| Bristol-Myers Squibb | A Study to Evaluate Mezigdomide in Combination With Carfilzomib and Dexamethasone (MeziKD) Versus Carfilzomib and Dexamethasone (Kd) in Participants With Relapsed or Refractory Multiple Myeloma (SUCCESSOR-2) Asset: Mezigdomide | Relapsed or Refractory Multiple Myeloma | Active Not Recruiting | Q3 2026 2026-07-18 (est.) | Estimated · fresh
Updated 4mo ago
| NCT05552976 |
| AstraZeneca | D9319C00001- 1L OC Mono Global RCT | Ovarian Cancer | Active Not Recruiting | Q3 2026 2026-07-27 (est.) | Estimated · fresh
Updated 5mo ago
| NCT04884360 |
| Jiangsu HengRui Medicine Co., Ltd. | A Study of TACE Combined With Camrelizumab Plus Rivoceranib (Apatinib) in Patients With Incurable Hepatocellular Carcinoma Asset: TACE+Camrelizumab+Apatinib mesylate | Hepatocellular Carcinoma | Active Not Recruiting | Q3 2026 2026-07-30 (est.) | Estimated · aging
Updated 7mo ago
| NCT05320692 |
| CSPC Megalith Biopharmaceutical Co… | Phase III Trial of SYS6010 Versus Platinum-based Chemotherapy for EGFR-mutated NSCLC(SYNSTAR01) Asset: SYS6010 | EGFR-mutated Locally Advanced or Metastatic NSCLC | Recruiting | Q3 2026 2026-07-30 (est.) | Estimated · aging
Updated 8mo ago
| NCT06927986 |
| Shenyang Sunshine Pharmaceutical C… | SSGJ-707 in Advanced Non-Small Cell Lung Cancer Asset: SSGJ-707 | Advanced Non-Small Cell Lung Cancer | Recruiting | Q3 2026 2026-07-30 (est.) | Estimated · stale
Updated 13mo ago
| NCT06980272 |
| Sichuan Kelun-Biotech Biopharmaceu… | A Study of SKB264 Versus Investigator's Choice Chemotherapy in Patients With Unresectable Recurrent or Metastatic Triple-Negative Breast Cancer Asset: SKB264 | Triple Negative Breast Cancer | Recruiting | Q3 2026 2026-07 (est.) | Estimated · fresh
Updated 6mo ago
| NCT06279364 |
| Merck Sharp & Dohme LLC | Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Bacillus Calmette-Guerin (BCG) in High-Risk Non-Muscle Invasive Bladder Cancer (HR NMIBC) (MK-3475-676/KEYNOTE-676) | High-risk Non-muscle Invasive Bladder Cancer | Active Not Recruiting | Q3 2026 2026-07-31 (est.) | Estimated · aging
Updated 7mo ago
| NCT03711032 |
| Jazz Pharmaceuticals | A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal Cancers | Gastric Neoplasms +2 | Active Not Recruiting | Q3 2026 2026-07-31 (est.) | Estimated · fresh
Updated 3mo ago
| NCT05152147 |
| Jiangsu HengRui Medicine Co., Ltd. | A Study to Evaluate Camrelizumab Plus Rivoceranib (Apatinib) as Adjuvant Therapy in Patients With Hepatocellular Carcinoma (HCC) at High Risk of Recurrence After Curative Resection or Ablation Asset: Camrelizumab | Hepatocellular Carcinoma (HCC) | Active Not Recruiting | Q3 2026 2026-07-31 (est.) | Estimated · aging
Updated 7mo ago
| NCT04639180 |
| Camurus AB | A Trial to Assess Efficacy and Safety of Octreotide Subcutaneous Depot in Patients With GEP-NET Asset: CAM2029 | Gastro-enteropancreatic Neuroendocrine Tumor | Active Not Recruiting | Q3 2026 2026-07 (est.) | Estimated · aging
Updated 8mo ago
| NCT05050942 |
| HUYABIO International, LLC. | Study Comparing Investigational Drug HBI-8000 + Nivolumab vs. Placebo + Nivolumab in Patients With Advanced Melanoma Asset: HBI-8000 in combination with nivolumab | Unresectable or Metastatic Melanoma +1 | Active Not Recruiting | Q3 2026 2026-07 (est.) | Estimated · aging
Updated 10mo ago
| NCT04674683 |
| Shanghai Hengrui Pharmaceutical Co… | A Phase III Study of SHR-A2102 Versus Investigator-selected Therapy in Advanced Urothelial Carcinoma Asset: SHR-A2102 for Injection | Advanced Urothelial Carcinoma | Recruiting | Q3 2026 2026-07 (est.) | Estimated · aging
Updated 12mo ago
| NCT06738251 |
| Sichuan Baili Pharmaceutical Co., … | A Clinical Study of SI-B001 Combined With Docetaxel in the Treatment of Non-small Cell Lung Adenocarcinoma and Lung Squamous Cell Carcinoma Asset: SI-B001 | Non-small Cell Lung Adenocarcinoma +1 | Active Not Recruiting | Q3 2026 2026-07 (est.) | Estimated · stale
Updated 13mo ago
| NCT05943795 |
| InnoPharmax Inc. | Study of Combination Therapy of D07001-Softgel Capsules and Xeloda/TS-1 in Subjects With Advanced Biliary Tract Cancer Asset: D07001-softgel capsules + Xeloda (or TS-1) | Biliary Tract Cancer | Recruiting | Q3 2026 2026-07 (est.) | Estimated · stale
Updated 15mo ago
| NCT05065957 |
| SUNHO(China)BioPharmaceutical CO.,… | To Evaluate IAH0968 in Combination With CAPEOX in HER2-positive Gastric Cancer Asset: IAH0968 | Stomach Neoplasms +1 | Recruiting | Q3 2026 2026-07 (est.) | Estimated · stale
Updated 18mo ago
| NCT06504732 |
| Daiichi Sankyo | A Study to Provide Continued Access to and Assess Long-Term Safety of the Study Drug(s) Asset: T-DXd | Advanced Cancer +1 | Recruiting | Q3 2026 2026-08-03 (est.) | Estimated · aging
Updated 9mo ago
| NCT06174987 |
| Shanghai Fudan-Zhangjiang Bio-Phar… | FDA018-ADC vs Investigator's Choice Chemotherapy to Treat Locally Advanced, Recurrent or Metastatic Triple-negative Breast Cancer Asset: FDA018-ADC | Triple Negative Breast Cancer | Active Not Recruiting | Q3 2026 2026-08-18 (est.) | Estimated · fresh
Updated 6mo ago
| NCT06519370 |
| Merck Sharp & Dohme LLC | Study of Pembrolizumab/Vibostolimab (MK-7684A) in Combination With Concurrent Chemoradiotherapy Followed by Pembrolizumab/Vibostolimab Versus Concurrent Chemoradiotherapy Followed by Durvalumab in Participants With Stage III Non-small Cell Lung Cancer (MK-7684A-006) | Carcinoma, Non-Small-Cell Lung | Active Not Recruiting | Q3 2026 2026-08-19 (est.) | Estimated · aging
Updated 12mo ago
| NCT05298423 |
| EMD Serono Research & Development … | Avelumab Program Rollover Study | Solid Tumors | Active Not Recruiting | Q3 2026 2026-08-21 (est.) | Estimated · fresh
Updated 4mo ago
| NCT03815643 |
| AstraZeneca | A Comparative Study of AZD9833 Plus Palbociclib Versus Anastrozole Plus Palbociclib in Patients With ER-Positive HER2 Negative Breast Cancer Who Have Not Received Any Systemic Treatment for Advanced Disease Asset: AZD9833 | ER-Positive HER2-Negative Breast Cancer | Active Not Recruiting | Q3 2026 2026-08-24 (est.) | Estimated · aging
Updated 9mo ago
| NCT04711252 |
| Novartis Pharmaceuticals | Study of JDQ443 in Comparison With Docetaxel in Participants With Locally Advanced or Metastatic KRAS G12C Mutant Non-small Cell Lung Cancer Asset: JDQ443 | Non-Small Cell Lung Cancer | Active Not Recruiting | Q3 2026 2026-08-25 (est.) | Estimated · fresh
Updated 3mo ago
| NCT05132075 |
| Panbela Therapeutics, Inc. | Study of Nab-Paclitaxel and Gemcitabine With or Without SBP-101 in Pancreatic Cancer Asset: SBP-101 | Pancreatic Cancer Metastatic +2 | Recruiting | Q3 2026 2026-08-29 (est.) | Estimated · stale
Updated 20mo ago
| NCT05254171 |
| Pfizer | MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide) | Multiple Myeloma | Recruiting | Q3 2026 2026-08-30 (est.) | Estimated · fresh
Updated 3mo ago
| NCT06152575 |
| Hutchison Medipharma Limited | Clinical Study on Savolitinib + Osimertinib in Treatment of EGFRm+/MET+ Locally Advanced or Metastatic NSCLC Asset: Savolitinib | Non-small Cell Lung Cancer | Active Not Recruiting | Q3 2026 2026-08-30 (est.) | Estimated · aging
Updated 11mo ago
| NCT05009836 |
| Daiichi Sankyo | Trastuzumab Deruxtecan for Subjects With HER2-Positive Gastric Cancer or Gastro-Esophageal Junction Adenocarcinoma After Progression on or After a Trastuzumab-Containing Regimen (DESTINY-Gastric04) | Gastric Cancer, Adenocarcinoma +1 | Active Not Recruiting | Q3 2026 2026-08-31 (est.) | Estimated · fresh
Updated 6mo ago
| NCT04704934 |
| Karyopharm Therapeutics Inc | Selinexor in Maintenance Therapy After Systemic Therapy for Participants With p53 Wild-Type, Advanced or Recurrent Endometrial Carcinoma | Endometrial Cancer | Active Not Recruiting | Q3 2026 2026-08 (est.) | Estimated · fresh
Updated 3mo ago
| NCT05611931 |
| Hansoh BioMedical R&D Company | Study of HS-20093 Versus Gemcitabine in Combination With Docetaxel in Treatment of Osteosarcoma After Previous Second-line Treatment Failure Asset: HS-20093 | Osteosarcoma | Active Not Recruiting | Q3 2026 2026-08-31 (est.) | Estimated · fresh
Updated 3mo ago
| NCT06935409 |
| AbbVie | A Study Designed to Evaluate the Safety and Efficacy of Venetoclax Plus Dexamethasone (VenDex) Compared With Pomalidomide Plus Dexamethasone (PomDex) in Participants With t(11;14)-Positive Relapsed or Refractory Multiple Myeloma. | Multiple Myeloma | Active Not Recruiting | Q3 2026 2026-08 (est.) | Estimated · stale
Updated 13mo ago
| NCT03539744 |
