Sarcoma Clinical Trial Landscape
Data updated: May 20, 2026
1,026 clinical trials tracked since 2008
Sarcomas are a diverse group of cancers that develop in the bone and soft tissues of the body. These tumors are relatively rare, accounting for a small percentage of all adult and childhood cancers. The clinical trial landscape for sarcoma includes 1,026 registered trials since 2008, with 430 trials currently active, meaning they are recruiting, enrolling, or active but not recruiting. Activity is concentrated in early- to mid-stage development, with 192 active Phase 1 trials out of 479 total and 283 active Phase 2 trials out of 646 total. Phase 3 trials are less numerous, with 31 active trials out of 73 total. A limited number of Phase 4 trials are ongoing, with 6 active trials out of 11 total. Hansoh BioMedical R&D Company and Philogen S.p.A. are the leading industry sponsors in the active trial landscape, each sponsoring 3 active trials. Eli Lilly, Pfizer, and Chia Tai Tianqing Pharmaceutical Group Co., Ltd. each sponsor 2 active trials.
422 active
/
1026 total (since 2008)
187
Phase 1 Active
478 total
279
Phase 2 Active
648 total
29
Phase 3 Active
72 total
6
Phase 4 Active
11 total
Top Industry Sponsors
Sorted by active Active Done Failed
USWM CT, LLC 3 0 0
Hansoh BioMedical R&D Company 3 0 0
Eli Lilly 2 8 3
Pfizer 2 3 5
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 2 0 3
+ 10 more sponsors — see full table below
Featured Phase 3 Trials
NCT05691478 RECRUITING
A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma
National Cancer Institute (NCI) n=1,122
NCT06422806 RECRUITING
Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas
National Cancer Institute (NCI) n=365
NCT05432791 ACTIVE NOT RECRUITING
Testing Olaparib and Temozolomide Versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy Has Stopped Working
National Cancer Institute (NCI) n=74
NCT05235165 RECRUITING
Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma
Children's Oncology Group n=62
NCT02180867 ACTIVE NOT RECRUITING
Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery
National Cancer Institute (NCI) n=140
+ 67 more Phase 3 trials — see full database below
Sarcoma — Trials Started by Year (last 10 years)
2016 58
2017 58
2018 53
2019 57
2020 60
2021 81
2022 60
2023 68
2024 74
2025 69
2026 47
TheraRadar.com
Full Trial Database
Complete sponsor table, every trial across all phases, plus competitive analytics. Sortable, filterable, exportable for Pro users.
Top Sponsors (all-time)
USWM CT, LLC 3
Hansoh BioMedical R&D Company 3
Eli Lilly 13
Pfizer 10
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 5
Amgen 3
Lantheus Medical Imaging 2
Novartis 5
PharmaMar 3
Merck 3
Active Trials by Phase
Phase 1 187
Phase 2 279
Phase 3 29
Phase 4 6
Enrollment Size Distribution
1-50 601
51-200 293
201-500 59
501-1k 14
1k+ 5
All Industry Sponsors
Sorted by active Active Done Failed
USWM CT, LLC 3 0 0
Hansoh BioMedical R&D Company 3 0 0
Eli Lilly 2 8 3
Pfizer 2 3 5
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 2 0 3
Amgen 2 1 0
Lantheus Medical Imaging 2 0 0
Novartis 1 3 1
PharmaMar 1 2 0
Merck 1 1 1
MacroGenics 1 1 1
GSK 1 1 1
HiFiBiO Therapeutics 1 0 1
Intensity Therapeutics, Inc. 1 1 0
Telix Pharmaceuticals (Innovations) Pty Ltd 1 0 1
NCT05691478 RECRUITING
A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma
National Cancer Institute (NCI) n=1,122
NCT06422806 RECRUITING
Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas
National Cancer Institute (NCI) n=365
NCT05432791 ACTIVE NOT RECRUITING
Testing Olaparib and Temozolomide Versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy Has Stopped Working
National Cancer Institute (NCI) n=74
NCT05235165 RECRUITING
Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma
Children's Oncology Group n=62
NCT02180867 ACTIVE NOT RECRUITING
Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery
National Cancer Institute (NCI) n=140
NCT05712694 RECRUITING
Study of ADI-PEG 20 or Placebo Plus Gem and Doc in Previously Treated Subjects With Leiomyosarcoma (ARGSARC)
Polaris Group n=300
NCT06088290 ACTIVE NOT RECRUITING
Study of Lurbinectedin in Combination With Doxorubicin Versus Doxorubicin Alone as First-line Treatment in Participants With Metastatic Leiomyosarcoma (SaLuDo)
PharmaMar n=455
NCT04307277 RECRUITING
Interest of Peri Operative CHemotherapy In Patients With CINSARC High-risk Localized Soft Tissue Sarcoma
Institut Claudius Regaud n=600
NCT02306161 ACTIVE NOT RECRUITING
Combination Chemotherapy With or Without Ganitumab in Treating Patients With Newly Diagnosed Metastatic Ewing Sarcoma
National Cancer Institute (NCI) n=312
NCT06935409 ACTIVE NOT RECRUITING
Study of HS-20093 Versus Gemcitabine in Combination With Docetaxel in Treatment of Osteosarcoma After Previous Second-line Treatment Failure
Hansoh BioMedical R&D Company n=117
NCT04031677 RECRUITING
Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma
European Organisation for Research and Treatment of Cancer - EORTC n=250
NCT03016819 RECRUITING
Phase III Trial of Anlotinib, Catequentinib in Advanced Alveolar Soft Part Sarcoma, Leiomyosarcoma, Synovial Sarcoma (APROMISS)
Advenchen Laboratories, LLC n=325
NCT06820957 ACTIVE NOT RECRUITING
Testing a New Combination of Anti-cancer Drugs in Patients Newly Diagnosed With Ewing Sarcoma Who Have Cancer That Has Spread to Other Parts of the Body
Children's Oncology Group n=437
NCT05411237 NOT YET RECRUITING
Paclitaxel and Pegylated Liposomal Doxorubicin for Treatment of HIV-related Kaposi Sarcoma
AIDS Malignancy Consortium n=130
NCT03422198 RECRUITING
Short Course Vaginal Cuff Brachytherapy in Treating Participants With Stage I-II Endometrial Cancer
University of Utah n=188
NCT01371981 ACTIVE NOT RECRUITING
Bortezomib and Sorafenib Tosylate in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia
National Cancer Institute (NCI) n=1,645
NCT06988475 RECRUITING
DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations
Cancer Research UK n=30
NCT01223248 ACTIVE NOT RECRUITING
Randomized Study Comparing Two Dosing Schedules for Hypofractionated Image-Guided Radiation Therapy
Memorial Sloan Kettering Cancer Center n=220
NCT03805022 RECRUITING
Benefit of Intensified Peri-operative Chemotherapy Within High-risk CINSARC Patients With Resectable Soft-tissue Sarcomas
Institut Bergonié n=351
NCT06263231 ACTIVE NOT RECRUITING
A Study to Investigate Efficacy & Safety of Intratumoral INT230-6 Compared to US Standard of Care in Adults With Soft Tissue Sarcomas (INVINCIBLE-3)
Intensity Therapeutics, Inc. n=333
NCT06332274 RECRUITING
tislelizUMaB in canceR Patients With molEcuLar residuaL Disease
Gustave Roussy, Cancer Campus, Grand Paris n=717
NCT04757337 RECRUITING
Comparison of Oral Cyclophosphamide vs Doxorubicin in ≥65 Years Old Advanced or Metastatic Soft Tissue Sarcoma Patients
UNICANCER n=214
NCT02413736 ACTIVE NOT RECRUITING
Three Versus Five Years of Adjuvant Imatinib as Treatment of Patients With Operable GIST
Heikki Joensuu n=255
NCT04967521 ACTIVE NOT RECRUITING
SARC041: Study of Abemaciclib Versus Placebo in Patients with Advanced Dedifferentiated Liposarcoma
Sarcoma Alliance for Research through Collaboration n=108
NCT06669013 RECRUITING
Chemo-immunotherapy in Patients Under 18 Years of Age With Bone and Soft Tissue Sarcomas
N.N. Petrov National Medical Research Center of Oncology n=40
NCT06480396 NOT YET RECRUITING
High Versus Lower Intensity Surveillance Following Resection of Retroperitoneal Sarcoma
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano n=584
NCT02565498 ACTIVE NOT RECRUITING
Preoperative vs Postoperative IMRT for Extremity/Truncal STS
Mount Sinai Hospital, Canada n=210
NCT05328258 RECRUITING
Use of GnRHa During Chemotherapy for Fertility Protection
Kenny Rodriguez-Wallberg n=500
NCT03784014 COMPLETED
Molecular Profiling of Advanced Soft-tissue Sarcomas
Institut National de la Santé Et de la Recherche Médicale, France n=603
NCT05218499 COMPLETED
Brightline-1: A Study to Compare Brigimadlin (BI 907828) With Doxorubicin in People With a Type of Cancer Called Dedifferentiated Liposarcoma
Boehringer Ingelheim n=400
NCT01231906 COMPLETED
Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma
Children's Oncology Group n=642
NCT06058793 COMPLETED
Brightline-4: A Study to Test How Well Brigimadlin is Tolerated by People With a Type of Cancer Called Dedifferentiated Liposarcoma
Boehringer Ingelheim n=138
NCT02451943 COMPLETED
A Study of Doxorubicin Plus Olaratumab (LY3012207) in Participants With Advanced or Metastatic Soft Tissue Sarcoma
Eli Lilly and Company n=509
NCT05269355 TERMINATED
A Study of Unesbulin in Participants With Advanced Leiomyosarcoma (LMS)
PTC Therapeutics n=359
NCT04979442 TERMINATED
Treatment of Milademetan Versus Trabectedin in Patient With Dedifferentiated Liposarcoma
Rain Oncology Inc n=175
NCT06370871 WITHDRAWN
Brightline-3: A Study to Find Out Whether Brigimadlin in Combination With Ezabenlimab Helps People With Advanced Soft Tissue Sarcoma
Boehringer Ingelheim
NCT04656262 TERMINATED
Low Dose Continuous Cyclophosphamide vs Standard Doxorubicin in Advanced Sarcoma Elderly Patients
Istituto Oncologico Veneto IRCCS n=79
NCT02049905 COMPLETED
Phase 3 Study to Treat Patients With Soft Tissue Sarcomas
ImmunityBio, Inc. n=433
NCT04780464 TERMINATED
A 3 Arm Randomized Study on Health-related QoL of Elderly Patients With Advanced Soft Tissue Sarcoma
European Organisation for Research and Treatment of Cancer - EORTC n=14
NCT05024253 COMPLETED
Perioperative Use of Tranexamic (TXA) in Bone Tumor Surgery Will Change in Blood Loss and Transfusion Requirements.
Children's Cancer Hospital Egypt 57357 n=48
NCT00716976 COMPLETED
Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy
Children's Oncology Group n=131
NCT01327885 COMPLETED
Phase 3 Study to Compare the Efficacy and Safety of Eribulin With Dacarbazine in Subjects With Soft Tissue Sarcoma
Eisai Inc. n=452
NCT03495921 TERMINATED
A Trial For Participants With Ewing's Sarcoma Treated With Vigil in Combination With Irinotecan and Temozolomide
Gradalis, Inc. n=32
NCT00876031 COMPLETED
Trial for Localised High-risk Rhabdomyosarcoma and Rhabdomyosarcoma-like Soft Tissue Sarcoma
University Hospital Tuebingen n=195
NCT02063022 COMPLETED
Efficacy of Dose Intensification in Patients With Non-metastatic Ewing Sarcoma
Italian Sarcoma Group n=278
NCT02997358 COMPLETED
Study Comparing Efficacy of Doxorubicin With Trabectedin Followed by Trabectedin Versus Doxorubicine in Patients With Leiomyosarcoma
Gustave Roussy, Cancer Campus, Grand Paris n=150
NCT01176981 COMPLETED
Outpatient Administration of High Dose Methotrexate (HD MTX) in Patients With Osteosarcoma
The Hospital for Sick Children n=6
NCT02379845 COMPLETED
NBTXR3 Crystalline Nanoparticles and Radiation Therapy in Treating Randomized Patients in Two Arms With Soft Tissue Sarcoma of the Extremity and Trunk Wall
Nanobiotix n=180
NCT01987596 TERMINATED
Study of Fixed vs. Flexible Filgrastim to Accelerate Bone Marrow Recovery After Chemotherapy in Children With Cancer
Barbara Ann Karmanos Cancer Institute n=23
NCT01012297 TERMINATED
Gemcitabine Hydrochloride and Docetaxel With or Without Bevacizumab in Treating Patients With Advanced or Recurrent Uterine Leiomyosarcoma
National Cancer Institute (NCI) n=107
NCT02929394 TERMINATED
Trabectedin Maintenance Post 1st-line in STS
European Organisation for Research and Treatment of Cancer - EORTC n=13
NCT01533207 TERMINATED
Gemcitabine Hydrochloride and Docetaxel Followed by Doxorubicin Hydrochloride or Observation in Treating Patients With High-Risk Uterine Leiomyosarcoma Previously Removed by Surgery
Gynecologic Oncology Group n=38
NCT03520959 TERMINATED
A Phase 3, Randomized, Double-blind, Placebo-controlled Study For Subjects With Locally-advanced Unresectable or Metastatic Synovial Sarcoma (V943-003, IMDZ-04-1702)
Immune Design, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) n=1
NCT01352117 COMPLETED
Antiretroviral Therapy (ART) Alone or With Delayed Chemo Versus ART With Immediate Chemo for Limited AIDS-related Kaposi's Sarcoma
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections n=192
NCT00987636 COMPLETED
Study in Localized and Disseminated Ewing Sarcoma
University Hospital Muenster n=907
NCT03773510 WITHDRAWN
Study on Leiomyosarcoma, Liposarcomas and Synovial Sarcoma With Trabectedin
Italian Sarcoma Group
NCT00870701 TERMINATED
Observation Versus Post-surgery Radiotherapy After Complete Exeresis in Soft Tissues Members Sarcoma
Institut Claudius Regaud n=77
NCT02672527 COMPLETED
Trial Comparing Trabectedin to the Best Supportive Care in Patients With Sarcoma
Gustave Roussy, Cancer Campus, Grand Paris n=103
NCT01692678 COMPLETED
A Study of Trabectedin (YONDELIS) in Patients With Locally Advanced or Metastatic Liposarcoma or Leiomyosarcoma
Xian-Janssen Pharmaceutical Ltd. n=16
NCT02711007 COMPLETED
Apatinib for Advanced Osteosarcoma After Failure of Standard Multimodal Therapy
GUO WEI n=37
NCT01343277 COMPLETED
A Study of Trabectedin or Dacarbazine for the Treatment of Patients With Advanced Liposarcoma or Leiomyosarcoma
Janssen Research & Development, LLC n=579
NCT01440088 COMPLETED
A Trial of TH-302 in Combination With Doxorubicin Versus Doxorubicin Alone to Treat Patients With Locally Advanced Unresectable or Metastatic Soft Tissue Sarcoma
Threshold Pharmaceuticals n=640
NCT01734863 WITHDRAWN
Post-operative Radiotherapy in Poor Responders Ewing's Sarcoma Patients
Children's Cancer Hospital Egypt 57357
NCT00699517 COMPLETED
A Study of AVE8062 in Advanced-stage Soft Tissue Sarcoma After Failure of Anthracycline and Ifosfamide Chemotherapies
Sanofi n=355
NCT00796120 COMPLETED
An Efficacy and Safety Study of Trabectedin Versus Doxorubicin-Based Chemotherapy in Participants With Translocation-Related Sarcomas (TRS)
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. n=121
NCT01189253 TERMINATED
Doxorubicin Hydrochloride or Trabectedin in Treating Patients With Previously Untreated Advanced or Metastatic Soft Tissue Sarcoma
European Organisation for Research and Treatment of Cancer - EORTC n=133
NCT00753688 COMPLETED
Pazopanib Versus Placebo in Patients With Soft Tissue Sarcoma Whose Disease Has Progressed During or Following Prior Therapy
GlaxoSmithKline n=369
NCT01168791 COMPLETED
Study of Palifosfamide-tris in Combination With Doxorubicin in Patients With Front-line Metastatic Soft Tissue Sarcoma
Alaunos Therapeutics n=447
NCT00782145 COMPLETED
A Web-Based Stem Cell Transplant Support System or Standard Care in Young Patients Undergoing Stem Cell Transplant and Their Families
Tufts Medical Center n=198
NCT06498648 RECRUITING
Testing the Addition of an Anti-cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (Gemcitabine) for Soft Tissue Sarcoma
National Cancer Institute (NCI)
NCT05286801 ACTIVE NOT RECRUITING
Tiragolumab and Atezolizumab for the Treatment of Relapsed or Refractory SMARCB1 or SMARCA4 Deficient Tumors
National Cancer Institute (NCI)
NCT03141684 ACTIVE NOT RECRUITING
Testing Atezolizumab Alone or Atezolizumab Plus Bevacizumab in People With Advanced Alveolar Soft Part Sarcoma
National Cancer Institute (NCI)
NCT02923778 ACTIVE NOT RECRUITING
Talimogene Laherparepvec and Radiation Therapy in Treating Patients With Newly Diagnosed Soft Tissue Sarcoma That Can Be Removed by Surgery
National Cancer Institute (NCI)
NCT05333458 RECRUITING
Testing Atezolizumab With Selinexor in People ≥ 12 Years Old With Alveolar Soft Part Sarcoma, The AXIOM Trial
National Cancer Institute (NCI)
NCT03213652 ACTIVE NOT RECRUITING
Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)
National Cancer Institute (NCI)
NCT04595747 ACTIVE NOT RECRUITING
Testing the Anti-cancer Drug, Rogaratinib (BAY 1163877), for Treatment of Advanced Sarcoma With Alteration in Fibroblast Growth Factor Receptor (FGFR 1-4), and in Patients With SDH-deficient Gastrointestinal Stromal Tumor (GIST)
National Cancer Institute (NCI)
NCT04577755 ACTIVE NOT RECRUITING
Pomalidomide Treatment in Patients With Kaposi Sarcoma
National Cancer Institute (NCI)
NCT03972930 ACTIVE NOT RECRUITING
Hypofractionated Radiotherapy for Soft Tissue Sarcomas
University of Wisconsin, Madison
NCT03210714 ACTIVE NOT RECRUITING
Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations (A Pediatric MATCH Treatment Trial)
National Cancer Institute (NCI)
NCT06052618 RECRUITING
Phase II Study of Pacritinib in Kaposi Sarcoma Herpesvirus (KSHV)-Associated Multicentric Castleman Disease and KSHV-Associated Inflammatory Cytokine Syndrome (KICS)
National Cancer Institute (NCI)
NCT05694871 ACTIVE NOT RECRUITING
Testing the Addition of Cemiplimab to Palbociclib for the Treatment of Advanced Dedifferentiated Liposarcoma
Alliance for Clinical Trials in Oncology
NCT04901702 RECRUITING
Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma
St. Jude Children's Research Hospital
NCT07576725 NOT YET RECRUITING
Low Dose, Reduced Frequency Nivolumab for the Treatment of Unresectable or Metastatic Cancer, AFFORD IO Trial
Fred Hutchinson Cancer Center
NCT07308886 RECRUITING
Recombinant Glycosylated Human Interleukin-7 (CYT107) for the Treatment of Kaposi Sarcoma in Participants With HIV and Immune Non-Response (REGIMENKS HIV)
National Cancer Institute (NCI)
NCT07575724 NOT YET RECRUITING
Comparison of the Effects of Needle Biopsy Tract Resection and Non-resection on Recurrence Rate in Patients With Primary Extremity Sarcoma
Second Affiliated Hospital, School of Medicine, Zhejiang University
NCT04941274 RECRUITING
Abemaciclib in Patients With HIV-associated and HIV-negative Kaposi Sarcoma
National Cancer Institute (NCI)
NCT04284774 ACTIVE NOT RECRUITING
Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial
National Cancer Institute (NCI)
NCT03155620 ACTIVE NOT RECRUITING
Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)
National Cancer Institute (NCI)
NCT04851119 RECRUITING
Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors
Children's Oncology Group
NCT04195555 ACTIVE NOT RECRUITING
Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial)
National Cancer Institute (NCI)
NCT06503146 RECRUITING
18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection
National Cancer Institute (NCI)
NCT04320888 ACTIVE NOT RECRUITING
Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial
National Cancer Institute (NCI)
NCT06094101 RECRUITING
Personalized Vaccination in Fusion+ Sarcoma Patients (PerVision)
University Hospital Tuebingen
NCT04200443 ACTIVE NOT RECRUITING
Cabozantinib and Temozolomide for the Treatment of Unresectable or Metastatic Leiomyosarcoma or Other Soft Tissue Sarcoma
City of Hope Medical Center
NCT07560826 NOT YET RECRUITING
The CATSINDO Trial - Clinical and Translational Study in Newly Diagnosed Osteosarcoma
Wake Forest University Health Sciences
NCT06710756 RECRUITING
Lead-212 PSV359 Therapy for Patients With Solid Tumors
Perspective Therapeutics
NCT04303117 RECRUITING
PDS01ADC Monotherapy and in Combination With M7824 in Advanced Kaposi Sarcoma
National Cancer Institute (NCI)
NCT04554914 ACTIVE NOT RECRUITING
A Study to Evaluate Tabelecleucel in Participants With Epstein Barr Virus (EBV) Associated Diseases
Pierre Fabre Medicament
NCT07243626 RECRUITING
Efficacy and Safety of Envafolimab Plus Doxorubicin and Ifosfamide for Advanced Soft Tissue Sarcoma
Second Affiliated Hospital, School of Medicine, Zhejiang University
NCT00840047 ACTIVE NOT RECRUITING
Methionine PET/CT Studies In Patients With Cancer
St. Jude Children's Research Hospital
NCT03414229 ACTIVE NOT RECRUITING
A Study of Epacadostat, an IDO1 Inhibitor, in Combination With Pembrolizumab in Patients With Metastatic and/or Locally Advanced Sarcoma
Memorial Sloan Kettering Cancer Center
NCT03213704 ACTIVE NOT RECRUITING
Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)
National Cancer Institute (NCI)
NCT07428993 RECRUITING
Evaluating Efficacy of B7-H3-CAR T Cells Administered at the End of Upfront Map Chemotherapy in Patients With Newly Diagnosed High-Risk Osteosarcoma
St. Jude Children's Research Hospital
NCT07548177 RECRUITING
Clinical Trials of Benmelstobart Injection Combined With Anlotinib Hydrochloride Capsules in the Treatment of Advanced or Unresectable Alveolar Soft Part Sarcoma
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT03698994 ACTIVE NOT RECRUITING
Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)
National Cancer Institute (NCI)
NCT04332874 RECRUITING
A Study of Pembrolizumab Plus Local Chemotherapy Using Isolated Limb Infusion (ILI) for Patients With Sarcoma in the Arm or Leg
Memorial Sloan Kettering Cancer Center
NCT04968106 ACTIVE NOT RECRUITING
Neoadjuvant Chemotherapy and Retifanlimab in Patients With Selected Sarcomas (TORNADO)
Institut Bergonié
NCT07467772 RECRUITING
Ph 2 Elacestrant in ER Positive Uterine Sarcomas
Dana-Farber Cancer Institute
NCT06975293 RECRUITING
STC-15 as a Part of Combination Therapy With Toripalimab in Selected Advanced Cancers and as Monotherapy in Participants With Selected Sarcomas
STORM Therapeutics LTD
NCT06239272 RECRUITING
NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)
St. Jude Children's Research Hospital
NCT05836571 ACTIVE NOT RECRUITING
Testing Ipilimumab and Nivolumab Combination With or Without Cabozantinib in People >= 18 Years Old With Advanced Soft Tissue Sarcoma
National Cancer Institute LAO
NCT04784247 ACTIVE NOT RECRUITING
Lenvatinib and Pembrolizumab in People With Advanced Soft Tissue Sarcoma
Memorial Sloan Kettering Cancer Center
NCT05969860 RECRUITING
At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer
Mayo Clinic
NCT04028063 ACTIVE NOT RECRUITING
Doxorubicin Plus Dual Checkpoint Blockade for Soft Tissue Sarcomas
University of Colorado, Denver
NCT07539454 NOT YET RECRUITING
Nirogacestat in Patients With Kaposi Sarcoma
AIDS Malignancy Consortium
NCT05019703 RECRUITING
Atezolizumab and Cabozantinib for the Treatment of Adolescents and Young Adults With Recurrent or Metastatic Osteosarcoma, TACOS Study
M.D. Anderson Cancer Center
NCT07283731 RECRUITING
Phase 2 Trial of Zanzalintinib and Pembrolizumab in Select Subtypes of Advanced/Metastatic Soft-tissue Sarcoma
M.D. Anderson Cancer Center
NCT04797767 RECRUITING
Venetoclax and CLAG-M for the Treatment of Acute Myeloid Leukemia and High-Grade Myeloid Neoplasms
University of Washington
NCT02713269 ACTIVE NOT RECRUITING
Thermal Ablation and Spine Stereotactic Radiosurgery in Treating Patients With Spine Metastases at Risk for Compressing the Spinal Cord
M.D. Anderson Cancer Center
NCT01864109 ACTIVE NOT RECRUITING
Irinotecan and Temozolomide in Combination With Existing High Dose Alkylator Based Chemotherapy for Treatment of Patients With Newly Diagnosed Ewing Sarcoma
Memorial Sloan Kettering Cancer Center
NCT06638931 RECRUITING
Agnostic Therapy in Rare Solid Tumors
Instituto do Cancer do Estado de São Paulo
NCT04668300 ACTIVE NOT RECRUITING
Oleclumab and Durvalumab for the Treatment of Recurrent, Refractory, or Metastatic Sarcoma
M.D. Anderson Cancer Center
NCT06607692 RECRUITING
Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).
