial of NanoPac® in Subjects With Locally Advanced Pancreatic Adenocarcinoma
NanOlogy, LLC
NCT03136406 TERMINATED QUILT-3.039: NANT Pancreatic Cancer Vaccine: Combination Immunotherapy in Subjects With Pancreatic Cancer Who Have Progressed on or After Standard-of-care Therapy
ImmunityBio, Inc.
NCT01580397 COMPLETED Pilot Phase 2 Study to Investigate the Preliminary Efficacy and Safety of INNO-206 in Advanced Pancreatic Cancer
ImmunityBio, Inc.
NCT05116917 TERMINATED Immunotherapy Combined With Radiation and Influenza Vaccine for Pancreatic Cancer.
Herlev Hospital
NCT03450018 TERMINATED A Study of SLC-0111 and Gemcitabine for Metastatic Pancreatic Ductal Cancer in Subjects Positive for CAIX
British Columbia Cancer Agency
NCT03387098 TERMINATED QUILT-3.070:Pancreatic Cancer Vaccine: Subjects With Pancreatic Cancer Who Have Progressed on or After Standard-of-care Therapy
ImmunityBio, Inc.
NCT04698915 TERMINATED Phase 2b Study of GC4711 in Combination With SBRT for Nonmetastatic Pancreatic Cancer
Galera Therapeutics, Inc.
NCT04090463 SUSPENDED IORT on Borderline Resectable Pancreatic Cancer
Universita di Verona
NCT04390243 TERMINATED Binimetinib and Encorafenib for the Treatment of Pancreatic Cancer in Patients With a Somatic BRAF V600E Mutation
Academic and Community Cancer Research United
NCT03146962 COMPLETED High Dose Vitamin C Intravenous Infusion in Patients With Resectable or Metastatic Solid Tumor Malignancies
Weill Medical College of Cornell University
NCT04808362 TERMINATED Phase 1/2 Study to Evaluate Safety, PK and Efficacy of the MYC-Inhibitor OMO-103 in Solid Tumours
Peptomyc S.L.
NCT03848182 TERMINATED Analyzing Childhood Recall Antigens in Patients With Pancreatic Cancer
Albert Einstein College of Medicine
NCT03127124 WITHDRAWN QUILT-2.022 NANT-008 in Combination w/ 5-fluorouracil, Bevacizumab, Leucovorin & Oxaliplatin in Subjects With Pancreatic Cancer
NantPharma, LLC
NCT04431258 COMPLETED ABTL0812 in Combination With FOLFIRINOX for First-line Treatment of Metastatic Pancreatic Study
Ability Pharmaceuticals SL
NCT04617067 COMPLETED Paricalcitol Trial: Phase II, Open Label Clinical Trial of Paricalcitol in Combination With Gemcitabine/ Nab-Paclitaxel Therapy in Advanced Pancreatic Cancer
Cancer Trials Ireland
NCT02128100 COMPLETED Effects of Folfirinox and Stereotactic Body Radiation Therapy for Advanced Pancreatic Cancer
University of Louisville
NCT06278493 COMPLETED A Clinical Study of AL2846 Capsule Combined With Gemzar Injection in the Treatment of Advanced Pancreatic Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT04177810 COMPLETED Plerixafor and Cemiplimab in Metastatic Pancreatic Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT01959139 COMPLETED S1313, PEGPH20 in Treating Patients With Newly Diagnosed Metastatic Pancreatic Cancer
SWOG Cancer Research Network
NCT01525082 COMPLETED Capecitabine, Temozolomide, and Bevacizumab for Metastatic or Unresectable Pancreatic Neuroendocrine Tumors
Shaheen Shagufta
NCT03376659 TERMINATED Durvalumab Plus CV301 With Maintenance Chemotherapy in Metastatic Colorectal or Pancreatic Adenocarcinoma
Georgetown University
NCT04624217 COMPLETED A Trial of SHR-1701 in Combination With Gemcitabine and Albumin Paclitaxel in Patients With Pancreatic Cancer
Jiangsu HengRui Medicine Co., Ltd.
NCT03340974 COMPLETED Pilot Dose Escalation Trial of Stereotactic Body Radiation Therapy (SBRT) in Combination With GC4419 in Pancreatic Cancer
Galera Therapeutics, Inc.
NCT03189914 COMPLETED RX-3117 in Combination With Abraxane® in Subjects With Metastatic Pancreatic Cancer
Processa Pharmaceuticals
NCT01897454 TERMINATED Gemcitabine Hydrochloride, and Radiation Therapy in Patients With Borderline Resectable Pancreatic Cancer
Albert Einstein College of Medicine
NCT04637698 TERMINATED OH2 Oncolytic Viral Therapy in Pancreatic Cancer
Binhui Biopharmaceutical Co., Ltd.
NCT02527434 COMPLETED Study of Tremelimumab in Patients With Advanced Solid Tumors
AstraZeneca
NCT04565327 TERMINATED Hyperpolarized 13C Pyruvate MRI for Treatment Response Assessment in Pancreatic Ductal Adenocarcinoma
Zhen Wang, MD
NCT02178436 COMPLETED Gemcitabine, Nab-paclitaxel and KPT-330 in Advanced Pancreatic Cancer
Mohammed Najeeb Al Hallak
NCT00625586 TERMINATED Monoclonal Antibody RAV12 and Gemcitabine in Treating Patients With Metastatic Pancreatic Cancer
MacroGenics
NCT04983407 TERMINATED Safety and Efficacy Study of AVB-S6-500 (Batiraxcept) in Patients With Advanced Pancreatic Adenocarcinoma
Aravive, Inc.
NCT02383433 TERMINATED Regorafenib Plus Gemcitabine in Metastatic Pancreatic Cancer
Case Comprehensive Cancer Center
NCT03714555 TERMINATED Disulfiram-Copper Gluconate in Met Pancreas Cancer w Rising CA19-9 on Abraxane-Gemzar, FOLFIRINOX or Gemcitabine
HonorHealth Research Institute
NCT03117920 COMPLETED A Phase II, International Open Label Trial of Minnelide™ in Patients With Refractory Pancreatic Cancer
Minneamrita Therapeutics LLC
NCT01959672 COMPLETED Chemotherapy, Stereotactic Body Radiation Therapy & Nelfinavir Mesylate in Locally Advanced Pancreatic Cancer
University of Nebraska
NCT02504333 COMPLETED Phase I/II Study of Nab-paclitaxel and Gemcitabine Followed by AG-mFOLFOX in Patients With Metastatic Pancreatic Adenocarcinoma
Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)
NCT03611556 COMPLETED MEDI9447(Oleclumab) Pancreatic Chemotherapy Combination Study.
MedImmune LLC
NCT05906615 COMPLETED Intravenous Lidocaine for Pain Associated With Pancreatic Cancer and Chronic Pancreatitis
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
NCT03140670 TERMINATED Maintenance Rucaparib in BRCA1, BRCA2 or PALB2 Mutated Pancreatic Cancer That Has Not Progressed on Platinum-based Therapy
Abramson Cancer Center at Penn Medicine
NCT02866383 COMPLETED Immune Checkpoint Inhibition in Combination With Radiation Therapy in Pancreatic Cancer or Biliary Tract Cancer Patients
Herlev Hospital
NCT03953235 COMPLETED A Study of a Personalized Cancer Vaccine Targeting Shared Neoantigens
Gritstone bio, Inc.
NCT02427841 COMPLETED Nab-paclitaxel and Gemcitabine Hydrochloride Followed by Radiation Therapy Before Surgery in Treating Patients With Pancreatic Cancer That Can Be Removed by Surgery
OHSU Knight Cancer Institute
NCT01470417 COMPLETED Gemcitabine With Abraxane and Other Investigational Therapies in Neoadjuvant Treatment of Pancreatic Adenocarcinoma
University of Florida
NCT04953962 COMPLETED Study of CBP501/Cisplatin/Nivolumab Combinations in Advanced Pancreatic Cancer
CanBas Co. Ltd.