| Sunshine Lake Pharma Co., Ltd. | Study of Larotinib in Unresectable Advanced or Recurrent Esophageal Cancer Asset: Lerotinib | Esophageal Cancer | Recruiting | Q3 2026 2026-08 (est.) | Estimated · stale
Updated 14mo ago
| NCT04415853 |
| Yantai LNC Biotechnology Singapore… | Clinical Study of 18F-Alfatide Injection PET/CT Asset: 18F-Alfatide Injection | Non-Small Cell Lung Cancer NSCLC | Not Yet Recruiting | Q3 2026 2026-08 (est.) | Estimated · stale
Updated 26mo ago
| NCT06416852 |
| Incyte Corporation | Tafasitamab + Lenalidomide + R-CHOP Versus R-CHOP in Newly Diagnosed High-intermediate and High Risk DLBCL Patients | Diffuse Large B-cell Lymphoma | Active Not Recruiting | Q3 2026 2026-09-01 (est.) | Estimated · fresh
Updated 4mo ago
| NCT04824092 |
| Boehringer Ingelheim | Beamion LUNG-2: A Study to Test Whether Zongertinib (BI 1810631) Helps People With Advanced Non-small Cell Lung Cancer With HER2 Mutations Compared With Standard Treatment | Lung Cancer, Non-squamous, Non-small Cell | Active Not Recruiting | Q3 2026 2026-09-02 (est.) | Estimated · fresh
Updated 3mo ago
| NCT06151574 |
| Merck Sharp & Dohme LLC | Study of Pembrolizumab (MK-3475) in Combination With Adjuvant Chemotherapy With or Without Radiotherapy in Participants With Newly Diagnosed Endometrial Cancer After Surgery With Curative Intent (MK-3475-B21 / KEYNOTE-B21 / ENGOT-en11 / GOG-3053) | Endometrial Neoplasms | Active Not Recruiting | Q3 2026 2026-09-15 (est.) | Estimated · stale
Updated 13mo ago
| NCT04634877 |
| Han Xu, M.D., Ph.D., FAPCR, Sponso… | Pharmacogenomics ANDA SNP Clinical Study - Topotecan and Single Nucleotide Polymorphisms | SCLC | Active Not Recruiting | Q3 2026 2026-09-18 (est.) | Estimated · aging
Updated 10mo ago
| NCT07145333 |
| Clarity Pharmaceuticals Ltd | Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy Asset: 64Cu-SAR-bisPSMA | Prostate Cancer +1 | Recruiting | Q3 2026 2026-09 (est.) | Estimated · fresh
Updated 3mo ago
| NCT06056830 |
| Pfizer | Continued Access Study for Participants Deriving Benefit in Pfizer-Sponsored Avelumab Parent Studies That Are Closing | Advanced Malignancies +4 | Active Not Recruiting | Q3 2026 2026-09-30 (est.) | Estimated · fresh
Updated 3mo ago
| NCT05059522 |
| Curium US LLC | Copper Cu 64 PSMA I&T PET Imaging in Men With Newly Diagnosed Prostate Cancer | Prostate Cancer +1 | Recruiting | Q3 2026 2026-09 (est.) | Estimated · fresh
Updated 3mo ago
| NCT06235151 |
| AstraZeneca | A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib Compared With Platinum Based Doublet Chemotherapy in Participants With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer Asset: Dato-DXd | Metastatic Non-small Cell Lung Cancer | Recruiting | Q3 2026 2026-09-30 (est.) | Estimated · fresh
Updated 5mo ago
| NCT06417814 |
| Beijing Pearl Biotechnology Limite… | A Confirmatory Clinical Study in NSCLC Patients With MET Exon 14 Mutation (KUNPENG-2) Asset: PLB1001 | Non-small Cell Lung Cancer | Recruiting | Q3 2026 2026-09-30 (est.) | Estimated · stale
Updated 13mo ago
| NCT05989542 |
| Innovent Biologics (Suzhou) Co. Ltd. | Neoadjuvant and Adjuvant Therapy Studies of Sindilizumab in Resectable Lung Cancer | Non-Small Cell Lung Cancer | Active Not Recruiting | Q3 2026 2026-09-30 (est.) | Estimated · stale
Updated 13mo ago
| NCT05116462 |
| Mabwell (Shanghai) Bioscience Co.,… | A Study to Evaluate 9MW2821 Versus Chemotherapy in Subjects With Previously Treated Locally Advanced or Metastatic Urothelial Cancer Asset: 9MW2821 | Advanced Urothelial Carcinoma | Recruiting | Q3 2026 2026-09 (est.) | Estimated · stale
Updated 15mo ago
| NCT06196736 |
| Allist Pharmaceuticals, Inc. | JAB-21822 Combined With JAB-3312 Compared SOC in the First Line for Treatment of Advanced Non-small Cell Lung Cancer With KRAS p.G12C Mutation Asset: JAB-21822 | Advanced Non-squamous Non-small-cell Lung Cancer +1 | Recruiting | Q3 2026 2026-09-30 (est.) | Estimated · stale
Updated 15mo ago
| NCT06416410 |
| Bio-Thera Solutions | BAT1308 Combined with Platinum-Based Chemotherapy± Bevacizumab for PDL1-Positive (CPS ≥1) Cervical Cancer Asset: Recombinant humanized anti-PD-1 monoclonal antibody injection | Cervical Cancer | Recruiting | Q3 2026 2026-09 (est.) | Estimated · stale
Updated 17mo ago
| NCT06123884 |
| Shanghai JMT-Bio Inc. | A Clinical Study of JMT101 in Combination With Osimertinib Versus Osimertinib Alone as First-Line Treatment for Patients With Locally Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC) Harboring Epidermal Growth Factor Receptor (EGFR) Sensitive Mutations Asset: JMT101 | Locally Advanced or Metastatic Non-squamous NSCLC +2 | Recruiting | Q3 2026 2026-09-30 (est.) | Estimated · stale
Updated 19mo ago
| NCT06735391 |
| Hansoh BioMedical R&D Company | ARTEMIS-008:HS-20093 Compared With Topotecan in Subjects With Relapsed Small Cell Lung Cancer Asset: HS-20093 | Small Cell Lung Cancer | Recruiting | Q3 2026 2026-09-30 (est.) | Estimated · stale
Updated 21mo ago
| NCT06498479 |
| Chia Tai Tianqing Pharmaceutical G… | A Clinical Study of TQB2450 Combined With Anlotinib in Limited-Stage Small Cell Lung Cancer Patients Asset: TQB2450+Anlotinib | Small Cell Lung Cancer Limited Stage | Not Yet Recruiting | Q3 2026 2026-09 (est.) | Estimated · stale
Updated 25mo ago
| NCT06469879 |
| Janssen Research & Development, LLC | A Study of an Intermittent ADT Approach With Apalutamide Monotherapy in Participants With mCSPC | Metastatic Castrate-sensitive Prostate Cancer | Active Not Recruiting | Q4 2026 2026-10-12 (est.) | Estimated · fresh
Updated 4mo ago
| NCT05884398 |
| Shanghai JMT-Bio Inc. | JSKN003 Versus Trastuzumab Emtansine (T-DM1) for HER2-Positive, Advanced Breast Cancer Asset: JSKN003 | Unrespectable Locally Advanced and or Metastatic HER2 Positive Breast Cancer Participants | Recruiting | Q4 2026 2026-10-13 (est.) | Estimated · stale
Updated 16mo ago
| NCT06846437 |
| Merck Sharp & Dohme LLC | A Study of Belzutifan (MK-6482) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Clear Cell Renal Cell Carcinoma Post Nephrectomy (MK-6482-022) | Carcinoma, Renal Cell | Active Not Recruiting | Q4 2026 2026-10-28 (est.) | Estimated · aging
Updated 11mo ago
| NCT05239728 |
| Akeso | A Study of AK104 in Subjects With Unresectable Locally Advanced NSCLC Asset: Cadonilimab (AK104) | NSCLC (Non-small Cell Lung Cancer) | Recruiting | Q4 2026 2026-10-28 (est.) | Estimated · stale
Updated 16mo ago
| NCT06617416 |
| Merck Sharp & Dohme LLC | A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, Versus Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012) | Carcinoma, Renal Cell | Active Not Recruiting | Q4 2026 2026-10-29 (est.) | Estimated · stale
Updated 20mo ago
| NCT04736706 |
| Laekna Limited | Study to Evaluate Efficacy & Safety of Afuresertib Plus Fulvestrant in Patients With Locally Advanced or Metastatic HR+/HER2- Breast Cancer Asset: Afuresertib | Breast Cancer | Active Not Recruiting | Q4 2026 2026-10-30 (est.) | Estimated · fresh
Updated 4mo ago
| NCT04851613 |
| UroGen Pharma Ltd. | A Phase 3 Single-arm Study of UGN-104 for the Treatment of Low-grade Upper Tract Urothelial Cancer Asset: UGN-104 | Upper Urinary Tract Urothelial Carcinoma +1 | Recruiting | Q4 2026 2026-10 (est.) | Estimated · fresh
Updated 6mo ago
| NCT06774131 |
| Privo Technologies | A Study Evaluating the Safety and Efficacy of PRV111, PRV211, and PRV131 in Subjects With Oral and Lung Cancers Asset: PRV211 (Intraoperative Cisplatin System) | Oral Squamous Cell Carcinoma | Recruiting | Q4 2026 2026-10 (est.) | Estimated · fresh
Updated 3mo ago
| NCT05893888 |
| Takeda | TAK-788 as First-Line Treatment Versus Platinum-Based Chemotherapy for Non-Small Cell Lung Cancer (NSCLC) With EGFR Exon 20 Insertion Mutations Asset: TAK-788 | Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC) | Active Not Recruiting | Q4 2026 2026-10-31 (est.) | Estimated · fresh
Updated 4mo ago
| NCT04129502 |
| AstraZeneca | Capivasertib+Fulvestrant asTreatment for Locally Advanced(Inoperable) or Metastatic HR+/HER2- Breast Cancer in Chinese Patients | Breast Cancer | Active Not Recruiting | Q4 2026 2026-10-31 (est.) | Estimated · fresh
Updated 4mo ago
| NCT06635447 |
| Hoffmann-La Roche | A Study to Evaluate the Efficacy and Safety of Multiple Targeted Therapies as Treatments for Participants With Non-Small Cell Lung Cancer (NSCLC) Asset: Alectinib | Non-Small Cell Lung Cancer | Active Not Recruiting | Q4 2026 2026-10-31 (est.) | Estimated · fresh
Updated 4mo ago
| NCT03178552 |