Fundación de investigación HM
NCT04577014 RECRUITING
Retifanlimab (Anti-PD-1 Antibody) With Gemcitabine and Docetaxel in Patients With Advanced Soft Tissue Sarcoma
Memorial Sloan Kettering Cancer Center
NCT04189783 ACTIVE NOT RECRUITING
Repeat or Single Quadratus Lumborum Block for the Reduction of Opioid Prescriptions After Surgery in Retroperitoneal Sarcoma Patients ("RESQU-SARC" Trial)
M.D. Anderson Cancer Center
NCT06395103 RECRUITING
Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)
Merck Sharp & Dohme LLC
NCT05099666 ACTIVE NOT RECRUITING
Lurbinectedin + Doxorubicin In Leiomyosarcoma
Massachusetts General Hospital
NCT02243605 ACTIVE NOT RECRUITING
Cabozantinib S-malate in Treating Patients With Relapsed Osteosarcoma or Ewing Sarcoma
National Cancer Institute (NCI)
NCT02867592 ACTIVE NOT RECRUITING
Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors
National Cancer Institute (NCI)
NCT06465199 RECRUITING
Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas
Milton S. Hershey Medical Center
NCT05407441 ACTIVE NOT RECRUITING
Tazemetostat+Nivo/Ipi in INI1-Neg/SMARCA4-Def Tumors
Susan Chi, MD
NCT05440786 ACTIVE NOT RECRUITING
CAMPFIRE: A Study of Abemaciclib (LY2835219) in Participants With Ewing's Sarcoma
Eli Lilly and Company
NCT04458922 ACTIVE NOT RECRUITING
Testing Atezolizumab in People 2-17 Years Old With Clear Cell Sarcoma or Advanced Chondrosarcoma
National Cancer Institute (NCI)
NCT06541262 RECRUITING
Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors
Milton S. Hershey Medical Center
NCT07516925 RECRUITING
A Study of Ivonescimab in People With Leiomyosarcoma
Memorial Sloan Kettering Cancer Center
NCT05926700 RECRUITING
Efficacy and Safety of Cadonilimab Plus Anlotinib in Advanced STS That Failed the Previous First-line Standard Treatment
Second Affiliated Hospital, School of Medicine, Zhejiang University
NCT07032285 RECRUITING
Cirtuvivint in Selected Advanced Soft-Tissue Sarcomas
Asociación Europea y Latinoamericana SELNET para la Investigación en Sarcomas
NCT06445166 RECRUITING
Propranolol for the Treatment of Kaposi Sarcoma in Adults
Washington University School of Medicine
NCT03678883 ACTIVE NOT RECRUITING
9-ING-41 in Patients With Advanced Cancers
Actuate Therapeutics Inc.
NCT07507773 NOT YET RECRUITING
Assessment of the Long-term Efficacy of Moderately Hypofractionated Neoadjuvant Radiotherapy Soft Tissue Sarcoma in the Limbs or Trunk Wall
Centre Oscar Lambret
NCT07007273 RECRUITING
Pembrolizumab for Advanced Cutaneous Sarcomas Not Including Angiosarcoma
H. Lee Moffitt Cancer Center and Research Institute
NCT06905132 RECRUITING
Preoperative 5-Day Radiotherapy for Soft Tissue Sarcoma
Medical University of South Carolina
NCT07501026 RECRUITING
Preoperative Spatially Fractionated Radiation Therapy (SFRT) in Soft Tissue Sarcoma (neoSFRT-SARC)
Second Affiliated Hospital, School of Medicine, Zhejiang University
NCT04383119 RECRUITING
Trial in Patients With Metastatic or Locally Advanced Leiomyosarcoma
Italian Sarcoma Group
NCT05395741 ACTIVE NOT RECRUITING
Regorafenib in Patients With Refractory Primary Bone Tumors
Institute of Mother and Child, Warsaw, Poland
NCT01659203 RECRUITING
Proton or Photon RT for Retroperitoneal Sarcomas
Massachusetts General Hospital
NCT07479732 RECRUITING
Apatinib Combined With Liposomal Irinotecan for Refractory or Metastatic Osteosarcoma
Peking University People's Hospital
NCT07477457 RECRUITING
A Study of Gefitinib, Trametinib, Disulfiram, and Sunitinib in Addition to Standard Chemotherapy in People With Osteosarcoma
Memorial Sloan Kettering Cancer Center
NCT03965234 RECRUITING
Pulmonary Suffusion in Controlling Minimal Residual Disease in Patients With Sarcoma or Colorectal Metastases
Roswell Park Cancer Institute
NCT06843967 RECRUITING
A Study of Mirdametinib in Combination With Palbociclib in People With Liposarcoma
Memorial Sloan Kettering Cancer Center
NCT05755113 RECRUITING
A Clinical Study to Investigate the Efficacy of Intratumoral Tigilanol Tiglate in Soft Tissue Sarcoma
QBiotics Group Limited
NCT06625190 RECRUITING
Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors
University of Florida
NCT07076186 RECRUITING
Phase II Decentralized Pragmatic Trial of Adjuvant Doxorubicin - Trabectedin Chemotherapy in uLMS
M.D. Anderson Cancer Center
NCT07460986 NOT YET RECRUITING
A PHASE IB/II STUDY TO EVALUATE SAFETY AND EFFICACY OF BEXMARILIMAB IN COMBINATION WITH DOXORUBICIN IN METASTATIC SOFT-TISSUE SARCOMA
MedSIR
NCT07457775 NOT YET RECRUITING
Liposomal Irinotecan in Combination With Temozolomide and Bevacizumab in Patients With Advanced STS
Second Affiliated Hospital, School of Medicine, Zhejiang University
NCT05660408 ACTIVE NOT RECRUITING
RNA Lipid Particles Targeting Pediatric Recurrent Intracranial Malignancies and Other systEmic Solid Tumors
University of Florida
NCT07291297 RECRUITING
Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma
Wake Forest University Health Sciences
NCT06416085 ACTIVE NOT RECRUITING
Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Patients With Advanced Cancer
University Health Network, Toronto
NCT04751409 RECRUITING
Evaluating the Impact of Limited Compared With Intense Post-Operative Surveillance on Patient-Reported Outcomes in Patients With Stage II-III Soft Tissue Sarcoma of the Trunk and Extremities
M.D. Anderson Cancer Center
NCT03307616 ACTIVE NOT RECRUITING
Nivolumab With and Without Ipilimumab and Radiation Therapy in Treating Patients With Recurrent or Resectable Undifferentiated Pleomorphic Sarcoma or Dedifferentiated Liposarcoma Before Surgery
M.D. Anderson Cancer Center
NCT03819985 ACTIVE NOT RECRUITING
Shorter Course, Hypofractionated Pre-Surgery Radiation Therapy in Treating Patients With Localized, Resectable Soft Tissue Sarcoma of the Extremity of Superficial Trunk
M.D. Anderson Cancer Center
NCT05703854 RECRUITING
Study of CAR.70-engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Advanced Renal Cell Carcinoma, Mesothelioma and Osteosarcoma
M.D. Anderson Cancer Center
NCT07447050 RECRUITING
Riluzole For Preventing Cognitive Dysfunction in Ca Pts Receiving Chemo (REFOCUS): Pilot Trial
University of California, Irvine
NCT04771520 RECRUITING
Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors
M.D. Anderson Cancer Center
NCT04417062 ACTIVE NOT RECRUITING
Olaparib With Ceralasertib in Recurrent Osteosarcoma
Dana-Farber Cancer Institute
NCT01946529 ACTIVE NOT RECRUITING
Therapeutic Trial for Patients With Ewing Sarcoma Family of Tumor and Desmoplastic Small Round Cell Tumors
St. Jude Children's Research Hospital
NCT04288375 ACTIVE NOT RECRUITING
Dose Reduction of Postoperative Radiation for Soft Tissue Sarcoma of the Arms and Legs
Memorial Sloan Kettering Cancer Center
NCT06709495 RECRUITING
Phase 1/2 Trial to Evaluate the Safety and Efficacy of PEEL-224 in Combination With Vincristine and Temozolomide in Adolescents and Young Adults With Relapsed or Refractory Sarcomas
David S Shulman, MD
NCT07410676 RECRUITING
EBNK-001 Allogeneic NK Cells With Low-Dose IL-15 ± Pembrolizumab in Advanced Solid Tumors
Essen Biotech
NCT04698785 RECRUITING
Efficacy of Regorafenib Combined With Best Supportive Care as Maintenance Treatment in High Grade Bone Sarcomas Patients
Centre Leon Berard
NCT03624244 RECRUITING
Evaluation of Clinical Impact of Interruption VS Maintenance of AI in Patients With Locally Advanced/ Metastatic Low Grade Endometrial Stromal Sarcoma (LGESS)
Centre Leon Berard
NCT05253131 NOT YET RECRUITING
Trial of Selumetinib and Bromodomain Inhibitor With Durvalumab for Sarcomas
University of Alabama at Birmingham
NCT05726383 RECRUITING
Iscador® P (Mistletoe) Immunotherapy for Recurrent Osteogenic Sarcoma
Hackensack Meridian Health
NCT03474094 ACTIVE NOT RECRUITING
Clinical and Biological Activity of an Anti-PD-L1 (Atezolizumab) in Operable Localised Soft Tissue Sarcomas Patients to be Treated With Radiotherapy
Centre Leon Berard
NCT05180695 ACTIVE NOT RECRUITING
HDM201 and Pazopanib in Patients With P53 Wild-type Advanced/Metastatic Soft Tissue Sarcomas
Centre Leon Berard
NCT06712433 NOT YET RECRUITING
Bacterial Decolonization Plus Intraoperative Angiography for Soft Tissue Sarcomas Receiving Preoperative Radiotherapy (CONCERTO)
Adam Olson
NCT03851614 ACTIVE NOT RECRUITING
Study of DNA Damage, Angiogenesis, and PD-L1 Inhibitors in Advanced Solid Tumors
University Health Network, Toronto
NCT04044768 ACTIVE NOT RECRUITING
Spearhead 1 Study in Subjects With Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma
USWM CT, LLC
NCT07125183 RECRUITING
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
University of Colorado, Denver
NCT03465592 RECRUITING
Trial of Nivolumab Following Partially Human Leukocyte Antigen (HLA) Mismatched BMT in Children & Adults With Sarcoma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT03598595 ACTIVE NOT RECRUITING
Gemcitabine, Docetaxel, and Hydroxychloroquine in Treating Participants With Recurrent or Refractory Osteosarcoma
M.D. Anderson Cancer Center
NCT04562480 ACTIVE NOT RECRUITING
Radiation Therapy Before Surgery for Localized, Resectable Soft Tissue Sarcoma of the Extremity and Superficial Trunk
Mayo Clinic
NCT05734066 RECRUITING
Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing Sarcoma
Jazz Pharmaceuticals
NCT04390737 RECRUITING
Evaluate the Safety and Clinical Activity of HH2853
Haihe Biopharma Co., Ltd.
NCT05634369 RECRUITING
A Multi-Institution Study of TGFβ Imprinted, Ex Vivo Expanded Universal Donor NK Cell Infusions as Adoptive Immunotherapy in Combination With Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Pediatric Bone and Soft Tissue
Nationwide Children's Hospital
NCT05109494 RECRUITING
Hypofractionated vs Conventional Fractionated RT in Soft Tissue Sarcomas
University of Wisconsin, Madison
NCT07173972 RECRUITING
Dose-escalated, Hypofractionated, Definitive Proton Radiotherapy for Patients With Inoperable Soft Tissue Sarcoma.
Oslo University Hospital
NCT07169344 RECRUITING
Hypofractionated, 3-week, Preoperative Proton or X-ray Radiotherapy for Patients With Localized Soft Tissue Sarcoma
Oslo University Hospital
NCT05797662 NOT YET RECRUITING
A Study of Propranolol to Treat Kaposi Sarcoma
AIDS Malignancy Consortium
NCT05071209 ACTIVE NOT RECRUITING
Elimusertib for the Treatment of Relapsed or Refractory Solid Tumors
National Cancer Institute (NCI)
NCT07359053 RECRUITING
MAGNATE-S: Paclitaxel Polymer Micelles Combo in Advanced Sarcoma
Shanghai 6th People's Hospital
NCT06981637 RECRUITING
Pegylated Liposomal Doxorubicin (PLD) Versus Active Surveillance for Advanced Soft Tissue Sarcoma Patients Who Had Controlled Disease After Standard Anthracycline-based Treatment (MELODY)
National Health Research Institutes, Taiwan
NCT06660810 ACTIVE NOT RECRUITING
Neoadjuvant Intralesional Injection of Talimogene Laherparepvec
John Rieth
NCT07342322 NOT YET RECRUITING
A Prospective, Multicenter, Open-label, Single-arm Phase II Clinical Study Evaluating the Efficacy and Safety of Spatially Fractionated Radiotherapy Combined With the PraG Strategy for the Treatment of Soft Tissue Sarcoma
First Affiliated Hospital of Guangxi Medical University
NCT06571734 RECRUITING
XL092 (Zanzalintinib) for the Treatment of Patients With Metastatic or Unresectable Leiomyosarcoma
Northwestern University
NCT07321912 NOT YET RECRUITING
Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma
Milton S. Hershey Medical Center
NCT06849986 RECRUITING
IO Combined With AI as First-line Treatment for Patients With Soft Tissue Sarcoma(TAIS)
Fudan University
NCT03899792 ACTIVE NOT RECRUITING
A Study of Oral LOXO-292 (Selpercatinib) in Pediatric Participants With Advanced Solid or Primary Central Nervous System (CNS) Tumors
Eli Lilly and Company
NCT06835049 RECRUITING
Feasibility of Total Neoadjuvant Treatment With HYPErthermia in Patients With High-risk Extremity and Trunk Soft Tissue Sarcoma (TNT-HYPE)
Swiss Cancer Institute
NCT06942442 RECRUITING
A Phase II Trial of Tebentafusp in HLA-A*02:01 Positive Patients With Advanced Clear Cell Sarcoma
Sarcoma Alliance for Research through Collaboration
NCT03643133 ACTIVE NOT RECRUITING
Mifamurtide Combined With Post-operative Chemotherapy for Newly Diagnosed High Risk Osteosarcoma Patients
UNICANCER
NCT07192068 RECRUITING
Clinical Trial Evaluating the Activity of Zanidatamab for the Treatment of Patients With Solid Tumors With an Alteration of the HER2 Gene.
UNICANCER
NCT04416568 ACTIVE NOT RECRUITING
Study of Nivolumab and Ipilimumab in Children and Young Adults With INI1-Negative Cancers
Dana-Farber Cancer Institute
NCT07089992 RECRUITING
A Study of Pembrolizumab in People With Ultra-Rare Sarcomas
Memorial Sloan Kettering Cancer Center
NCT06943521 RECRUITING
A Study of MT-4561 in Patients With Various Advanced Solid Tumors
Tanabe Pharma America, Inc.
NCT05167994 RECRUITING
Preoperative IMRT With Concurrent Anlotinib for Localised Extremity or Trunk Sarcoma （SPARE-01）
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT02523040 ACTIVE NOT RECRUITING
Lenalidomide for Adult Histiocyte Disorders
Dana-Farber Cancer Institute
NCT06128863 ACTIVE NOT RECRUITING
Pembrolizumab in Combination With Eftilagimod Alpha and Radiotherapy in Neoadjuvant Treatment of Patients With Soft Tissue Sarcoma - EFTISARC-NEO Trial
Maria Sklodowska-Curie National Research Institute of Oncology
NCT05120271 ACTIVE NOT RECRUITING
BOXR1030 T Cells in Subjects With Advanced GPC3-Positive Solid Tumors
Sotio Biotech Inc.
