Data updated: May 26, 2026
VERAPAMIL HYDROCHLORIDE
Cardiovascular
Approved 1984-03-30
VERAPAMIL HYDROCHLORIDE is indicated for the treatment of Angina; Atrial Flutter; Atrial Fibrillation; Supraventricular Tachycardia; Hypertension.
Source: FDA Label • EXELA PHARMA
43
Indications
--
Phase 3 Trials
42
Years on Market
Details
- Status
- Discontinued
- First Approved
- 1984-03-30
- Routes
- INTRAVENOUS, INJECTION, ORAL
- Dosage Forms
- SOLUTION, INJECTABLE, TABLET, TABLET, EXTENDED RELEASE, CAPSULE, EXTENDED RELEASE
Companies
EXELA PHARMA ZYDUS PHARMS GLAND WARNER CHILCOTT MUTUAL PHARM Pfizer Teva BEDFORD Apotex PLIVA SOMERSET MANKIND PHARMA WATSON LABS CHARTWELL RX MICRO LABS Fresenius Kabi ABRAXIS PHARM SOLOPAK HERITAGE MARSAM PHARMS LLC STRIDES PHARMA INTL GLENMARK PHARMS LTD AMNEAL EUGIA PHARMA NEPHRON LUITPOLD Viatris SOMERSET THERAPS LLC ZYDUS LIFESCIENCES SMITH AND NEPHEW Sun Pharma RISING CADILA PHARMS LTD CAPLIN ASPIRO IVAX SUB TEVA PHARMS INTL MEDICATION
Active Ingredient: VERAPAMIL HYDROCHLORIDE
Website: ↗
VERAPAMIL HYDROCHLORIDE Approval History
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Original
New Indication
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Label Update
816 FDA actions from 1984 to 2025
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What VERAPAMIL HYDROCHLORIDE Treats
5 indicationsVERAPAMIL HYDROCHLORIDE is approved for 5 conditions since its original approval in 1984. These indications span multiple therapeutic areas including oncology, immunology, and more.
- Angina
- Atrial Flutter
- Atrial Fibrillation
- Supraventricular Tachycardia
- Hypertension
Source: FDA Label
VERAPAMIL HYDROCHLORIDE Competitive Set
ProThree rings of competition based on shared molecular targets and treated indications.
Indication competitors
10
Same indication, different mechanism — what else might this patient receive?
Unlock 8 more competitors across all three rings.
Upgrade to Pro Filters applied: drops same-active-ingredient (505(b)(2) reformulations), route-mismatch (topical vs systemic), and cross-therapeutic-area matches in same-indication rings.
What's emerging in VERAPAMIL HYDROCHLORIDE's indications
See all emerging drugs →Phase 3 candidates targeting molecules with no FDA-approved drug, in indications VERAPAMIL HYDROCHLORIDE treats. First-in-class if their pivotal trials read out positive.
Baxdrostat CIN-107 ✓ Won — Ph3 readout
AstraZeneca CYP11B2 · small-molecule selective aldosterone synthase inhibitor · 4 Phase 3 trials
Abelacimab MAA868 ~ Mixed — Ph3 readout
Anthos Therapeutics, Inc. F11 · monoclonal antibody (anti-FXI/FXIa) · 3 Phase 3 trials
REGN9933 REGN9933
Regeneron Pharmaceuticals F11 · monoclonal antibody (anti-FXI) · 2 Phase 3 trials
Lorundrostat MLS-101 ✓ Won — Ph3 readout
Mineralys Therapeutics Inc. CYP11B2 · small-molecule selective aldosterone synthase inhibitor · 2 Phase 3 trials
Zilebesiran ALN-AGT01
Alnylam Pharmaceuticals AGT · GalNAc-conjugated siRNA (RNAi therapeutic) · 1 Phase 3 trial
Drugs Similar to VERAPAMIL HYDROCHLORIDE
3 of 20FDA-approved drugs for similar conditions. Compare mechanisms and indications to understand treatment alternatives.
📋
Clinical Trial Registry
2 trials| Trial | Sponsor ID | Phase | Status | Title |
|---|---|---|---|---|
| NCT03013933 | 16414 NCI-2016-02062, 16414 | Ph 1 | completed | Brentuximab Vedotin, Cyclosporine, and Verapamil Hydrochloride in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma |
| NCT03098680 PRIME | PRIME (A094136) | Ph 1 | terminated | A Study of the Pharmacokinetic and Pharmacodynamic Responses in Healthy and Altered Human Cardiovascular Systems |
🔬
Pro Active Pipeline
Ongoing clinical trials by development phase
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Pro Key Completed Trials
Completed studies with published results, ranked by significance
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Trial Timeline
Full development history with FDA approval milestones
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Understanding FDA Approval Types
| Count | Type | What it means |
|---|---|---|
| - | ORIG | Original approval - drug first enters market |
| - | SUPPL - Efficacy | New indication (new disease/condition approved) |
| - | SUPPL - Labeling | Label text changes (warnings, dosing updates) |
| - | SUPPL - Manufacturing | Production changes (new facility) |
| - | SUPPL - Chemistry | Formulation changes (new dosage strength) |
Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.
VERAPAMIL HYDROCHLORIDE FDA Label Details
Indications & Usage
FDA Label (PDF)VERAPAMIL HYDROCHLORIDE is indicated for the treatment of Angina; Atrial Flutter; Atrial Fibrillation; Supraventricular Tachycardia; Hypertension.
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Data Sources
Data sourced from official FDA and NIH databases. Click links to verify on original sources.