| Loxo Oncology, Inc. | A Trial of Pirtobrutinib (LOXO-305) Plus Venetoclax and Rituximab (PVR) Versus Venetoclax and Rituximab (VR) in Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) | Chronic Lymphocytic Leukemia +1 | Active Not Recruiting | Q4 2026 2026-10 (est.) | Estimated · fresh
Updated 6mo ago
| NCT04965493 |
| Akeso | AK112 Combined With Chemotherapy Versus Durvalumab Combined With Chemotherapy in Advanced Biliary Tract Cancer Asset: AK112, Gemcitabine, Cisplatin | Biliary Tract Cancer | Active Not Recruiting | Q4 2026 2026-10 (est.) | Estimated · fresh
Updated 6mo ago
| NCT06591520 |
| CSPC ZhongQi Pharmaceutical Techno… | Sirolimus for Injection (Albumin-bound) Combined With Fulvestrant for HR+/HER2- Advanced/Metastatic Breast Cancer Patients Previously Treated With CDK4/6 Inhibitors | HR+/HER2- Advanced/Metastatic Breast Cancer | Not Yet Recruiting | Q4 2026 2026-10 (est.) | Estimated · stale
Updated 15mo ago
| NCT06929325 |
| Immutep S.A.S. | Study in Metastatic Breast Cancer Patients Receiving Eftilagimod Alpha or Placebo in Combination with Paclitaxel Chemotherapy Asset: eftilagimod alpha | Breast Carcinoma | Active Not Recruiting | Q4 2026 2026-10-31 (est.) | Estimated · stale
Updated 19mo ago
| NCT05747794 |
| Jiangsu HengRui Medicine Co., Ltd. | Phase III Study :SHR6390/Placebo Combined With Endocrine Therapy for the Adjuvant Treatment of Hormone Receptor Positive,Human Epidermal Receptor 2 Negative Asset: SHR6390 | Hormone Receptor Positive,Human Epidermal Receptor 2 Negative, Node-positive, High Risk, Early Stage,Female Breast Cancer | Active Not Recruiting | Q4 2026 2026-10-31 (est.) | Estimated · stale
Updated 24mo ago
| NCT04842617 |
| Chia Tai Tianqing Pharmaceutical G… | D-1553 Tablet Versus Docetaxel Injection for KRAS G12C Mutation-positive Locally Advanced or Metastatic Non-small Cell Lung Cancer After Prior Standard Therapy Failure Asset: D-1553 Tablet | Non Small Cell Lung Cancer | Recruiting | Q4 2026 2026-10 (est.) | Estimated · stale
Updated 27mo ago
| NCT06300177 |
| Han Xu, M.D., Ph.D., FAPCR, Sponso… | Pharmacogenomics IND SNP Clinical Trial - Alectinib and Single Nucleotide Polymorphisms Asset: Alectinib - Usual | ALK-Positive Non-Small Cell Lung Cancer (NSCLC) | Active Not Recruiting | Q4 2026 2026-11-18 (est.) | Estimated · fresh
Updated 3mo ago
| NCT05987956 |
| Han Xu, M.D., Ph.D., FAPCR, Sponso… | Pharmacogenomics ANDA SNP Clinical Study - Etoposide and Single Nucleotide Polymorphisms | Small Cell Lung Cancer | Active Not Recruiting | Q4 2026 2026-11-18 (est.) | Estimated · aging
Updated 12mo ago
| NCT01064466 |
| Tesaro, Inc. | A Study to Evaluate Dostarlimab Plus Carboplatin-paclitaxel Versus Placebo Plus Carboplatin-paclitaxel in Participants With Recurrent or Primary Advanced Endometrial Cancer | Neoplasms | Active Not Recruiting | Q4 2026 2026-11-26 (est.) | Estimated · aging
Updated 10mo ago
| NCT03981796 |
| Sichuan Kelun-Biotech Biopharmaceu… | A Study of SKB264 in Combination With Pembrolizumab Versus Pembrolizumab in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Asset: SKB264 | Non-Small Cell Lung Cancer | Active Not Recruiting | Q4 2026 2026-11 (est.) | Estimated · fresh
Updated 4mo ago
| NCT06448312 |
| InventisBio Co., Ltd | A Study to Evaluate D-0502 in Subjects With ER+ Her2- Locally Advanced or Metastatic Breast Cancer Asset: D-0502 | Breast Cancer | Recruiting | Q4 2026 2026-11-30 (est.) | Estimated · fresh
Updated 4mo ago
| NCT06954961 |
| Qilu Pharmaceutical Co., Ltd. | Efficacy and Safety Study of QLG1080 in Patients With Hormone-sensitive Advanced Prostate Cancer Asset: QLG1080 | Prostate Cancer | Not Yet Recruiting | Q4 2026 2026-11 (est.) | Estimated · stale
Updated 17mo ago
| NCT06837896 |
| CAS Lamvac (Guangzhou) Biomedical … | Plasmodium Immunotherapy for Advanced Ovarian Cancer Asset: Plasmodium immunotherapy | Advanced Ovarian Cancer | Not Yet Recruiting | Q4 2026 2026-11-30 (est.) | Estimated · stale
Updated 24mo ago
| NCT05924776 |
| Janssen Research & Development, LLC | A Study of Apalutamide in Participants With High-Risk, Localized or Locally Advanced Prostate Cancer Who Are Candidates for Radical Prostatectomy | Prostatic Neoplasms | Active Not Recruiting | Q4 2026 2026-12-01 (est.) | Estimated · fresh
Updated 3mo ago
| NCT03767244 |
| Shanghai Pharmaceuticals Holding C… | Safety and Efficacy of SPH4336 in Combination With Endocrine Therapy in the Treatment of Locally Advanced or Metastatic Breast Cancer Asset: SPH4336 Tablets | Locally Advanced or Metastatic Breast Cancer | Recruiting | Q4 2026 2026-12-01 (est.) | Estimated · fresh
Updated 6mo ago
| NCT05860465 |
| Pfizer | A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer. Asset: PF-06821497 | Metastatic Castration-Resistant Prostate Cancer | Recruiting | Q4 2026 2026-12-02 (est.) | Estimated · fresh
Updated 3mo ago
| NCT06629779 |
| CSPC Megalith Biopharmaceutical Co… | A Phase Ⅲ Clinical Study of SYS6010 in Combination With Osimertinib in Patients With Locally Advanced or Metastatic NSCLC Asset: SYS6010 | NSCLC | Not Yet Recruiting | Q4 2026 2026-12-12 (est.) | Estimated · fresh
Updated 5mo ago
| NCT07376382 |
| Amgen | Pharmacokinetic Similarity Between ABP 234 and Keytruda® (Pembrolizumab) Asset: ABP 234 | Early-stage Non-squamous Non-small Cell Lung Cancer (NSCLC) | Active Not Recruiting | Q4 2026 2026-12-14 (est.) | Estimated · fresh
Updated 4mo ago
| NCT06430866 |
| Shanghai JMT-Bio Inc. | A Phase III Study of KN026 in Combination With HB1801 ± Carboplatin as Neoadjuvant Treatment for Early or Locally Advanced HER2-Positive Breast Cancer Asset: KN026 | Early or Locally Advanced HER2-positive Breast Cancer | Active Not Recruiting | Q4 2026 2026-12-16 (est.) | Estimated · stale
Updated 15mo ago
| NCT06747338 |
| Han Xu, M.D., Ph.D., FAPCR, Sponso… | Bioequivalence ANDA SNP Clinical Study - Raloxifene and Single Nucleotide Polymorphisms Asset: Raloxifene - Usual | Breast Cancer | Active Not Recruiting | Q4 2026 2026-12-18 (est.) | Estimated · fresh
Updated 3mo ago
| NCT06062810 |
| Hoffmann-La Roche | A Study Evaluating the Efficacy and Safety of Multiple Therapies in Cohorts of Participants With Locally Advanced, Unresectable, Stage III Non-Small Cell Lung Cancer (NSCLC) Asset: Alectinib | Non-Small Cell Lung Cancer | Active Not Recruiting | Q4 2026 2026-12-20 (est.) | Estimated · fresh
Updated 4mo ago
| NCT05170204 |
| Shanghai Kechow Pharma, Inc. | Efficacy and Safety of Tunlametinib Plus Vemurafenib in Patients With BRAF V600E-mutant Metastatic Colorectal Cancer Asset: Tunlametinib plus Vemurafenib | Colorectal Cancer Metastatic | Recruiting | Q4 2026 2026-12-24 (est.) | Estimated · aging
Updated 10mo ago
| NCT06008119 |
| Jiangsu Healthy Life Innovation Me… | Clinical Study of Tumor Treating Fields Combined with Gemcitabine and Albumin-bound Paclitaxel in the First-line Treatment of Locally Advanced Pancreatic Cancer | Locally Advanced Pancreatic Cancer | Recruiting | Q4 2026 2026-12-25 (est.) | Estimated · stale
Updated 16mo ago
| NCT05653453 |
| CanariaBio Inc. | Oregovomab Plus Chemo in Newly Diagnosed Patients With Advanced Epithelial Ovarian Cancer Following Optimal Debulking Surgery Asset: Oregovomab | Carcinoma, Ovarian Epithelial +9 | Active Not Recruiting | Q4 2026 2026-12-26 (est.) | Estimated · fresh
Updated 4mo ago
| NCT04498117 |
| Janssen Research & Development, LLC | A Study of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-invasive Bladder Cancer (MIBC) of the Bladder Asset: Cetrelimab | Urinary Bladder Neoplasms | Active Not Recruiting | Q4 2026 2026-12-30 (est.) | Estimated · fresh
Updated 3mo ago
| NCT04658862 |
| Pfizer | Vepdegestrant (ARV-471/PF-07850327) + Palbociclib vs Letrozole + Palbociclib in ER(+)/HER2(-) Advanced Breast Cancer | Breast Cancer | Active Not Recruiting | Q4 2026 2026-12-30 (est.) | Estimated · fresh
Updated 5mo ago
| NCT05909397 |
| AskGene Pharma, Inc. | ASKB589 in Combination With CAPOX and PD-1 Inhibitor in Patients With Advanced or Metastatic GC/GEJ Adenocarcinoma Asset: ASKB589 | Gastroesophageal Junction Adenocarcinoma +1 | Active Not Recruiting | Q4 2026 2026-12-30 (est.) | Estimated · fresh
Updated 6mo ago
| NCT06206733 |
| Xynomic Pharmaceuticals, Inc. | A Study of Pazopanib With or Without Abexinostat in Patients With Locally Advanced or Metastatic Renal Cell Carcinoma (RENAVIV) Asset: Pazopanib | Renal Cell Carcinoma | Recruiting | Q4 2026 2026-12-30 (est.) | Estimated · stale
Updated 15mo ago
| NCT03592472 |