NCT05301283 RECRUITING
Habitat Escalated Adaptive Therapy (HEAT), With Neoadjuvant Radiation for Soft Tissue Sarcoma
H. Lee Moffitt Cancer Center and Research Institute
NCT03880019 ACTIVE NOT RECRUITING
A Phase II Clinical Trial Evaluating the Combination of Olaparib and Temozolomide for the Treatment of Advanced Uterine Leiomyosarcoma
National Cancer Institute (NCI)
NCT06333314 RECRUITING
Dostarlimab for Locally Advanced or Metastatic Cancer (Non-colorectal/Non-endometrial) With Tumor dMMR/MSI
UNICANCER
NCT04727242 ACTIVE NOT RECRUITING
CytoreductiveSurgery & HIPEC w/Gemcitabine+Chemotherapy w/Dacarbazine in Uterine Leiomyosarcoma
Stanford University
NCT03449108 ACTIVE NOT RECRUITING
LN-145 or LN-145-S1 in Treating Patients With Relapsed or Refractory Ovarian Cancer, Triple Negative Breast Cancer (TNBC), Anaplastic Thyroid Cancer, Osteosarcoma, or Other Bone and Soft Tissue Sarcomas
M.D. Anderson Cancer Center
NCT03589729 RECRUITING
Dexrazoxane Hydrochloride in Preventing Heart-Related Side Effects of Chemotherapy in Participants With Blood Cancers
M.D. Anderson Cancer Center
NCT04624178 ACTIVE NOT RECRUITING
A Study of Rucaparib and Nivolumab in People With Leiomyosarcoma
Memorial Sloan Kettering Cancer Center
NCT07049848 RECRUITING
SATURN-STS: Phase II Study of Neoadjuvant Atezolizumab With Doxorubicin, Concurrent Atezolizumab With Pre-operative Radiation Therapy and Adjuvant Atezolizumab in Patients With High-risk Surgically Resectable Extremity and Truncal Soft Tissue Sarcoma
M.D. Anderson Cancer Center
NCT06521567 ACTIVE NOT RECRUITING
A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer
GlaxoSmithKline
NCT04551430 ACTIVE NOT RECRUITING
Cabozantinib Combined With PD-1 and CTLA-4 Inhibition in Metastatic Soft Tissue Sarcoma
Washington University School of Medicine
NCT04803877 ACTIVE NOT RECRUITING
SARC038: Phase 2 Study of Regorafenib and Nivolumab in Osteosarcoma
Sarcoma Alliance for Research through Collaboration
NCT03069378 ACTIVE NOT RECRUITING
A Study of Talimogene Laherparepvec (T-VEC) in Combination With Pembrolizumab in Patients With Metastatic and/or Locally Advanced Sarcoma
Memorial Sloan Kettering Cancer Center
NCT05886634 ACTIVE NOT RECRUITING
A Study of Etrumadenant and Zimberelimab in People With Dedifferentiated Liposarcoma
Memorial Sloan Kettering Cancer Center
NCT06327477 RECRUITING
Proton-Spatially Fractionated Radiotherapy and Standard Radiation Therapy for the Treatment of Newly Diagnosed Retroperitoneal Soft Tissue Sarcoma
Northwestern University
NCT05515575 ACTIVE NOT RECRUITING
A Study of Niraparib in People With Soft Tissue Sarcoma Who Have Changes in Their Tumor DNA
Memorial Sloan Kettering Cancer Center
NCT04438824 ACTIVE NOT RECRUITING
Palbociclib and INCMGA00012 in People With Advanced Liposarcoma
Memorial Sloan Kettering Cancer Center
NCT04370587 RECRUITING
A Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors
ImmVira Pharma Co. Ltd
NCT05182164 RECRUITING
Combination of Pembrolizumab and Cabozantinib in Patients With Advanced Sarcomas
Institut Bergonié
NCT02502786 ACTIVE NOT RECRUITING
Humanized Monoclonal Antibody 3F8 (Hu3F8) With Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) in the Treatment of Recurrent Osteosarcoma
Memorial Sloan Kettering Cancer Center
NCT07205185 NOT YET RECRUITING
A Multicenter, Single-arm, Prospective Phase II Clinical Study of Epalrotokewali Combined With Eribulin, Anlotinib, and Radiotherapy for the Treatment of Patients With Advanced Soft Tissue Sarcoma.
Fudan University
NCT05296564 RECRUITING
Anti-NY-ESO-1 TCR-Gene Engineered Lymphocytes Given by Infusion to Patients With NY-ESO-1 -Expressing Metastatic Cancers
Hadassah Medical Organization
NCT04557449 ACTIVE NOT RECRUITING
Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors
Pfizer
NCT03282344 ACTIVE NOT RECRUITING
A Study of NKTR-214 in Combination With Nivolumab in Patients With Metastatic and/or Locally Advanced Sarcoma
Memorial Sloan Kettering Cancer Center
NCT06528769 RECRUITING
Study of All-Trans Retinoic Acid (ATRA) and Cemiplimab in Patients With Advanced Leiomyosarcoma
Gabriel Tinoco
NCT07153887 RECRUITING
Vebreltinib for Advanced or Metastatic CCS
Second Affiliated Hospital, School of Medicine, Zhejiang University
NCT04273061 RECRUITING
Investigating the Effects of Atezolizumab in People Whose Tumour DNA or RNA Indicates Possible Sensitivity
British Columbia Cancer Agency
NCT04079179 RECRUITING
Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders
Carl Allen
NCT02389244 ACTIVE NOT RECRUITING
A Phase II Study Evaluating Efficacy and Safety of Regorafenib in Patients With Metastatic Bone Sarcomas
UNICANCER
NCT04515459 RECRUITING
Efficacy of Pre-operative Prehabilitation in Patients With Limb Sarcoma
Institut Claudius Regaud
NCT07014137 RECRUITING
A Trial of ABSK043, an Oral PD-L1 Inhibitor, in Patients With Angiogenic Sarcomas
University Health Network, Toronto
NCT07156643 NOT YET RECRUITING
A Prospective, Single-arm, Multicenter Exploratory Clinical Study of Anlotinib Combined With Bempegaldesleukin and Conventional Chemoradiotherapy for the Treatment of Unresectable Locally Advanced or Metastatic Soft Tissue Sarcoma.
The First Affiliated Hospital with Nanjing Medical University
NCT06389799 RECRUITING
A Phase 2, Open Label Study of PEmigatinib and REtifanlimab in Advanced Dedifferentiated LIposarcoma (PERELI)
Lund University Hospital
NCT07142863 NOT YET RECRUITING
Envafolimab Combined With Neoadjuvant Chemotherapy Treat Stage IIb Resectable Osteosarcoma Patients
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
NCT05864144 ACTIVE NOT RECRUITING
A Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors
Sensei Biotherapeutics, Inc.
NCT04776525 RECRUITING
Sequential Neoadjuvant Chemotherapy in Soft Tissue Sarcoma
Oslo University Hospital
NCT04874311 RECRUITING
Bintrafusp Alfa and Doxorubicin Hydrochloride in Treating Patients With Advanced Sarcoma
Institut Bergonié
NCT06298916 RECRUITING
64Cu-LNTH-1363S in Patients With Sarcoma or Gastrointestinal Tract Cancer
Lantheus Medical Imaging
NCT05135975 RECRUITING
A Study of Cabozantinib as a Maintenance Agent to Prevent Progression or Recurrence in High-Risk Pediatric Solid Tumors
Nationwide Children's Hospital
NCT02790515 ACTIVE NOT RECRUITING
Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior Transplantation
St. Jude Children's Research Hospital
NCT07092306 NOT YET RECRUITING
A Randomized Controlled Study Comparing the Safety and Efficacy of Irinotecan Hydrochloride Liposome Injection Combined With Temozolomide and Vincristine (NALIRI-VT) Versus Irinotecan Combined With Temozolomide and Vincristine (VIT) in Patients With Advanced Ewing's Sarcoma
Tang Xiaodong
NCT06277154 RECRUITING
MASCT-I Combined With Doxorubicin and Ifosfamide for First-line Treatment of Advanced Soft Tissue Sarcoma
HRYZ Biotech Co.
NCT04040205 RECRUITING
Abemaciclib for Bone and Soft Tissue Sarcoma With Cyclin-Dependent Kinase (CDK) Pathway Alteration
Medical College of Wisconsin
NCT06367075 RECRUITING
A Trial of Cadonilimab With Adriamycin in Patients With Advanced Soft Tissue Sarcoma
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
NCT07067255 RECRUITING
Sequential CD146 and GPC3 CAR-T Cell Therapy in Advanced Ovarian Cancer
Essen Biotech
NCT05679921 RECRUITING
Pazopanib With or Without Pembrolizumab for Metastatic Soft Tissue Sarcoma
Yonsei University
NCT07066982 RECRUITING
Sequential Infusion of CD146-Targeted and HER2-Targeted CAR T Cells in Patients With Advanced Sarcomas
Essen Biotech
NCT07064018 RECRUITING
Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies
University of California, Irvine
NCT03935893 RECRUITING
Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers
Udai Kammula
NCT07028086 RECRUITING
VAM in Secondary AML, AML With Extramedullary Involvement, and Myeloid Sarcoma
Ruijin Hospital
NCT07048184 NOT YET RECRUITING
Sarcoma Surgery Wound Complications Comparing Usual Versus Negative Pressure Dressing
NHS Greater Glasgow and Clyde
NCT06580002 RECRUITING
Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial
University of California, Irvine
NCT06114004 RECRUITING
Selinexor Plus Gemcitabine in Selected Advanced Soft-tissue Sarcoma (SeliSarc)
Asociación Europea y Latinoamericana SELNET para la Investigación en Sarcomas
NCT02650986 ACTIVE NOT RECRUITING
Gene-Modified T Cells With or Without Decitabine in Treating Patients With Advanced Malignancies Expressing NY-ESO-1
Roswell Park Cancer Institute
NCT06022159 RECRUITING
A Study to Evaluate Pre-operative HYPOfractionated Radiation Therapy in Aged (≥ 70 Years Old) or "Fragile" (≥ 65 Years) Patients With Limb or Trunk Soft Tissue SARComa.
Institut Claudius Regaud
NCT02846987 ACTIVE NOT RECRUITING
Study of Abemaciclib in Dedifferentiated Liposarcoma
Memorial Sloan Kettering Cancer Center
NCT06827717 RECRUITING
Phase II Study of Irinotecan Liposome (II) Combined With Temozolomide and Fluzoparib in Recurrent or Metastatic Ewing Sarcoma
Sun Yat-sen University
NCT04072042 RECRUITING
BIOmarker Driven Trial of VEGFR2 Inhibitor in Advanced or Metastatic Sarcoma
Ruijin Hospital
NCT05894018 RECRUITING
Brachytherapy (Iodine-125 Seeds) and Fluzoparib Combination Therapy for Advanced Unresectable Soft Tissue Sarcoma
Fujun Zhang
NCT06892678 RECRUITING
DFMO Maintenance for Patients With Relapsed/Refractory Ewing Sarcoma or Osteosarcoma
Montefiore Medical Center
NCT05968768 RECRUITING
To Evaluate the Efficacy and Safety of Naxitamab in Patients With Refractory Ewing's Sarcoma (Butterfly)
Anna Raciborska
NCT05588648 RECRUITING
Study to Assess Safety and Efficacy of Vactosertib in Adolescents and Adults With Recurrent, Refractory or Progressive Osteosarcoma
MedPacto, Inc.
NCT03114527 ACTIVE NOT RECRUITING
Phase II Trial of Ribociclib and Everolimus in Advanced Dedifferentiated Liposarcoma (DDL) and Leiomyosarcoma (LMS)
Fox Chase Cancer Center
NCT06524583 RECRUITING
Interest of Post-operative Chemotherapy in Patients With Localised Uterine Leiomyosarcoma Suspected of Having a High Risk of Recurrence Based on a Biological Test Performed on the Tumour
UNICANCER
NCT05809830 ACTIVE NOT RECRUITING
Phase I/II of LB-100 Plus Doxorubicin vs. Doxorubicin Alone in First Line of Advanced Soft Tissue Sarcomas
Grupo Espanol de Investigacion en Sarcomas
NCT04802876 ACTIVE NOT RECRUITING
Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients with PD1-high MRNA Expressing Tumors
SOLTI Breast Cancer Research Group
NCT05146440 RECRUITING
Multicohort Trial of Different Schemes of PM14 in Monotherapy and in Combination with Radiotherapy in Soft Tissue Sarcomas and Other Solid Tumor
Grupo Espanol de Investigacion en Sarcomas
NCT04785196 RECRUITING
APG-115 in Combination With PD-1 Inhibitor in Patients With Advanced Liposarcoma or Advanced Solid Tumors
Ascentage Pharma Group Inc.
NCT04165330 ACTIVE NOT RECRUITING
Evaluation of AL3818 in Combination With Nivolumab in Solid Tumors
Sarcoma Oncology Research Center, LLC
NCT04535271 RECRUITING
Metronomic Trabectedin, Gemcitabine, and Dacarbazine for Soft Tissue Sarcoma
Sarcoma Oncology Research Center, LLC
NCT03138161 RECRUITING
SAINT:Trabectedin, Ipilimumab and Nivolumab for Previously Treated Advanced Soft Tissue Sarcoma
Sarcoma Oncology Research Center, LLC
NCT03886311 RECRUITING
Talimogene Laherparepvec, Nivolumab and Trabectedin for Sarcoma
Sarcoma Oncology Research Center, LLC
NCT03778996 ACTIVE NOT RECRUITING
SM-88 Maintenance Therapy for Advanced Ewing's Sarcoma and as Salvage Therapy for Sarcoma
Sarcoma Oncology Research Center, LLC
NCT03548428 RECRUITING
Stereotaxic Body Irradiation of Oligometastase in Sarcoma (Stereosarc)
Centre Antoine Lacassagne
NCT03373097 ACTIVE NOT RECRUITING
Anti-GD2 CAR T Cells in Pediatric Patients Affected by High Risk and/or Relapsed/Refractory Neuroblastoma or Other GD2-positive Solid Tumors
Bambino Gesù Hospital and Research Institute
NCT06476704 NOT YET RECRUITING
Study of Preoperative RAdiation Therapy With Concomitant Liposomal Transcrocetin (L-TC) in Soft tISsue Sarcomas
Institut de cancérologie Strasbourg Europe
NCT04733183 ACTIVE NOT RECRUITING
Efficacy and Safety of L19TNF in Previously Treated Patients with Advanced Stage or Metastatic Soft-tissue Sarcoma
Philogen S.p.A.
NCT06778603 RECRUITING
B7-H3 NIR Imaging for Osteosarcoma Surgery
Peking University People's Hospital
NCT03709680 ACTIVE NOT RECRUITING
Study Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid Tumors
Pfizer
NCT06456359 RECRUITING
Pasireotide as Maintenance Treatment in Synovial Sarcoma and Desmoplastic Small Round Cell Tumor
University Hospital Heidelberg
NCT06650514 RECRUITING
A Phase 2 Pilot Study to Evaluate the Safety and the Anti-Tumour Activity of the Myc Inhibitor OMO-103 Administered Intravenously in Patients With Advanced High-Grade Osteosarcoma
Vall d'Hebron Institute of Oncology
NCT05688280 ACTIVE NOT RECRUITING
Intratumoral Injection of IP-001 Following Thermal Ablation in Patients With CRC, NSCLC, and STS
Immunophotonics, Inc.
NCT06126510 RECRUITING
Clinical Study of VG161 in the Treatment of Advanced Bone and Soft Tissue Sarcoma
CNBG-Virogin Biotech (Shanghai) Ltd.
NCT06714383 RECRUITING
Trilaciclib Combing Chemotherapy in the Neoadjuvant Treatment of Osteosarcoma
Peking University People's Hospital
NCT05824975 RECRUITING
A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08)
GI Innovation, Inc.
NCT06699472 RECRUITING
A Prospective, Randomized, Controlled Clinical Study on the Prevention of Chemotherapy Related Myelosuppression in Patients with Ewing's Sarcoma Using Trilaciclib
Fudan University
NCT02203760 ACTIVE NOT RECRUITING
Pazopanib Vs. Pazopanib Plus Gemcitabine
North Eastern German Society of Gynaecological Oncology
NCT04673942 RECRUITING
A Study of AdAPT-001 in Subjects With Sarcoma and Refractory Solid Tumors
EpicentRx, Inc.
NCT06637007 RECRUITING
Phase II Clinical Trial of Chidamide Combined With AK112 for Second-line and Advanced Bone and Soft Tissue Sarcoma
Shanxi Province Cancer Hospital
NCT04166006 RECRUITING
A Phase II Study on Adjuvant Vaccination with Dendritic Cells Loaded with Autologous Tumor Homogenate in Resected Stage IV Rare Cancers.
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
NCT05830123 RECRUITING
ARTEMIS-002: HS-20093 in Patients With Relapsed or Refractory Osteosarcoma and Other Sarcomas
Hansoh BioMedical R&D Company
NCT06564272 RECRUITING
A Study of KC1036 in Adolescents With Advanced Ewing Sarcoma
Beijing Konruns Pharmaceutical Co., Ltd.
NCT06551896 NOT YET RECRUITING
Pemigatinib and Immune Checkpoint Inhibitor Treated FGFR1/2/3 Alteration Advanced Solid Tumor
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
NCT06524778 NOT YET RECRUITING
Single High-dose Brachytherapy for Giant Osteosarcoma Masses
Shanghai Jiao Tong University Affiliated Sixth People's Hospital
NCT06514313 RECRUITING
Clinical Trial of VIM With VIT in Children With Relapsed and Refractory Soft Tissue Sarcoma.
Yizhuo Zhang
NCT06500091 NOT YET RECRUITING
TQB2916 Injection Combined With Chemotherapy or Penpulimab Injection in the Treatment of Solid Tumors
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT04535713 RECRUITING
GALLANT: Metronomic Gemcitabine, Doxorubicin, Docetaxel and Nivolumab for Advanced Sarcoma
Sarcoma Oncology Research Center, LLC
NCT05876715 RECRUITING
LINNOVATE: Lurbinectedin, Ipilimumab and Nivolumab for Soft Tissue Sarcoma
ERLINDA M GORDON
NCT01898663 RECRUITING
DCs Vaccine Combined With Cytokine-induced Killer Cells in Patients With AML
Affiliated Hospital to Academy of Military Medical Sciences
NCT05187338 RECRUITING
Triplex Checkpoint Inhibitors Therapy for Advanced Solid Tumors
Second Affiliated Hospital of Guangzhou Medical University
NCT05955105 RECRUITING
A Study of ILB2109 and Toripalimab in Patients With Advanced Solid Malignancies
Innolake Biopharm
NCT04480502 ACTIVE NOT RECRUITING
ENVASARC: Envafolimab And Envafolimab With Ipilimumab In Patients With Undifferentiated Pleomorphic Sarcoma Or Myxofibrosarcoma
Tracon Pharmaceuticals Inc.
NCT05396118 ENROLLING BY INVITATION
Simultaneous Hyperpolarized [1-13C]Pyruvate and 18F-FDG PET/MRS in Cancer Patients
Rigshospitalet, Denmark
NCT05926492 RECRUITING
A Clinical Study of Surufatinib Combined With Chemotherapy as Neoadjuvant Treatment in Osteosarcoma
Second Affiliated Hospital, School of Medicine, Zhejiang University
NCT04889742 NOT YET RECRUITING
Hyperthermia Enhanced Re-irradiation of Loco-regional Recurrent Tumors
Charite University, Berlin, Germany
NCT03092323 ACTIVE NOT RECRUITING
A Randomized Trial of Pembrolizumab & Radiotherapy Versus Radiotherapy in High-Risk Soft Tissue Sarcoma of the Extremity
Sarcoma Alliance for Research through Collaboration
NCT06114225 RECRUITING
Pulmonary Resectable Osteosarcoma Treated by Metastasectomy and Pre-operative Immunotherapy and Stereotactic Body Radiotherapy (PROMIS): a Prospective Clinical Trial
Ruijin Hospital
NCT06074692 RECRUITING
PARP Inhibition, Stereotactic Body Radiotherapy and Immunotherapy for Metastatic or Advanced Sarcoma (PRIMA)
Ruijin Hospital
NCT06041490 NOT YET RECRUITING
Adjuvant Therapy for High-risk Hepatocellular Carcinoma Post Liver Transplantation
Peking Union Medical College Hospital
NCT05839275 RECRUITING
The Combination of Radiotherapy，Surufatinib and Sintilimab in High-Risk Localized Soft Tissue Sarcoma
Fudan University
NCT04758000 RECRUITING
Metformin as Maintenance Therapy in Patients With Bone Sarcoma and High Risk of Relapse
Istituto Ortopedico Rizzoli
NCT05961761 RECRUITING
Propranolol and Pembrolizumab in Advanced Soft Tissue Sarcoma Patients
Niels Junker
NCT02275286 RECRUITING
Trabectedin Plus Radiotherapy in Soft Tissue Sarcoma Patients
Grupo Espanol de Investigacion en Sarcomas
NCT05774275 RECRUITING
The Combination of Radiotherapy, Chemotherapy and Immunotherapy in High-Risk Localized Soft Tissue Sarcoma
Fudan University
NCT05722977 NOT YET RECRUITING
Surufatinib and Envafolimab as Second or More-line Therapy in Advanced Soft Tissue Sarcoma Patients
Peking Union Medical College Hospital
NCT05590572 NOT YET RECRUITING
A Study of Sulfatinib on Relapsed or Refractory Drug Resistant Osteosarcoma
Second Affiliated Hospital, School of Medicine, Zhejiang University
NCT04616560 SUSPENDED
Trastuzumab Deruxtecan for the Treatment of HER2+ Newly Diagnosed or Recurrent Osteosarcoma
National Cancer Institute (NCI)
NCT04902872 COMPLETED
Study of CBX-12 in Subjects With Advanced or Metastatic Refractory Solid Tumors
Cybrexa Therapeutics
NCT03802071 COMPLETED
A Study of Durvalumab in Combination With Doxorubicin for Advanced Soft Tissue Sarcoma
Yonsei University
NCT06630325 TERMINATED
A Precision Medicine Approach (SMMART-ACT) for the Treatment of Patients With Advanced Sarcoma, Prostate, Breast, Ovarian or Pancreatic Cancer
OHSU Knight Cancer Institute
NCT04216953 COMPLETED
MEK Inhibitor and a PDL1 Inhibitor Patients With Locally Advanced and/or Metastatic Soft Tissue Sarcoma
Centre Leon Berard
NCT04095208 COMPLETED
Combination of Nivolumab Plus Relatlimab in Patients With Advanced or Metastatic Soft-tissue Sarcoma: a Proof-of-concept Randomized Phase II Study
Institut Bergonié
NCT03213678 COMPLETED
Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial)
National Cancer Institute (NCI)
NCT05879185 TERMINATED
A Study of XmAb23104 in People With Sarcoma
Memorial Sloan Kettering Cancer Center
NCT03601806 COMPLETED
Pomalidomide in Treating Patients With Kaposi Sarcoma and Human Immunodeficiency Virus Infection
AIDS Malignancy Consortium
NCT03213665 COMPLETED
Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)
National Cancer Institute (NCI)
NCT03526250 COMPLETED
Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)
National Cancer Institute (NCI)
NCT02945800 COMPLETED
Nab-Paclitaxel and Gemcitabine for Recurrent/Refractory Sarcoma
H. Lee Moffitt Cancer Center and Research Institute
NCT06341712 TERMINATED
Effects of Maintenance Cabozantinib+BSC Versus BSC in Children and AYA With Osteosarcoma
Ipsen
NCT05046314 COMPLETED
A Clinical Study of TK216 in Patients With Relapsed or Refractory Ewing's Sarcoma
Shanghai Pharmaceuticals Holding Co., Ltd
NCT01303094 COMPLETED
Continuing vs Intermittent Trabectedin in Patients With Advanced Soft Tissue Sarcoma
Centre Oscar Lambret
NCT01612481 TERMINATED
Phase II Study Evaluating Strategies of Lung Surveillance of Patients Operated of High Grade Soft Tissue Sarcoma
Centre Oscar Lambret
NCT04890093 SUSPENDED
Vincristine and Temozolomide in Combination With PEN-866 for Adolescents and Young Adults With Relapsed or Refractory Solid Tumors
National Cancer Institute (NCI)
NCT03652298 TERMINATED
Effects of a Neuroscience-based Technique on Cancer Patients Announced of a Palliative Disease Progression and Partners
Centre Oscar Lambret
NCT01900743 COMPLETED
Phase II Study of Regorafenib in Metastatic Soft Tissue Sarcoma
Centre Oscar Lambret
NCT03602833 COMPLETED
Phase I Study Compound 451238 and Radiotherapy in Soft-tissue Sarcoma
Royal Marsden NHS Foundation Trust
NCT03006848 COMPLETED
A Phase II Trial of Avelumab in Patients With Recurrent or Progressive Osteosarcoma
St. Jude Children's Research Hospital
NCT04794127 COMPLETED
Study on Trabectedin in Combination With Pioglitazone in Patients Myxoid Liposarcomas With Stable Disease After T Alone.