NCT01726582 COMPLETED Pancreas Cancer: Molecular Profiling as a Guide to Therapy Before and After Surgery ("Personalized Medicine")
Medical College of Wisconsin
NCT03602079 COMPLETED Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene
Klus Pharma Inc.
NCT05926206 WITHDRAWN Trial of Devimistat in Combination With Modified FOLFIRINOX in Patients With Metastatic Adenocarcinoma of the Pancreas
University of Michigan Rogel Cancer Center
NCT03576131 TERMINATED GEN1029 (HexaBody®-DR5/DR5) Safety Trial in Patients With Malignant Solid Tumors
Genmab
NCT02324543 COMPLETED Study of Gemcitabine/Taxotere/Xeloda (GTX) in Combination With Cisplatin and Irinotecan in Subjects With Metastatic Pancreatic Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT00965718 COMPLETED Evaluate the Efficacy and Safety of Activated T-lymphocyte Cell Therapy in Advanced Pancreatic Cancer
GC Cell Corporation
NCT04212026 TERMINATED Irreversible Electroporation (IRE) Followed by Nivolumab in Patients With Metastatic Pancreatic Cancer.
University Hospital, Basel, Switzerland
NCT02775695 COMPLETED Efficacy of Doxycycline on Metakaryote Cell Death in Patients With Resectable Pancreatic Cancer
Medical College of Wisconsin
NCT02047513 COMPLETED Neoadjuvant Plus Adjuvant or Only Adjuvant Nab- Paclitaxel Plus Gemcitabine for Resectable Pancreatic Cancer
AIO-Studien-gGmbH
NCT02042378 COMPLETED A Study of Rucaparib in Patients With Pancreatic Cancer and a Known Deleterious BRCA Mutation
pharmaand GmbH
NCT03745430 COMPLETED RAmucirumab Combined wIth Standard Nab-paclitaxel and Gemcitabine as First-line Chemotherapy in Patients With Advanced Pancreatic Adenocarcinoma
Hellenic Cooperative Oncology Group
NCT02620865 COMPLETED BATS With in Combination With Low Dose IL-1 and GM-CSF for Advanced Pancreatic Cancer
Barbara Ann Karmanos Cancer Institute
NCT01845337 COMPLETED Study to Compare Cardiovascular Side Effects of Teysuno Versus Capecitabine
University of Edinburgh
NCT05251038 WITHDRAWN Study of Sotorasib Combined With Chemotherapy for Second Line Treatment of Pancreas Cancer
Devalingam Mahalingam
NCT02578732 COMPLETED FOLFOX-A For Locally Advanced Pancreatic Cancer: A Phase II Brown University Oncology Research Group Trial
Brown University
NCT02194829 COMPLETED Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Gemcitabine Hydrochloride With or Without WEE1 Inhibitor AZD1775 in Treating Patients With Previously Untreated Pancreatic Cancer That Is Metastatic or Cannot Be Removed by Surgery
National Cancer Institute (NCI)
NCT02511223 COMPLETED Efficacy and Safety of PARPi to Treat Pancreatic Cancer
Sheba Medical Center
NCT03410030 COMPLETED Trial of Ascorbic Acid (AA) + Nanoparticle Paclitaxel Protein Bound + Cisplatin + Gemcitabine (AA NABPLAGEM)
HonorHealth Research Institute
NCT02806687 COMPLETED Effect of Intratumoral Injection of Gene Therapy for Locally Advanced Pancreatic Cancer
University Hospital, Toulouse
NCT03717298 COMPLETED Evaluation of Ocoxin-Viusid® in Advanced Pancreatic Adenocarcinoma
Catalysis SL
NCT03801915 COMPLETED Perioperative MVT-5873, a Fully Human Monoclonal Antibody Against a CA 19-9 Epitope, for Operable CA 19-9 Producing Pancreatic Cancers, Cholangiocarcinomas, and Metastatic Colorectal Cancers
National Cancer Institute (NCI)
NCT02707159 COMPLETED Circulating Tumor Cells as Tools for Therapy Response in Nab-paclitaxel Treated Metastatic Pancreatic Cancer Patients
Helse Stavanger HF
NCT02210559 COMPLETED A Study of Gemcitabine Plus Nab-paclitaxel With or Without FG-3019 in Participants With Locally Advanced, Unresectable Pancreatic Cancer
Kyntra Bio
NCT02028806 COMPLETED mFOLFIRINOX as First-Line Chemotherapy in Treating Chinese Patients With Metastatic Pancreatic Cancer
Yuhong Li
NCT02426281 COMPLETED Nab-pacliatxel Plus Gemcitabine in Korean Patients With Metastatic Pancreatic Ductal Adenocarcinoma
Samsung Medical Center
NCT04224402 COMPLETED Efficacy and Safety of mFOLFIRINOX as Postoperative Chemotherapy for Pancreatic Cancer in Chinese Patients.
Yuhong Li
NCT01647828 COMPLETED A Phase 1b/2 Study of OMP-59R5 (Tarextumab) in Combination With Nab-Paclitaxel and Gemcitabine in Subjects With Previously Untreated Stage IV Pancreatic Cancer
OncoMed Pharmaceuticals, Inc.
NCT03977272 COMPLETED Combination of Anti-PD-1 Antibody and Chemotherapy in Metastatic Pancreatic Cancer
Zhejiang University
NCT02713529 COMPLETED Safety and Efficacy Study of AMG 820 and Pembrolizumab Combination in Select Advanced Solid Tumor Cancer
AmMax Bio, Inc.
NCT03331562 COMPLETED A SU2C Catalyst® Trial of a PD1 Inhibitor With or Without a Vitamin D Analog for the Maintenance of Pancreatic Cancer
Translational Genomics Research Institute
NCT03214250 COMPLETED Safety and Efficacy of APX005M With Gemcitabine and Nab-Paclitaxel With or Without Nivolumab in Patients With Previously Untreated Metastatic Pancreatic Adenocarcinoma
Parker Institute for Cancer Immunotherapy
NCT01939665 COMPLETED PANFIRE Study: Irreversible Electroporation (IRE) to Treat Locally Advanced Pancreatic Carcinoma
Amsterdam UMC, location VUmc
NCT02564146 COMPLETED First-line Treatment of Metastatic Pancreatic Cancer With Nab-paclitaxel and Gemcitabine
AIO-Studien-gGmbH
NCT03318497 COMPLETED Role of Interim 18F-FLT PET/CT for Outcome Prediction in Pancreatic Adenocarcinoma
University of Texas Southwestern Medical Center
NCT02428270 COMPLETED A Study of GSK2256098 and Trametinib in Advanced Pancreatic Cancer
University Health Network, Toronto
NCT03099265 TERMINATED Neoadjuvant Modified FOLFIRINOX and Stereotactic Body Radiation Therapy in Borderline Resectable Pancreatic Adenocarcinoma
Yale University
NCT02562716 COMPLETED S1505: Combination Chemotherapy or Gemcitabine Hydrochloride and Paclitaxel Albumin-Stabilized Nanoparticle Formulation Before Surgery in Treating Patients With Pancreatic Cancer That Can Be Removed by Surgery
SWOG Cancer Research Network
NCT02551991 COMPLETED Study of Nanoliposomal Irinotecan (Nal-IRI)-Containing Regimens Versus Nab-paclitaxel Plus Gemcitabine in Patients With Previously Untreated, Metastatic Pancreatic Adenocarcinoma
Ipsen
NCT03723915 TERMINATED Pembrolizumab and Pelareorep in Treating Patients With Advanced Pancreatic Cancer
Northwestern University
NCT01845805 COMPLETED Trial to Improve Outcomes in Patients With Resected Pancreatic Cancer (Azacitidine)
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT03158779 COMPLETED Evaluation of SBRT for Patients With Locally Advanced Unresectable Pancreatic Cancer
Istituto Clinico Humanitas
NCT01547260 COMPLETED Lenalidomide and Gemcitabine as First-line Treatment in Patients With Pancreatic Cancer
Maria Liljefors
NCT04769414 COMPLETED Flouro-Gem in Adenocarcinoma of the Pancreas (GEFLUPAN)
Menoufia University
