PYZCHIVA (ustekinumab-ttwe)
PYZCHIVA is indicated for the treatment of Plaque Psoriasis; Psoriatic Arthritis; Crohn's Disease; Ulcerative Colitis.
Details
- Status
- Prescription
- First Approved
- 2024-06-28
- Routes
- INJECTION, SUBCUTANEOUS
- Dosage Forms
- INJECTABLE
PYZCHIVA Approval History
What PYZCHIVA Treats
4 indicationsPYZCHIVA is approved for 4 conditions since its original approval in 2024. These indications span multiple therapeutic areas including oncology, immunology, and more.
- Plaque Psoriasis
- Psoriatic Arthritis
- Crohn's Disease
- Ulcerative Colitis
Pharmacists can substitute PYZCHIVA for Stelara without calling the prescriber. This is a lower-cost alternative with no clinically meaningful differences.
PYZCHIVA Competitive Set
ProThree rings of competition based on shared molecular targets and treated indications.
Indication competitors
Same indication, different mechanism — what else might this patient receive?
Filters applied: drops same-active-ingredient (505(b)(2) reformulations), route-mismatch (topical vs systemic), and cross-therapeutic-area matches in same-indication rings.
What's emerging in PYZCHIVA's indications
See all emerging drugs →Phase 3 candidates targeting molecules with no FDA-approved drug, in indications PYZCHIVA treats. First-in-class if their pivotal trials read out positive.
Drugs Similar to PYZCHIVA
3 of 20FDA-approved drugs for similar conditions. Compare mechanisms and indications to understand treatment alternatives.
Active Pipeline
Ongoing clinical trials by development phase
Key Completed Trials
Completed studies with published results, ranked by significance
Trial Timeline
Full development history with FDA approval milestones
Understanding FDA Approval Types
| Count | Type | What it means |
|---|---|---|
| - | ORIG | Original approval - drug first enters market |
| - | SUPPL - Efficacy | New indication (new disease/condition approved) |
| - | SUPPL - Labeling | Label text changes (warnings, dosing updates) |
| - | SUPPL - Manufacturing | Production changes (new facility) |
| - | SUPPL - Chemistry | Formulation changes (new dosage strength) |
Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.
PYZCHIVA FDA Label Details
Indications & Usage
FDA Label (PDF)PYZCHIVA is indicated for the treatment of Plaque Psoriasis; Psoriatic Arthritis; Crohn's Disease; Ulcerative Colitis.
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Data Sources
Data sourced from official FDA and NIH databases. Click links to verify on original sources.