Mario Negri Institute for Pharmacological Research
NCT05000294 SUSPENDED
Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types
University of Florida
NCT03123276 COMPLETED
Pembrolizumab and Gemcitabine Chemotherapy in Leiomyosarcoma and Undifferentiated Pleomorphic Sarcoma
Royal Marsden NHS Foundation Trust
NCT01391962 COMPLETED
Sunitinib or Cediranib for Alveolar Soft Part Sarcoma
National Cancer Institute (NCI)
NCT05846724 WITHDRAWN
Pembrolizumab Plus Lenvatinib in Previously Treated Classic Kaposi Sarcoma
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
NCT04260802 TERMINATED
A Study to Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers
Ocellaris Pharma, Inc.
NCT05481645 TERMINATED
Efficacy and Safety of TQB2450 Injection Combined With Chemotherapy ± Anlotinib Hydrochloride Capsules for Advanced Endometrial Cancer or Sarcoma of Uterus.
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT06562673 COMPLETED
Intra-arterial Cisplatin Plus Rh-endostatin Combined With Systematic Chemotherapy in Osteosarcoma
Shanghai 6th People's Hospital
NCT04067115 COMPLETED
SARC037: A Phase I/II Study to Evaluate the Safety of Trabectedin in Combination With Irinotecan in Ewing Sarcoma Patients
Sarcoma Alliance for Research through Collaboration
NCT03077451 COMPLETED
Nelfinavir Mesylate in Treating Patients With Kaposi Sarcoma
AIDS Malignancy Consortium
NCT03449901 COMPLETED
ADI-PEG 20 in Combination With Gemcitabine and Docetaxel for the Treatment of Soft Tissue Sarcoma, Osteosarcoma, Ewing's Sarcoma, and Small Cell Lung Cancer
Washington University School of Medicine
NCT05235100 COMPLETED
Preoperative IMRT With Concurrent Apatinib for Localised Extremity or Trunk Sarcoma （SPARE-02）
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT05938374 COMPLETED
Preoperative Moderately Fractionated IMRT for Locally Extremity or Trunk Sarcoma (SPARE-03)
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT02406781 COMPLETED
Combination of MK3475 and Metronomic Cyclophosphamide in Patients With Advanced Sarcomas : Multicentre Phase II Trial
Institut Bergonié
NCT03725605 COMPLETED
LTX-315 and Adoptive T-cell Therapy in Advanced Soft Tissue Sarcoma (ATLAS-IT-04)
Lytix Biopharma AS
NCT03526679 COMPLETED
Lenvatinib and Eribulin in Advanced Soft Tissue Sarcoma
National Taiwan University Hospital
NCT04725331 TERMINATED
A Clinical Trial Assessing BT-001 Alone and in Combination With Pembrolizumab in Metastatic or Advanced Solid Tumors
Transgene
NCT05496569 TERMINATED
TQB3616 Capsules in the Treatment of Dedifferentiated Liposarcoma
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT03011528 COMPLETED
First-line Treatment of Ewing Tumours With Primary Extrapulmonary Dissemination in Patients From 2 to 50 Years (CombinaiR3)
Institut Curie
NCT02875548 COMPLETED
A Study to Assess Long-term Safety of Tazemetostat in Adult Participants of All Ages With Any Disease Treated With Tazemetostat in a Previous Clinical Study
Epizyme, Inc.
NCT03425279 COMPLETED
CAB-AXL-ADC Safety and Efficacy Study in Adult and Adolescent Patients With Sarcoma
BioAtla, Inc.
NCT06084689 WITHDRAWN
Targeting MDMD and PD1 in Tumors With Tertiary Lymphoid Structures
Institut Bergonié
NCT04076579 COMPLETED
Trabectedin in Combination With Olaparib in Advanced Unresectable or Metastatic Sarcoma
University of Michigan Rogel Cancer Center
NCT03899805 COMPLETED
A Phase II Study of Eribulin and Pembrolizumab in Soft Tissue Sarcomas
Dana-Farber Cancer Institute
NCT05080790 COMPLETED
Treatment With Dinutuximab Beta, Zoledronic Acid and Low-dose Interleukin (IL-2) in Patients With Leiomyosarcoma
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
NCT05275426 COMPLETED
A Study of LY2880070 and Gemcitabine in People With Ewing Sarcoma,Ewing-Like Sarcoma, and Desmoplastic Small Round Cell Tumor
Memorial Sloan Kettering Cancer Center
NCT01979393 COMPLETED
IRCI Gynae Sarcomas, High Grade Uterine Sarcoma
European Organisation for Research and Treatment of Cancer - EORTC
NCT03862131 TERMINATED
PROactive Evaluation of Function to Avoid CardioToxicity
Washington University School of Medicine
NCT01027910 COMPLETED
PCI-24781 in Combination With Doxorubicin to Treat Sarcoma
Massachusetts General Hospital
NCT04220229 TERMINATED
Cabozantinib With Radiation Therapy for the Treatment of Sarcomas of the Extremities
University of Washington
NCT05563272 TERMINATED
89Zr-girentuximab for PET Imaging of CAIX Positive Solid Tumors
Telix Pharmaceuticals (Innovations) Pty Ltd
NCT02611024 COMPLETED
Pharmacokinetic Study of Lurbinectedin in Combination With Irinotecan in Patients With Selected Solid Tumors
PharmaMar
NCT04530487 TERMINATED
Donor Stem Cell Transplant After Chemotherapy for the Treatment of Recurrent or Refractory High-Risk Solid Tumors in Pediatric and Adolescent-Young Adults
M.D. Anderson Cancer Center
NCT02601950 COMPLETED
A Study of Tazemetostat in Adult Participants With Soft Tissue Sarcoma
Epizyme, Inc.
NCT05580588 TERMINATED
Open-Label Study of the CDK4/6 Inhibitor SPH4336 in Subjects With Locally Advanced or Metastatic Liposarcomas
Shanghai Pharma Biotherapeutics USA Inc.
NCT02815995 COMPLETED
Multi-Arm Study to Test the Efficacy of Immunotherapeutic Agents in Multiple Sarcoma Subtypes
M.D. Anderson Cancer Center
NCT01125449 WITHDRAWN
Study of High Dose Intravenous (IV) Ascorbic Acid in Measurable Solid Tumor Disease
Situs Cancer Research Center
NCT05941325 SUSPENDED
A Single-arm, Open-label, Single-center Prospective Study of Fruquintinib Combined With Envafolimab in the Treatment of Advanced or Unresectable Locally Advanced Bone and Soft Tissue Sarcoma
Shanghai 6th People's Hospital
NCT03951571 COMPLETED
Efficacy and Safety of Anlotinib in Adjuvant Therapy for High-grade Soft Tissue Sarcoma
Fudan University
NCT00742963 COMPLETED
Dose-Escalation Study of TH-302 in Combination With Doxorubicin to Treat Patients With Advanced Soft Tissue Sarcoma
ImmunoGenesis
NCT04579757 TERMINATED
Surufatinib in Combination With Tislelizumab in Subjects With Advanced Solid Tumors
Hutchmed
NCT02632448 COMPLETED
A Study of LY2880070 in Participants With Advanced or Metastatic Cancer
Esperas Pharma Inc.
NCT03660930 TERMINATED
Nab-Sirolimus and Pazopanib Hydrochloride in Treating Patients With Advanced Nonadipocytic Soft Tissue Sarcomas
University of Washington
NCT02799485 COMPLETED
sEphB4-HSA in Treating Patients With Kaposi Sarcoma
AIDS Malignancy Consortium
NCT02658487 COMPLETED
Vosaroxin and Infusional Cytarabine in Treating Patients With Untreated Acute Myeloid Leukemia
Vanderbilt-Ingram Cancer Center
NCT05497843 COMPLETED
Chiauranib for Advanced or Unresectable Soft Tissue Sarcoma(STS)
Chipscreen Biosciences, Ltd.
NCT04383210 TERMINATED
Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors
Elevation Oncology
NCT02584647 TERMINATED
PLX3397 Plus Sirolimus in Unresectable Sarcoma and Malignant Peripheral Nerve Sheath Tumors
Gulam Manji
NCT02100891 TERMINATED
Phase 2 STIR Trial: Haploidentical Transplant and Donor Natural Killer Cells for Solid Tumors
Monica Thakar
NCT00942877 COMPLETED
Phase II Study of Cediranib (AZD2171) in Patients With Alveolar Soft Part Sarcoma
National Cancer Institute (NCI)
NCT03058289 COMPLETED
A Phase 1/2 Safety Study of Intratumorally Dosed INT230-6
Intensity Therapeutics, Inc.
NCT02428192 COMPLETED
Nivolumab Alone or in Combination With Ipilimumab in Treating Patients With Advanced Uterine Leiomyosarcoma
National Cancer Institute (NCI)
NCT06494787 WITHDRAWN
A Phase 2 Study Using Aliya PEF Plus Pembro for Sarcoma
Sarcoma Oncology Research Center, LLC
NCT03190174 COMPLETED
Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers
Sarcoma Oncology Research Center, LLC
NCT02657005 TERMINATED
TK216 in Patients With Relapsed or Refractory Ewing Sarcoma
Oncternal Therapeutics, Inc
NCT02249949 COMPLETED
Efatutazone Dihydrochloride in Treating Patients With Previously Treated Myxoid Liposarcoma That Cannot Be Removed by Surgery
Alliance for Clinical Trials in Oncology
NCT03220035 COMPLETED
Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial)
National Cancer Institute (NCI)
NCT03811886 WITHDRAWN
Natalizumab in Recurrent, Refractory or Progressive Pulmonary Metastatic Osteosarcoma
Case Comprehensive Cancer Center
NCT05302921 COMPLETED
Neoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumors
Children's National Research Institute
NCT04791228 WITHDRAWN
A Pilot Study of Thermodox and MR-HIFU for Treatment of Relapsed Solid Tumors
Children's National Research Institute
NCT03241745 COMPLETED
A Study of Nivolumab in Selected Uterine Cancer Patients
Memorial Sloan Kettering Cancer Center
NCT03997968 COMPLETED
A Phase 1/2 Study of CYT-0851 in B-Cell Malignancies and Advanced Solid Tumors
Cyteir Therapeutics, Inc.
NCT03809637 COMPLETED
A Study of Pemetrexed Plus Cisplatin in Patients With Refractory Soft Tissue Sarcoma
Yonsei University
NCT04996004 TERMINATED
A Study to Learn About the Study Medicine (Called Ontorpacept or TTI-621) Given Alone and in Combination With Doxorubicin in People With Leiomyosarcoma
Pfizer
NCT03233204 COMPLETED
Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial)
National Cancer Institute (NCI)
NCT05017103 TERMINATED
Sintilimab for the Treatment of Locally Advanced, Metastatic, Recurrent, or Unresectable Undifferentiated Pleomorphic Sarcoma, SiARa Cancer Study
M.D. Anderson Cancer Center
NCT03838744 COMPLETED
Randomized Trial in Advanced, Metastatic or Unresectable Soft Tissue Sarcoma After Failure of Standard Treatments.
Italian Sarcoma Group
NCT03250325 COMPLETED
Study of TBI-1301 (NY-ESO-1 T Cell Receptor Gene Transduced Autologous T Lymphocytes) in Patients with Synovial Sarcoma
Takara Bio Inc.
NCT06217536 WITHDRAWN
Neoadjuvant Lurbinectedin and Preoperative Radiation for Treating Soft Tissue Sarcomas
University of California, San Francisco
NCT04183062 WITHDRAWN
BIO-11006 for Osteosarcoma and Ewing's Sarcoma Lung Metastases
Nicklaus Children's Hospital f/k/a Miami Children's Hospital
NCT03116529 TERMINATED
Neoadjuvant Durvalumab and Tremelimumab Plus Radiation for High Risk Soft-Tissue Sarcoma
University of Maryland, Baltimore
NCT04887298 COMPLETED
Study of Liposomal Annamycin for the Treatment of Subjects with Soft-Tissue Sarcomas (STS) with Pulmonary Metastases
Moleculin Biotech, Inc.
NCT03345485 COMPLETED
Study of the Safety, Pharmacokinetics and Efficacy of Tinostamustine in Patients With Advanced Solid Tumors.
Mundipharma Research Limited
NCT05301764 COMPLETED
A Study of LVGN6051 Combined With Anlotinib in Patient With Soft Tissue Sarcoma
Lyvgen Biopharma Holdings Limited
NCT05854966 WITHDRAWN
CPI-613 Given With Metformin in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML)
Wake Forest University Health Sciences
NCT00819169 TERMINATED
QUILT-3.026: AMG 655 in Combination With AMG 479 in Advanced, Refractory Solid Tumors
NantCell, Inc.
NCT03277924 COMPLETED
Trial of Sunitinib and/or Nivolumab Plus Chemotherapy in Advanced Soft Tissue and Bone Sarcomas
Grupo Espanol de Investigacion en Sarcomas
NCT03338959 COMPLETED
Pembrolizumab and Radiation Therapy in Treating Patients With Intermediate or High-Grade Soft Tissue Sarcoma
Fred Hutchinson Cancer Center
NCT04154189 COMPLETED
A Study to Compare the Efficacy and Safety of Ifosfamide and Etoposide With or Without Lenvatinib in Children, Adolescents and Young Adults With Relapsed and Refractory Osteosarcoma
Eisai Inc.
NCT02978859 COMPLETED
Sitravatinib in Advanced Liposarcoma and Other Soft Tissue Sarcomas
Columbia University
NCT03320330 COMPLETED
Pepinemab in Treating Younger Patients With Recurrent, Relapsed, or Refractory Solid Tumors
Children's Oncology Group
NCT02636725 COMPLETED
Axitinib and Pembrolizumab in Subjects With Advanced Alveolar Soft Part Sarcoma and Other Soft Tissue Sarcomas
Jonathan Trent, MD, PhD
NCT03508726 COMPLETED
High Dose Ascorbate With Preoperative Radiation in Patients With Locally Advanced Soft Tissue Sarcomas
Mohammed Milhem
NCT02029430 COMPLETED
A Study to Investigate ALDOXORUBICIN in HIV-infected Subjects With Kaposi's Sarcoma
ImmunityBio, Inc.
NCT05093322 COMPLETED
A Study of Surufatinib in Combination With Gemcitabine in Pediatric, Adolescent, and Young Adult Patients With Recurrent or Refractory Solid Tumors
Hutchmed
NCT02235701 COMPLETED
Study to Investigate the Safety and Activity of Aldoxorubicin Plus Ifosfamide/Mesna in Subjects With Metastatic Soft Tissue Sarcoma
ImmunityBio, Inc.
NCT01514188 COMPLETED
Preliminary Efficacy and Safety of INNO-206 Compared to Doxorubicin in Advanced Soft Tissue Sarcoma
ImmunityBio, Inc.
NCT03926936 COMPLETED
FUlvestrant in Gynecological Cancers That Are Potentially Hormone Sensitive: the FUCHSia Study
Frederic Amant
NCT03132155 TERMINATED
QUILT-3.031: AMG 337 in Subjects With Advanced or Metastatic Clear Cell Sarcoma
NantPharma, LLC
NCT01459484 COMPLETED
ABCB1/P-glycoprotein Expression as Biologic Stratification Factor for Patients With Non Metastatic Osteosarcoma
Italian Sarcoma Group
NCT02624388 TERMINATED
Study of Genistein in Pediatric Oncology Patients (UVA-Gen001)
University of Virginia
NCT04742959 COMPLETED
Study of TT-00420 (Tinengotinib) Tablet as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumors
TransThera Sciences (Nanjing), Inc.
NCT02340884 COMPLETED
A Pilot RCT of the PRISM Intervention for AYAs With Cancer
Seattle Children's Hospital
NCT03711279 TERMINATED
A Study of SHR-1210 Plus Apatinib in Patients With Soft Tissue Sarcoma
Jiangsu HengRui Medicine Co., Ltd.
NCT03012620 COMPLETED
Secured Access to Pembrolizumab for Patients With Selected Rare Cancer Types
UNICANCER
NCT05262101 TERMINATED
Clinical Trial of TQB2858 Injection in the Treatment of Advanced High-grade Sarcoma
Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.
NCT02470091 COMPLETED
Denosumab in Treating Patients With Recurrent or Refractory Osteosarcoma
Children's Oncology Group
NCT05154630 TERMINATED
Study on Tolerability and Pharmacokinetics of TQB2858 Injection in Subjects With Advanced Malignant Tumors
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT03422679 TERMINATED
Study of CB-103 in Adult Patients With Advanced or Metastatic Solid Tumours and Haematological Malignancies
Cellestia Biotech AG
NCT01336803 COMPLETED
Differentiation of Bone Sarcomas and Osteomyelitis With Ferumoxytol-Enhanced MRI
Heike E Daldrup-Link
NCT04118166 COMPLETED
Ipilimumab + Nivolumab + Cryotherapy in Metastatic or Locally Advanced Soft Tissue Sarcoma
Kristen Ganjoo
NCT01524926 COMPLETED
CREATE: Cross-tumoral Phase 2 With Crizotinib
European Organisation for Research and Treatment of Cancer - EORTC
NCT05116683 TERMINATED
ATX-101 in Advanced Dedifferentiated Liposarcoma and Leiomyosarcoma
Benjamin Izar
NCT03458728 TERMINATED
Safety, Tolerability, Efficacy and Pharmacokinetics of Copanlisib in Pediatric Patients
Bayer
NCT03056001 COMPLETED
Safety, Tolerability, and Efficacy of Doxorubicin and Pembrolizumab for Sarcoma
Wake Forest University Health Sciences
NCT05558280 SUSPENDED
Qarziba for Patients in Relapsed/Refractory High-grade Osteosarcoma
Prof. Franca Fagioli
NCT02048371 COMPLETED
SARC024: A Blanket Protocol to Study Oral Regorafenib in Patients With Selected Sarcoma Subtypes
Sarcoma Alliance for Research through Collaboration
NCT02584309 COMPLETED
Doxorubicin With Upfront Dexrazoxane for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma
Washington University School of Medicine
NCT02484443 COMPLETED
Dinutuximab in Combination With Sargramostim in Treating Patients With Recurrent Osteosarcoma
National Cancer Institute (NCI)
NCT03063632 COMPLETED
Testing the Combination of Two Experimental Drugs MK-3475 (Pembrolizumab) and Interferon-gamma for the Treatment of Mycosis Fungoides and Sézary Syndrome and Advanced Synovial Sarcoma
National Cancer Institute (NCI)
NCT02500797 COMPLETED
Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Sarcoma That Cannot Be Removed by Surgery
National Cancer Institute (NCI)
NCT02304458 COMPLETED
Nivolumab With or Without Ipilimumab in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Sarcomas
National Cancer Institute (NCI)
NCT03860207 TERMINATED
Study of the Safety and Efficacy of Humanized 3F8 Bispecific Antibody (Hu3F8-BsAb) in Patients With Relapsed/Refractory Neuroblastoma, Osteosarcoma and Other Solid Tumor Cancers
Y-mAbs Therapeutics
NCT04145700 TERMINATED
CAMPFIRE: A Study of Ramucirumab (LY3009806) in Children and Young Adults With Synovial Sarcoma
Eli Lilly and Company
NCT04644315 TERMINATED
A Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid Tumors
Hoffmann-La Roche
NCT00667342 COMPLETED
A Study of Bevacizumab in Combination With Chemotherapy for Treatment of Osteosarcoma
St. Jude Children's Research Hospital
NCT01112384 COMPLETED
A Study of SB939 in Patients With Translocation-Associated Recurrent/Metastatic Sarcomas
NCIC Clinical Trials Group
NCT02988817 COMPLETED
Enapotamab Vedotin (HuMax-AXL-ADC) Safety Study in Patients With Solid Tumors
Genmab
NCT01719744 COMPLETED
Study of ENMD-2076 in Patients With Advanced/Metastatic Soft Tissue Sarcoma
University Health Network, Toronto
NCT00788125 TERMINATED
Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors
City of Hope Medical Center
NCT02432274 COMPLETED
Study of Lenvatinib in Children and Adolescents With Refractory or Relapsed Solid Malignancies and Young Adults With Osteosarcoma
Eisai Limited
NCT03317457 COMPLETED
Durvalumab and Tremelimumab Compared to Doxorubicin in Patients With Advanced or Metastatic Soft Tissue Sarcoma
AIO-Studien-gGmbH
NCT03798106 COMPLETED
A Study of Pazopanib and Durvalumab for Metastatic Soft Tissue Sarcoma
Yonsei University
NCT05582031 WITHDRAWN
Regorafenib With Tislelizumab in Patients With Selected Mismatch Repair-Proficient/Microsatellite Stable Cancers
Translational Research in Oncology
NCT04593758 COMPLETED
To Evaluate Maximally Tolerated Dose (MTD), Safety and Efficacy of CPI-613® (Devimistat) Plus Hydroxychloroquine in Patients With Relapsed or Refractory Clear Cell Sarcoma of Soft Tissue
Cornerstone Pharmaceuticals
NCT04190433 WITHDRAWN
Autophagy Activation for the Alleviation of Cardiomyopathy Symptoms After Anthracycline Treatment, ATACAR Trial
Mayo Clinic
NCT04730349 TERMINATED
A Study of Bempegaldesleukin (BEMPEG: NKTR-214) in Combination With Nivolumab in Children, Adolescents and Young Adults With Recurrent or Treatment-resistant Cancer
Bristol-Myers Squibb
NCT03435640 TERMINATED
REVEAL Study of NKTR-262 in Combination With NKTR-214 and Nivolumab in Patients With Locally Advanced / Metastatic Solid Tumor Malignancies
Nektar Therapeutics
NCT02511132 COMPLETED
A Two-part Phase IIb Trial of Vigil (Bi-shRNAfurin and GMCSF Augmented Autologous Tumor Cell Immunotherapy) in Ewing's Sarcoma
Gradalis, Inc.