NCT02080221 COMPLETED BrUOG 292: FOLFOX-A For Metastatic Pancreatic Cancer: A Phase II Brown University Oncology Research Group Trial
Brown University
NCT03559348 COMPLETED Locally Advanced or Metastatic Pancreatic Adenocarcinoma
National Health Research Institutes, Taiwan
NCT03086369 COMPLETED A Study of Nab-Paclitaxel and Gemcitabine With or Without Olaratumab (LY3012207) in Participants With Metastatic Pancreatic Cancer
Eli Lilly and Company
NCT05212025 WITHDRAWN Adavosertib and Gemcitabine in Advanced Pancreatic
James Cleary, MD, PhD
NCT01461915 TERMINATED Phase 2 Study to Assess the Efficacy & Safety of Gemcitabine + Nab Paclitaxel With or Without Dociparstat in Metastatic Pancreatic Cancer Patients
Jazz Pharmaceuticals
NCT02022033 COMPLETED BrUOG 295: Adjuvant FOLFOX-A For Resected Pancreatic Cancer: A Phase II Brown University Oncology Research Group Trial
Brown University
NCT04327986 TERMINATED Immune Checkpoint Inhibitor M7824 and the Immunocytokine M9241 in Combination With Stereotactic Body Radiation Therapy (SBRT) in Adults With Advanced Pancreas Cancer
National Cancer Institute (NCI)
NCT02704156 COMPLETED SBRT Plus Pembrolizumab and Trametinib for Pancreatic Cancer
Changhai Hospital
NCT02850874 WITHDRAWN HIPEC as Neoadjuvant Treatment for Resectable Pancreatic Adenocarcinoma
Wake Forest University Health Sciences
NCT02080260 COMPLETED A Study of Regorafenib in Advanced Pancreatic Cancer Patients
Wake Forest University Health Sciences
NCT02178709 COMPLETED A Phase II Study of Neoadjuvant FOLFIRINOX
Indiana University
NCT04258150 TERMINATED Ipilimumab, Nivolumab, Tocilizumab and Radiation in Pretreated Patients With Advanced Pancreatic Cancer
Herlev Hospital
NCT01360593 COMPLETED Gemcitabine/Capecitabine Followed by SBRT in Pancreatic Adenocarcinoma
David A. Clump, MD, PhD
NCT02131493 COMPLETED S-1 and and Gemcitabine vs Gemcitabine Alone as Adjuvant Chemotherapy for Patients With Resected Pancreatic Cancer
Zhejiang University
NCT00617708 COMPLETED S0727 Gemcitabine Hydrochloride and Erlotinib Hydrochloride With or Without Monoclonal Antibody Therapy in Treating Patients With Metastatic Pancreatic Cancer That Cannot Be Removed By Surgery
National Cancer Institute (NCI)
NCT03637491 TERMINATED A Study of Avelumab, Binimetinib and Talazoparib in Patients With Locally Advanced or Metastatic RAS-mutant Solid Tumors
Pfizer
NCT04790695 COMPLETED Single Patient Protocol for an NRG1 Fusion Positive Metastatic Pancreatic Cancer Patient Using Seribantumab
Ottawa Hospital Research Institute
NCT03331640 TERMINATED A Health Service Research Study to Investigate Survival of Metastatic Pancreatic Cancer Patients After Sequential Chemotherapy
AIO-Studien-gGmbH
NCT04105062 WITHDRAWN LS301 Uptake in Tumors of Patients Undergoing Liver, Pancreas, or Gastric Surgery
Washington University School of Medicine
NCT04070313 TERMINATED A Phase II Study of S-1 Adjuvant Chemotherapy in Patients With Resected Pancreatic Cancer in Taiwan
TTY Biopharm
NCT01303172 COMPLETED A Trial Comparing Gemcitabine With and Without IMM-101 in Advanced Pancreatic Cancer
Immodulon Therapeutics Ltd
NCT01660711 COMPLETED A Pilot Study of Pre- and Post-surgery Chemotherapy With mFOLFIRINOX in Localized, Resectable Pancreatic Adenocarcinoma
Endeavor Health
NCT03023722 COMPLETED Phase II Anetumab Ravtansine in Pre-treated Mesothelin-expressing Pancreatic Cancer
Yale University
NCT03599362 TERMINATED Study of Nivolumab, Cabiralizumab, and Stereotactic Body Radiotherapy (SBRT) for Locally Advanced Unresectable Pancreatic Cancer
NYU Langone Health
NCT03261947 COMPLETED A Study to Evaluate the Safety, Tolerability, and Activity of TAK-931 in Participants With Metastatic Pancreatic Cancer, Metastatic Colorectal Cancer, and Other Advanced Solid Tumors
Millennium Pharmaceuticals, Inc.
NCT00603863 COMPLETED Safety and Efficacy Study of Different Doses of 90Y-hPAM4 Combined With Gemcitabine in Pancreatic Cancer
Gilead Sciences
NCT01631552 COMPLETED Study of Sacituzumab Govitecan-hziy (IMMU-132) in Adults With Epithelial Cancer
Gilead Sciences
NCT01666730 COMPLETED Metformin Plus Modified FOLFOX 6 in Metastatic Pancreatic Cancer
Case Comprehensive Cancer Center
NCT03451773 TERMINATED M7824 (MSB0011359C) in Combination With Gemcitabine in Adults With Previously Treated Advanced Adenocarcinoma of the Pancreas
National Cancer Institute (NCI)
NCT01459614 COMPLETED Gemcitabine/Taxotere/Xeloda (GTX) With Cisplatin in Subjects With Metastatic Pancreatic Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT01053013 COMPLETED Open-Label Phase 2 Efficacy Trial of Cancer Macrobeads in Patients With Treatment-Resistant Pancreatic/Colorectal Cancer
The Rogosin Institute
NCT04464967 WITHDRAWN Safety and Preliminary Efficacy of SNK01 in Combination With Trastuzumab or Cetuximab in Subjects With Advanced HER2 or EGFR Cancers
NKGen Biotech, Inc.
NCT02562898 COMPLETED Ibrutinib Combined With Gemcitabine and Nab-Paclitaxel in Patients With Metastatic Pancreatic Cancer
Margaret Tempero
NCT01210911 COMPLETED Metformin Combined With Chemotherapy for Pancreatic Cancer
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
NCT01077986 COMPLETED Everolimus, Cetuximab and Capecitabine in Patients With Metastatic Pancreatic Cancer
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
NCT02311361 COMPLETED Immune Checkpoint Inhibition (Tremelimumab and/or MEDI4736) in Combination With Radiation Therapy in Patients With Unresectable Pancreatic Cancer
National Cancer Institute (NCI)
NCT02985801 TERMINATED PERT for Treatment of Exocrine Pancreatic Insufficiency in Patients With Unresectable Pancreatic Cancer
Massimo Raimondo, M.D.
NCT01206296 TERMINATED Adjuvant Intraperitoneal Gemcitabine for Resectable Pancreatic Adenocarcinoma
Medstar Health Research Institute
NCT01839799 COMPLETED A Randomized Phase II/Genomic Trial of Two Chemotherapy Regimens in Patients With Resected Pancreatic Adenocarcinoma
Abramson Cancer Center at Penn Medicine
NCT03040986 COMPLETED Selumetinib Sulfate in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer With KRAS G12R Mutations
National Cancer Institute (NCI)
NCT02921737 TERMINATED TAS-102 (Lonsurf) in Metastatic or Locally Advanced Unresectable Pancreatic Adenocarcinoma Post First Line Chemotherapy (UF-STO-PANC-003)
University of Florida
NCT03415802 COMPLETED Efficacy and Safety of Nab-Paclitaxel Plus S-1 in the First-line Treatment of Advanced Pancreatic Cancer
Aiping Zhou
NCT03585062 TERMINATED Trial of Neoadjuvant Chemotherapy With S1 Plus Paclitaxel-albumin on Pancreatic Cancer
Zhejiang Provincial People's Hospital
NCT01652976 COMPLETED Phase II Study of 5-FU, Oxaliplatin Plus Dasatinib in Metastatic Pancreatic Adenocarcinoma
University of Florida
NCT01964287 COMPLETED First Line Treatment of Patients With Metastatic Pancreatic Adenocarcinoma.
