TheraRadar
Data updated: May 26, 2026

FLUORESCITE (fluorescein sodium)

Ophthalmology Approved 2006-03-28

FLUORESCITE Injection 10% is indicated in diagnostic fluorescein angiography or angioscopy of the retina and iris vasculature.

Source: FDA Label • Novartis
1
Indication
--
Phase 3 Trials
1
Priority Reviews
20
Years on Market

Details

Status
Prescription
First Approved
2006-03-28
Routes
INTRAVENOUS
Dosage Forms
INJECTABLE

Companies

Active Ingredient: FLUORESCEIN SODIUM

FLUORESCITE Approval History

2007
2008
2009
2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
5 FDA actions from 2006 to 2021
Nov 2021 SUPPL
Label · Labeling
Feb 2016 SUPPL
Label · Labeling
Feb 2015 SUPPL Priority
Mfg · Manufacturing (CMC)

What FLUORESCITE Treats

1 FDA approvals

Originally approved for its first indication in 2006 .

  • Other (1)
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Clinical Trial Registry

8 trials
Trial Sponsor ID Phase Status Title
NCT06873815 25-002 Ph 2 recruiting A Study of Fluorescein Sodium in People Undergoing Vulvectomy for Extramammary Paget's Disease (EMPD)
NCT06054178 results posted 71857 R25DC020174-03 Ph 2 completed Identification of Nerves Using Fluorescein Sodium
NCT05664555 DOSE B-2211-790-004 Ph 4 completed Dose Optimization for Safe and Efficient Fluorescein Angiography (DOSE Study)
NCT04351373 results posted 19-005178 Ph 2 completed Microscopic Fluorescence-guided Vestibular Schwannoma Resection Using Fluorescein Sodium and YELLOW 560
NCT04017975 OPTIMA P00031701 R56HL128813 Ph 2 active not recruiting Optical Tissue Identification for Myocardial Architecture
NCT03189134 results posted P00013570 R56HL128813 Ph 1 completed Utilization of Confocal Microscopy During Cardiac Surgery
NCT04071080 PH1.20180001 Ph 1 completed The Study of Oral Fluorescite to Confirm the Authenticity of Point of Care Urine Samples
NCT02028325 Fluorescein results posted GCBS-0003 Ph 4 terminated Yellow 560 Microscope for Intraoperative Visualization of Fluorescein Stained Intracranial Lesions
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Active Pipeline

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Ongoing clinical trials by development phase

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Key Completed Trials

Pro

Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

FLUORESCITE FDA Label Details

Indications & Usage

FDA Label (PDF)

FLUORESCITE ® Injection 10% is indicated in diagnostic fluorescein angiography or angioscopy of the retina and iris vasculature. FLUORESCITE ® Injection 10% is indicated in diagnostic fluorescein angiography or angioscopy of the retina and iris vasculature.

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.