NCT05302570 WITHDRAWN
Neoadjuvant Short-course Hypofractionated PBT for Non-metastatic RPS
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT02643303 COMPLETED
A Study of Tremelimumab and IV Durvalumab Plus Poly-ICLC in Subjects With Biopsy-accessible Cancers
Ludwig Institute for Cancer Research
NCT03590210 COMPLETED
Combined Treatment With Nivolumab and Trabectedin in Patients With Metastatic or Inoperable Soft Tissue Sarcomas
University Medicine Greifswald
NCT01495598 COMPLETED
Pomalidomide for Kaposi Sarcoma in People With or Without HIV
National Cancer Institute (NCI)
NCT03441360 COMPLETED
Study to Assess Safety and Preliminary Activity of Eribulin Mesylate in Pediatric Participants With Relapsed/Refractory Rhabdomyosarcoma (RMS), Non-rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS) and Ewing Sarcoma (EWS)
Eisai Inc.
NCT03524898 TERMINATED
NAPAGE: NAb-PAclitaxel and GEmcitabine in Advanced Soft Tissue Sarcoma
Swiss Cancer Institute
NCT01879085 COMPLETED
Study of Vorinostat in Combination With Gemcitabine and Docetaxel in Advanced Sarcoma
Melissa Burgess, MD
NCT02307500 COMPLETED
Regorafenib in Patients With Metastatic Solid Tumors Who Have Progressed After Standard Therapy
Istituto Clinico Humanitas
NCT02601209 TERMINATED
Sapanisertib or Pazopanib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Sarcoma
National Cancer Institute (NCI)
NCT01462630 COMPLETED
Pazopanib Hydrochloride in Treating Patients With Advanced Angiosarcoma
Fox Chase Cancer Center
NCT03245450 COMPLETED
Study Evaluating the Safety and Efficacy of Eribulin Mesilate in Combination With Irinotecan Hydrochloride in Children With Refractory or Recurrent Solid Tumors
Eisai Inc.
NCT03810976 COMPLETED
A Study of Eribulin With Gemcitabine in Patients With Advanced Liposarcoma or Leiomyosarcoma
Yonsei University
NCT03275818 COMPLETED
Trial of Nab-paclitaxel in Patients With Desmoid Tumors and Multiply Relapsed/Refractory Desmoplastic Small Round Cell Tumors and Ewing Sarcoma
Grupo Espanol de Investigacion en Sarcomas
NCT02357810 COMPLETED
Pazopanib Hydrochloride and Topotecan Hydrochloride in Treating Patients With Metastatic Soft Tissue and Bone Sarcomas
Northwestern University
NCT03365791 COMPLETED
PDR001 Plus LAG525 for Patients With Advanced Solid and Hematologic Malignancies
Novartis Pharmaceuticals
NCT02659020 COMPLETED
A Study of Olaratumab (LY3012207) in Participants With Advanced Soft Tissue Sarcoma
Eli Lilly and Company
NCT03074318 TERMINATED
Avelumab and Trabectedin in Treating Patients With Liposarcoma or Leiomyosarcoma That is Metastatic or Cannot Be Removed by Surgery
Fred Hutchinson Cancer Center
NCT02048722 COMPLETED
Daily Oral Regorafenib for Chemotherapy-Refractory, Metastatic and Locally Advanced Angiosarcoma
Northwestern University
NCT02821507 COMPLETED
Sirolimus and Cyclophosphamide in Metastatic or Unresectable Myxoid Liposarcoma and Chondrosarcoma
Leiden University Medical Center
NCT03641326 TERMINATED
Sunitinib in Sarcomas of the Central Nervous System
National Cancer Institute (NCI)
NCT02050919 COMPLETED
Sorafenib Tosylate, Combination Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With High-Risk Stage IIB-IV Soft Tissue Sarcoma
OHSU Knight Cancer Institute
NCT05042934 WITHDRAWN
Lurbinectedin With or Without Irinotecan in Treating Patients With Relapsed or High Risk Metastatic Ewing Sarcoma
M.D. Anderson Cancer Center
NCT01057121 COMPLETED
Lenalidomide in Treating Patients With AIDS-Associated Kaposi's Sarcoma
National Cancer Institute (NCI)
NCT03296553 COMPLETED
Impact of Valganciclovir on Severe IRIS-Kaposi Sarcoma Mortality: an Open-label, Parallel, Randomized Controlled-trial.
National Institute of Cancerología
NCT02054104 TERMINATED
Adjuvant Tumor Lysate Vaccine and Iscomatrix With or Without Metronomic Oral Cyclophosphamide and Celecoxib in Patients With Malignancies Involving Lungs, Esophagus, Pleura, or Mediastinum
National Cancer Institute (NCI)
NCT02487979 COMPLETED
Glembatumumab Vedotin in Treating Patients With Recurrent or Refractory Osteosarcoma
National Cancer Institute (NCI)
NCT02452554 COMPLETED
Lorvotuzumab Mertansine in Treating Younger Patients With Relapsed or Refractory Wilms Tumor, Rhabdomyosarcoma, Neuroblastoma, Pleuropulmonary Blastoma, Malignant Peripheral Nerve Sheath Tumor, or Synovial Sarcoma
Children's Oncology Group
NCT02247544 COMPLETED
Efficacy Study on Trabectedin in Retroperitoneal Leiomyosarcoma and Well Differentiated/Dedifferentiated Liposarcoma
Italian Sarcoma Group
NCT01222767 COMPLETED
Study of Zalypsis® (PM00104) in Patients With Unresectable Locally Advanced and/or Metastatic Ewing Family of Tumors (EFT) Progressing After at Least One Prior Line of Chemotherapy
PharmaMar
NCT01532687 COMPLETED
Gemcitabine With or Without Pazopanib in Treating Patients With Refractory Soft Tissue Sarcoma
OHSU Knight Cancer Institute
NCT02808247 TERMINATED
Ph II Nintedanib vs. Ifosfamide in Soft Tissue Sarcoma
European Organisation for Research and Treatment of Cancer - EORTC
NCT01913652 COMPLETED
Ph II Cabazitaxel DD Liposarcoma
European Organisation for Research and Treatment of Cancer - EORTC
NCT02732015 TERMINATED
Rolapitant Hydrochloride in Preventing Nausea/Vomiting in Patients With Sarcoma Receiving Chemotherapy
M.D. Anderson Cancer Center
NCT04906876 WITHDRAWN
A Phase 2 Study of 9-ING-41Combined With Chemotherapy in Adolescents and Adults With Advanced Sarcomas
Brown University
NCT02181829 COMPLETED
Whole Lung IMRT in Children and Adults With Synovial Sarcoma and Lung Metastases
Memorial Sloan Kettering Cancer Center
NCT02888665 COMPLETED
Pembrolizumab and Doxorubicin Hydrochloride in Treating Patients With Sarcoma That is Metastatic or Cannot Be Removed by Surgery
Fred Hutchinson Cancer Center
NCT04464967 WITHDRAWN
Safety and Preliminary Efficacy of SNK01 in Combination With Trastuzumab or Cetuximab in Subjects With Advanced HER2 or EGFR Cancers
NKGen Biotech, Inc.
NCT02581384 TERMINATED
Stereotactic Body Radiotherapy (SBRT) for Pulmonary Metastases in Ewing Sarcoma, Rhabdomyosarcoma, and Wilms Tumors
Dana-Farber Cancer Institute
NCT01759303 TERMINATED
Study of Pazopanib in the Treatment of Osteosarcoma Metastatic to the Lung
Emerald Clinical Inc.
NCT02116777 COMPLETED
Talazoparib and Temozolomide in Treating Younger Patients With Refractory or Recurrent Malignancies
National Cancer Institute (NCI)
NCT01140737 COMPLETED
A Study of Axitinib in Patients With Advanced Angiosarcoma and Other Soft Tissue Sarcomas
Sheffield Teaching Hospitals NHS Foundation Trust
NCT01276236 COMPLETED
Effects of Maraviroc (MVC) on HIV-related Kaposi's Sarcoma (KS)
University of California, San Francisco
NCT02448537 COMPLETED
A Phase II Multi-Strata Study of PM01183 as a Single Agent or in Combination With Conventional Chemotherapy in Metastatic and/or Unresectable Sarcomas
Massachusetts General Hospital
NCT01833520 COMPLETED
Phase I Dose Escalation of Monthly Intravenous Ra-223 Dichloride in Osteosarcoma
M.D. Anderson Cancer Center
NCT01543802 TERMINATED
Study of Preoperative Therapy With Pazopanib (Votrient®) to Treat High-risk Soft Tissue Sarcoma
Heidelberg University
NCT01876043 TERMINATED
Efficacy and Safety of Plitidepsin in Patients With Advanced Unresectable or Metastatic, Relapsed/Refractory, Dedifferentiated Liposarcoma (DLPS): an Exploratory Phase II Multicenter Trial
Institut Bergonié
NCT02423863 COMPLETED
In Situ, Autologous Therapeutic Vaccination Against Solid Cancers With Intratumoral Hiltonol®
Oncovir, Inc.
NCT03013127 TERMINATED
A Study of Pembrolizumab in Patients With Relapsed Or Metastatic Osteosarcoma Not Eligible for Curative Surgery
Oslo University Hospital
NCT02301039 COMPLETED
SARC028: A Phase II Study of the Anti-PD1 Antibody Pembrolizumab (MK-3475) in Patients With Advanced Sarcomas
Sarcoma Alliance for Research through Collaboration
NCT01987102 COMPLETED
Investigation of [6R] 5,10-methylenetetrahydrofolate (Arfolitixorin) as Rescue Therapy for Osteosarcoma Patients Treated With HDMTX.
Isofol Medical AB
NCT00880542 TERMINATED
Sorafenib and Ifosfamide in Treating Patients With High-Grade Soft Tissue Sarcoma or Bone Sarcoma That Can Be Removed by Surgery
Jonsson Comprehensive Cancer Center
NCT02300545 COMPLETED
Pazopanib as Front-Line Therapy in Patients With Non-Resectable or Metastatic Soft Tissue Sarcomas Who Are Not Candidates for Chemotherapy
Washington University School of Medicine
NCT01692496 COMPLETED
Activity and Tolerability of Pazopanib in Advanced and/or Metastatic Liposarcoma. A Phase II Clinical Trial
Grupo Espanol de Investigacion en Sarcomas
NCT03698227 TERMINATED
OlaReDo - Olaratumab and Rechallenge With Doxorubicin in Soft Tissue Sarcoma Patients
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
NCT02609984 TERMINATED
Study to Compare the Safety and Efficacy of CMB305 With Atezolizumab to Atezolizumab Alone in Participants With Sarcoma (IMDZ-C232/V943A-002)
Immune Design, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
NCT01975519 COMPLETED
A Phase 1B Dose-escalation and Phase 2a Study of Carotuximab (TRC105) in Combination With Pazopanib in Patients With Advanced Soft Tissue Sarcoma
Tracon Pharmaceuticals Inc.
NCT03104335 WITHDRAWN
Apatinib for Advanced Soft Tissue Sarcoma Patients: a Phase 2, Multicenter Trial
Peking University People's Hospital
NCT02097238 COMPLETED
Eribulin Mesylate in Treating Patients With Recurrent or Refractory Osteosarcoma
National Cancer Institute (NCI)
NCT01154816 COMPLETED
Alisertib in Treating Young Patients With Recurrent or Refractory Solid Tumors or Leukemia
Children's Oncology Group
NCT01593748 COMPLETED
A Phase II Trial Comparing Gemcitabine and Pazopanib Versus Gemcitabine and Docetaxel for Patients With Advanced Soft Tissue Sarcoma
Medical University of South Carolina
NCT01848457 COMPLETED
Preventing Nephrotoxicity and Ototoxicity From Osteosarcoma Therapy
Children's Hospital of Philadelphia
NCT02496520 COMPLETED
Dendritic Cell-based Immunotherapy for Advanced Solid Tumours of Children and Young Adults
Clinica Universidad de Navarra, Universidad de Navarra
NCT01392352 TERMINATED
HYPAZ: Hypertension Induced by Pazopanib
Cambridge University Hospitals NHS Foundation Trust
NCT01442662 COMPLETED
Efficacy of Gemcitabine With Pazopanib as Second Line Treatment in Patient With Metastatic or Relapsed Uterine
UNICANCER
NCT03913806 COMPLETED
FLuoresence Image Guided Surgery With A VEGF-targeted Tracer in Soft-tissue Sarcomas in Humans Approach With Bevacizumab-IRDye 800CW
University Medical Center Groningen
NCT01065441 COMPLETED
Experimental Therapeutic Cancer Vaccine Created In-situ in Patients With Stage II-Stage IV Cancer
Michael Har-Noy
NCT00752206 TERMINATED
A Placebo-Controlled Study of Saracatinib (AZD0530) in Patients With Recurrent Osteosarcoma Localized to the Lung
Sarcoma Alliance for Research through Collaboration
NCT01277744 COMPLETED
Pilot Study of Hyperthermic Peritoneal Perfusion (HIPEC) for Adolescent and Young Adults With Desmoplastic Small Round Cell Tumor
M.D. Anderson Cancer Center
NCT01005043 COMPLETED
Therapy Trial to Determine the Safety and Efficacy of Heavy Ion Radiotherapy in Patients With Osteosarcoma
University Hospital Heidelberg
NCT01962103 COMPLETED
Study to Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid Tumors
Celgene
NCT03121833 COMPLETED
Endostar Combined With Chemotherapy for Stage Ⅳ Soft Tissue Sarcoma
Tianjin Medical University Cancer Institute and Hospital
NCT01561495 TERMINATED
Proton Radiotherapy for Extremity Soft Tissue Sarcoma
Abramson Cancer Center at Penn Medicine
NCT00717522 TERMINATED
Efficacy and Safety Study of CC-4047 (Pomalidomide) to Treat Advanced Soft Tissue Sarcoma
Celgene
NCT01886105 TERMINATED
Combination of External Beam Radiotherapy With 153Sm-EDTMP to Treat High Risk Osteosarcoma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT01492673 COMPLETED
Cyclophosphamide, Topotecan, and Bevacizumab (CTB) in Patients With Relapsed/Refractory Ewing's Sarcoma and Neuroblastoma
Memorial Sloan Kettering Cancer Center
NCT00643565 COMPLETED
A Study of Avastin (Bevacizumab) in Combination With Standard Chemotherapy in Children and Adolescents With Sarcoma.
Hoffmann-La Roche
NCT02062632 TERMINATED
Doxepin Hydrochloride in Treating Esophageal Pain in Patients With Thoracic Cancer Receiving Radiation Therapy to the Thorax With or Without Chemotherapy
Mayo Clinic
NCT02441309 TERMINATED
A Eurosarc Study of Mifamurtide in Advanced Osteosarcoma (MEMOS)
University of Oxford
NCT02849366 COMPLETED
Combination of Cryosurgery and NK Immunotherapy for Recurrent Sarcoma
Fuda Cancer Hospital, Guangzhou
NCT03397186 WITHDRAWN
Immune Changes Following Trabectedin in Patients With Metastatic or Unresectable Sarcoma
Fred Hutchinson Cancer Center
NCT01782313 COMPLETED
A Phase II Study of Tivozanib in Patients With Metastatic and Non-resectable Soft Tissue Sarcomas
Northwestern University
NCT02689336 WITHDRAWN
Erlotinib in Combination With Temozolomide in Treating Relapsed/Recurrent/Refractory Pediatric Solid Tumors
Washington University School of Medicine
NCT01574716 COMPLETED
Sarcoma Study of MORAb-004 Utilization: Research and Clinical Evaluation
Morphotek
NCT01168232 COMPLETED
Ixabepilone in Treating Patients With Recurrent or Persistent Uterine Cancer
National Cancer Institute (NCI)
NCT01247571 COMPLETED
Pazopanib Hydrochloride in Treating Patients With Recurrent or Persistent Uterine Cancer
National Cancer Institute (NCI)
NCT01220609 COMPLETED
Ixabepilone in Treating Patients With Recurrent or Persistent Leiomyosarcoma of the Uterus Previously Treated With Chemotherapy
National Cancer Institute (NCI)
NCT01650090 COMPLETED
Phase 2 Study of Inhaled Lipid Cisplatin in Pulmonary Recurrent Osteosarcoma
Eleison Pharmaceuticals LLC.
NCT01637961 COMPLETED
Alisertib in Treating Patients With Recurrent or Persistent Leiomyosarcoma of the Uterus
National Cancer Institute (NCI)
NCT02575066 TERMINATED
Clinical Study of Concurrent Pazopanib and Radiotherapy for Non-metastatic Sarcoma Patients
The Netherlands Cancer Institute
NCT00589121 COMPLETED
Image-Guided Radiation Therapy in Treating Patients With Primary Soft Tissue Sarcoma of the Shoulder, Arm, Hip, or Leg
Radiation Therapy Oncology Group
NCT00978471 COMPLETED
Adjuvant High-Dose Thiotepa and Stem Cell Rescue Associated With Conventional Chemotherapy in Relapsed Osteosarcoma
Centre Leon Berard
NCT02008877 COMPLETED
SARC023: Ganetespib and Sirolimus in Patients With MPNST (Malignant Peripheral Nerve Sheath Tumors)
Sarcoma Alliance for Research through Collaboration
NCT02718482 TERMINATED
Phase II Trial for the Treatment of Relapsed Osteosarcoma
Italian Sarcoma Group
NCT00767819 COMPLETED
Treatment of Patients With RAD001 With Progressive Sarcoma
Novartis Pharmaceuticals
NCT00949325 COMPLETED
Safety and Efficacy Study of Torisel and Liposomal Doxorubicin for Patients With Recurrent Sarcoma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT01661283 COMPLETED
SARC016: Study of Everolimus With Bevacizumab to Treat Refractory Malignant Peripheral Nerve Sheath Tumors
Sarcoma Alliance for Research through Collaboration
NCT01752569 TERMINATED
A Study of Selumetinib in Patients With Kaposi's Sarcoma
Sheffield Teaching Hospitals NHS Foundation Trust
NCT02303262 COMPLETED
SARC018: A Study of Mocetinostat and Gemcitabine in Patients With Metastatic Leiomyosarcoma
Sarcoma Alliance for Research through Collaboration
NCT02255110 TERMINATED
A Japanese Trial of TH-302 in Subjects With Locally Advanced Unresectable or Metastatic Soft Tissue Sarcoma
Merck KGaA, Darmstadt, Germany
NCT01614795 COMPLETED
Cixutumumab and Temsirolimus in Treating Younger Patients With Recurrent or Refractory Sarcoma
National Cancer Institute (NCI)
NCT00918489 COMPLETED
Study on Efficacy and Tolerability of Vorinostat in Patients With Advanced, Metastatic Soft Tissue Sarcoma (STS)
Heidelberg University
NCT01986829 TERMINATED
Cryoablation, Radiofrequency Ablation, or Microwave Ablation in Treating Patients With Metastatic Sarcoma Stable on Chemotherapy
Washington University School of Medicine
NCT00070109 COMPLETED
Trabectedin in Treating Young Patients With Recurrent or Refractory Soft Tissue Sarcoma or Ewing's Family of Tumors
Children's Oncology Group
NCT00484341 COMPLETED
Phase II Study of NGR-hTNF in Combination With Doxorubicin in Patients Affected by Soft Tissue Sarcomas.
AGC Biologics S.p.A.