Institut du Cancer de Montpellier - Val d'Aurelle
NCT03979066 TERMINATED Study Evaluating NEOadjuvant Immunotherapy in Resectable PANCreatic Ductal Adenocarcinoma
Gulam Manji
NCT01562899 TERMINATED A Study of MEK162 and AMG 479 in Patients With Selected Solid Tumors
Pfizer
NCT03042780 TERMINATED FOLFIRINOX in Metastatic High Grade Gastroenteropancreatic Neuroendocrine Carcinomas
H. Lee Moffitt Cancer Center and Research Institute
NCT04262388 WITHDRAWN A Multi-Cancer, Multi-State, Platform Study of Durvalumab (MEDI4736) and Oleclumab (MEDI9447) in Pancreatic Adenocarcinoma, Non-Small Cell Lung Cancer and Squamous Cell Carcinoma of the Head and Neck to Correlate Clinical, Molecular and Immunologic Parameters With DNA Methylation
University Health Network, Toronto
NCT01397019 COMPLETED Chemotherapy for Patients With Locally Advanced Pancreatic Cancer (LAPC) With Additional Chemo-radiotherapy (CRT) for Patients With Borderline Resectable Tumours
Per Pfeiffer
NCT03180437 COMPLETED Safety and Efficiency of IRE Plus γδ T Cell Against Locally Advanced Pancreatic Cancer
Fuda Cancer Hospital, Guangzhou
NCT02459652 COMPLETED Neoadjuvant S-1 and Concurrent Radiotherapy for Borderline Resectable Pancreatic Cancer
Japan Adjuvant Study Group of Pancreatic Cancer
NCT03509298 WITHDRAWN Study of Activated Cytokine-induced Killer Armed With Bispecific Antibody for Advanced Pancreatic Cancer
Fuda Cancer Hospital, Guangzhou
NCT02289898 COMPLETED Study of Gemcitabine, Abraxane® Plus Placebo Versus Gemcitabine, Abraxane® Plus 1 or 2 Truncated Courses of Demcizumab in Subjects With 1st-Line Metastatic Pancreatic Ductal Adenocarcinoma
OncoMed Pharmaceuticals, Inc.
NCT03038477 WITHDRAWN A Study of Durvalumab in Patients With BR PDA Following Neoadjuvant Therapy and Successful Surgical Resection
University of Colorado, Denver
NCT00769483 COMPLETED MK-0646 and Gemcitabine +/- Erlotinib for Patients With Advanced Pancreatic Cancer
M.D. Anderson Cancer Center
NCT03213626 TERMINATED Cabozantinib and Erlotinib for Patients With EGFR and c-Met Co-expressing Metastatic Pancreatic Adenocarcinoma
Patrick Joseph Loehrer Sr.
NCT01560949 COMPLETED Preoperative Folfirinox, Radiation Therapy for Resectable Adenocarcinoma of the Pancreas
M.D. Anderson Cancer Center
NCT03469258 TERMINATED Study of Pancreatic Enzyme Replacement on Completion of Adjuvant Chemotherapy for Resected Pancreatic Adenocarcinoma
Dana-Farber Cancer Institute
NCT01222689 COMPLETED Selumetinib and Erlotinib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer
National Cancer Institute (NCI)
NCT00882765 WITHDRAWN Genistein in Treating Patients With Pancreatic Cancer That Can Be Removed by Surgery
Jonsson Comprehensive Cancer Center
NCT01839487 COMPLETED PEGPH20 Plus Nab-Paclitaxel Plus Gemcitabine Compared With Nab-Paclitaxel Plus Gemcitabine in Participants With Stage IV Untreated Pancreatic Cancer
Halozyme Therapeutics
NCT03168139 COMPLETED Olaptesed (NOX-A12) Alone and in Combination With Pembrolizumab in Colorectal and Pancreatic Cancer
TME Pharma AG
NCT02405585 TERMINATED Immunotherapy and SBRT Study in Borderline Resectable Pancreatic Cancer
NewLink Genetics Corporation
NCT00614601 TERMINATED Low Dose Vaccine Study for Surgically Resected Pancreatic Cancer
NewLink Genetics Corporation
NCT01896869 COMPLETED FOLFIRINOX Followed by Ipilimumab With Pancreatic Tumor Vaccine in Treatment of Metastatic Pancreatic Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT02261714 COMPLETED Antigen-specific Cancer Immunotherapy (TG01) and Gemcitabine as Adjuvant Therapy in Resected Pancreatic Cancer
Targovax ASA
NCT03344172 TERMINATED Pre-Operative Trial (PGHA vs. PGH) for Resectable Pancreatic Cancer
Nathan Bahary, MD
NCT02628860 COMPLETED Efficacy of Ferric Carboxymaltose (Ferinject®) in Anemic Patients Anticipating Pancreatoduodenectomy
National Cancer Center, Korea
NCT02713984 WITHDRAWN A Clinical Research of CAR T Cells Targeting HER2 Positive Cancer
Zhi Yang
NCT04058964 WITHDRAWN Pembrolizumab and PEGPH20 in Treating Patients With Metastatic Pancreatic Cancer
M.D. Anderson Cancer Center
NCT01693523 COMPLETED Minocycline Study in Pancreatic Cancer Patients
M.D. Anderson Cancer Center
NCT00727441 COMPLETED Vaccine Therapy With or Without Cyclophosphamide in Treating Patients Undergoing Chemotherapy and Radiation Therapy for Stage I or Stage II Pancreatic Cancer That Can Be Removed by Surgery
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT01392352 TERMINATED HYPAZ: Hypertension Induced by Pazopanib
Cambridge University Hospitals NHS Foundation Trust
NCT04134468 WITHDRAWN MRI Effects of Pegvorhyaluronidase Alfa (PEGPH20) in Pancreatic Ductal Adenocarcinoma
Abramson Cancer Center at Penn Medicine
NCT02743975 TERMINATED Near-infrared Image Guided Surgery in Pancreatic Adenocarcinoma
University Medical Center Groningen
NCT01431794 TERMINATED Gemcitabine + Nab-paclitaxel With LDE-225 (Hedgehog Inhibitor) as Neoadjuvant Therapy for Pancreatic Adenocarcinoma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT02358161 COMPLETED Phase I/II Study of LDE225 With Gemcitabine and Nab-paclitaxel in Patients With Pancreatic Cancer
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
NCT02541370 COMPLETED Treatment of Relapsed and/or Chemotherapy Refractory Advanced Malignancies by CART133
Chinese PLA General Hospital
NCT03300843 TERMINATED Ability of a Dendritic Cell Vaccine to Immunize Melanoma or Epithelial Cancer Patients Against Defined Mutated Neoantigens Expressed by the Autologous Cancer
National Cancer Institute (NCI)
NCT01240304 TERMINATED A Phase II Study to Assess the Efficacy and Safety of Preoperative Chemo With Radiation Therapy for Patients With Borderline Unresectable Adenocarcinoma of the Pancreas
University of Arkansas
NCT00728000 WITHDRAWN Phase II Study Of Neoadjuvant Chemotherapy In Borderline Resectable Pancreatic Adenocarcinoma
University of Cincinnati
NCT02749136 COMPLETED Neoadjuvant Modified FOLFIRINOX in Borderline Resectable Pancreatic Cancer
Asan Medical Center
NCT02981342 COMPLETED A Study of Abemaciclib (LY2835219) Alone or in Combination With Other Agents in Participants With Previously Treated Pancreatic Ductal Adenocarcinoma
Eli Lilly and Company
NCT03891472 COMPLETED Clinical Phase II Clinical Study Evaluating the Toxicity and Efficacy of mFOLFIRINOX Associated With SBRT (Stereotactic Radiotherapy) in Patients With Unresectable Locally Advanced Pancreatic Cancer
Medical University of Silesia
NCT01661088 COMPLETED A Study of Neoadjuvant FOLFIRINOX and FDR-Gemcitabine With Concurrent IMRT in Patients
University of Michigan Rogel Cancer Center
NCT02106884 COMPLETED Quality of Life in Locally Advanced or Metastatic Pancreatic Cancer Treated With Gemcitabine and Nab-paclitaxel
Universitaire Ziekenhuizen KU Leuven
NCT00733746 COMPLETED Gemcitabine and Erlotinib Before and After Surgery in Treating Patients With Pancreatic Cancer That Can Be Removed by Surgery
Alliance for Clinical Trials in Oncology
NCT04130399 WITHDRAWN Study of Neoadjuvent Chemotherapy Followed by SBRT in Patients With Resectable and Borderline Resectable Pancreatic Cancer
Indiana University
NCT01583686 TERMINATED CAR T Cell Receptor Immunotherapy Targeting Mesothelin for Patients With Metastatic Cancer
National Cancer Institute (NCI)
NCT02043730 COMPLETED Abraxane and Gemcitabine Versus Gemcitabine Alone in Locally Advanced Unresectable Pancreatic Cancer.