| Jiangsu vcare pharmaceutical techn… | Phase III Clinical Study of VC004 in Patients With Localized Advanced/ Metastatic Solid Tumors Asset: VC004 Capsules | Locally Advanced Solid Tumor | Recruiting | Q4 2026 2026-12-30 (est.) | Estimated · stale
Updated 16mo ago
| NCT06658353 |
| Jiangsu Alphamab Biopharmaceutical… | JSKN003 in Platinum-Resistant, Relapsed Epithelial Ovarian Cancer Asset: JSKN003 | Ovarian Cancer +2 | Not Yet Recruiting | Q4 2026 2026-12-30 (est.) | Estimated · stale
Updated 19mo ago
| NCT06751485 |
| Beijing Konruns Pharmaceutical Co.… | A Study of KC1036 Versus Investigator's Choice of Chemotherapy in Patients With Advanced Esophageal Cancer Asset: KC1036 | Esophageal Squamous Cell Carcinoma | Recruiting | Q4 2026 2026-12-30 (est.) | Estimated · stale
Updated 28mo ago
| NCT06194734 |
| Hoffmann-La Roche | A Safety and Efficacy Extension Study of Pertuzumab in Patients With Solid Tumors Previously Enrolled in a Hoffmann-La Roche-Sponsored Pertuzumab Clinical Trial | Solid Tumors | Active Not Recruiting | Q4 2026 2026-12-31 (est.) | Estimated · fresh
Updated 5mo ago
| NCT02320435 |
| Janssen Research & Development, LLC | A Long-term Extension Study of PCI-32765 (Ibrutinib) | Chronic Lymphocytic Leukemia +6 | Recruiting | Q4 2026 2026-12-31 (est.) | Estimated · fresh
Updated 3mo ago
| NCT01804686 |
| Hoffmann-La Roche | A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer | Metastatic Breast Cancer | Recruiting | Q4 2026 2026-12-31 (est.) | Estimated · fresh
Updated 4mo ago
| NCT05894239 |
| Swedish Orphan Biovitrum | A Phase 3 Study of Pacritinib in Patients With Primary Myelofibrosis, Post Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis Asset: Pacritinib | Primary Myelofibrosis +2 | Active Not Recruiting | Q4 2026 2026-12-31 (est.) | Estimated · fresh
Updated 5mo ago
| NCT03165734 |
| AstraZeneca | Roll Over StudY for Patients Who Have Completed a Previous Oncology Study With Durvalumab | Cancer | Enrolling By Invitation | Q4 2026 2026-12-31 (est.) | Estimated · fresh
Updated 3mo ago
| NCT05303532 |
| Jiangsu HengRui Medicine Co., Ltd. | An Open-label Phase 3 Study of Lutetium (177Lu) Oxodotreotide Injection in Subjects With Advanced Gastrointestinal Pancreatic Neuroendocrine Tumors. Asset: Lutetium (177Lu) Oxodotreotide Injection;long-acting Octreotide | Advanced Gastroenteropancreatic Neuroendocrine Tumor | Recruiting | Q4 2026 2026-12 (est.) | Estimated · fresh
Updated 3mo ago
| NCT05884255 |
| Chia Tai Tianqing Pharmaceutical G… | Clinical Study on Adjuvant Therapy of TQB3616 Combined With Endocrine Therapy Compared With Placebo Combined With Endocrine Therapy in Patients With Breast Cancer Asset: TQB3616 capsules, Letrozole, Anastrozole, Tamoxifen | Breast Cancer | Active Not Recruiting | Q4 2026 2026-12 (est.) | Estimated · fresh
Updated 3mo ago
| NCT05780567 |
| Sichuan Baili Pharmaceutical Co., … | A Study Comparing BL-B01D1 With Docetaxel in Patients With Unresectable Locally Advanced or Metastatic EGFR Wild-type Non-small Cell Lung Cancer(PANKU-Lung02) Asset: BL-B01D1 | Non-small Cell Lung Cancer | Active Not Recruiting | Q4 2026 2026-12 (est.) | Estimated · fresh
Updated 3mo ago
| NCT06382129 |
| Sichuan Baili Pharmaceutical Co., … | A Study Comparing BL-B01D1 With Topotecan in Patients With Recurrent Small Cell Lung Cancer(PANKU-Lung03) Asset: BL-B01D1 | Small Cell Lung Cancer | Active Not Recruiting | Q4 2026 2026-12 (est.) | Estimated · fresh
Updated 3mo ago
| NCT06500026 |
| NaviFUS Corporation | A Prospective Pivotal Study to Evaluate the Efficacy and Safety of Avastin® Bevacizumab (BEV) With or Without Microbubble-mediated Focused Ultrasound (FUS-MB) Using NaviFUS System in Recurrent Glioblastoma Multiforme Patients | Glioblastoma Multiforme +7 | Recruiting | Q4 2026 2026-12-31 (est.) | Estimated · fresh
Updated 3mo ago
| NCT06496971 |
| Clarity Pharmaceuticals Ltd | 64Cu-SAR-bisPSMA Positron Emission Tomography: A Phase 3 Study of Participants With Biochemical Recurrence of Prostate Cancer Asset: 64Cu-SAR-bisPSMA | Prostate Cancer +5 | Active Not Recruiting | Q4 2026 2026-12-31 (est.) | Estimated · fresh
Updated 3mo ago
| NCT06970847 |
| RayzeBio, Inc. | Study of RYZ101 Compared With SOC in Pts w Inoperable SSTR+ Well-differentiated GEP-NET That Has Progressed Following 177Lu-SSA Therapy Asset: RYZ101 | GEP-NET +6 | Recruiting | Q4 2026 2026-12 (est.) | Estimated · fresh
Updated 4mo ago
| NCT05477576 |
| Vergent Bioscience, Inc. | Evaluation of the Safety and Efficacy of Abenacianine (VGT-309) to Identify Cancer in Subjects Undergoing Surgery for Cancer in the Lung Asset: Abenacianine | Lung Cancer +1 | Recruiting | Q4 2026 2026-12 (est.) | Estimated · fresh
Updated 4mo ago
| NCT07499674 |
| Greenwich LifeSciences, Inc. | Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects Asset: Placebo | Breast Cancer | Recruiting | Q4 2026 2026-12 (est.) | Estimated · fresh
Updated 4mo ago
| NCT05232916 |
| Suzhou Suncadia Biopharmaceuticals… | A Study of SHR-A2009 Versus Platinum-based Chemotherapy in EGFR-mutated, Advanced or Metastatic NSCLC Asset: SHR-A2009 monotherapy | Non-small Cell Lung Cancer | Active Not Recruiting | Q4 2026 2026-12 (est.) | Estimated · fresh
Updated 4mo ago
| NCT06671379 |
| Akeso | AK112 or Placebo Plus Nab-Paclitaxel as First-line Treatment in Inoperable Locally Advanced/ Metastatic Triple-negative Breast Cancer Asset: AK112 | Triple-Negative Breast Cancer (TNBC) | Recruiting | Q4 2026 2026-12 (est.) | Estimated · fresh
Updated 4mo ago
| NCT06767527 |
| Aldeyra Therapeutics, Inc. | A Clinical Trial Evaluating Patients With Primary Vitreoretinal Lymphoma Asset: ICM ADX-2191 injection | Primary Vitreoretinal Lymphoma | Recruiting | Q4 2026 2026-12 (est.) | Estimated · fresh
Updated 5mo ago
| NCT07402876 |
| Gilead Sciences | Asian Study of Sacituzumab Govitecan (IMMU-132) in HR+/HER2- Metastatic Breast Cancer (MBC) | Metastatic Breast Cancer | Active Not Recruiting | Q4 2026 2026-12 (est.) | Estimated · fresh
Updated 5mo ago
| NCT04639986 |
| Sichuan Kelun-Biotech Biopharmaceu… | A Study of SKB264 in Combination With Pembrolizumab Versus Chemotherapy in Combination With Pembrolizumab as First-Line Treatment for PD-L1 Negative Patients With Locally Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer Asset: SKB264 | Non-Small Cell Lung Cancer | Active Not Recruiting | Q4 2026 2026-12 (est.) | Estimated · fresh
Updated 5mo ago
| NCT06711900 |
| Shandong Suncadia Medicine Co., Ltd. | A Phase 3 Study of HRS-8080 Versus Treatment Chosen by Physicians in Locally Advanced and Metastatic Breast Cancer Asset: HRS-8080 Tablet | Locally Advanced Breast Cancer +1 | Recruiting | Q4 2026 2026-12 (est.) | Estimated · fresh
Updated 6mo ago
| NCT07024173 |
| Guangzhou Gloria Biosciences Co., … | Mobilization of Stem Cells With Motixafortide (BL-8040) in Combination With G-CSF in Multiple Myeloma Patients Asset: Motixafortide+G-CSF | Multiple Myeloma | Recruiting | Q4 2026 2026-12-31 (est.) | Estimated · aging
Updated 7mo ago
| NCT06514508 |
| Kartos Therapeutics, Inc. | Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib Asset: Navtemadlin | Myelofibrosis +4 | Recruiting | Q4 2026 2026-12-31 (est.) | Estimated · aging
Updated 10mo ago
| NCT06479135 |
| Qilu Pharmaceutical Co., Ltd. | Pharmacokinetic Study of QL2107 Versus Keytruda® for Adjuvant Therapy of Non-Small Cell Lung Cancer (NSCLC) Asset: QL2107 | Carcinoma, Non-Small-Cell Lung | Not Yet Recruiting | Q4 2026 2026-12-31 (est.) | Estimated · aging
Updated 10mo ago
| NCT07162883 |
| Jiangsu HengRui Medicine Co., Ltd. | A Trial of SHR-A1811versus Pyrotinib in Combination With Capecitabine in HER2-Positive, Unresectable and/or Metastatic Breast Cancer Subjects Previously Treated With Trastuzumab and Taxane Asset: SHR-A1811 | HER2-Positive, Unresectable and/or Metastatic Breast Cancer Subjects Previously Treated With Trastuzumab and Taxane | Active Not Recruiting | Q4 2026 2026-12-31 (est.) | Estimated · aging
Updated 11mo ago
| NCT05424835 |
| TVAX Biomedical | Study of Neoantigen-specific Adoptive T Cell Therapy for Newly Diagnosed MGMT Negative Glioblastoma Multiforme (GBM) Asset: TVI-Brain-1 | Glioblastoma Multiforme of Brain | Active Not Recruiting | Q4 2026 2026-12 (est.) | Estimated · stale
Updated 13mo ago
| NCT05685004 |
| Qilu Pharmaceutical Co., Ltd. | A Study to Evaluate Efficacy, and Safety of QL2107 Plus Chemo and Compare With Keytruda in Participants With IV nqNSCLC Asset: QL2107 | NSCLC | Recruiting | Q4 2026 2026-12 (est.) | Estimated · stale
Updated 13mo ago