NCT00617890 TERMINATED
A Study to Determine the Activity of Robatumumab (SCH 717454) in Participants With Relapsed Osteosarcoma or Ewing's Sarcoma (MK-7454-002/P04720)
Merck Sharp & Dohme LLC
NCT01154452 COMPLETED
Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma
National Cancer Institute (NCI)
NCT02011126 WITHDRAWN
Imetelstat Sodium in Treating Younger Patients With Relapsed or Refractory Solid Tumors
Children's Oncology Group
NCT01696669 COMPLETED
Study of Intensive Chemotherapy, Surgery and Radiotherapy to Treat Ewing's Sarcoma in Children and Young Adults
Grupo Espanol de Investigacion en Sarcomas
NCT00923936 COMPLETED
Pilot Study of Liposomal Doxorubicin Combined With Bevacizumab Followed by Bevacizumab Monotherapy in Adults With Advanced Kaposi s Sarcoma
National Cancer Institute (NCI)
NCT00668148 COMPLETED
A Five-Tier, Open-Label Study of IMC-A12 in Advanced Sarcoma
Eli Lilly and Company
NCT01553539 COMPLETED
Therapeutic Angiotensin-(1-7) in Treating Patients With Metastatic Sarcoma That Cannot Be Removed By Surgery
Wake Forest University Health Sciences
NCT02331251 TERMINATED
Study of Pembrolizumab Plus Chemotherapy in Patients With Advanced Cancer (PembroPlus)
Western Regional Medical Center
NCT00659360 COMPLETED
AZD0530 in Treating Patients With Recurrent Locally Advanced or Metastatic Soft Tissue Sarcoma
National Cancer Institute (NCI)
NCT00686842 TERMINATED
PTC299 in Treating Patients With HIV-Related Kaposi Sarcoma
AIDS Malignancy Consortium
NCT01764802 COMPLETED
Psychosexual Intervention in Patients With Stage I-III Gynecologic or Breast Cancer
Ohio State University Comprehensive Cancer Center
NCT01055028 TERMINATED
Paclitaxel + Bevacizumab (Avastin) for the Treatment of Metastatic or Unresectable Angiosarcoma
Stanford University
NCT01610570 TERMINATED
Mithramycin for Children and Adults With Solid Tumors or Ewing Sarcoma
National Cancer Institute (NCI)
NCT01210222 COMPLETED
Trebananib in Treating Patients With Persistent or Recurrent Endometrial Cancer
Gynecologic Oncology Group
NCT01984892 TERMINATED
Treatment of Solid Tumors With Intratumoral Hiltonol® (Poly-ICLC)
Nina Bhardwaj
NCT01418001 TERMINATED
Gemcitabine and Docetaxel in Combination With Pazopanib (Gem/Doce/Pzb) for the Neoadjuvant Treatment of Soft Tissue Sarcoma (STS)
Memorial Sloan Kettering Cancer Center
NCT02267083 COMPLETED
Efficacy and Safety Study of GPX-150 to Treat Soft Tissue Sarcoma
Gem Pharmaceuticals
NCT02229981 WITHDRAWN
Early Phase Evaluation of ABC294640 in Patients With Refractory/Relapsed Diffuse Large B-cell Lymphoma or Kaposi Sarcoma
RedHill Biopharma Limited
NCT02249702 COMPLETED
Activity of Trabectedin or Gemcitabine + Docetaxel in Uterine Leiomyosarcoma
Mario Negri Institute for Pharmacological Research
NCT01653028 COMPLETED
Alisertib in Treating Patients With Advanced or Metastatic Sarcoma
National Cancer Institute (NCI)
NCT01313884 TERMINATED
Cyclophosphamide, Doxorubicin, Vincristine w/ Irinotecan and Temozolomide in Ewings Sarcoma
Stanford University
NCT01169350 TERMINATED
18F-Fluoromisonidazole and Fludeoxyglucose F 18 PET/CT Patients With Soft Tissue Sarcoma
National Cancer Institute (NCI)
NCT02113826 TERMINATED
Pazopanib for Metastatic Alveolar Soft Part Sarcoma
Seoul National University Hospital
NCT01209598 COMPLETED
PD0332991 (Palbociclib) in Patients With Advanced or Metastatic Liposarcoma
Memorial Sloan Kettering Cancer Center
NCT01055314 COMPLETED
Temozolomide, Cixutumumab, and Combination Chemotherapy in Treating Patients With Metastatic Rhabdomyosarcoma
National Cancer Institute (NCI)
NCT01861951 COMPLETED
A Trial Comparing Two Medications as First Treatment in Elderly Patients With Metastatic or Advanced Soft Tissue Sarcoma
Hannover Medical School
NCT02259348 TERMINATED
Repeat Transplantation for Relapsed or Refractory Hematologic Malignancies Following Prior Transplantation
St. Jude Children's Research Hospital
NCT01583543 COMPLETED
Olaparib in Adults With Recurrent/Metastatic Ewing's Sarcoma
Massachusetts General Hospital
NCT01288573 COMPLETED
A Combined Study in Pediatric Cancer Patients for Dose Ranging and Efficacy/Safety of Plerixafor Plus Standard Regimens for Mobilization Versus Standard Regimens Alone
Genzyme, a Sanofi Company
NCT01222715 COMPLETED
Vinorelbine Tartrate and Cyclophosphamide in Combination With Bevacizumab or Temsirolimus in Treating Patients With Recurrent or Refractory Rhabdomyosarcoma
National Cancer Institute (NCI)
NCT00856050 COMPLETED
Letrozole in Women With Advanced Estrogen/Progesterone Receptor Positive Uterine Leiomyosarcoma
Dana-Farber Cancer Institute
NCT01259375 COMPLETED
Amrubicin Chemotherapy as First Line in Metastatic or Unresectable Soft Tissue Sarcoma
University of Utah
NCT01141491 COMPLETED
Trivalent Ganglioside Vaccine With Immunological Adjuvant or Immunological Adjuvant Alone in Metastatic Sarcoma Patients Who Are Rendered Disease Free
MabVax Therapeutics, Inc.
NCT01716689 COMPLETED
Clinical Study of Metronomic Oral Cyclophosphamide in Patients With Advanced Sarcomas
National Cancer Centre, Singapore
NCT01621477 TERMINATED
T-Cell Replete Haploidentical Donor Hematopoietic Stem Cell Plus Natural Killer (NK) Cell Transplantation in Patients With Hematologic Malignancies Relapsed or Refractory Despite Previous Allogeneic Transplant
St. Jude Children's Research Hospital
NCT01506596 COMPLETED
Study of Pazopanib in the Treatment of Surgically Unresectable or Metastatic Liposarcoma
Vector Oncology
NCT00815945 COMPLETED
Multicenter Trial With PegLiposomal Doxorubicin and Carboplatin Combination Chemotherapy in Gynecological Sarcomas and Mixed Epithelial-Mesenchymal Tumors
AGO Study Group
NCT00802880 COMPLETED
Dacarbazine for Metastatic Soft Tissue and Bone Sarcoma
Washington University School of Medicine
NCT02131480 COMPLETED
Study of Doxorubicin and Trabectedin in First Line Treatment on Patients With Metastatic Leiomyosarcoma
Gustave Roussy, Cancer Campus, Grand Paris
NCT01061606 TERMINATED
Temsirolimus in Treating Patients With Recurrent or Persistent Cancer of the Uterus
National Cancer Institute (NCI)
NCT02367651 WITHDRAWN
Study of Pazopanib Versus Placebo as Maintenance Therapy for Advanced Soft Tissue Sarcoma
GlaxoSmithKline
NCT02201420 COMPLETED
Evaluation of Tc 99m Tilmanocept Localization in Primary Cutaneous Kaposi's Sarcoma and Lymphatic Drainage by SPECT/CT
Navidea Biopharmaceuticals
NCT01067690 COMPLETED
Treatment With Indinavir and Chemotherapy for Advanced Classical Kaposi's Sarcoma
Barbara Ensoli, MD, PhD
NCT01283035 COMPLETED
A Phase II Study of Akt Inhibitor MK2206 in the Treatment of Recurrent Platinum-Resistant Ovarian, Fallopian Tube, or Peritoneal Cancer
National Cancer Institute (NCI)
NCT01719302 COMPLETED
Docetaxel, Gemcitabine and Pazopanib as Treatment for Soft Tissue Sarcoma
University of Vermont
NCT01347034 COMPLETED
Radiation Therapy and Intratumoral Autologous Dendritic Cells in Soft Tissue Sarcomas (STS)
H. Lee Moffitt Cancer Center and Research Institute
NCT01458249 COMPLETED
An Open-label, Multicenter, Phase 2 Study to Evaluate the Efficacy and Safety of Eribulin Mesylate in Previously Treated Subjects With Advanced or Metastatic Soft Tissue Sarcoma (Study E7389-J081-217)
Eisai Co., Ltd.
NCT00887809 COMPLETED
Gemcitabine and Docetaxel With Bevacizumab in Selected Sarcoma Subtypes
Memorial Sloan Kettering Cancer Center
NCT00837148 COMPLETED
Sorafenib and Dacarbazine in Soft Tissue Sarcoma
Memorial Sloan Kettering Cancer Center
NCT01842594 TERMINATED
A Phase II Trial of Combined Hydroxychloroquine and Sirolimus in Soft Tissue Sarcoma
Shin Kong Wu Ho-Su Memorial Hospital
NCT01684449 COMPLETED
Gemcitabine Plus Rapamycin Versus Gemcitabine to Treat Advanced Soft Tissue Sarcoma
Grupo Espanol de Investigacion en Sarcomas
NCT01104298 TERMINATED
Doxorubicin vs. Trabectedin Plus Doxorubicin in Non Operable and/or Metastatic STS
Grupo Espanol de Investigacion en Sarcomas
NCT01623869 COMPLETED
Trebananib in Treating Patients With Advanced Angiosarcoma That Cannot Be Removed by Surgery
National Cancer Institute (NCI)
NCT00633789 COMPLETED
Phase II Study of Brivanib (BMS-582664) to Treat Multiple Tumor Types
Bristol-Myers Squibb
NCT01206140 COMPLETED
Selumetinib With or Without Temsirolimus in Treating Patients With Metastatic, Recurrent, or Locally Advanced Soft Tissue Sarcoma That Cannot Be Removed By Surgery
National Cancer Institute (NCI)
NCT00743509 COMPLETED
A Phase II Study of Oral Cyclophosphamide and Sirolimus (OCR) in Advanced Sarcoma
University of Michigan Rogel Cancer Center
NCT01016015 COMPLETED
Temsirolimus and Cixutumumab in Treating Patients With Locally Advanced, Metastatic, or Recurrent Soft Tissue Sarcoma or Bone Sarcoma
National Cancer Institute (NCI)
NCT01296815 COMPLETED
Intralesional Bevacizumab for Treating AIDS-associated Kaposi´s Sarcoma of the Larynx, Pharynx and Oral Cavity
Centro de Investigación en. Enfermedades Infecciosas, Mexico
NCT02137564 WITHDRAWN
Gamma Secretase Inhibitor PF-03084014 in Treating Patients With AIDS-Associated Kaposi Sarcoma
AIDS Malignancy Consortium
NCT01804374 COMPLETED
Phase II Open Label, Non-randomized Study of Sorafenib and Everolimus in Relapsed and Non-resectable Osteosarcoma
Italian Sarcoma Group
NCT01174537 WITHDRAWN
New Castle Disease Virus (NDV) in Glioblastoma Multiforme (GBM), Sarcoma and Neuroblastoma
Hadassah Medical Organization
NCT00755261 TERMINATED
Phase II Study of Doxorubicin and Avastin® in Sarcoma.
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT01010672 COMPLETED
Phase II Study of Ridaforolimus (MK-8669) With Metastatic Bone or Soft-tissue Sarcoma Patients (MK-8669-030 AM1)
Merck Sharp & Dohme LLC
NCT02429973 COMPLETED
Trial With Gemcitabine and Rapamycin in Second Line of Metastatic Osteosarcoma
Broto, Javier Martín, M.D.
NCT00969917 WITHDRAWN
Study Evaluating the Efficacy and Safety of IPI 504 in Patients With Advanced Dedifferentiated Liposarcoma
Infinity Pharmaceuticals, Inc.
NCT00831844 COMPLETED
Cixutumumab in Treating Patients With Relapsed or Refractory Solid Tumors
National Cancer Institute (NCI)
NCT01281865 COMPLETED
Everolimus in Combination With Imatinib Mesylate in Treating Patients With Locally Advanced, Locally Recurrent, or Metastatic Soft Tissue Sarcoma
National Cancer Institute (NCI)
NCT00634322 TERMINATED
High Dose Methotrexate With Leucovorin Rescue With or Without Glucarpidase in Osteosarcoma
BTG International Inc.
NCT00516295 COMPLETED
Vincristine Sulfate, Topotecan Hydrochloride, and Cyclophosphamide With or Without Bevacizumab in Treating Young Patients With Refractory or First Recurrent Extracranial Ewing Sarcoma
National Cancer Institute (NCI)
NCT00740597 TERMINATED
Intensity-Modulated Radiation Therapy in Treating Patients Undergoing Surgery for Stage IB, Stage II, or Stage III Soft Tissue Sarcoma
City of Hope Medical Center
NCT00918281 COMPLETED
Reproducibility of 18F Uptake by Solid Tumors Using PET Imaging Following Intravenous Administration of (18F) Injection
GE Healthcare
NCT00937495 COMPLETED
Vorinostat and Bortezomib in Treating Patients With Advanced Soft Tissue Sarcoma
National Cancer Institute (NCI)
NCT00521092 WITHDRAWN
Sunitinib Malate in Treating East African Patients With Kaposi Sarcoma
National Cancer Institute (NCI)
NCT01048723 TERMINATED
Study of RAD001 in Soft Tissue Extremity and/or Retroperitoneal Sarcomas
H. Lee Moffitt Cancer Center and Research Institute
NCT01079832 COMPLETED
Stereotactic Radiosurgery Using CyberKnife in Treating Women With Advanced or Recurrent Gynecological Malignancies
Case Comprehensive Cancer Center
NCT01095926 COMPLETED
Pharmacokinetic Study of Doxorubicin in Children With Cancer
University Hospital Muenster
NCT00864032 COMPLETED
Trial of Neoadjuvant Conformal Radiotherapy Plus Sorafenib for Patients With Soft Tissue Sarcoma of the Extremity and Body Wall
University of California, Davis
NCT01136499 COMPLETED
Efficacy and Safety Assessment of Oral LBH589 in Adult Patients With Advanced Soft TIssue Sarcoma After Pre-treatment Failure
Centre Leon Berard
NCT01102608 COMPLETED
Neoadyuvant High-dose of Ifosfamide and Concurrent Radiotherapy in Soft Tissue Sarcoma
Grupo Espanol de Investigacion en Sarcomas
NCT01412515 TERMINATED
A Phase II Study With Tumor Molecular Pharmacodynamic (MPD) Evaluation of Oral mTOR-inhibitor Everolimus (RAD001) 10 mg Daily in Patients Suffering From Classic or Endemic Kaposi's Sarcoma
Institut National de la Santé Et de la Recherche Médicale, France
NCT05711615 RECRUITING
Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma
National Cancer Institute (NCI)
NCT02298959 ACTIVE NOT RECRUITING
Testing the PD-1 Antibody, MK3475, Given With Ziv-aflibercept in Patients With Advanced Cancer
National Cancer Institute (NCI)
NCT07297667 NOT YET RECRUITING
GCAR1, a Chimeric Antigen Receptor (CAR) T-CELL Therapy for Relapsed/Refractory GPNMB-Expressing Solid Tumours
Canadian Cancer Trials Group
NCT05492682 RECRUITING
START: Safety and Anti-Tumor Activity of PeptiCRAd-1 in Treatment of Cancer
Valo Therapeutics Oy
NCT04337177 ACTIVE NOT RECRUITING
Flavored, Oral Irinotecan VAL-413 (Orotecan®) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumors
Valent Technologies, LLC
NCT07578506 NOT YET RECRUITING
A Study of Ta-NPs Plus Radiotherapy for Locally Recurrent Retroperitoneal Sarcoma
West China Hospital
NCT07297979 RECRUITING
Evaluation of Xaluritamig in Adults, Adolescents and Children With Relapsed or Refractory Ewing Sarcoma (EWS)
Amgen
NCT06500819 RECRUITING
Autologous B7-H3 Chimeric Antigen Receptor T Cells in Relapsed/Refractory Solid Tumors
Stanford University
NCT07052383 RECRUITING
Safety and Efficacy of DIT309 in Advanced Bone and Soft Tissue Sarcomas
Tcelltech Inc.
NCT05621668 RECRUITING
A First-In-Human Phase 1 Trial of T-Cell Membrane-Anchored Tumor Targeted Il12 (Attil12)- T-Cell Therapy in Subjects With Advanced/Metastatic Soft Tissue and Bone Sarcoma
M.D. Anderson Cancer Center
NCT06414434 ACTIVE NOT RECRUITING
BTX-A51 in Patients With Liposarcoma or CIC-rearranged Sarcoma
Michael Wagner, MD
NCT02659930 ACTIVE NOT RECRUITING
Pomalidomide in Combination With Liposomal Doxorubicin in People With Advanced or Refractory Kaposi Sarcoma
National Cancer Institute (NCI)
NCT03054792 ENROLLING BY INVITATION
Molecular-Functional Imaging of Hypoxia in Childhood Sarcomas
The Hospital for Sick Children
NCT06021626 RECRUITING
A Study of CRD3874-SI in People With Solid Tumors
Memorial Sloan Kettering Cancer Center
NCT07261631 RECRUITING
Phase I Study of [177Lu]Lu-DFC413 in Patients With Solid Tumors
Novartis Pharmaceuticals
NCT04902443 RECRUITING
Pomalidomide and Nivolumab in People With Virus-Associated Malignancies With or Without HIV
National Cancer Institute (NCI)
NCT05264974 RECRUITING
Novel RNA-lipid Particle (RNA-LP) Vaccine for Anti-PD-1 Antibody Therapy Sensitization
University of Florida
NCT04483778 ACTIVE NOT RECRUITING
B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults
Seattle Children's Hospital
NCT06926283 RECRUITING
A Study of DXC008 in Patients With Prostate Cancer and Other Solid Tumors
Hangzhou DAC Biotechnology Co., Ltd.
NCT02390752 RECRUITING
Phase I Trial of TURALIO(R) (Pexidartinib, PLX3397) in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN) and Tenosynovial Giant Cell Tumor ...
National Cancer Institute (NCI)
NCT01953900 ACTIVE NOT RECRUITING
iC9-GD2-CAR-VZV-CTLs/Refractory or Metastatic GD2-positive Sarcoma and Neuroblastoma
Baylor College of Medicine
NCT01590069 ACTIVE NOT RECRUITING
Aerosolized Aldesleukin in Treating Patients With Lung Metastases
M.D. Anderson Cancer Center
NCT06066138 RECRUITING
A Study of Therapeutic Drug Monitoring-Based Atezolizumab Dosing
National Cancer Institute (NCI)
NCT05813327 ACTIVE NOT RECRUITING
Neoadjuvant ADI-PEG 20 + Ifosfamide + Radiotherapy in Soft Tissue Sarcoma
Washington University School of Medicine
NCT01746238 ACTIVE NOT RECRUITING
Bevacizumab/Doxorubicin/Radiation for Sarcoma
Massachusetts General Hospital
NCT06083883 RECRUITING
Phase I/Ib Study of NK Expressing an Affinity-enhanced T-cell Receptor (TCR) Against the NY-ESO-1
M.D. Anderson Cancer Center
NCT04897321 RECRUITING
B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)
St. Jude Children's Research Hospital
NCT04308330 RECRUITING
Vorinostat in Combination With Chemotherapy in Relapsed/Refractory Solid Tumors and CNS Malignancies
New York Medical College
NCT03361436 ACTIVE NOT RECRUITING
Eribulin and Radiation Therapy in Treating Patients With Retroperitoneal Liposarcoma That Can Be Removed by Surgery
OHSU Knight Cancer Institute
NCT06566092 ACTIVE NOT RECRUITING
Study of Autologous Tumor-Infiltrating Lymphocytes in Pediatric, Adolescent, and Young Adult Participants
Iovance Biotherapeutics, Inc.
NCT04715191 RECRUITING
Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors
Baylor College of Medicine
NCT05646082 ACTIVE NOT RECRUITING
Preliminary Assessment of Safety and Tolerability of Dostarlimab in Combination Antiretroviral Therapy (cART) Refractory HIV Associated Kaposi Sarcoma
Imperial College London
NCT06025747 RECRUITING
Evaluation of Abemaciclib and Radiation Therapy Before Surgery for the Treatment of High-Risk Adipocytic Retroperitoneal Sarcoma
University of Washington
NCT03721068 RECRUITING
Study of CAR T-Cells Targeting the GD2 With IL-15+iCaspase9 for Relapsed/Refractory Neuroblastoma or Relapsed/Refractory Osteosarcoma
UNC Lineberger Comprehensive Cancer Center
NCT04514484 ACTIVE NOT RECRUITING
Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV
National Cancer Institute (NCI)
NCT03478462 ACTIVE NOT RECRUITING
Dose Escalation Study of CLR 131 in Pediatric Relapsed/Refractory Malignant Tumors Including Neuroblastoma and Sarcomas
Cellectar Biosciences, Inc.
NCT03715933 RECRUITING
Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas
Inhibrx Biosciences, Inc
NCT07194044 RECRUITING
Metastatic Ewing's Trial Testing Schedule Enhancement to Improve Outcomes
H. Lee Moffitt Cancer Center and Research Institute
NCT05735184 RECRUITING
A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML
Kura Oncology, Inc.
NCT04420975 ACTIVE NOT RECRUITING
Nivolumab and BO-112 Before Surgery for the Treatment of Resectable Soft Tissue Sarcoma
Jonsson Comprehensive Cancer Center
NCT05103631 ACTIVE NOT RECRUITING
Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in Autologous T Cells for Solid Tumors
Baylor College of Medicine
NCT07297160 NOT YET RECRUITING
CD70.CAR for CD70+ Lymphoma, Myeloma and Solid Tumors
Baylor College of Medicine
NCT06492954 RECRUITING
Atezolizumab in Combination With Stereotactic Body Radiation Therapy (SBRT) and Surgery for Relapsed Osteosarcoma
Emory University
NCT07144254 RECRUITING
Tegavivint With Gemcitabine in Patients With Relapsed or Refractory Osteosarcoma
Emory University
NCT06474676 RECRUITING
T Cell Membrane-Anchored Tumor-Targeted IL12 -Modified TIL Cell Therapy (attIL12-TIL) for Advanced/Metastatic Soft Tissue and Bone Sarcoma Patients.