Gruppo Italiano per lo studio dei Carcinomi dell'Apparato Digerente
NCT01806675 COMPLETED 18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy
Sanjiv Sam Gambhir
NCT02362048 COMPLETED ACP-196 Alone and in Combination With Pembrolizumab in Subjects With Advanced or Metastatic Pancreatic Cancer
Acerta Pharma BV
NCT01524575 WITHDRAWN Gemcitabine and Oxaliplatin in the Management of Metastatic Pancreatic Cancers With Low Expression of ERCC1
University of Hawaii
NCT01505530 COMPLETED A Phase 2 Study of LY2495655 in Participants With Pancreatic Cancer
Eli Lilly and Company
NCT02449967 WITHDRAWN HepaSphere Interventional Therapy Using Digital Subtraction Angiography(DSA) for Pancreatic Cancer
Fuda Cancer Hospital, Guangzhou
NCT01028495 COMPLETED A Safety and Efficacy Study of RX-0201 Plus Gemcitabine in Metastatic Pancreatic Cancer
Rexahn Pharmaceuticals, Inc.
NCT03008304 COMPLETED High-activity Natural Killer Immunotherapy for Small Metastases of Pancreatic Cancer
Fuda Cancer Hospital, Guangzhou
NCT02718859 COMPLETED Combination of Irreversible Electroporation and NK Immunotherapy for Advanced Pancreatic Cancer
Fuda Cancer Hospital, Guangzhou
NCT02570711 TERMINATED Phase 2, Nab Paclitaxel/Gemcitabine Alone and in Combination With ACP-196 in Subjects With Metastatic Pancreatic Cancer
Acerta Pharma BV
NCT02352831 TERMINATED Tosedostat With Capecitabine in Patients With Metastatic Pancreatic Adenocarcinoma
Washington University School of Medicine
NCT02583477 COMPLETED Phase Ib/II Study of MEDI4736 Evaluated in Different Combinations in Metastatic Pancreatic Ductal Carcinoma
AstraZeneca
NCT01858883 COMPLETED Safety Study of Itacitinib (INCB039110) in Combination With Gemcitabine and Nab-Paclitaxel in Subjects With Advanced Solid Tumors
Incyte Corporation
NCT02124369 TERMINATED Pancreatic Resectability in Cancers With Known Limited Extension (PRICKLE)
CCTU- Cancer Theme
NCT03529175 COMPLETED Scheduling Nab-paclitaxel With Gemcitabine
CCTU- Cancer Theme
NCT01313416 TERMINATED Gemcitabine and CT-011 for Resected Pancreatic Cancer
Augusta University
NCT02736578 TERMINATED Cetuximab-IRDye 800CW and Intraoperative Imaging in Finding Pancreatic Cancer in Patients Undergoing Surgery
Eben Rosenthal
NCT01132755 COMPLETED Rapid Gastric and Pancreas Cancer Staging Utilizing Peritoneal Lavage
Memorial Sloan Kettering Cancer Center
NCT03697239 WITHDRAWN High Dose Ascorbic Acid (AA) + Nanoparticle Paclitaxel Protein Bound + Cisplatin + Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancer
Hitendra Patel
NCT03797443 WITHDRAWN High Dose Ascorbic Acid (AA) + Nanoparticle Paclitaxel Protein Bound + Cisplatin + Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancer
Piedmont Cancer Institute
NCT03432676 WITHDRAWN Epacadostat and Pembrolizumab in Treating Participants With Advanced Pancreatic Cancer
M.D. Anderson Cancer Center
NCT03908333 WITHDRAWN High Dose Ascorbic Acid and Nanoparticle Paclitaxel Protein Bound and Cisplatin and Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancer
Medical College of Wisconsin
NCT01893801 COMPLETED Nab-Pac+Cis+Gem in Pts w Previously Untreated Metastatic PDA
Pancreatic Cancer Research Team
NCT03392571 WITHDRAWN Phase II Study of NGC-Triple Regimen in Potentially Resectable Pancreatic Cancer Patients
Pancreatic Cancer Research Team
NCT01128296 COMPLETED Study of Pre-surgery Gemcitabine + Hydroxychloroquine (GcHc) in Stage IIb or III Adenocarcinoma of the Pancreas
Amer Zureikat
NCT01088815 COMPLETED Hedgehog Inhibitors for Metastatic Adenocarcinoma of the Pancreas
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT00923299 COMPLETED Cetuximab and Trastuzumab in Treating Patients With Metastatic Pancreatic Cancer That Progressed After Previous Treatment With Gemcitabine
Institut du Cancer de Montpellier - Val d'Aurelle
NCT02910882 TERMINATED PEGPH20 Plus Gemcitabine With Radiotherapy in Patients With Localized, Unresectable Pancreatic Cancer
Scripps Health
NCT02950025 TERMINATED Daily Online Adaptation Versus Localization for MRI-Guided SBRT for Unresectable Primary or Oligometastatic Abdominal Malignancies
Washington University School of Medicine
NCT00735917 COMPLETED Saracatinib in Treating Patients With Previously Treated Metastatic Pancreatic Cancer
National Cancer Institute (NCI)
NCT01978184 COMPLETED Randomized Phase II Trial of Pre-Operative Gemcitabine and Nab Paclitacel With or With Out Hydroxychloroquine
Nathan Bahary, MD
NCT01760252 TERMINATED Neoadjuvant CAPOXIRI Chemotherapy in the Treatment of Pancreatic Adenocarcinoma Protocol
Beth Israel Medical Center
NCT01233375 COMPLETED Study to Evaluate Efficacy of CO-1.01 as Second Line Therapy for Gemcitabine-Refractory Stage IV Pancreatic Adenocarcinoma
Clovis Oncology, Inc.
NCT02440958 COMPLETED Modified FOLFIRINOX for Gemcitabine Refractory Pancreatic Cancer: A Phase II Multicenter Trial
Yonsei University
NCT02023021 COMPLETED Nab-paclitaxel Combined With Gemcitabine as Adjuvant Therapy for Pancreatic Cancer After Curative Resection
Xian-Jun Yu
NCT02005419 COMPLETED Metformin Combined With Gemcitabine as Adjuvant Therapy for Pancreatic Cancer After Curative Resection
Xian-Jun Yu
NCT02732938 TERMINATED Ph1b/2 Study of PF-04136309 in Combination With Gem/Nab-P in First-line Metastatic Pancreatic Patients
Pfizer
NCT01632306 TERMINATED A Study of LY2090314 and Chemotherapy in Participants With Metastatic Pancreatic Cancer
Eli Lilly and Company
NCT02403271 COMPLETED A Multi-Center Study of Ibrutinib in Combination With MEDI4736 in Subjects With Relapsed or Refractory Solid Tumors
Pharmacyclics LLC.