| NCT06754644 |
| Changchun GeneScience Pharmaceutic… | Nano-crystalline Megestrol Acetate Combined With Standard Treatment Versus Standard Treatment for First-line Extensive-stage Small Cell Lung Cancer in the Cachexia Phase Asset: Nano-crystalline Megestrol Acetate Oral Suspension | Extensive-stage Small Cell Lung Cancer (ES-SCLC) +1 | Not Yet Recruiting | Q4 2026 2026-12-31 (est.) | Estimated · stale
Updated 14mo ago
| NCT06961201 |
| Chia Tai Tianqing Pharmaceutical G… | A Phase III Clinical Trial of AK105 Injection Combined With Anlotinib Hydrochloride Capsules Versus Sorafenib in Subjects With Advanced Hepatocellular Carcinoma (HCC) Asset: AK105 Injection | Advanced Hepatocellular Carcinoma (HCC) | Active Not Recruiting | Q4 2026 2026-12 (est.) | Estimated · stale
Updated 17mo ago
| NCT04344158 |
| Jiangsu HengRui Medicine Co., Ltd. | A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase III Study of Fuzuloparib Combined With Abiraterone Acetate and Prednisone (AA-P) Versus Placebo Combined With AA-P as First-Line Treatment in Patients With Metastatic Castration-Resistant Prostate Cancer Asset: Fuzuloparib , Abiraterone acetate and Prednisone | Metastatic Castration-Resistant Prostate Cancer (mCRPC) | Active Not Recruiting | Q4 2026 2026-12-31 (est.) | Estimated · stale
Updated 19mo ago
| NCT04691804 |
| Mabscale, LLC | A Safety and Efficacy Study of Bevacizumab, Paclitaxel, Carboplatin Compared to Avastin® in Non-Small Cell Lung Cancer | Non-Small Cell Lung Cancer | Recruiting | Q4 2026 2026-12 (est.) | Estimated · stale
Updated 23mo ago
| NCT05654454 |
| RemeGen Co., Ltd. | DV Combined With Cadonilimab in Subjects With HER2-expressing Gastric Cancer and Gastroesophageal Junction Adenocarcinoma After Progression on First-line Therapy Asset: Disitamab Vedotin Injection | Gastric Cancer +1 | Recruiting | Q4 2026 2026-12 (est.) | Estimated · stale
Updated 27mo ago
| NCT06221748 |
| RemeGen Co., Ltd. | A Study of RC48-ADC Combined With Toripalimab For First-line Treatment of Urothelial Carcinoma Asset: RC48-ADC | Urothelial Carcinoma +1 | Recruiting | Q4 2026 2026-12-31 (est.) | Estimated · stale
Updated 31mo ago
| NCT05302284 |
| GC Cell Corporation | Safety and Efficacy of Immuncell-LC With Gemcitabine in Resectable Pancreatic Cancer Asset: Immuncell-LC | Pancreatic Ductal Adenocarcinoma | Recruiting | Q4 2026 2026-12 (est.) | Estimated · stale
Updated 56mo ago
| NCT04969731 |
| Merck Sharp & Dohme LLC | A Study to Evaluate Sacituzumab Tirumotecan (MK-2870) in Advanced/Metastatic Gastroesophageal Adenocarcinoma (MK-2870-015) Asset: Sacituzumab tirumotecan | Gastroesophageal Cancer | Active Not Recruiting | Q1 2027 2027-01-04 (est.) | Estimated · fresh
Updated 5mo ago
| NCT06356311 |
| Celgene | A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM) Asset: mezigdomide | Relapsed or Refractory Multiple Myeloma | Recruiting | Q1 2027 2027-01-10 (est.) | Estimated · fresh
Updated 4mo ago
| NCT05519085 |
| FutureGen Biopharmaceutical (Beiji… | M108 Plus CAPOX Versus Placebo Plus CAPOX as First-line Treatment for Claudin (CLDN) 18.2-Positive, HER2-Negative, PD-L1 CPS<5, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma. Asset: M108 monoclonal antibody | Locally Advanced Unresectable or Metastatic Gastric Cancer +1 | Recruiting | Q1 2027 2027-01-11 (est.) | Estimated · stale
Updated 29mo ago
| NCT06177041 |
| Merck Sharp & Dohme LLC | Study of Pembrolizumab (MK-3475) Monotherapy Versus Sacituzumab Govitecan in Combination With Pembrolizumab for Participants With Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-3475-D46) | Carcinoma, Non-Small-Cell Lung | Active Not Recruiting | Q1 2027 2027-01-12 (est.) | Estimated · aging
Updated 7mo ago
| NCT05609968 |
| IDEAYA Biosciences | IDE196 (Darovasertib) in Combination With Crizotinib as First-line Therapy in Metastatic Uveal Melanoma Asset: IDE196 | Metastatic Uveal Melanoma | Active Not Recruiting | Q1 2027 2027-01-15 (est.) | Estimated · fresh
Updated 5mo ago
| NCT05987332 |
| Biotheus Inc. | PM8002 in Combination With Paclitaxel Compared With Chemotherapy as Second-line Treatment in Small Cell Lung Cancer Asset: PM8002 | SCLC | Active Not Recruiting | Q1 2027 2027-01-25 (est.) | Estimated · stale
Updated 19mo ago
| NCT06616532 |
| Novartis Pharmaceuticals | Study to Assess the Efficacy and Safety of Alpelisib Plus Fulvestrant in Participants With HR-positive (HR+), HER2-negative, Advanced Breast Cancer After Treatment With a CDK4/6 Inhibitor and an Aromatase Inhibitor. | Breast Cancer | Active Not Recruiting | Q1 2027 2027-01-28 (est.) | Estimated · fresh
Updated 3mo ago
| NCT05038735 |
| Shanghai Runshi Pharmaceutical Tec… | A Study of Simmitinib Versus Chemotherapy for Participants With Advanced Oesophageal Squamous Cell Carcinoma Asset: simmitinib | Advanced Oesophageal Squamous Cell Carcinoma | Not Yet Recruiting | Q1 2027 2027-01-30 (est.) | Estimated · stale
Updated 21mo ago
| NCT06656091 |
| Merck Sharp & Dohme LLC | Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Chemoradiotherapy (CRT) Versus CRT Alone in Muscle-invasive Bladder Cancer (MIBC) (MK-3475-992/KEYNOTE-992) | Urinary Bladder Neoplasms | Active Not Recruiting | Q1 2027 2027-01-31 (est.) | Estimated · stale
Updated 20mo ago
| NCT04241185 |
| Resilience | Randomized Controlled Trial of Remote Symptoms Monitoring With Resilience PRO Compared to Care As Usual Only | Cancer | Recruiting | Q1 2027 2027-01 (est.) | Estimated · fresh
Updated 3mo ago
| NCT06867705 |
| Chia Tai Tianqing Pharmaceutical G… | A Study of AL2846 Capsule Versus Placebo in the Treatment of Advanced Radioiodine-Refractory Differentiated Thyroid Carcinoma Asset: AL2846 Capsules | Thyroid Cancer | Recruiting | Q1 2027 2027-01 (est.) | Estimated · aging
Updated 7mo ago
| NCT06860971 |
| NX Development Corp | Gleolan for Visualization of Newly Diagnosed or Recurrent Ovarian Cancer (OVA-302) | Ovarian Cancer | Recruiting | Q1 2027 2027-01 (est.) | Estimated · aging
Updated 10mo ago
| NCT05804370 |
| Biocad | A Study of Neoadjuvant Therapy With BCD-217 (Nurulimab + Prolgolimab) in Patients With Resectable Stage III Skin Melanoma Asset: BCD-217 | Melanoma Stage III +1 | Active Not Recruiting | Q1 2027 2027-01 (est.) | Estimated · aging
Updated 12mo ago
| NCT05751928 |
| Loxo Oncology, Inc. | Study of BTK Inhibitor LOXO-305 Versus Approved BTK Inhibitor Drugs in Patients With Mantle Cell Lymphoma (MCL) | Lymphoma, Mantle-Cell | Active Not Recruiting | Q1 2027 2027-01 (est.) | Estimated · stale
Updated 14mo ago
| NCT04662255 |
| Acerta Pharma BV | Study of Acalabrutinib (ACP-196) in Combination With Venetoclax (ABT-199), With and Without Obinutuzumab (GA101) Versus Chemoimmunotherapy for Previously Untreated CLL | Chronic Lymphocytic Leukemia | Active Not Recruiting | Q1 2027 2027-01-31 (est.) | Estimated · stale
Updated 19mo ago
| NCT03836261 |
| Akeso | A Phase 3 Study of AK112 Plus AK117 Versus Pembrolizumab in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) Asset: AK117 in combination with AK112 | Head and Neck Squamous Cell Carcinoma | Recruiting | Q1 2027 2027-01 (est.) | Estimated · stale
Updated 20mo ago
| NCT06601335 |
| Chia Tai Tianqing Pharmaceutical G… | A Clinical Trial to Evaluate the Efficacy and Safety of TQB2102 for Injection Versus Investigator-Selected Chemotherapy in HER2 Low-Expressing Recurrent/Metastatic Breast Cancer Asset: TQB2102 for Injection | Breast Cancer | Not Yet Recruiting | Q1 2027 2027-01 (est.) | Estimated · stale
Updated 23mo ago
| NCT06561607 |
| Merck Sharp & Dohme LLC | Study of Pembrolizumab (MK-3475) Versus Placebo in Participants With Esophageal Carcinoma Who Are Receiving Chemotherapy and Radiation Therapy (MK-3475-975/KEYNOTE-975) | Esophageal Squamous Cell Carcinoma (ESCC) +2 | Active Not Recruiting | Q1 2027 2027-02-01 (est.) | Estimated · stale
Updated 20mo ago
| NCT04210115 |
| GlaxoSmithKline | A Study of Belrestotug Plus Dostarlimab Compared With Placebo Plus Pembrolizumab in Previously Untreated Participants With Programmed Death Ligand 1 (PD-L1) High Non-small-cell Lung Cancer (NSCLC) | Lung Cancer, Non-Small Cell | Active Not Recruiting | Q1 2027 2027-02-02 (est.) | Estimated · aging
Updated 10mo ago
| NCT06472076 |
| Epizyme, Inc. | A Study to Assess the Efficacy, Safety, Pharmacodynamics, and Pharmacokinetics of Tazemetostat in Combination With Lenalidomide Plus Rituximab Versus Placebo in Combination With Lenalidomide Plus Rituximab in Adult Patients at Least 18 Years of Age With Relapsed/Refractory Follicular Lymphoma. Asset: Tazemetostat | Relapsed/Refractory Follicular Lymphoma +2 | Active Not Recruiting | Q1 2027 2027-02-13 (est.) | Estimated · fresh
