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Data updated: May 26, 2026

CALCIPOTRIENE AND BETAMETHASONE DIPROPIONATE (betamethasone dipropionate)

Immunology Approved 2013-01-14

This topical ointment treats plaque psoriasis in patients 12 years of age and older. It combines a synthetic vitamin D3 analogue with a corticosteroid to help patients manage their skin symptoms. Healthcare providers use this combination product to address the physical effects of plaque psoriasis through a dual-action approach.

Source: FDA Label • SUN PHARMA CANADA • Vitamin D Analog

How CALCIPOTRIENE AND BETAMETHASONE DIPROPIONATE Works

This medication works by combining the pharmacological effects of calcipotriene and betamethasone dipropionate. While the exact biological mechanisms that improve plaque psoriasis are unknown, the drug utilizes the properties of both a synthetic vitamin D3 analogue and a synthetic corticosteroid.

Source: FDA Label
5
Indications
--
Phase 3 Trials
13
Years on Market

Details

Status
Prescription
First Approved
2013-01-14
Routes
TOPICAL
Dosage Forms
SUSPENSION, OINTMENT, AEROSOL, FOAM

CALCIPOTRIENE AND BETAMETHASONE DIPROPIONATE Approval History

2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
9 FDA actions from 2013 to 2023
Mar 2023 ORIGINAL
Update
Sep 2020 ORIGINAL
Update
May 2020 ORIGINAL
Update

What CALCIPOTRIENE AND BETAMETHASONE DIPROPIONATE Treats

1 indications

CALCIPOTRIENE AND BETAMETHASONE DIPROPIONATE is approved for 1 conditions since its original approval in 2013. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Plaque Psoriasis
Source: FDA Label

CALCIPOTRIENE AND BETAMETHASONE DIPROPIONATE Competitive Set

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Filters applied: drops same-active-ingredient (505(b)(2) reformulations), route-mismatch (topical vs systemic), and cross-therapeutic-area matches in same-indication rings.

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Clinical Trial Registry

1 trials
Trial Sponsor ID Phase Status Title
NCT06332612 MROSF 8420224AROM Ph 1, Ph 2 completed Metformin Repurposing in Oral Submucous Fibrosis: Unveiling In Vitro Signaling Pathways, Progressing to Clinical Trial
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Active Pipeline

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Key Completed Trials

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

CALCIPOTRIENE AND BETAMETHASONE DIPROPIONATE FDA Label Details

Indications & Usage

CALCIPOTRIENE AND BETAMETHASONE DIPROPIONATE is indicated for the treatment of Plaque Psoriasis.

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.