NCT01453153 COMPLETED Study of Gemcitabine + PEGPH20 vs Gemcitabine Alone in Stage IV Previously Untreated Pancreatic Cancer
Halozyme Therapeutics
NCT03627390 COMPLETED BP-C1 in Short-term Treatment of Metastatic Pancreatic Cancer
Meabco A/S
NCT02669914 TERMINATED MEDI4736 (Durvalumab) in Patients With Brain Metastasis From Epithelial-derived Tumors
Washington University School of Medicine
NCT01032057 COMPLETED Gemcitabine, Capecitabine, and Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer That Cannot Be Removed by Surgery
Lisette Nixon
NCT02399137 COMPLETED A Phase 2 Study of MM-141 Plus Nab-paclitaxel and Gemcitabine in Front-line Metastatic Pancreatic Cancer
Merrimack Pharmaceuticals
NCT02967770 WITHDRAWN Molecularly Tailored Therapy to Standard of Care as Second-Line Therapy in Metastatic Pancreatic Cancer
Georgetown University
NCT01621243 TERMINATED M402 in Combination With Nab-Paclitaxel and Gemcitabine in Pancreatic Cancer
Momenta Pharmaceuticals, Inc.
NCT02558894 COMPLETED Phase II Study of MEDI4736 Monotherapy or in Combinations With Tremelimumab in Metastatic Pancreatic Ductal Carcinoma
AstraZeneca
NCT02195180 COMPLETED Efficacy and Safety of L-asparaginase Encapsulated in RBC Combined With Gemcitabine or FOLFOX in 2nd Line for Progressive Metastatic Pancreatic Carcinoma
ERYtech Pharma
NCT02241551 TERMINATED Phase II Neoadjuvant Chemotheraphy (Gemcitabine and Nab-Paclitaxel vs. mFOLFIRINOX) and Sterotatic Body Radiation Therapy for Borderline Resectable Pancreatic Cancer
Nathan Bahary, MD
NCT01921751 TERMINATED High or Standard Intensity Radiation Therapy After Gemcitabine Hydrochloride and Nab-paclitaxel in Treating Patients With Pancreatic Cancer That Cannot Be Removed by Surgery
Radiation Therapy Oncology Group
NCT02345460 TERMINATED Preoperative Folfirinox for Resectable Pancreatic Adenocarcinoma - A Phase II Study
Case Comprehensive Cancer Center
NCT02767752 TERMINATED Gemcitabine and Capecitabine With or Without T-ChOS as Adjuvant Therapy for Patients With Resected Pancreatic Cancer
Herlev Hospital
NCT02331251 TERMINATED Study of Pembrolizumab Plus Chemotherapy in Patients With Advanced Cancer (PembroPlus)
Western Regional Medical Center
NCT02423954 TERMINATED Study of Nivolumab Plus Chemotherapy in Patients With Advanced Cancer (NivoPlus)
Western Regional Medical Center
NCT02004262 COMPLETED Safety and Efficacy of Combination Listeria/GVAX Pancreas Vaccine in the Pancreatic Cancer Setting
Aduro Biotech, Inc.
NCT01389440 COMPLETED Efficacy and Safety of a Neoadjuvant Treatment in Pancreatic Cancer
Grupo Espanol Multidisciplinario del Cancer Digestivo
NCT01373164 COMPLETED A Study in Metastatic Cancer and Advanced or Metastatic Unresectable Pancreatic Cancer
Eli Lilly and Company
NCT00889187 TERMINATED Neoadjuvant Accelerated Short Course Radiation Therapy With Photons and Capecitabine for Resectable Pancreatic Cancer
Dana-Farber Cancer Institute
NCT01417000 COMPLETED Safety and Efficacy of Combination Listeria/GVAX Immunotherapy in Pancreatic Cancer
Aduro Biotech, Inc.
NCT01888978 COMPLETED Molecularly Tailored Therapy for Pancreas Cancer
Georgetown University
NCT02638909 TERMINATED Study of Oral Ceritinib in Patients With ALK and ROS1 Activated Gastrointestinal Malignancies
Criterium, Inc.
NCT01280058 COMPLETED Carboplatin and Paclitaxel With or Without Viral Therapy in Treating Patients With Recurrent or Metastatic Pancreatic Cancer
National Cancer Institute (NCI)
NCT01423604 COMPLETED Study of Ruxolitinib in Pancreatic Cancer Patients
Incyte Corporation
NCT01851174 TERMINATED Study to Evaluate Bi-weekly Dosing of Gemcitabine Plus Nab-Paclitaxel to Treat Metastatic Pancreatic Cancer
Western Regional Medical Center
NCT01781520 COMPLETED Study of S-1 Plus DC-CIK for Patients With Unresectable Locally Advanced Pancreatic Cancer
Capital Medical University
NCT00810719 COMPLETED Gemcitabine and Erlotinib in Treating Patients With Metastatic or Recurrent Pancreatic Cancer
University of California, Davis
NCT01234935 COMPLETED Dasatinib and Gemcitabine Hydrochloride or Gemcitabine Hydrochloride Alone in Treating Patients With Pancreatic Cancer Previously Treated With Surgery
Translational Oncology Research International
NCT01056601 TERMINATED Panobinostat & Bortezomib in Pancreatic Cancer Progressing on Gemcitabine Therapy
Masonic Cancer Center, University of Minnesota
NCT01146054 COMPLETED Phase II Gemcitabine + Fractionated Stereotactic Radiotherapy for Unresectable Pancreatic Adenocarcinoma
Stanford University
NCT00903396 TERMINATED Palonosetron Hydrochloride in Preventing Nausea and Vomiting Caused by Radiation Therapy in Patients With Primary Abdominal Cancer
Alliance for Clinical Trials in Oncology
NCT01430052 COMPLETED Chemoradiotherapy With Gemcitabine/S-1 vs Gemcitabine/S-1 for Locally Advanced Pancreatic Cancer
Osaka Medical Center for Cancer and Cardiovascular Diseases
NCT01688336 TERMINATED FOLFIRINOX for Unresectable Locally Advanced and Borderline Resectable Pancreatic Cancer
UNC Lineberger Comprehensive Cancer Center
NCT01553019 COMPLETED Postoperative Proton Radiotherapy With Chemo for Pancreatic Cancer
University of Florida
NCT01150630 COMPLETED Gemcitabine, Cisplatin, Epirubicin, and Capecitabine in Treating Patients With Stage I-II Resectable Pancreatic Cancer
IRCCS San Raffaele
NCT01730222 COMPLETED A Phase I-II Study of PAXG in Stage III-IV Pancreatic Adenocarcinoma
IRCCS San Raffaele
NCT01523457 COMPLETED Study of Modified FOLFIRINOX in Advanced Pancreatic Cancer
Yale University
NCT01531712 TERMINATED Study of Neoadjuvant Treatment in Patients With Pancreatic Cancer That is Potentially Resectable
Institut Català d'Oncologia
NCT01195415 COMPLETED Vismodegib and Gemcitabine Hydrochloride in Treating Patients With Advanced Pancreatic Cancer
National Cancer Institute (NCI)
NCT01040000 COMPLETED QUILT-3.019: Phase 2 Study of NPC-1C Chimeric Monoclonal Antibody to Treat Pancreatic and Colorectal Cancer
Precision Biologics, Inc
NCT01303029 COMPLETED Safety and Efficacy Study of Gemcitabine-erlotinib Versus Gemcitabine-erlotinib-capecitabine in Patients With Metastatic Pancreatic Cancer
Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)
NCT02035072 COMPLETED Phase II Study of Hypofractionated Radio-chemotherapy With Gemcitabine Plus Oxaliplatin for Unresectable Nonmetastatic Locally Advanced Pancreatic Cancer.
