TheraRadar
Data updated: May 26, 2026

LANREOTIDE ACETATE

Endocrine Approved 2021-12-17

LANREOTIDE ACETATE is indicated for the treatment of Acromegaly; Gastroenteropancreatic Neuroendocrine Tumors; Carcinoid Syndrome.

Source: FDA Label • INVAGEN PHARMS

How LANREOTIDE ACETATE Works

Lanreotide is an octapeptide analog of natural somatostatin. It acts as a somatostatin receptor agonist, with high affinity for human somatostatin receptors 2 and 5 (SSTR2 and SSTR5). By binding to these receptors, it inhibits the secretion of various hormones, including growth hormone (GH) and insulin-like growth factor-1 (IGF-1), and exerts anti-proliferative effects on neuroendocrine tumor cells.

3
Indications
--
Phase 3 Trials
4
Years on Market

Details

Status
Prescription
First Approved
2021-12-17
Routes
SUBCUTANEOUS
Dosage Forms
SOLUTION

Companies

Active Ingredient: LANREOTIDE ACETATE

LANREOTIDE ACETATE Approval History

2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
12 FDA actions from 2021 to 2024 · 1 indication expansions
Sep 2024 SUPPL
Efficacy
Jul 2024 SUPPL
Label · Labeling
May 2024 ORIGINAL
Update

What LANREOTIDE ACETATE Treats

3 indications

LANREOTIDE ACETATE is approved for 3 conditions since its original approval in 2021. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Acromegaly
  • Gastroenteropancreatic Neuroendocrine Tumors
  • Carcinoid Syndrome
Source: FDA Label

LANREOTIDE ACETATE Competitive Set

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Filters applied: drops same-active-ingredient (505(b)(2) reformulations), route-mismatch (topical vs systemic), and cross-therapeutic-area matches in same-indication rings.

Drugs Similar to LANREOTIDE ACETATE

3 of 11

FDA-approved drugs for similar conditions. Compare mechanisms and indications to understand treatment alternatives.

SOMATULINE DEPOT
LANREOTIDE ACETATE
3 shared
IPSEN PHARMA
Shared indications:
AcromegalyGastroenteropancreatic Neuroendocrine TumorsCarcinoid Syndrome
BYNFEZIA PEN
OCTREOTIDE ACETATE
1 shared
Sun Pharma
Shared indications:
Acromegaly
LUTATHERA
LUTETIUM LU 177 DOTATATE
1 shared
AAA USA INC
Shared indications:
Gastroenteropancreatic Neuroendocrine Tumors
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Clinical Trial Registry

2 trials
Trial Sponsor ID Phase Status Title
NCT02075606 CALM-NET results posted A-97-52030-270 2013-002194-22 Ph 4 completed Circulating Tumour Cells in Somatuline Autogel Treated NeuroEndocrine Tumours Patients
NCT02493517 LANTERN results posted 8-55-52030-289 CTR20140698 Ph 3 completed Efficacy and Safety of Lanreotide Autogel® 60, 90 or 120 mg With Lanreotide 40 mg Prolonged Release (PR) in Acromegaly
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Active Pipeline

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Ongoing clinical trials by development phase

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Key Completed Trials

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Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

LANREOTIDE ACETATE FDA Label Details

Indications & Usage

FDA Label (PDF)

LANREOTIDE ACETATE is indicated for the treatment of Acromegaly; Gastroenteropancreatic Neuroendocrine Tumors; Carcinoid Syndrome.

Looking for the branded version?

SOMATULINE DEPOT

Full clinical data, patents, trials, and competitive landscape for lanreotide acetate.

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.