MYDRIACYL (tropicamide)
MYDRIACYL is indicated for the treatment of Mydriasis; Cycloplegia.
Development Insights
Details
- Status
- Discontinued
- First Approved
- 1960-02-23
- Routes
- OPHTHALMIC
- Dosage Forms
- SOLUTION/DROPS
MYDRIACYL Approval History
What MYDRIACYL Treats
2 indicationsMYDRIACYL is approved for 2 conditions since its original approval in 1960. These indications span multiple therapeutic areas including oncology, immunology, and more.
- Mydriasis
- Cycloplegia
MYDRIACYL Competitive Set
ProThree rings of competition based on shared molecular targets and treated indications.
Indication competitors
Same indication, different mechanism — what else might this patient receive?
Filters applied: drops same-active-ingredient (505(b)(2) reformulations), route-mismatch (topical vs systemic), and cross-therapeutic-area matches in same-indication rings.
Drugs Similar to MYDRIACYL
3 of 6FDA-approved drugs for similar conditions. Compare mechanisms and indications to understand treatment alternatives.
Clinical Trial Registry
4 trials| Trial | Sponsor ID | Phase | Status | Title |
|---|---|---|---|---|
| NCT03959176 results posted | IRB00058366 | Ph 4 | completed | The Effect of Brimonidine |
| NCT05238233 results posted | 1864081 | Ph 4 | completed | Wearing-Off Period of Pharmacological Dilation and Anisocoria |
| NCT05442801 | Cycloplegic Refraction | Ph 4 | completed | Cycloplegic Refraction Among Children |
| NCT03139708 | IRB00039213 | Ph 1 | completed | The Effect of Brimonidine on Intraocular Pressure When Dilating Routine Patients |
Active Pipeline
Ongoing clinical trials by development phase
Key Completed Trials
Completed studies with published results, ranked by significance
Trial Timeline
Full development history with FDA approval milestones
Understanding FDA Approval Types
| Count | Type | What it means |
|---|---|---|
| - | ORIG | Original approval - drug first enters market |
| - | SUPPL - Efficacy | New indication (new disease/condition approved) |
| - | SUPPL - Labeling | Label text changes (warnings, dosing updates) |
| - | SUPPL - Manufacturing | Production changes (new facility) |
| - | SUPPL - Chemistry | Formulation changes (new dosage strength) |
Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.
MYDRIACYL FDA Label Details
Indications & Usage
MYDRIACYL is indicated for the treatment of Mydriasis; Cycloplegia.
Track MYDRIACYL with TheraRadar Pro
Watchlist alerts, full database access, CSV exports across 14,000+ drugs.
Data Sources
Data sourced from official FDA and NIH databases. Click links to verify on original sources.
How We Calculate These Metrics
Trial Activity Stage
Measures the current development activity pattern based on trial phases, status, and trends. Important: This measures R&D activity, not commercial lifecycle.
Trial statuses: "Active" means recruiting or ongoing. "Completed" means reached planned endpoint. "Terminated" means stopped early—often due to safety, efficacy, or business reasons.
- Growth: High proportion of early-phase trials (Phase 1/2), active development
- Expansion: Significant Phase 3 activity, approaching or pursuing approvals
- Mature: Substantial Phase 4 post-marketing studies
- Stable: Mixed phase distribution, steady development
- Declining: Low active trial ratio, reduced R&D investment