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
NCT00609336 COMPLETED Perioperative Therapy for Resectable Pancreatic Cancer
University of Washington
NCT01016483 COMPLETED Trial of Gemcitabine With or Without MSC1936369B in Pancreatic Cancer
EMD Serono
NCT02117258 COMPLETED Z-360 Plus GEM in Subjects With Metastatic Pancreatic Adenocarcinoma
Zeria Pharmaceutical
NCT01273805 COMPLETED Hydroxychloroquine in Previously Treated Patients With Metastatic Pancreatic Cancer
Dana-Farber Cancer Institute
NCT01515046 TERMINATED Clinical Trial of High-dose Vitamin C for Advanced Pancreatic Cancer
Joseph J. Cullen
NCT00841035 TERMINATED 7 Day's of Erlotinib Neo-adjuvant, Followed by Adjuvant Erlotinib-gemcitabine in Pancreatic Cancer Patients
University of Alabama at Birmingham
NCT02243007 TERMINATED Phase II Study of Preoperative FOLFIRINOX Versus Gemcitabine/Nab-Paclitaxel in Patients With Resectable Pancreatic Cancer
Massachusetts General Hospital
NCT01844817 COMPLETED Phase II Trial Of Gemcitabine Plus Nab-Paclitaxel +/- OGX-427 In Patients With Metastatic Pancreatic Cancer
SCRI Development Innovations, LLC
NCT01608711 COMPLETED A Study of AGS-1C4D4 in Pancreatic Cancer Subjects Previously Treated in Protocol 2008002
Agensys, Inc.
NCT02202785 TERMINATED A Study of MLN0264 in Patients With Pancreatic Cancer
Millennium Pharmaceuticals, Inc.
NCT00691054 COMPLETED Abraxane Therapy in Patients With Pancreatic Cancer Who Failed First-Line Gemcitabine Therapy
University of Miami
NCT00948688 TERMINATED Vorinostat With XRT and 5-FU for Locally Advanced Adenocarcinoma of the Pancreas
Massachusetts General Hospital
NCT01558869 COMPLETED Xeloxiri as First-line Treatment in Patients With Advanced Unresectable Pancreatic Adenocarcinoma
The University of Hong Kong
NCT01272791 COMPLETED Trial of Gemcitabine With or Without Bavituximab in Patients With Previously Untreated Stage IV Pancreatic Cancer
Peregrine Pharmaceuticals
NCT00601627 COMPLETED Panitumumab, Chemotherapy, and External-Beam Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer That Cannot be Removed by Surgery
Alliance for Clinical Trials in Oncology
NCT00550836 COMPLETED Erlotinib and Gemcitabine With or Without Panitumumab in Treating Patients With Metastatic Pancreatic Cancer
Alliance for Clinical Trials in Oncology
NCT00907166 TERMINATED A Phase I/II Open-Label Dose-Escalation Clinical Trial of CPI-613 in Combination With Gemcitabine in Cancer Patients
Cornerstone Pharmaceuticals
NCT01175733 COMPLETED Chemoradiation With Gemcitabine in Combination With Panitumumab for Patients With Locally Advanced Pancreatic Cancer
Amsterdam UMC, location VUmc
NCT01130142 COMPLETED A Study Evaluating IPI-926 in Combination With Gemcitabine in Patients With Metastatic Pancreatic Cancer
Infinity Pharmaceuticals, Inc.
NCT01895790 WITHDRAWN Endoscopic Pancreatic Duct Stenting for Relief of Obstructive Pain in Patients With Pancreatic Cancer
Johns Hopkins University
NCT01108458 TERMINATED A Phase 2 Study of Pertuzumab and Erlotinib for Refractory Pancreatic Adenocarcinoma
George Albert Fisher
NCT01581307 COMPLETED Phase II Trial Evaluating OS With Therasphere® + 2nd-Line FOLFOX in Pancreatic Liver Mets
H. Lee Moffitt Cancer Center and Research Institute
NCT00944463 COMPLETED Trial of Simvastatin and Gemcitabine in Pancreatic Cancer Patients
Samsung Medical Center
NCT02242409 TERMINATED Study of Gemcitabine and Abraxane for Pancreas Cancer
Georgetown University
NCT02109341 COMPLETED Phase I/II Study to Evaluate Nab-paclitaxel in Substitution of CPT11 or Oxaliplatin in FOLFIRINOX Schedule as First Line Treatment in Metastatic Pancreatic Cancer
Gruppo Oncologico Italiano di Ricerca Clinica
NCT03016637 COMPLETED Pancreatic Core Biopsy Needle Study in Patients Suspected of Pancreatic Malignancy
Odense University Hospital
NCT02984501 COMPLETED Study of Induction Chemotherapy Followed by Radiochemotherapy in Locally Advanced Pancreatic Cancer
Campus Bio-Medico University
NCT01369420 COMPLETED NanoKnife Low Energy Direct Current (LEDC) System in Subjects With Locally Advanced Unresectable Pancreatic Cancer
Angiodynamics, Inc.
NCT01661114 COMPLETED A Trial of Gemcitabine, Infusional 5-Fluorouracil and Cisplatin for Advanced Pancreatic and Biliary Cancers
University of Michigan Rogel Cancer Center
NCT01050426 TERMINATED A Clinical Study of UFT/Leucovorin, Radiotherapy With or Without Cetuximab Following Induction Gemcitabine Plus Capecitabine in Patients With Locally Advanced Pancreatic Cancer (PERU)
Royal Marsden NHS Foundation Trust
NCT00726037 TERMINATED A Pilot Study, Evaluating the Efficacy of Regulatory T-cell Suppression by Ontak in Metastatic Pancreatic Cancer
Loyola University
NCT01188109 TERMINATED Gemcitabine/Cisplatin for Resected Pancreas Cancer: Establishing the Role of ERCC1 in Treatment Decision
Emory University
NCT01488552 COMPLETED Gemcitabine+Nab-paclitaxel and FOLFIRINOX and Molecular Profiling for Patients With Advanced Pancreatic Cancer
Pancreatic Cancer Research Team
NCT01304160 COMPLETED Role of Cyberknife Stereotactic Radiation Therapy (SBRT) Followed by Gemcitabine for Patients With Locally Advanced Pancreatic Cancer
Centre hospitalier de l'Université de Montréal (CHUM)
NCT02382263 COMPLETED Nab-paclitaxel in Combination With Gemcitabine in Fragile Patients With Advanced Pancreatic Cancer
PH Research, S.L.
NCT01473303 WITHDRAWN Combination Chemotherapy With or Without Ganitumab in Treating Patients With Previously Untreated Metastatic Pancreatic Cancer
Alliance for Clinical Trials in Oncology
NCT00674973 COMPLETED A Biomarker Identification Trial of Tarceva (Erlotinib) in Patients With Advanced Pancreatic Cancer
Hoffmann-La Roche
NCT00871169 COMPLETED Combination of Irinotecan, Oxaliplatin and Cetuximab for Locally Advanced or Metastatic Pancreatic Cancer
New Mexico Cancer Research Alliance
NCT01416662 COMPLETED Gemcitabine Hydrochloride in Treating Patients With Pancreatic Cancer That Has Been Removed by Surgery
Federation Francophone de Cancerologie Digestive
NCT00766636 TERMINATED Preoperative Chemotherapy (Gemcitabine and Erlotinib) With or Without Radiation Therapy
M.D. Anderson Cancer Center
NCT01415713 COMPLETED The Study of Metastatic Pancreatic Adenocarcinoma
National Health Research Institutes, Taiwan
NCT01395017 COMPLETED Dasatinib Added to Gemcitabine for Subjects With Locally-advanced Pancreatic Cancer
Otsuka Pharmaceutical Development & Commercialization, Inc.
