Pain Drugs
511 FDA-approved drugs
TheraRadar tracks 511 FDA-approved pain drugs from 222 companies across 10 drug classes, led by Johnson & Johnson, with 784 active clinical trials in the pipeline. Explore recent approvals, top companies, active trials by indication, and drug classes for Pain.
Pain Approvals by Year
8
'15
4
'16
5
'17
10
'18
3
'19
5
'20
5
'21
'22
3
'23
3
'24
5
'25
1
'26
Recent Pain Drug Approvals
TAPENTADOL HYDROCHLORIDE
TAPENTADOL HYDROCHLORIDE
the management of acute pain severe enough to require an opioid analgesic and for which alternative ...
2026-01-26
NOVITIUM PHARMA
BONDLIDO
LIDOCAINE
BONDLIDO (lidocaine topical system 10%) is indicated in adults for relief of pain associated with po...
2025-09-24
MEDRX USA
XIFYRM
MELOXICAM
use in adults for the management of moderate-to-severe pain, alone or in combination with non-NSAID ...
2025-06-05
AZURITY
COX-1COX-2
PHENYLEPHRINE HYDROCHLORIDE IN 0.9% SODIUM CHLORIDE
PHENYLEPHRINE HYDROCHLORIDE
increasing blood pressure in adults with clinically important hypotension resulting primarily from v...
2025-05-30
Dr. Reddy's
QAMZOVA
MELOXICAM
use in adults for the management of moderate-to-severe pain, alone or in combination with non-NSAID ...
2025-04-22
NANJING DELOVA
COX-1COX-2
JOURNAVX
SUZETRIGINE
moderate to severe acute pain, including postoperative pain, in adults...
2025-01-30
Vertex Pharmaceuticals
NaV1.8SCN10A
BUPIVACAINE LIPOSOME
BUPIVACAINE
2024-07-01
HENGRUI PHARMA
REZENOPY
NALOXONE HYDROCHLORIDE
the emergency treatment of known or suspected opioid overdose, as manifested by respiratory and/or c...
2024-04-19
SCIENTURE
opioid receptor
BYQLOVI
CLOBETASOL PROPIONATE
post-operative inflammation and pain following ocular surgery...
2024-03-04
HARROW EYE
Phospholipase A2
COMBOGESIC IV
ACETAMINOPHEN
short-term use of five days or less...
2023-10-17
Hikma
COX-1COX-2
COMBOGESIC
ACETAMINOPHEN
COMBOGESIC is indicated in adults for the short-term management of mild to moderate acute pain...
2023-03-01
AFT PHARMS US
COX-1COX-2
ACETAMINOPHEN AND IBUPROFEN
ACETAMINOPHEN
2023-02-28
STRIDES PHARMA
SEGLENTIS
CELECOXIB
2021-10-15
KOWA PHARMS
DIFLUPREDNATE
DIFLUPREDNATE
inflammation and pain associated with ocular surgery...
2021-08-09
Dr. Reddy's
Phospholipase A2
IBUPROFEN AND FAMOTIDINE
FAMOTIDINE
the relief of signs and symptoms of rheumatoid arthritis and osteoarthritis and to decrease the risk...
2021-08-03
Aurobindo Pharma
HYDROCODONE BITARTRATE AND ASPIRIN
ASPIRIN
the management of pain severe enough to require an opioid analgesic and for which alternative treatm...
2021-05-28
LGM PHARMA
POSIMIR
BUPIVACAINE
2021-02-01
INNOCOLL
QDOLO
TRAMADOL HYDROCHLORIDE
2020-09-01
ROSEMONT
OLINVYK
OLICERIDINE
2020-08-07
TREVENA
ADVIL DUAL ACTION WITH ACETAMINOPHEN
ACETAMINOPHEN
2020-02-28
HALEON US HOLDINGS
Showing the 20 most recent of 511 pain drugs. View all 511 →
Top Pain Companies
Pain Active Trials by Indication
784 active trials — the forward pipeline, not just approvals.
All competitive landscapes →Pain Drug Classes
Nonsteroidal Anti-inflammatory Drug 14
Barbiturate 7
Amide Local Anesthetic 6
Opioid Agonist 6
Partial Opioid Agonist 2
Non-Standardized Food Allergenic Extract 2
alpha-1 Adrenergic Agonist 1
Sodium Channel Blocker 1
Histamine-2 Receptor Antagonist 1
Nitrate Vasodilator 1
Pain at a Glance
- Total Drugs
- 511
- Companies
- 222
- Drug Classes
- 10
- Active Trials
- 784
- Latest Approval
- 2026-01-26