Updated 3mo ago
| NCT04224493 |
| Acerta Pharma BV | A Study of BR Alone Versus in Combination With Acalabrutinib in Subjects With Previously Untreated MCL | Lymphoma, Mantle Cell | Active Not Recruiting | Q1 2027 2027-02-15 (est.) | Estimated · fresh
Updated 5mo ago
| NCT02972840 |
| Hoffmann-La Roche | A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer) Asset: Giredestrant | Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer | Recruiting | Q1 2027 2027-02-19 (est.) | Estimated · fresh
Updated 3mo ago
| NCT06065748 |
| AstraZeneca | Roll Over StudY for Patients Who Have Completed a Previous Oncology Study With Osimertinib (TAGRISSO) (ROSY-T) Asset: Osimertinib | Cancer | Active Not Recruiting | Q1 2027 2027-02-22 (est.) | Estimated · fresh
Updated 3mo ago
| NCT05629234 |
| Acerta Pharma BV | A Combination of Acalabrutinib With R-CHOP in Subjects With Previously Untreated Non-GCB DLBCL (ACE-LY-312) | Diffuse Large B-Cell Lymphoma | Active Not Recruiting | Q1 2027 2027-02-22 (est.) | Estimated · fresh
Updated 4mo ago
| NCT04529772 |
| Novartis Pharmaceuticals | Study of Alpelisib (BYL719) in Combination With Trastuzumab and Pertuzumab as Maintenance Therapy in Patients With HER2-positive Advanced Breast Cancer With a PIK3CA Mutation | Advanced HER2+Breast Cancer | Active Not Recruiting | Q1 2027 2027-02-26 (est.) | Estimated · fresh
Updated 4mo ago
| NCT04208178 |
| Genmab | Study to Assess the Efficacy of Rina-S Compared to Treatment of Investigator's Choice in Participants With Platinum Resistant Ovarian Cancer Asset: Rina-S | Platinum-resistant Ovarian Cancer | Active Not Recruiting | Q1 2027 2027-02 (est.) | Estimated · fresh
Updated 5mo ago
| NCT06619236 |
| Gilead Sciences | Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice and Pembrolizumab in Patients With Previously Untreated, Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer | Triple Negative Breast Cancer +1 | Active Not Recruiting | Q1 2027 2027-02 (est.) | Estimated · aging
Updated 10mo ago
| NCT05382286 |
| Celltrion | A Study to Compare Effects and Safety of CT-P51 and Keytruda in Patients With Previously Untreated Metastatic Lung Cancer Asset: CT-P51 | Non Squamous Non Small Cell Lung Cancer | Active Not Recruiting | Q1 2027 2027-02 (est.) | Estimated · stale
Updated 15mo ago
| NCT06939595 |
| Hansoh BioMedical R&D Company | HS-20089 for Injection in Patients With Platinum-Resistant Recurrent Epithelial Ovarian Cancer Asset: HS-20089 | Ovarian Cancer | Recruiting | Q1 2027 2027-03-07 (est.) | Estimated · aging
Updated 7mo ago
| NCT06855069 |
| Bristol-Myers Squibb | A Study of Nivolumab Combined With Ipilimumab Versus Nivolumab Alone in Participants With Advanced Kidney Cancer | Renal Cell Carcinoma | Active Not Recruiting | Q1 2027 2027-03-11 (est.) | Estimated · fresh
Updated 6mo ago
| NCT03873402 |
| Regeneron Pharmaceuticals | A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head) Asset: fianlimab | Melanoma | Recruiting | Q1 2027 2027-03-22 (est.) | Estimated · fresh
Updated 5mo ago
| NCT06246916 |
| Shanghai JMT-Bio Inc. | JMT101 in Combination With Osimertinib, Versus Cisplatin-pemetrexed in Participants With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Characterized by Epithermal Growth Factor Receptor (EGFR) Exon 20ins Mutations Asset: JMT101 Injection | Local Advanced or Metastatic NSCLC | Not Yet Recruiting | Q1 2027 2027-03-26 (est.) | Estimated · stale
Updated 27mo ago
| NCT06380348 |
| Jiangsu HengRui Medicine Co., Ltd. | A Phase III Clinical Study of Rezvilutamide in Patients With Metastatic Hormone-Sensitive Prostate Cancer Asset: Rezvilutamide Tablets | Metastatic Hormone-sensitive Prostate Cancer (mHSPC) | Recruiting | Q1 2027 2027-03 (est.) | Estimated · fresh
Updated 6mo ago
| NCT07241416 |
| Novartis Pharmaceuticals | Study of Out of Specification for Tisagenlecleucel Asset: CTL019 | B-cell Acute Lymphoblastic Leukemia +1 | Recruiting | Q1 2027 2027-03-31 (est.) | Estimated · fresh
Updated 3mo ago
| NCT04094311 |
| TuHURA Biosciences, Inc. | Placebo-Controlled Trial of IFx-Hu2.0 Followed By Pembrolizumab In Checkpoint Inhibitor Naïve Participants With Advanced Or Metastatic Merkel Cell Carcinoma Asset: IFx-Hu2.0 | Advanced Or Metastatic Merkel Cell Carcinoma | Recruiting | Q1 2027 2027-03-31 (est.) | Estimated · fresh
Updated 3mo ago
| NCT06947928 |
| Hoffmann-La Roche | A Study of Atezolizumab With or Without Tiragolumab in Participants With Unresectable Esophageal Squamous Cell Carcinoma Whose Cancers Have Not Progressed Following Definitive Concurrent Chemoradiotherapy | Esophageal Squamous Cell Carcinoma | Active Not Recruiting | Q1 2027 2027-03-31 (est.) | Estimated · fresh
Updated 3mo ago
| NCT04543617 |
| Quetzal Therapeutics | Pivotal Open-label Phase 3 Clinical Study of QTX-2101 in Adult Patients With Acute Promyelocytic Leukemia Asset: QTX-2101 + ATRA | Acute Promyelocytic Leukemia (APL) +4 | Recruiting | Q1 2027 2027-03 (est.) | Estimated · fresh
Updated 3mo ago
| NCT07504458 |
| ABX advanced biochemical compounds… | Diagnostic Performance of [18F]PSMA-1007 PET/CT Imaging in Patients With Newly-Diagnosed Prostate Cancer Asset: [18F]PSMA-1007 | Prostate Cancer | Recruiting | Q1 2027 2027-03 (est.) | Estimated · fresh
Updated 3mo ago
| NCT06122584 |
| Suzhou Suncadia Biopharmaceuticals… | A Phase 3 Clinical Study of SHR-A1912 Combined With R-GemOx Versus R-GemOx in Diffuse Large B-cell Lymphoma Asset: SHR-A1912 Injection | Diffuse Large B-cell Lymphoma | Recruiting | Q1 2027 2027-03 (est.) | Estimated · aging
Updated 8mo ago
| NCT06929624 |
| BeOne Medicines | A Study to Investigate the Efficacy of Zanubrutinib Plus Rituximab Compared With Bendamustine Plus Rituximab in Adults With Previously Untreated Mantle Cell Lymphoma Who Are Ineligible for Stem Cell Transplantation | Mantle Cell Lymphoma; Non-Hodgkin Lymphoma | Active Not Recruiting | Q1 2027 2027-03 (est.) | Estimated · aging
Updated 10mo ago
| NCT04002297 |
| Hangzhou Sumgen Biotech Co., Ltd. | A Clinical Study Comparing SG301 Plus Pomalidomide and Dexamethasone to Placebo Plus Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma Patients Asset: SG301 Injection | Relapsed/Refractory Multiple Myeloma | Recruiting | Q1 2027 2027-03-31 (est.) | Estimated · stale
Updated 13mo ago
| NCT06508983 |
| Seattle Project Corporation | A Study of a Patient-Specific Neoantigen Vaccine in Combination With Immune Checkpoint Blockade for Patients With Metastatic Colorectal Cancer Asset: GRT-C901 | Colorectal Neoplasms | Active Not Recruiting | Q1 2027 2027-03 (est.) | Estimated · stale
Updated 14mo ago
| NCT05141721 |
| Pierre Fabre Medicament | Adjuvant Encorafenib and Binimetinib in High-risk Stage II Melanoma With a BRAF Mutation. | Melanoma | Active Not Recruiting | Q1 2027 2027-03-31 (est.) | Estimated · stale
Updated 32mo ago
| NCT05270044 |
| Jiangsu Famous Medical Technology … | Xian-Lian-Jie-Du Optimization Decoction As an Adjuvant Treatment for Prevention of Recurrence of Colon Cancer Asset: XLJDOD compound granule | Colon Cancer | Recruiting | Q2 2027 2027-04-01 (est.) | Estimated · stale
Updated 19mo ago
| NCT05709249 |
| AstraZeneca | Roll Over StudY for Patients Who Have Completed a Previous Oncology Study With Olaparib | Ovarian Cancer +1 | Active Not Recruiting | Q2 2027 2027-04-06 (est.) | Estimated · fresh
Updated 3mo ago
| NCT04421963 |
| Celgene | Efficacy and Safety Study of bb2121 Versus Standard Regimens in Subjects With Relapsed and Refractory Multiple Myeloma (RRMM) Asset: bb2121 | Multiple Myeloma | Completed | Q2 2027 2027-04-08 (est.) | Estimated · stale
Updated 43mo ago
| NCT03651128 |
| Shanghai Henlius Biotech | A Study to Compare the Efficacy, Safety, Immunogenicity, and Pharmacokinetic Profile of HLX17 Vs. Keytruda® in the First-Line Treatment of Advanced Non-squamous Non-small Cell Lung Cancer Asset: HLX17 | Non-Squamous Non-Small Cell Lung Cancer | Not Yet Recruiting | Q2 2027 2027-04-09 (est.) | Estimated · stale
Updated 17mo ago
| NCT06847334 |
| AstraZeneca | A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy Asset: Camizestrant | Breast Cancer, Early Breast Cancer | Recruiting | Q2 2027 2027-04-20 (est.) | Estimated · fresh
Updated 3mo ago
| NCT05774951 |