NCT01658943 COMPLETED Selumetinib and Akt Inhibitor MK2206 or mFOLFOX Therapy Comprising Oxaliplatin and Fluorouracil in Treating Patients With Metastatic Pancreatic Cancer Previously Treated With Chemotherapy
National Cancer Institute (NCI)
NCT01693276 TERMINATED Gemcitabine/Abraxane Chemotherapy and Dose Escalated Radiotherapy for Locally Advanced, Unresectable Pancreatic Cancer
Olugbenga Olowokure
NCT01042028 TERMINATED A Randomised Trial With Irinotecan, Cetuximab and Everolimus (ICE)Compared to Capecitabine and Oxaliplatin (CapOx) for Patients With Gemcitabin Resistant Pancreatic Cancer
Per Pfeiffer
NCT00633789 COMPLETED Phase II Study of Brivanib (BMS-582664) to Treat Multiple Tumor Types
Bristol-Myers Squibb
NCT00902291 COMPLETED A Study of AGS-1C4D4 Given in Combination With Gemcitabine in Subjects With Metastatic Pancreatic Cancer
Astellas Pharma Inc
NCT01754623 TERMINATED GTX-RT in Borderline Resectable Pancreatic Cancer
H. Lee Moffitt Cancer Center and Research Institute
NCT00733850 COMPLETED Safety and Exploratory Efficacy of Kanglaite Injection in Pancreatic Cancer
KangLaiTe USA
NCT01298011 COMPLETED Study of Gemcitabine and Abraxane to Treat Potentially Operable Pancreatic Cancer
Pancreatic Cancer Research Team
NCT01080248 TERMINATED Gemcitabine and Pazopanib in Metastatic Pancreatic Cancer
Washington University School of Medicine
NCT00743379 COMPLETED Dose-Escalation Study of TH-302 in Combination With A) Gemcitabine or B) Docetaxel or C) Pemetrexed to Treat Advanced Solid Tumors
Threshold Pharmaceuticals
NCT01167738 TERMINATED Combination Chemotherapy With or Without Metformin Hydrochloride in Treating Patients With Metastatic Pancreatic Cancer
IRCCS San Raffaele
NCT01587534 COMPLETED Pancreatic Enzyme Supplementation in Patients With Unresectable Pancreatic Cancer (PESUP)
National Cancer Center, Korea
NCT00998322 COMPLETED A Study of REOLYSIN® in Combination With Gemcitabine in Patients With Advanced Pancreatic Adenocarcinoma
Oncolytics Biotech
NCT01130701 WITHDRAWN A Pilot Study to Evaluate the Efficacy and Safety of Neoadjuvant Chemoradiotherapy With Capecitabine, . . .
University of Massachusetts, Worcester
NCT01472198 COMPLETED A Study to Evaluate the Efficacy and Safety of Simtuzumab Combined With Gemcitabine for Metastatic Pancreatic Adenocarcinoma
Gilead Sciences
NCT00652366 COMPLETED A Dose-Escalation to Rash Study of Tarceva (Erlotinib) Plus Gemcitabine in Patients With Metastatic Pancreatic Cancer
Hoffmann-La Roche
NCT01628458 COMPLETED Safety Study of Radiofrequency Ablation of Locally Advanced Pancreatic Cancer
UMC Utrecht
NCT00962312 COMPLETED Lapatinib Ditosylate and Capecitabine in Treating Patients With Metastatic Pancreatic Cancer
Cancer Trials Ireland
NCT01232829 COMPLETED Gamma Secretase Inhibitor RO4929097 in Previously Treated Metastatic Pancreas Cancer
National Cancer Institute (NCI)
NCT01593995 COMPLETED EGF Ointment for Erlotinib Skin Lesion
Dong-A University Hospital
NCT01339754 COMPLETED Trabectedin in Treating Patients With Metastatic Pancreatic Cancer After First-Line Chemotherapy
IRCCS San Raffaele
NCT00577889 COMPLETED Gemcitabine Hydrochloride and Tanespimycin in Treating Patients With Stage IV Pancreatic Cancer
National Cancer Institute (NCI)
NCT01227018 TERMINATED PhII Study STA-9090 as Second or Third-Line Therapy for Metastatic Pancreas Cancer
Vanderbilt-Ingram Cancer Center
NCT00837876 COMPLETED Sorafenib and Erlotinib in Treating Patients With Pancreatic Cancer That Cannot Be Removed by Surgery
Vanderbilt-Ingram Cancer Center
NCT01971034 COMPLETED Treatment of Patients With Advanced Pancreatic Cancer After Gemcitabine Failure.
Instituto do Cancer do Estado de São Paulo
NCT01020006 COMPLETED Study of Safety and Tolerability of PCI-27483 in Patients With Pancreatic Cancer Patients Receiving Treatment With Gemcitabine
Pharmacyclics LLC.
NCT01124786 COMPLETED A Study Comparing CO-1.01 With Gemcitabine as First Line Therapy in Patients With Metastatic Pancreatic Adenocarcinoma (LEAP)
Clovis Oncology, Inc.
NCT01505413 COMPLETED Phase 2 Study of Erlotinib, Gemcitabine and Oxaliplatin Combination Chemotherapy to Advanced Pancreatic Cancer
Soonchunhyang University Hospital
NCT00636883 TERMINATED Oxaliplatin, Gemcitabine, and Erlotinib Study in Patients With Advanced Chemo-naïve Pancreatic Cancer
National Guard Health Affairs
NCT00910741 COMPLETED NC-6004(Nanoplatin) and Gemcitabine to Treat Pancreatic Cancer in Asia
NanoCarrier Co., Ltd.
NCT01096732 TERMINATED Hedgehog Inhibition for Pancreatic Ductal Adenocarcinoma (PDAC) in the Preoperative Setting (HIPPoS)
Lisa Bax
NCT01830322 WITHDRAWN Safety and Effectiveness Study of CPI-613 and/or Gemcitabine to Treat Metastatic Pancreatic Cancer
Cornerstone Pharmaceuticals
NCT00837031 COMPLETED Lenalidomide With Gemcitabine in Treatment of Untreated Advanced Carcinoma of the Pancreas
SCRI Development Innovations, LLC
NCT00959946 TERMINATED Study Of Bosutinib With Capecitabine In Solid Tumors And Locally Advanced Or Metastatic Breast Cancer
Pfizer
NCT00922896 COMPLETED Trial of Erlotinib, Gemcitabine and Cisplatin in Metastatic Pancreatic Cancer
Gyeongsang National University Hospital
NCT00709826 COMPLETED APRiCOT-P: Study of Apricoxib With Gemcitabine and Erlotinib to Treat Advanced Pancreatic Cancer
Tragara Pharmaceuticals, Inc.
NCT00862524 COMPLETED A Study of ARRY-334543 and Gemcitabine in Patients With Advanced Cancer and Pancreatic Cancer
Array BioPharma
NCT01186731 COMPLETED Efficacy and Safety Study of LE-DT to Treat Locally Advanced or Metastatic Pancreatic Cancer
INSYS Therapeutics Inc
NCT01196247 COMPLETED A Study of Therapy Selected by Molecular/Metabolic Profiling in Patients With Previously Treated Metastatic Pancreatic Cancer
Translational Drug Development
NCT01320241 COMPLETED Radiation Stent Versus Self-expanding Metallic Stents (SEMS) for Palliative Treatment of Malignant Biliary Stricture
Southeast University, China
NCT01543412 COMPLETED Second Line Chemotherapy for Advanced Pancreatic Cancer
Gruppo Italiano per lo studio dei Carcinomi dell'Apparato Digerente
NCT00831493 TERMINATED Vorinostat Plus Radiation Therapy in Pancreatic Cancer
M.D. Anderson Cancer Center
NCT00967603 COMPLETED Maintenance Therapy With Sunitinib or Observation in Metastatic Pancreatic Cancer
IRCCS San Raffaele
NCT00898287 COMPLETED Safety and Efficacy Study of P276-00 in Combination With Gemcitabine in Patients With Advanced Pancreatic Cancer
Piramal Enterprises Limited
NCT00673504 COMPLETED First-Line Gemcitabine Chemotherapy With Our Without Sunitinib In Advanced or Metastatic Pancreatic Cancer
Central European Society for Anticancer Drug Research
NCT00683085 TERMINATED Human Leukocyte Antigen-A*02:01-restricted Tumor Vessel Specific Peptide Vaccination for Advanced Pancreatic Cancer
Tokyo University
NCT00810953 COMPLETED A Safety Study Using Pentamidine in Patients With Pancreatic Cancer Undergoing Standard Therapy
Oncozyme Pharma Inc.
NCT00761241 COMPLETED Borderline Resectable Pancreatic Cancer: Gemcitabine/Docetaxel and Oxaliplatin Based Chemo/RT
Benaroya Research Institute
NCT00637364 SUSPENDED High Intensity Focused Ultrasound Tumor Treatment for Pancreatic Cancer Pain
CMED HIFU Development Corporation