M.D. Anderson Cancer Center
NCT06308419 RECRUITING
A Phase I Trial of Combination Gemcitabine and Nab-Sirolimus in Advanced Leiomyosarcomas or Advanced Soft-Tissue Sarcomas With TSC2 or TSC1 Loss-of-function Mutations or Deletions
M.D. Anderson Cancer Center
NCT07197554 RECRUITING
A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies
SEED Therapeutics, Inc.
NCT07148050 RECRUITING
Immunotherapy for Solid Tumor Malignancies in Pediatrics Using Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor T Cells
Seattle Children's Hospital
NCT07227571 RECRUITING
Genetically Engineered Cells (FH-FOLR1 ST CAR T Cells) for the Treatment of Advanced Refractory or Recurrent/Progressive Osteosarcoma, FIERCe Trial
Fred Hutchinson Cancer Center
NCT07222735 RECRUITING
Hypofractionated Radiation in Combination With B7-H3-CAR T Cells for Pediatric Patients With Relapsed/Refractory Sarcomas
St. Jude Children's Research Hospital
NCT07211737 NOT YET RECRUITING
NKG2D.Zeta-NK Cell Conditioning With C7R.GD2.CAR-T Cells for Patients With Relapsed or Refractory Osteosarcoma or Neuroblastoma
Baylor College of Medicine
NCT03628209 ACTIVE NOT RECRUITING
Nivolumab or Nivolumab and Azacitidine in Patients With Recurrent, Resectable Osteosarcoma
H. Lee Moffitt Cancer Center and Research Institute
NCT04969835 RECRUITING
A Study Evaluating the Safety, Pharmacokinetics and Early Efficacy of AVA6000 in Solid Tumours
Avacta Life Sciences Ltd
NCT05352750 ACTIVE NOT RECRUITING
Phase 1 Study of SON-1010 in Adult Patients With Advanced Solid Tumors
Sonnet BioTherapeutics
NCT03900793 RECRUITING
Losartan + Sunitinib in Treatment of Osteosarcoma
University of Colorado, Denver
NCT02432963 ACTIVE NOT RECRUITING
Vaccine Therapy and Pembrolizumab in Treating Patients With Solid Tumors That Have Failed Prior Therapy
City of Hope Medical Center
NCT07172958 RECRUITING
Selective Antigen Specific T Cells and CAR T Cells in Subjects With Relapsed/Refractory Embryonal Tumors (SABRE)
Children's National Research Institute
NCT00902044 ACTIVE NOT RECRUITING
Her2 Chimeric Antigen Receptor Expressing T Cells in Advanced Sarcoma
Baylor College of Medicine
NCT05827614 ACTIVE NOT RECRUITING
Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR Inhibitor BBI-825, in Subjects With Tumors With Oncogene Amplifications
Boundless Bio, Inc.
NCT04995003 RECRUITING
HER2 Chimeric Antigen Receptor (CAR) T Cells in Combination With Checkpoint Blockade in Patients With Advanced Sarcoma
Baylor College of Medicine
NCT04377932 ACTIVE NOT RECRUITING
Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors
Baylor College of Medicine
NCT06968988 RECRUITING
Zanzalintinib in Combination With Ipilimumab and Nivolumab in Patients With Metastatic Soft Tissue Sarcoma
Washington University School of Medicine
NCT04616248 ACTIVE NOT RECRUITING
In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors
University of Southern California
NCT05830084 ACTIVE NOT RECRUITING
Phase Ib / Regorafenib With Conventional Chemotherapy/Newly Diagnosed Patients/ Multimetastatic Ewing Sarcoma
Gustave Roussy, Cancer Campus, Grand Paris
NCT05075993 ACTIVE NOT RECRUITING
Study of LVGN3616 and LVGN6051±LVGN7409 in Combination With Nab-Paclitaxel or Bevacizumab and Cyclophosphamide in Metastatic Solid Tumors
M.D. Anderson Cancer Center
NCT05400603 RECRUITING
Allogeneic Expanded Gamma Delta T Cells With GD2 Chemoimmunotherapy in Relapsed /Refractory Neuroblastoma or Refractory/ Relapsed Osteosarcoma
Emory University
NCT05859074 RECRUITING
A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer
Memorial Sloan Kettering Cancer Center
NCT02869217 ACTIVE NOT RECRUITING
Study of TBI-1301 (NY-ESO-1 Specific TCR Gene Transduced Autologous T Lymphocytes) in Patients With Solid Tumors
University Health Network, Toronto
NCT07027423 NOT YET RECRUITING
BOLD-100 Plus Doxorubicin in Advanced Soft Tissue Sarcomas
University Health Network, Toronto
NCT02811523 RECRUITING
In Vivo Lung Perfusion for Pulmonary Metastases of Sarcoma
University Health Network, Toronto
NCT05238883 ACTIVE NOT RECRUITING
A Study of HFB200301 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors
HiFiBiO Therapeutics
NCT03618381 ACTIVE NOT RECRUITING
EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults
Seattle Children's Hospital
NCT05312411 ACTIVE NOT RECRUITING
A Phase I Feasibility And Safety Study of Fluorescein-Specific (FITC-E2) CAR T Cells In Combination With Parenterally Administered Folate-Fluorescein (UB-TT170) For Osteogenic Sarcoma
Seattle Children's Hospital
NCT06156410 RECRUITING
Cabozantinib With Ifosfamide in Relapsed/Refractory Sarcomas
Children's Hospital of Philadelphia
NCT07224568 NOT YET RECRUITING
Cytokine Armored GPC3 Specific Chimeric Antigen Receptor Expressing T-cells in Adults With Solid Tumors
Seattle Children's Hospital
NCT06198296 RECRUITING
Immunotherapy For Adults With GPC3-Positive Solid Tumors Using IL-15 and IL-21 Armored GPC3-CAR T Cells
Baylor College of Medicine
NCT06957431 RECRUITING
Zanzalintinib Combined With Eribulin in Advanced Liposarcoma and Leiomyosarcoma
Washington University School of Medicine
NCT04185883 ACTIVE NOT RECRUITING
Sotorasib Activity in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation (CodeBreak 101)
Amgen
NCT02508038 RECRUITING
Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors
University of Wisconsin, Madison
NCT06812052 RECRUITING
Short Course Radiation Treatment for Patients With Primary or Locally Recurrent Retroperitoneal Sarcoma Prior to Surgery
Brigham and Women's Hospital
NCT05227326 RECRUITING
AOH1996 for the Treatment of Refractory Solid Tumors
City of Hope Medical Center
NCT06789172 RECRUITING
A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors
Epkin
NCT06942143 RECRUITING
An Open-label, Phase I Clinical Trial of Super1 TCR-T in NY-ESO-1-positive Patients With Advanced Solid Tumors
Guangzhou FineImmune Biotechnology Co., LTD.
NCT06508307 RECRUITING
A Phase I Clinical Study of Intratumoral Injection Oncolytic Vaccinia Virus GC001 in Patient With Advanced Solid Tumors
GONGCHU Biotechnology Co., Ltd
NCT07118176 RECRUITING
Determining the Biodistribution of an Imaging Tracer (68Ga-FAPi-46) in Patients With Solid Tumors or Hematologic Cancers
Jonsson Comprehensive Cancer Center
NCT05821231 ACTIVE NOT RECRUITING
Study Evaluating the Safety and Efficacy of MEDI5752 in Combination With Stereotactic Radiotherapy in Patients With Metastatic Sarcoma
Institut Claudius Regaud
NCT03635632 ACTIVE NOT RECRUITING
C7R-GD2.CART Cells for Patients With Relapsed or Refractory Neuroblastoma and Other GD2 Positive Cancers (GAIL-N)
Baylor College of Medicine
NCT06644755 RECRUITING
First-in-Human Trial of DS-2243a in Participants With Advanced Solid Tumors
Daiichi Sankyo
NCT05857969 RECRUITING
Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling
Florida International University
NCT05999396 RECRUITING
FIH, Bispecific CD276xCD3 Antibody CC-3 in Patients With Colorectal Cancer
German Cancer Research Center
NCT06889766 RECRUITING
NY-ESO-1-redirected T Cells in Patients With Advanced Melanoma and Sarcoma
Centre Hospitalier Universitaire Vaudois
NCT06839703 NOT YET RECRUITING
International Phase I Trial of Dinutuximab Beta With VDC/IE in GD2-Positive Ewing Sarkoma
Prof. Dr. Dirk Reinhardt
NCT06748872 NOT YET RECRUITING
EPITOME-1015-I: a Study to Investigate the Safety and Tolerability of MDG1015 in Patients with Epithelial Ovarian Cancer, Gastroesophageal Adenocarcinoma, Round Cell Liposarcoma And/or Synovial Sarcoma
Medigene AG
NCT06537596 RECRUITING
89Zr-olaratumab Dosimetry in Participants With Soft Tissue Sarcoma
Telix Pharmaceuticals (Innovations) Pty Ltd
NCT06699576 NOT YET RECRUITING
ARTEMIS-103: Phase 1b Study of HS-20093 Combinations in Patients with Bone and Soft Tissue Sarcoma.
Hansoh BioMedical R&D Company
NCT04511871 ACTIVE NOT RECRUITING
A Phase I Trial of CCT303-406 in Patients With Relapsed or Refractory HER2 Positive Solid Tumors
Shanghai PerHum Therapeutics Co., Ltd.
NCT05130255 RECRUITING
GD2-SADA:177Lu-DOTA Complex in Patients With Solid Tumors Known to Express GD2
Y-mAbs Therapeutics
NCT06235125 RECRUITING
Safety and Feasibility of Intraoperative Visualization With Cytalux in Children
Ann & Robert H Lurie Children's Hospital of Chicago
NCT06412458 NOT YET RECRUITING
IM83 Clinical Study of CAR-T Cell Therapy in Patients With Relapsed or Refractory Osteosarcoma
Beijing Immunochina Medical Science & Technology Co., Ltd.
NCT06087341 RECRUITING
A Phase I Trial of Memory T Cells Expressing an NKG2D Chimeric Antigen Receptor in Children, Adolescents and Young Adults With Advanced Sarcoma
Antonio Pérez Martínez
NCT06340204 RECRUITING
Weekly Irinotecan Liposomes in Recurrent or Refractory Ewing Sarcoma
Peking University People's Hospital
NCT04282044 RECRUITING
Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies
BioEclipse Therapeutics
NCT04595994 RECRUITING
Selinexor Plus Gemcitabine in Selected Advanced Soft-tissue Sarcoma and Osteosarcoma
Grupo Espanol de Investigacion en Sarcomas
NCT05361954 NOT YET RECRUITING
Study to Assess the Safety and Preliminary Efficacy of STI-1386 Oncolytic Virus in Relapsed or Refractory Solid Tumors
Sorrento Therapeutics, Inc.
NCT04539366 SUSPENDED
Testing a New Immune Cell Therapy, GD2-Targeted Modified T-cells (GD2CART), in Children, Adolescents, and Young Adults With Relapsed/Refractory Osteosarcoma and Neuroblastoma, The GD2-CAR PERSIST Trial
National Cancer Institute (NCI)
NCT04619056 COMPLETED
First-in-man Clinical Trial of CEB-01 PLGA Membrane in Recurrent or Locally Advanced Retroperitoneal Soft Tissue Sarcoma
CEBIOTEX
NCT01875601 COMPLETED
NK White Blood Cells and Interleukin in Children and Young Adults With Advanced Solid Tumors
National Cancer Institute (NCI)
NCT01552434 TERMINATED
Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease
M.D. Anderson Cancer Center
NCT04833582 COMPLETED
A Study of Azenosertib (ZN-c3) in Combination With Gemcitabine in Subjects With Osteosarcoma
K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc
NCT02787642 COMPLETED
A Study of Olaparib With Concomitant Radiotherapy in Locally Advanced/Unresectable Soft-tissue Sarcoma
Institut Bergonié
NCT04052334 COMPLETED
Lymphodepletion Plus Adoptive Cell Therapy With High Dose IL-2 in Adolescent and Young Adult Patients With Soft Tissue Sarcoma
H. Lee Moffitt Cancer Center and Research Institute
NCT01625351 COMPLETED
A Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and Lymphomas
St. Jude Children's Research Hospital
NCT04037527 TERMINATED
Gemcitabine and Docetaxel With Radiation in Adults With Soft Tissue Sarcoma of the Extremities
Wake Forest University Health Sciences
NCT05116254 TERMINATED
Sarcomas and DDR-Inhibition; a Combined Modality Study
The Netherlands Cancer Institute
NCT04751383 COMPLETED
Testing the Combination of Two Immunotherapy Drugs (Magrolimab and Dinutuximab) in Patients With Relapsed or Refractory Neuroblastoma or Relapsed Osteosarcoma
National Cancer Institute (NCI)
NCT02408861 TERMINATED
Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classical Hodgkin Lymphoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery
National Cancer Institute (NCI)
NCT04204941 TERMINATED
Tazemetostat in Combination With Doxorubicin as Frontline Therapy for Advanced Epithelioid Sarcoma
Epizyme, Inc.
NCT01858168 COMPLETED
Phase I Study of Olaparib and Temozolomide for Ewings Sarcoma or Rhabdoomyosarcoma
Massachusetts General Hospital
NCT06438783 TERMINATED
TQB2928 Injection Combined Anlotinib Hydrochloride Capsule in Recurrent/Metastatic Osteosarcoma and Other Solid Tumors
Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.
NCT02936102 TERMINATED
A Study of FAZ053 Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies.
Novartis Pharmaceuticals
NCT05229601 TERMINATED
A Study of HFB301001 in Adult Patients With Advanced Solid Tumors
HiFiBiO Therapeutics
NCT03514407 TERMINATED
A Study of INCB059872 in Relapsed or Refractory Ewing Sarcoma
Incyte Corporation
NCT03217266 COMPLETED
Navtemadlin and Radiation Therapy in Treating Patients With Soft Tissue Sarcoma
National Cancer Institute (NCI)
NCT03085225 COMPLETED
Trabectedin Combined With Durvalumab in Patients With Advanced Pretreated Soft-tissue Sarcomas and Ovarian Carcinomas.
Institut Bergonié
NCT04242238 COMPLETED
Study of DCC-3014 in Combination With Avelumab in Patients With Advanced or Metastatic Sarcomas
Memorial Sloan Kettering Cancer Center
NCT06670976 WITHDRAWN
Propranolol Plus Standard Radiation Therapy Before Surgery for the Treatment of Patients With Soft Tissue Sarcoma
Roswell Park Cancer Institute
NCT05605522 TERMINATED
A Study of [225Ac]-FPI-2059 in Adult Participants With Solid Tumours
3B Pharmaceuticals GmbH
NCT02784795 TERMINATED
A Study of LY3039478 in Participants With Advanced or Metastatic Solid Tumors
Eli Lilly and Company
NCT05858710 COMPLETED
Study of DPPG2-TSL-DOX Combined With Hyperthermia in Soft Tissue Sarcoma
Thermosome GmbH
NCT06299163 TERMINATED
NM32-2668 in Adult Patients With Selected Advanced Solid Tumors
Numab Therapeutics AG
NCT05432193 TERMINATED
FAPi Radioligand OpeN-Label, Phase 1 Study to Evaluate Safety, Tolerability and DosImetry of [Lu-177]-PNT6555; A Dose Escalation Study for TReatment of Patients With Select Solid Tumors (FRONTIER)
POINT Biopharma, a wholly owned subsidiary of Eli Lilly and Company
NCT02517918 COMPLETED
Metronomic Chemotherapy in Patients With Advanced Solid Tumor With Bone Metastasis and Advanced Pretreated Osteosarcoma
Institut Bergonié
NCT04811196 COMPLETED
A Study of Different Dosing Schedules of Selinexor in Sarcoma Patients
University Health Network, Toronto
NCT04553692 TERMINATED
Phase 1a/1b Study of Aplitabart (IGM-8444) Alone or in Combination in Participants with Relapsed, Refractory, or Newly Diagnosed Cancers
IGM Biosciences, Inc.
NCT05166577 TERMINATED
Nanatinostat Plus Valganciclovir in Advanced EBV+ Solid Tumors and in Combination With Pembrolizumab in EBV+ RM-NPC
Viracta Therapeutics, Inc.
NCT03157167 COMPLETED
An Evaluation of Tc 99m Tilmanocept by Intravenous (IV) and Subcutaneous (SC) Injection in Kaposi Sarcoma (KS)
Navidea Biopharmaceuticals
NCT04965753 TERMINATED
FHD-609 in Subjects With Advanced Synovial Sarcoma or Advanced SMARCB1-Loss Tumors
Foghorn Therapeutics Inc.
NCT04537715 COMPLETED
Effects of Itraconazole and Rifampin on the Blood Tazemetostat Levels
Epizyme, Inc.
NCT01638533 COMPLETED
Romidepsin in Treating Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Solid Tumors With Liver Dysfunction
National Cancer Institute (NCI)
NCT05100628 TERMINATED
A Study of NOX66 Plus Doxorubicin in Anthracycline-naïve, Adult Patients With Soft Tissue Sarcoma
Noxopharm Limited
NCT02076906 COMPLETED
MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid Tumors
AeRang Kim
NCT05355753 TERMINATED
A Study to Assess the Safety and Tolerability of CFT8634 in Locally Advanced or Metastatic SMARCB1-Perturbed Cancers, Including Synovial Sarcoma and SMARCB1-Null Tumors
C4 Therapeutics, Inc.
NCT03960060 TERMINATED
A Study of CCT301-59 CAR T Therapy in Adult Subjects With Recurrent or Refractory Solid Tumors
Shanghai PerHum Therapeutics Co., Ltd.
NCT04521946 WITHDRAWN
Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer
M.D. Anderson Cancer Center
NCT03126591 COMPLETED
A Study of Olaratumab (LY3012207) Plus Pembrolizumab in Participants With Advanced or Metastatic Soft Tissue Sarcoma
Eli Lilly and Company
NCT03990597 WITHDRAWN
StrataXRT in Preventing Radiation Dermatitis in Pediatric Patients Undergoing Radiation Therapy to the Brain or Spinal Cord
M.D. Anderson Cancer Center
NCT02601937 COMPLETED
EZH2 Inhibitor Tazemetostat in Pediatric Subjects With Relapsed or Refractory INI1-Negative Tumors or Synovial Sarcoma
Epizyme, Inc.
NCT02484391 COMPLETED
CPI-613, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Granulocytic Sarcoma
Wake Forest University Health Sciences
NCT03604783 TERMINATED
Phase 1, First-in-human Study of Oral TP-1287 in Patients with Advanced Solid Tumors
Sumitomo Pharma America, Inc.
NCT06252727 WITHDRAWN
Fluorescent Aided Resection and Evaluation of Soft Tissue Sarcomas (FLARES)
University of California, Davis
NCT02595866 COMPLETED
Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer
National Cancer Institute (NCI)
NCT03752398 COMPLETED
A Study of XmAb®23104 in Subjects With Selected Advanced Solid Tumors (DUET-3)
Xencor, Inc.
NCT01803152 COMPLETED
Dendritic Cell Vaccine for Children and Adults With Sarcoma
Macarena De La Fuente, MD
NCT05578820 COMPLETED
Safety, Tolerability and Pharmacokinetics Investigation of Stimotimagene Copolymerplasmid
Gene Surgery LLC
NCT05538572 COMPLETED
A Study of PRT3645 in Participants With Select Advanced or Metastatic Solid Tumors
Prelude Therapeutics
NCT04893018 TERMINATED
NT-I7 for Kaposi Sarcoma in Patients With or Without HIV
Fred Hutchinson Cancer Center
NCT05420727 COMPLETED
Theranostics in Soft Tissue Sarcoma Using a Vascular Disruption Approach
John O. Prior
NCT02107963 COMPLETED
A Phase I Trial of T Cells Expressing an Anti-GD2 Chimeric Antigen Receptor in Children and Young Adults With GD2+ Solid Tumors
National Cancer Institute (NCI)
NCT03670069 TERMINATED
Itacitinib in Treating Patients With Refractory Metastatic/Advanced Sarcomas
Fred Hutchinson Cancer Center
NCT05061537 TERMINATED
Study of PF-07263689 in Participants With Selected Advanced Solid Tumors
Pfizer
NCT03727789 TERMINATED
CBL0137 in Treating Patients With Advanced Extremity Melanoma or Sarcoma
Roswell Park Cancer Institute
NCT03761095 COMPLETED
A Study of Unesbulin (PTC596) in Combination With Dacarbazine in Participants With Advanced Leiomyosarcoma (LMS)
PTC Therapeutics
NCT04900766 TERMINATED
A Study of Mitoxantrone Hydrochloride Liposome Injection in Subjects With Advanced Bone and Soft Tissue Sarcoma
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
NCT04176016 TERMINATED
Phase I Study of Radiolabeled OTSA101-DTPA in Patients With Relapsed or Refractory Synovial Sarcoma
OncoTherapy Science, Inc.
NCT01661400 COMPLETED
Anti-Angiogenic Therapy Post Transplant (ASCR) for Pediatric Solid Tumors
Washington University School of Medicine
NCT01896505 COMPLETED
A Phase I Trial to Assess the Effects of Food and Formulation on PK of KPT-330 in Patients With Sarcoma
Karyopharm Therapeutics Inc
NCT03454451 COMPLETED
CPI-006 Alone and in Combination With Ciforadenant and With Pembrolizumab for Patients With Advanced Cancers
Corvus Pharmaceuticals, Inc.
NCT05159518 COMPLETED
A Study of PRT2527 in Participants With Advanced Solid Tumors
Prelude Therapeutics
NCT02498665 COMPLETED
A Study of DSP-7888 Dosing Emulsion in Adult Patients With Advanced Malignancies
Sumitomo Pharma America, Inc.