| LeonaBio | Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation Asset: Lasofoxifene in combination with abemaciclib | Metastatic Breast Cancer | Recruiting | Q2 2027 2027-04 (est.) | Estimated · fresh
Updated 3mo ago
| NCT05696626 |
| Taiho Oncology, Inc. | Futibatinib in Patients Previously Enrolled in an Antecedent Futibatinib as Monotherapy or Combination Therapy. | Advanced/Metastatic Cancer | Enrolling By Invitation | Q2 2027 2027-04 (est.) | Estimated · fresh
Updated 3mo ago
| NCT06506955 |
| Daiichi Sankyo | A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer Asset: Ifinatamab deruxtecan | Small Cell Lung Cancer | Recruiting | Q2 2027 2027-04-30 (est.) | Estimated · fresh
Updated 5mo ago
| NCT06203210 |
| AbbVie | Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer Asset: Mirvetuximab soravtansine plus Bevacizumab | Ovarian Cancer +2 | Active Not Recruiting | Q2 2027 2027-04 (est.) | Estimated · fresh
Updated 5mo ago
| NCT05445778 |
| mAbxience Research S.L. | Study to Compare Pharmacokinetics, Efficacy, Safety, and Immunogenicity of MB11 Versus EU-/US-Opdivo® in Subjects With Previously Untreated Advanced [Unresectable or Metastatic] Melanoma Asset: MB11 (Proposed Nivolumab Biosimilar) | Advanced (Unresectable or Metastatic) Melanoma | Recruiting | Q2 2027 2027-04 (est.) | Estimated · fresh
Updated 6mo ago
| NCT07221734 |
| Shanghai Fosun Pharmaceutical Indu… | FCN-159 Monotherapy Versus Chemotherapy by Investigator's Choice in Pediatric Low-grade Glioma Patients With BRAF Alteration Asset: Luvometinib | Low-grade Glioma +2 | Not Yet Recruiting | Q2 2027 2027-04-30 (est.) | Estimated · stale
Updated 13mo ago
| NCT07004075 |
| Merck Sharp & Dohme LLC | Sacituzumab Tirumotecan (MK-2870) Versus Chemotherapy in Previously Treated Advanced or Metastatic Nonsquamous Non-small Cell Lung Cancer (NSCLC) With EGFR Mutations or Other Genomic Alterations (MK-2870-004) Asset: Sacituzumab tirumotecan | Non-small Cell Lung Cancer (NSCLC) | Active Not Recruiting | Q2 2027 2027-05-10 (est.) | Estimated · fresh
Updated 3mo ago
| NCT06074588 |
| Regeneron Pharmaceuticals | A Trial to Learn How Effective and Safe Odronextamab is Compared to Standard of Care for Adult Participants With Previously Treated Aggressive B-cell Non-Hodgkin Lymphoma Asset: Odronextamab | B-Cell Non-Hodgkin Lymphoma (B-NHL) | Active Not Recruiting | Q2 2027 2027-05-14 (est.) | Estimated · fresh
Updated 3mo ago
| NCT06230224 |
| Akeso | A Phase III Study of Ivonescimab + Chemo With/Without AK117 in Metastatic Pancreatic Cancer Asset: Ivonescimab, AK117, Albumin-bound Paclitaxel, Gemcitabine | Pancreatic Cancer | Recruiting | Q2 2027 2027-05-14 (est.) | Estimated · fresh
Updated 4mo ago
| NCT06953999 |
| Merck Sharp & Dohme LLC | A Study of Nemtabrutinib vs Chemoimmunotherapy for Participants With Previously Untreated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) Without TP53 Aberrations (MK-1026-008, BELLWAVE-008) Asset: Nemtabrutinib | Chronic Lymphocytic Leukemia +1 | Active Not Recruiting | Q2 2027 2027-05-19 (est.) | Estimated · fresh
Updated 4mo ago
| NCT05624554 |
| Merck Sharp & Dohme LLC | Study of Pembrolizumab (MK-3475) Versus Chemotherapy in Mismatch Repair Deficient (dMMR) Advanced or Recurrent Endometrial Carcinoma (MK-3475-C93/KEYNOTE-C93/GOG-3064/ENGOT-en15) | Endometrial Neoplasms | Active Not Recruiting | Q2 2027 2027-05-27 (est.) | Estimated · stale
Updated 20mo ago
| NCT05173987 |
| Sichuan Kelun-Biotech Biopharmaceu… | A Study of SKB264 in Combination With Osimertinib Versus Osimertinib in Patients With Epidermal Growth Factor Receptor (EGFR) Mutations, Locally Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer Asset: SKB264 | Non-Small Cell Lung Cancer | Active Not Recruiting | Q2 2027 2027-05 (est.) | Estimated · aging
Updated 7mo ago
| NCT06670196 |
| Priothera SAS | Mocravimod as Adjunctive and Maintenance Treatment in AML Patients Undergoing Allo-HCT Asset: mocravimod | Adult Acute Myeloid Leukemia | Recruiting | Q2 2027 2027-05 (est.) | Estimated · fresh
Updated 3mo ago
| NCT05429632 |
| Jiangsu HengRui Medicine Co., Ltd. | A Study of SHR-A1811 in Subjects With Ovarian Cancer Asset: SHR-A1811 | Ovarian Cancer | Recruiting | Q2 2027 2027-05 (est.) | Estimated · fresh
Updated 3mo ago
| NCT06828354 |
| Akeso | Ivonescimab in Combination With Docetaxel in Advanced Non-Small Cell Lung Cancer Asset: Ivonescimab, docetaxel | Non-Small Cell Lung Cancer | Recruiting | Q2 2027 2027-05 (est.) | Estimated · fresh
Updated 3mo ago
| NCT06928389 |
| Sichuan Baili Pharmaceutical Co., … | A Study of BL-M07D1 Versus Investigator's Choice of Chemotherapy in Patients With HER2-low Recurrent/Metastatic Breast Cancer Asset: BL-M07D1 | HER2-low Breast Cancer | Recruiting | Q2 2027 2027-05 (est.) | Estimated · fresh
Updated 6mo ago
| NCT06957886 |
| Suzhou Immunofoco Biotechnology Co… | A Phase III Randomized Study in CLDN18.2-positive Unresectable Locally Advanced Gastric Cancer Patients Asset: CAR T cells | Gastric Adenocarcinoma | Recruiting | Q2 2027 2027-05-31 (est.) | Estimated · aging
Updated 9mo ago
| NCT07103668 |
| Qilu Pharmaceutical Co., Ltd. | A Study of MHB088C Injection Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer Asset: MHB088C for Injection | Small Cell Lung Cancer Extensive Stage | Recruiting | Q2 2027 2027-05 (est.) | Estimated · stale
Updated 13mo ago
| NCT06954246 |
| InSightec | Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Mets | Brain Tumor +1 | Recruiting | Q2 2027 2027-06-01 (est.) | Estimated · fresh
Updated 3mo ago
| NCT05317858 |
| Shanghai Henlius Biotech | A Phase Ⅲ Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer Asset: HLX22 | Gastroesophageal-junction Cancer +3 | Recruiting | Q2 2027 2027-06-01 (est.) | Estimated · fresh
Updated 5mo ago
| NCT06532006 |
| Shanghai JMT-Bio Inc. | The Study of JMT101 Combined With Irinotecan as a ≥3rd-Line Treatment in Metastatic Colorectal Cancer Asset: JMT101 | Metastatic Colorectal Cancer (mCRC) | Not Yet Recruiting | Q2 2027 2027-06-01 (est.) | Estimated · aging
Updated 11mo ago
| NCT07134205 |
| Novartis Pharmaceuticals | An Extension Study for Patients Previously Enrolled in Studies With Pelabresib Asset: Pelabresib | Hematologic Malignancy +2 | Recruiting | Q2 2027 2027-06-02 (est.) | Estimated · stale
Updated 13mo ago
| NCT06401356 |
| Shanghai Henlius Biotech | A Study to Compare the Efficacy, Safety, Immunogenicity, and Pharmacokinetic Profile of HLX13 with YERVOY As a First-Line Treatment for Patients with Unresectable Hepatocellular Carcinoma Asset: HLX13 | Hepatocellular Carcinoma (HCC) | Not Yet Recruiting | Q2 2027 2027-06-06 (est.) | Estimated · stale
Updated 17mo ago
| NCT06841185 |
| Merck Sharp & Dohme LLC | A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, vs Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012)-China Extension Study | Carcinoma, Renal Cell | Active Not Recruiting | Q2 2027 2027-06-07 (est.) | Estimated · aging
Updated 8mo ago
| NCT05899049 |
| Bristol-Myers Squibb | ELEMENT-MDS: A Study to Compare the Efficacy and Safety of Luspatercept in Participants With Myelodysplastic Syndrome (MDS) and Anemia Not Receiving Blood Transfusions | Myelodysplastic Syndromes | Active Not Recruiting | Q2 2027 2027-06-25 (est.) | Estimated · fresh
Updated 4mo ago
| NCT05949684 |
| Amgen | A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202) | Non-Small Cell Lung Cancer (NSCLC) | Recruiting | Q2 2027 2027-06-30 (est.) | Estimated · fresh
Updated 3mo ago
| NCT05920356 |
| Gilead Sciences | Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63) Asset: Sacituzumab govitecan-hziy (SG) | Triple Negative Breast Cancer | Recruiting | Q2 2027 2027-06 (est.) | Estimated · fresh
Updated 6mo ago
| NCT05633654 |
| BeiGene | Study of Tislelizumab in Combination With Chemotherapy Compared to Chemotherapy Alone for Participants With Urothelial Carcinoma | Urothelial Carcinoma | Active Not Recruiting | Q2 2027 2027-06-30 (est.) | Estimated · fresh
Updated 3mo ago
| NCT03967977 |
| Sichuan Baili Pharmaceutical Co., … | A Study Comparing BL-B01D1 With Chemotherapy of Physician's Choice in Patients With Recurrent or Metastatic Urothelial Carcinoma(PANKU-Bladder01) Asset: BL-B01D1 | Urothelial Carcinoma | Recruiting | Q2 2027 2027-06 (est.) | Estimated · fresh
Updated 3mo ago
| NCT06857175 |
| Sichuan Baili Pharmaceutical Co., … | A Study Comparing BL-B01D1 With the Investigator's Choice of Chemotherapy in Patients With Platinum-resistant Recurrent Epithelial Ovarian Cancer(PANKU-GYN01) Asset: BL-B01D1 | Epithelial Ovarian Cancer +2 | Recruiting | Q2 2027 2027-06 (est.) | Estimated · fresh
