TheraRadar
Data updated: May 26, 2026

DILTIAZEM HYDROCHLORIDE IN 0.72% SODIUM CHLORIDE (diltiazem hydrochloride)

Cardiovascular Approved 2025-02-21

DILTIAZEM HYDROCHLORIDE IN 0.72% SODIUM CHLORIDE is indicated for the treatment of Hypertension; Angina; Coronary Artery Spasm.

Source: FDA Label • HQ SPCLT PHARMA
1
Indication
--
Phase 3 Trials
1
Years on Market

Details

Status
Prescription
First Approved
2025-02-21
Routes
INTRAVENOUS
Dosage Forms
SOLUTION

Companies

Active Ingredient: DILTIAZEM HYDROCHLORIDE

DILTIAZEM HYDROCHLORIDE IN 0.72% SODIUM CHLORIDE Approval History

2026
Original
New Indication
New Form
Label Update
2 FDA actions from 2025 to 2025
Feb 2025 ORIGINAL
Update · Type 5 - New Formulation or New Manufacturer

What DILTIAZEM HYDROCHLORIDE IN 0.72% SODIUM CHLORIDE Treats

3 indications

DILTIAZEM HYDROCHLORIDE IN 0.72% SODIUM CHLORIDE is approved for 3 conditions since its original approval in 2025. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Hypertension
  • Angina
  • Coronary Artery Spasm
Source: FDA Label

DILTIAZEM HYDROCHLORIDE IN 0.72% SODIUM CHLORIDE Competitive Set

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Filters applied: drops same-active-ingredient (505(b)(2) reformulations), route-mismatch (topical vs systemic), and cross-therapeutic-area matches in same-indication rings.

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Clinical Trial Registry

2 trials
Trial Sponsor ID Phase Status Title
NCT07456852 MC250411 NCI-2026-01065, MC250411 Ph 1, Ph 2 not yet recruiting Vasodilator Therapy With Isosorbide Mononitrate or Diltiazem to Reduce Vasotoxicity in Patients With Gastrointestinal Cancer Receiving Fluoropyrimidine Therapy
NCT04777045 EDIT-CMD NL67497.091.19 2018-003518-41 Ph 3 active not recruiting Efficacy of Diltiazem to Improve Coronary Microvascular Dysfunction: a Randomized Clinical Trial
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Active Pipeline

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Key Completed Trials

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

DILTIAZEM HYDROCHLORIDE IN 0.72% SODIUM CHLORIDE FDA Label Details

Indications & Usage

FDA Label (PDF)

DILTIAZEM HYDROCHLORIDE IN 0.72% SODIUM CHLORIDE is indicated for the treatment of Hypertension; Angina; Coronary Artery Spasm.

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.