TheraRadar
Data updated: May 26, 2026

GOZELLIX (gallium ga-68 gozetotide)

Trial Activity: Declining 1 active trials
Oncology Approved 2025-03-20

Gozellix is a diagnostic imaging agent used for PET scans in men with prostate cancer. It helps clinicians identify prostate-specific membrane antigen (PSMA) positive lesions in patients who are suspected of having cancer that has spread before they begin their initial definitive treatment. It is also used for patients who may have a cancer recurrence, often signaled by an increase in PSA levels.

Source: FDA Label • TELIX INNOVATIONS

How GOZELLIX Works

This agent works by targeting and binding to PSMA, a protein frequently overexpressed on the surface of malignant prostate cancer cells. Because it contains gallium-68, a radioactive radionuclide, it allows for the visualization of these cancer cells during positron emission tomography (PET).

Development Insights

Mayo Clinic conducting 3 trials (50%)
19 indications explored (Broad Platform)
stage ivb prostate cancer ajcc v8 (3 trials)
castration-resistant prostate carcinoma (2 trials)
metastatic prostate carcinoma (2 trials)
1
Indication
--
Phase 3 Trials
1
Years on Market

Details

Status
Prescription
First Approved
2025-03-20
Patent Cliff
2035

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Routes
INTRAVENOUS
Dosage Forms
POWDER

Companies

Active Ingredient: GALLIUM GA-68 GOZETOTIDE

GOZELLIX Approval History

2026
Original
New Indication
New Form
Label Update
1 FDA actions from 2025 to 2025
Mar 2025 ORIGINAL
Update · Type 5 - New Formulation or New Manufacturer

What GOZELLIX Treats

3 indications

GOZELLIX is approved for 3 conditions since its original approval in 2025. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Prostate Cancer
  • Metastasis
  • Recurrence
Source: FDA Label

GOZELLIX Competitive Set

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Filters applied: drops same-active-ingredient (505(b)(2) reformulations), route-mismatch (topical vs systemic), and cross-therapeutic-area matches in same-indication rings.

What's emerging in GOZELLIX's indications

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Phase 3 candidates targeting molecules with no FDA-approved drug, in indications GOZELLIX treats. First-in-class if their pivotal trials read out positive.

Drugs Similar to GOZELLIX

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FDA-approved drugs for similar conditions. Compare mechanisms and indications to understand treatment alternatives.

GALLIUM GA-68 GOZETOTIDE
GALLIUM GA-68 GOZETOTIDE
3 shared
IONETIX
Shared indications:
Prostate CancerMetastasisRecurrence
ILLUCCIX
GALLIUM GA-68 GOZETOTIDE
3 shared
TELIX
Shared indications:
Prostate CancerMetastasisRecurrence
LOCAMETZ
GALLIUM GA-68 GOZETOTIDE
3 shared
Novartis
Shared indications:
Prostate CancerMetastasisRecurrence
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Active Pipeline

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Key Completed Trials

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Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

GOZELLIX FDA Label Details

Indications & Usage

FDA Label (PDF)

GOZELLIX is indicated for the treatment of Prostate Cancer; Metastasis; Recurrence.

View full patent landscape →
1 OB patents · 1 families · 4 international docs across 1 countries

GOZELLIX Patents & Exclusivity

Latest Patent: Jul 2035

Patents (1 active)

US11027031 Expires Jul 28, 2035
Source: FDA Orange Book

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Deep insights for GOZELLIX

Revenue Insights

  • Quarterly revenue tracking
  • Historical trend analysis

Patent Timeline

  • Cliff: 2035
  • 1 active patents

Trial Analysis

  • 6 total trials
  • Stage: Declining

Competitive Landscape

  • 20 similar drugs
  • Same target/indication analysis
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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.

How We Calculate These Metrics

Trial Activity Stage

Measures the current development activity pattern based on trial phases, status, and trends. Important: This measures R&D activity, not commercial lifecycle.

Trial statuses: "Active" means recruiting or ongoing. "Completed" means reached planned endpoint. "Terminated" means stopped early—often due to safety, efficacy, or business reasons.

  • Growth: High proportion of early-phase trials (Phase 1/2), active development
  • Expansion: Significant Phase 3 activity, approaching or pursuing approvals
  • Mature: Substantial Phase 4 post-marketing studies
  • Stable: Mixed phase distribution, steady development
  • Declining: Low active trial ratio, reduced R&D investment