Updated 3mo ago
| NCT06994195 |
| Hoffmann-La Roche | An Extension Study in Participants Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study (IMbrella C) | Neoplasms | Active Not Recruiting | Q2 2027 2027-06-30 (est.) | Estimated · fresh
Updated 3mo ago
| NCT05112965 |
| Immutep S.A.S. | Study of Eftilagimod Alfa (Efti) in Combination With Pembrolizumab and Chemotherapy Versus Placebo in Combination With Pembrolizumab and Chemotherapy in Participants With Metastatic Non-Small Cell Lung Cancer (NSCLC) (TACTI-004) Asset: eftilagimod alfa | Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC) | Active Not Recruiting | Q2 2027 2027-06 (est.) | Estimated · fresh
Updated 4mo ago
| NCT06726265 |
| Pharmacosmos A/S | Effect of Trilaciclib in the Prevention of Myelosupression in Subjects With Limited-stage Small Cell Lung Cancer Asset: Trilaciclib | Limited Stage Small Cell Lung Cancer | Recruiting | Q2 2027 2027-06 (est.) | Estimated · fresh
Updated 4mo ago
| NCT07473128 |
| Day One Biopharmaceuticals, Inc. | DAY101 vs. Standard of Care Chemotherapy in Pediatric Participants With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2) | Low-grade Glioma +2 | Active Not Recruiting | Q2 2027 2027-06 (est.) | Estimated · fresh
Updated 5mo ago
| NCT05566795 |
| AstraZeneca | A Phase III, Randomised Study of Adjuvant Dato-DXd in Combination With Rilvegostomig or Rilvegostomig Monotherapy Versus Standard of Care, Following Complete Tumour Resection, in Participants With Stage I Adenocarcinoma NSCLC Who Are ctDNA-positive or Have High-risk Pathological Features | Non-small Cell Lung Cancer | Active Not Recruiting | Q2 2027 2027-06-30 (est.) | Estimated · fresh
Updated 6mo ago
| NCT06564844 |
| Changchun GeneScience Pharmaceutic… | Nanocrystalline Megestrol Acetate for Cachectic Stage Locally Advanced Hepatocellular Carcinoma Asset: Nanocrystalline Megestrol Acetate | Cachexia +1 | Not Yet Recruiting | Q2 2027 2027-06-30 (est.) | Estimated · fresh
Updated 6mo ago
| NCT07356037 |
| SDK Therapeutics, Inc. | A Trial to Investigate Whether Oral Arsenic Trioxide Is Similar to Intravenous Arsenic Trioxide in Pharmacokinetics, Safety, and Efficacy (LATITUDE/SDKARS-301) Asset: Oral ATO | Acute Promyelocytic Leukemia (APL) +8 | Not Yet Recruiting | Q2 2027 2027-06 (est.) | Estimated · aging
Updated 7mo ago
| NCT07296445 |
| Genfleet Therapeutics (Shanghai) I… | Phase III Study to Compare GFH375 and Chemotherapy in Patients With KRAS G12D-Mutant Metastatic Pancreatic Cancer Asset: GFH375 | Metastatic Pancreatic Cancer | Recruiting | Q2 2027 2027-06 (est.) | Estimated · aging
Updated 7mo ago
| NCT07262567 |
| Sichuan Baili Pharmaceutical Co., … | A Study of BL-M07D1 Versus Investigator's Choice of Chemotherapy in Patients With HER2-positive Locally Advanced or Metastatic Gastric or Gastro-esophageal Junction Adenocarcinoma Asset: BL-M07D1 | Gastric Adenocarcinoma +1 | Recruiting | Q2 2027 2027-06 (est.) | Estimated · aging
Updated 8mo ago
| NCT07152405 |
| Qilu Pharmaceutical Co., Ltd. | A Phase III Study of ESG401 for Unresectable Recurrent or Metastatic Triple-Negative Breast Cancer Asset: ESG401 | Triple-Negative Breast Cancer (TNBC) | Recruiting | Q2 2027 2027-06 (est.) | Estimated · aging
Updated 10mo ago
| NCT06732323 |
| ITM Solucin GmbH | Lutetium 177Lu-Edotreotide Versus Best Standard of Care in Well-differentiated Aggressive Grade-2 and Grade-3 GastroEnteroPancreatic NeuroEndocrine Tumors (GEP-NETs) - COMPOSE Asset: 177Lu-Edotreotide (Peptide Receptor Radionuclide Therapy) PRRT | Neuroendocrine Tumors | Active Not Recruiting | Q2 2027 2027-06 (est.) | Estimated · aging
Updated 10mo ago
| NCT04919226 |
| Changchun GeneScience Pharmaceutic… | Nanocrystalline Megestrol Acetate in Concurrent Chemoradiotherapy for Locally Advanced Non-Small Cell Lung Cancer Asset: Nano-crystalline Megestrol Acetate Oral Suspension | Non-small Cell Lung Cancer | Recruiting | Q2 2027 2027-06-30 (est.) | Estimated · aging
Updated 10mo ago
| NCT07150663 |
| Lepu Biopharma Co., Ltd. | A Study Comparing MRG004A Plus Best Supportive Care Versus Placebo and Best Supportive Care in the Treatment of Patients With Advanced Pancreatic Cancer Asset: MRG004A plus best supportive care | Advanced Pancreatic Cancer | Not Yet Recruiting | Q2 2027 2027-06 (est.) | Estimated · aging
Updated 11mo ago
| NCT07138846 |
| Innovent Biologics (Suzhou) Co. Ltd. | A Multicenter Study of IBI343 Monotherapy Versus Placebo in Subjects With Previously Treated, Claudin (CLDN) 18.2-positive, Pancreatic Cancer(G-HOPE-002) Asset: IBI343 | Pancreatic Cancer | Recruiting | Q2 2027 2027-06-30 (est.) | Estimated · aging
Updated 11mo ago
| NCT07066098 |
| Qilu Pharmaceutical Co., Ltd. | A Phase III Study of ESG401 for Locally Advanced or Metastatic HR+/HER2- Breast Cancer Asset: ESG401 | Metastatic Breast Cancer | Recruiting | Q2 2027 2027-06-30 (est.) | Estimated · stale
Updated 13mo ago
| NCT06383767 |
| Changchun GeneScience Pharmaceutic… | Clinical Study on Nanocrystalline Megestrol Acetate for Appetite Improvement and Weight Gain in Pre-Cachexia and Cachexia Stages Key Terminology Analysis Asset: Nano-crystalline Megestrol Acetate Oral Suspension | Metastatic (Stage IV) Non-squamous Non-small Cell Lung Cancer (Nsq-NSCLC) With Driver Gene Negativity +1 | Not Yet Recruiting | Q2 2027 2027-06-30 (est.) | Estimated · stale
Updated 14mo ago
| NCT06961188 |
| Genmab | A Study to Evaluate Change in Disease Activity of Subcutaneous (SC) Epcoritamab Combined With Intravenous and Oral Rituximab, Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine, and Prednisone (R-CHOP) or R-CHOP in Adult Participants With Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL) | Diffuse Large B-Cell Lymphoma | Active Not Recruiting | Q2 2027 2027-06 (est.) | Estimated · stale
Updated 18mo ago
| NCT05578976 |
| InnoBM Pharmaceuticals Co., Ltd. | A Clinical Trial Assessing the Safety and Efficacy of Biodegradable Magnesium Embolic Microspheres for Primary Hepatocellular Carcinoma | Hepatocellular Carcinoma Non-Resectable | Not Yet Recruiting | Q2 2027 2027-06 (est.) | Estimated · stale
Updated 18mo ago
| NCT06779461 |
| Changchun GeneScience Pharmaceutic… | Nano-crystalline Megestrol Acetate for Adjuvant Treatment in High-risk Head and Neck Squamous Cell Carcinoma After Surgery. Asset: Nano-crystalline Megestrol Acetate Oral Suspension | Head and Neck Squamous Cell Carcinoma; Underwent Surgery Within 6 Weeks and Postoperative Assessment Indicated High-risk Factors | Not Yet Recruiting | Q2 2027 2027-06-30 (est.) | Estimated · stale
Updated 18mo ago
| NCT06772428 |
| Jiangsu HengRui Medicine Co., Ltd. | SHR-A1811 for Subjects With Her2-positive Gastric Cancer and Gastroesophageal Junction Adenocarcinoma After Progression on or After First-line Anti-HER2 Therapy-containing Regimen Asset: SHR-A1811 | HER2-positive Advanced Gastric Cancer or Gastroesophageal Junction Adenocarcinoma | Recruiting | Q2 2027 2027-06-30 (est.) | Estimated · stale
Updated 30mo ago
| NCT06123494 |
| Shanghai Yizhong Pharmaceutical Co… | Polymeric Micellar Paclitaxel for Metastatic Pancreatic Cancer | Pancreatic Cancer Metastatic | Recruiting | Q3 2027 2027-07-01 (est.) | Estimated · fresh
Updated 5mo ago
| NCT06752811 |
| Shijiazhuang Yiling Pharmaceutical… | A Study of XY0206 Versus Salvage Chemotherapy In Patients With Relapsed or Refractory AML With FLT3-ITD-Mutation (ALIVE) Asset: XY0206 | Acute Myeloid Leukemia With FLT3/ITD Mutation | Not Yet Recruiting | Q3 2027 2027-07-01 (est.) | Estimated · stale
Updated 38mo ago
| NCT05876832 |
| Amgen | Study Comparing Tarlatamab and Durvalumab Versus Durvalumab Alone in First-Line Extensive-Stage Small-Cell Lung Cancer (ES-SCLC) Following Platinum, Etoposide and Durvalumab | Extensive-Stage Small-Cell Lung Cancer +1 | Active Not Recruiting | Q3 2027 2027-07-05 (est.) | Estimated · aging
Updated 7mo ago
| NCT06211036 |
| Merck Sharp & Dohme LLC | A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010) Asset: Sacituzumab tirumotecan | Breast Neoplasms | Recruiting | Q3 2027 2027-07-11 (est.) | Estimated · fresh
Updated 4mo ago
| NCT06312176 |
| AstraZeneca | A Study of Acalabrutinib Plus Venetoclax Versus Venetoclax Plus Obinutuzumab in Previously Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma | Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma | Active Not Recruiting | Q3 2027 2027-07-15 (est.) | Estimated · fresh
Updated 5mo ago
| NCT05057494 |