NCT02736565 COMPLETED
Pbi-shRNA™ EWS/FLI1 Type 1 LPX in Subjects With Advanced Ewing's Sarcoma
Gradalis, Inc.
NCT05905341 WITHDRAWN
Study of PF-07224826, as a Single Agent or in Combination With Endocrine Therapy in Participants With Breast Cancer and Other Advanced Solid Tumors.
Pfizer
NCT03240861 TERMINATED
Genetically Engineered PBMC and PBSC Expressing NY-ESO-1 TCR After a Myeloablative Conditioning Regimen to Treat Patients With Advanced Cancer
Jonsson Comprehensive Cancer Center
NCT02644460 COMPLETED
Abemaciclib in Children With DIPG or Recurrent/Refractory Solid Tumors
Emory University
NCT03450122 COMPLETED
Modified T Cells, Chemotherapy, and Aldesleukin With or Without LV305 and CMB305 in Treating Participants With Advanced or Recurrent Sarcoma
M.D. Anderson Cancer Center
NCT02897375 COMPLETED
Palbociclib With Cisplatin or Carboplatin in Advanced Solid Tumors
Emory University
NCT02536183 TERMINATED
A Phase I Study of Lyso-thermosensitive Liposomal Doxorubicin and MR-HIFU for Pediatric Refractory Solid Tumors
AeRang Kim
NCT03009201 COMPLETED
Ribociclib and Doxorubicin in Treating Patients With Metastatic or Advanced Soft Tissue Sarcomas That Cannot Be Removed by Surgery
OHSU Knight Cancer Institute
NCT03829436 COMPLETED
TPST-1120 as Monotherapy and in Combination With Nivolumab in Subjects With Advanced Cancers
Tempest Therapeutics
NCT03399448 TERMINATED
NY-ESO-1-redirected CRISPR (TCRendo and PD1) Edited T Cells (NYCE T Cells)
University of Pennsylvania
NCT04802070 COMPLETED
Study of Adoptive Immunotherapy in Relapsed and Non-resectable Sarcomas After Multimodal Treatment.
Prof. Franca Fagioli
NCT02890368 TERMINATED
Trial of Intratumoral Injections of TTI-621 in Subjects With Relapsed and Refractory Solid Tumors and Mycosis Fungoides
Pfizer
NCT04837677 COMPLETED
A Study of PRT1419 in Patients With Advanced Solid Tumors
Prelude Therapeutics
NCT02890758 COMPLETED
Phase I Trial of Universal Donor NK Cell Therapy in Combination With ALT803
Brenda Cooper, MD
NCT04430842 COMPLETED
Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S
Quadriga Biosciences, Inc.
NCT03612466 WITHDRAWN
A Dose Finding Study of CycloSam® Combined With External Beam Radiotherapy
Albert Einstein College of Medicine
NCT04861948 TERMINATED
IBI188 Combination Therapy in Solid Tumors
Innovent Biologics (Suzhou) Co. Ltd.
NCT03209869 WITHDRAWN
Treatment of Relapsed or Refractory Neuroblastoma and Osteosarcoma With Expanded Haploidentical NK Cells and Hu14.18-IL2
University of Wisconsin, Madison
NCT01061411 COMPLETED
Dalteparin and Sunitinib Malate as First-Line Therapy in Treating Patients With Kidney Cancer That is Metastatic or Cannot Be Removed by Surgery
Roswell Park Cancer Institute
NCT00634504 COMPLETED
Open-label Leucovorin Pharmacokinetic Study in Patients Receiving High Dose Methotrexate With or Without Voraxaze
BTG International Inc.
NCT01061840 COMPLETED
Trial of Bi-shRNA-furin and GMCSF Augmented Autologous Tumor Cell Vaccine for Advanced Cancer
Gradalis, Inc.
NCT02982941 COMPLETED
Enoblituzumab (MGA271) in Children With B7-H3-expressing Solid Tumors
MacroGenics
NCT02573259 COMPLETED
A Dose Escalation Study Of PF-06801591 In Melanoma, Head And Neck Cancer (SCCHN), Ovarian, Sarcoma, Non-Small Cell Lung Cancer, Urothelial Carcinoma or Other Solid Tumors
Pfizer
NCT03042819 COMPLETED
Study of Selinexor and Doxorubicin in Advanced Soft Tissue Sarcomas
University Health Network, Toronto
NCT01353625 COMPLETED
Study to Assess Safety and Tolerability of Oral CC-115 for Patients With Advanced Solid Tumors, and Hematologic Malignancies.
Celgene
NCT03056599 COMPLETED
Precise Local Injection of Anti-cancer Drugs Using Presage's CIVO Device in Soft Tissue Sarcoma
Presage Biosciences
NCT02398058 COMPLETED
Trabectedin Plus Olaparib in Metastatic or Advanced Sarcomas (TOMAS)
Italian Sarcoma Group
NCT03730077 TERMINATED
FMISO PET/CT Imaging Trial for Assessing Hypoxia in Soft Tissue Sarcomas
University of Pennsylvania
NCT02748135 COMPLETED
A Study of TB-403 in Pediatric Subjects With Relapsed or Refractory Medulloblastoma
Oncurious NV
NCT02044120 COMPLETED
ESP1/SARC025 Global Collaboration: A Phase I Study of a Combination of the PARP Inhibitor, Niraparib and Temozolomide and/or Irinotecan Patients With Previously Treated, Incurable Ewing Sarcoma
Sarcoma Alliance for Research through Collaboration
NCT03139331 COMPLETED
PAZIT Study for Children and Young Adults With Relapsed or Refractory Sarcoma
University of California, San Francisco
NCT03782363 WITHDRAWN
Study of Adoptive Immunotherapy in Relapsed and Non-resectable Sarcomas After Multimodal Treatment.
Italian Sarcoma Group
NCT02343172 COMPLETED
Study of Safety and Efficacy of HDM201 in Combination With LEE011 in Patients With Liposarcoma
Novartis Pharmaceuticals
NCT03880123 WITHDRAWN
Selinexor in Combination With Ixazomib for the Treatment of Advanced Sarcoma
Matthew Ingham
NCT01433068 COMPLETED
NBTXR3 Crystalline Nanoparticles and Radiation Therapy in Treating Patients With Soft Tissue Sarcoma of the Extremity
Nanobiotix
NCT03283696 COMPLETED
A Study of Olaratumab (LY3012207), Doxorubicin, and Ifosfamide in Participants With Advanced or Metastatic Soft Tissue Sarcoma
Eli Lilly and Company
NCT02387125 TERMINATED
Phase 1b Safety Study of CMB305 in Patients With Locally Advanced, Relapsed, or Metastatic Cancer Expressing NY-ESO-1
Immune Design, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
NCT02223052 COMPLETED
Bioequivalence & Food Effect Study in Patients With Solid Tumor or Hematologic Malignancies
Celgene
NCT01916135 COMPLETED
PET Imaging of Cancer Patients Using [18F]-SKI-249380, a Radiolabeled Dasatinib-Derivative
Memorial Sloan Kettering Cancer Center
NCT02390843 COMPLETED
Simvastatin With Topotecan and Cyclophosphamide in Relapsed and/or Refractory Pediatric Solid and CNS Tumors
Emory University
NCT01143545 TERMINATED
Pilot Study of Allogeneic Tumor Cell Vaccine With Metronomic Oral Cyclophosphamide and Celecoxib in Patients Undergoing Resection of Lung and Esophageal Cancers, Thymic Neoplasms, and Malignant Pleural Mesotheliomas
National Cancer Institute (NCI)
NCT01313429 TERMINATED
Tumor Cell Vaccine for Patients Undergoing Surgery for Sarcomas, Melanomas, Germ Cell Tumors, or Malignancies That Have Metastasized to the Lungs, Pleura, or Mediastinum
National Cancer Institute (NCI)
NCT02576665 TERMINATED
A Study of Toca 511, a Retroviral Replicating Vector, Combined With Toca FC in Patients With Solid Tumors or Lymphoma (Toca 6)
Tocagen Inc.
NCT01447056 COMPLETED
Most Closely HLA-Matched CTLs for Relapsed Epstein Barr Virus(EBV)-Associated Diseases
Baylor College of Medicine
NCT01222780 COMPLETED
To Evaluate the Safety, Activity and Pharmacokinetics of Marqibo in Children and Adolescents With Refractory Cancer
Acrotech Biopharma Inc.
NCT02326025 COMPLETED
A Study of Olaratumab and Doxorubicin in Participants With Advanced Soft Tissue Sarcoma
Eli Lilly and Company
NCT02180698 COMPLETED
TLR4 Agonist GLA-SE and Radiation Therapy in Treating Patients With Soft Tissue Sarcoma That Is Metastatic or Cannot Be Removed by Surgery
Fred Hutchinson Cancer Center
NCT02795819 TERMINATED
Study of the Pan-DAC Inhibitor AR-42 and Pazopanib in Advanced Sarcoma and Kidney Cancer
Virginia Commonwealth University
NCT01375699 COMPLETED
Doxorubicin With or Without Sildenafil, With Analysis of Cardiac Markers
Virginia Commonwealth University
NCT02783599 COMPLETED
A Study of Olaratumab (LY3012207) in Participants With Soft Tissue Sarcoma
Eli Lilly and Company
NCT02565758 COMPLETED
ABBV-085, an Antibody Drug Conjugate, in Subjects With Advanced Solid Tumors
AbbVie
NCT02557854 WITHDRAWN
HIFU Hyperthermia With Liposomal Doxorubicin (DOXIL) for Relapsed or Refractory Pediatric and Young Adult Solid Tumors
Theodore Laetsch
NCT03437070 WITHDRAWN
Trabectedin, Doxorubicin and Olaratumab in Patients With Metastatic or Recurrent Leiomyosarcoma
University of Miami
NCT02122861 COMPLETED
Phase 1 Study of Intradermal LV305 in Patients With Locally Advanced, Relapsed or Metastatic Cancer Expressing NY-ESO-1
Immune Design, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
NCT01286987 COMPLETED
Study of Talazoparib, a PARP Inhibitor, in Patients With Advanced or Recurrent Solid Tumors
Pfizer
NCT00822848 COMPLETED
Sorafenib, Epirubicin, Ifosfamide, and Radiation Therapy Followed By Surgery in Treating Patients With High-Risk Stage II or Stage III Soft Tissue Sarcoma
OHSU Knight Cancer Institute
NCT01438554 COMPLETED
Phase 1 Study of Pazopanib With GSK1120212 in Advanced Solid Tumors, Enriched With Patients With Differentiated Thyroid Cancer, Soft-tissue Sarcoma, and Cholangiocarcinoma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT01106872 COMPLETED
Bevacizumab, Chemotherapy and Valproic Acid in Advanced Sarcomas
Mohammed M Milhem
NCT01341496 TERMINATED
Tumor Cell Vaccines and ISCOMATRIX With Chemotherapy After Tumor Removal
National Cancer Institute (NCI)
NCT02839694 WITHDRAWN
Adjuvant Oral Decitabine and Tetrahydrouridine With or Without Celecoxib in People Undergoing Pulmonary Metastasectomy
National Cancer Institute (NCI)
NCT00931931 COMPLETED
HSV1716 in Patients With Non-Central Nervous System (Non-CNS) Solid Tumors
Timothy Cripe
NCT01016730 COMPLETED
Bortezomib in Treating Patients With Relapsed or Refractory AIDS-Related Kaposi Sarcoma
National Cancer Institute (NCI)
NCT02014337 COMPLETED
Mifepristone and Eribulin in Patients With Metastatic Triple Negative Breast Cancer or Other Specified Solid Tumors
Corcept Therapeutics
NCT01012362 TERMINATED
Study of Pazopanib and Ixabepilone in Patients With Solid Tumors
Masonic Cancer Center, University of Minnesota
NCT00703638 COMPLETED
Sorafenib, Pemetrexed, and Cisplatin in Treating Patients With Advanced Solid Tumors
Masonic Cancer Center, University of Minnesota
NCT03007771 WITHDRAWN
Magnetic Resonance-guided High-Intensity Focused Ultrasound (MR-HIFU) Used for Mild Hyperthermia
Washington University School of Medicine
NCT01498835 COMPLETED
Safety Study of Preoperative Sunitinib and Radiation in Soft Tissue Sarcoma
Heidelberg University
NCT02015416 COMPLETED
A Phase 1 Trial of NY-ESO-1 With GLA-SE in Patients With Unresectable or Metastatic Cancer
Immune Design, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
NCT00743496 COMPLETED
A Phase I Trial Of The Humanized Anti-GD2 Antibody In Children And Adolescents With Neuroblastoma, Osteosarcoma, Ewing Sarcoma and Melanoma
St. Jude Children's Research Hospital
NCT02210104 WITHDRAWN
Adoptive Therapy Using Antigen-Specific CD4 T-Cells
M.D. Anderson Cancer Center
NCT02319824 COMPLETED
NY-ESO-1-Specific T-cells in Treating Patients With Advanced NY-ESO-1-Expressing Sarcomas Receiving Palliative Radiation Therapy
Fred Hutchinson Cancer Center
NCT01130623 WITHDRAWN
A Phase I Study of Pazopanib as a Single Agent for Children With Refractory Solid Tumors
National Cancer Institute (NCI)
NCT01236586 WITHDRAWN
RO4929097 in Children With Relapsed/Refractory Solid or CNS Tumors, Lymphoma, or T-Cell Leukemia
National Cancer Institute (NCI)
NCT01386502 WITHDRAWN
CT-011 and p53 Genetic Vaccine for Advanced Solid Tumors
National Cancer Institute (NCI)
NCT01132911 COMPLETED
A Phase I Study of Vorinostat and Bortezomib in Children With Refractory of Recurrent Solid Tumors, Including CNS Tumors and Lymphomas
National Cancer Institute (NCI)
NCT01469975 TERMINATED
First in Man Study Investigating the Biodistribution, the Safety and Optimal Recommended Dose of a New Radiolabelled Monoclonal Antibody Targeting Frizzled Homolog 10
Centre Leon Berard
NCT02472392 COMPLETED
Study To Examine Toxicity Of Allogeneic Stem Cell Transplantation For Relapsed Or Therapy Refractory Ewings Sarcoma
University of Louisville
NCT01241162 COMPLETED
Decitabine Followed by a Cancer Antigen Vaccine for Patients With Neuroblastoma and Sarcoma
University of Louisville
NCT01969942 WITHDRAWN
A Phase I Study to Examine the Toxicity of Allogeneic Stem Cell Transplantation for Relapsed or Therapy Refractory Ewing Sarcoma
University of Louisville
NCT01537744 COMPLETED
A Trial of Oral 5-azacitidine in Combination With Romidepsin in Advanced Solid Tumors, With an Expansion Cohort in Virally Mediated Cancers and Liposarcoma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT01005797 COMPLETED
Study of Panobinostat in Combination With Sorafenib in Kidney, Soft Tissue or Lung Cancers
Medical University of South Carolina
NCT01643278 COMPLETED
Dasatinib and Ipilimumab in Treating Patients With Gastrointestinal Stromal Tumors or Other Sarcomas That Cannot Be Removed by Surgery or Are Metastatic
National Cancer Institute (NCI)
NCT01204450 TERMINATED
Temsirolimus and Valproic Acid in Treating Young Patients With Relapsed Neuroblastoma, Bone Sarcoma, or Soft Tissue Sarcoma
UNC Lineberger Comprehensive Cancer Center
NCT01143740 COMPLETED
A Study of RO5045337 in Patients With Liposarcomas Prior to Debulking Surgery
Hoffmann-La Roche
NCT01605526 COMPLETED
A Study of RO5045337 in Combination With Doxorubicin in Patients With Soft Tissue Sarcoma
Hoffmann-La Roche
NCT01522820 COMPLETED
Vaccine Therapy With or Without Sirolimus in Treating Patients With NY-ESO-1 Expressing Solid Tumors
Roswell Park Cancer Institute
NCT01155258 COMPLETED
Temsirolimus and Vinorelbine Ditartrate in Treating Patients With Unresectable or Metastatic Solid Tumors
University of Southern California
NCT02464332 WITHDRAWN
Safety Study of BLZ-100 in Adult Subjects With Sarcoma Undergoing Surgery
Blaze Bioscience Inc.
NCT00720174 COMPLETED
Cixutumumab and Doxorubicin Hydrochloride in Treating Patients With Unresectable, Locally Advanced, or Metastatic Soft Tissue Sarcoma
National Cancer Institute (NCI)
NCT02059850 WITHDRAWN
NY-ESO-1 Specific T Cells After Cyclophosphamide in Treating Patients With Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma
Fred Hutchinson Cancer Center
NCT01169584 COMPLETED
Safety Study of Recombinant Vaccinia Virus to Treat Refractory Solid Tumors in Pediatric Patients
Jennerex Biotherapeutics
NCT01985295 COMPLETED
Combined Modality Treatment of Sarcomas of the Extremities
The Netherlands Cancer Institute
NCT01548482 COMPLETED
Trebananib And Temsirolimus in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery
National Cancer Institute (NCI)
NCT00996346 TERMINATED
Phase I/II Study of Irinotecan and Temsirolimus in Patients With Refractory Sarcomas
New Mexico Cancer Research Alliance
NCT01652794 COMPLETED
Carboplatin, Gemcitabine Hydrochloride, and Stereotactic Body Radiation Therapy in Gynecological Cancer
Case Comprehensive Cancer Center
NCT01598454 COMPLETED
Use of Racotumomab in Patients With Pediatric Tumors Expressing N-glycolylated Gangliosides
Laboratorio Elea Phoenix S.A.
NCT00427414 TERMINATED
Liposomal Daunorubicin in Treating Patients With HIV-Related Kaposi's Sarcoma
AIDS Malignancy Consortium
NCT01518413 COMPLETED
Dose Escalation Study of Sorafenib and Irinotecan Combination Therapy in Pediatric Patients With Solid Tumors
HMeany
NCT01426633 COMPLETED
Combination Therapy of Gemcitabine and Trabectedin in L-sarcomas
Heidelberg University
NCT01477021 COMPLETED
Autologous T Cells and Cyclophosphamide in Treating Patients With Soft Tissue Sarcoma That is Metastatic or Cannot Be Removed By Surgery
Fred Hutchinson Cancer Center
NCT00742924 COMPLETED
Zoledronic Acid and Combination Chemotherapy in Treating Patients With Newly Diagnosed Metastatic Osteosarcoma
Children's Oncology Group
NCT00609141 COMPLETED
IMC-A12 in Treating Young Patients With Relapsed or Refractory Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor or Other Solid Tumor
National Cancer Institute (NCI)
NCT01491594 TERMINATED
Eltrombopag for the Prevention of Chemotherapy Induced Thrombocytopenia
Duke University
NCT01048892 COMPLETED
Seneca Valley Virus-001 and Cyclophosphamide in Treating Young Patients With Relapsed or Refractory Neuroblastoma, Rhabdomyosarcoma, or Rare Tumors With Neuroendocrine Features
Children's Oncology Group
NCT01479023 TERMINATED
Evaluation of 64Cu-DOTA-U3-1287 in Subjects With Advanced Solid Tumors
Washington University School of Medicine
NCT01258634 TERMINATED
A Study of Pre-Operative Treatment of Newly-Diagnosed, Surgically-Resectable Osteosarcoma With Doxorubicin, Ifosfamide, Etoposide, and Cisplatin With Early Metabolic Assessment of Response
University of Chicago
NCT00927966 COMPLETED
RAD001 in Combination With CP-751,871 in Patients Wtih Advanced Sarcomas and Other Malignant Neoplasms
Suzanne George, MD
NCT00929903 COMPLETED
Pazopanib Hydrochloride in Treating Young Patients With Solid Tumors That Have Relapsed or Not Responded to Treatment
National Cancer Institute (NCI)
NCT00842452 COMPLETED
Topotecan in Treating Patients With Gynecologic Cancer That Cannot Be Removed by Surgery
Steven Waggoner, MD
NCT01296659 WITHDRAWN
Study of Oral Ridaforolimus in Combination With Standard Chemotherapy for Soft Tissue Sarcoma
The University of Texas Health Science Center at San Antonio
NCT03144206 ACTIVE NOT RECRUITING
Hyperbaric Oxygen Therapy for Soft Tissue Sarcoma Pilot Study
Duke University
NCT04033081 ACTIVE NOT RECRUITING
Registry of Sarcoma Patients Treated With Permanently Implantable LDR CivaSheet®
CivaTech Oncology
NCT03244020 ENROLLING BY INVITATION
LMWH vs Aspirin for VTE Prophylaxis in Orthopaedic Oncology
Massachusetts General Hospital
NCT06506838 RECRUITING
Anlotinib Combined With Doxorubicin and Radiotherapy as Neoadjuvant Treatment for Soft Tissue Sarcoma
Guangdong Provincial People's Hospital
NCT06236022 RECRUITING
The Effects of Sirolimus in Patients With Dilated Cardiomyopathy Infected With Kaposi Sarcoma-associated Virus
Tongji Hospital
NCT05844813 ENROLLING BY INVITATION
Neoadjuvant Chemotherapy Combined With Targeted Treatment in High-risk Retroperitoneal Sarcoma
Peking University International Hospital
NCT03514381 COMPLETED
Pharmacologic Interaction Between Ifosfamide and Aprepitant in Treated Patients With Soft Tissue Sarcoma
Institut Claudius Regaud
NCT04347122 TERMINATED
Tranexamic Acid in Radical Resection and Endoprosthetic Reconstruction
University of Kansas Medical Center
NCT04854018 COMPLETED
Indo-cyanine Green (ICG) in Paediatric Oncology MIS
Birmingham Women's and Children's NHS Foundation Trust
NCT03735758 TERMINATED
Quality of Life in Patients With Non-adipocyte Soft Tissue Sarcoma Under Palliative Chemotherapy or Pazopanib
GWT-TUD GmbH
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