ESMOLOL HYDROCHLORIDE IN PLASTIC CONTAINER (esmolol hydrochloride)
Esmolol hydrochloride is a short-acting medication used for the rapid control of heart rate in patients experiencing atrial fibrillation or atrial flutter. It also helps patients with noncompensatory sinus tachycardia when a physician determines the heart rate needs specific intervention. Additionally, it treats high blood pressure and rapid heart rate that can occur during or immediately after surgery, such as during intubation or while waking up from anesthesia.
How ESMOLOL HYDROCHLORIDE IN PLASTIC CONTAINER Works
This drug works by blocking beta 1 receptors located primarily in the heart muscle. By inhibiting these receptors, it slows the heart rate and lowers blood pressure with a very fast onset and a short duration of action. While it mainly targets the heart, higher doses can also affect receptors in the lungs and blood vessels.
Details
- Status
- Prescription
- First Approved
- 2016-04-07
- Patent Cliff
- 2033
- Routes
- INTRAVENOUS
- Dosage Forms
- SOLUTION
ESMOLOL HYDROCHLORIDE IN PLASTIC CONTAINER Approval History
What ESMOLOL HYDROCHLORIDE IN PLASTIC CONTAINER Treats
6 indicationsESMOLOL HYDROCHLORIDE IN PLASTIC CONTAINER is approved for 6 conditions since its original approval in 2016. These indications span multiple therapeutic areas including oncology, immunology, and more.
- Supraventricular Tachycardia
- Atrial Fibrillation
- Atrial Flutter
- Sinus Tachycardia
- Tachycardia
- Hypertension
ESMOLOL HYDROCHLORIDE IN PLASTIC CONTAINER Competitive Set
ProThree rings of competition based on shared molecular targets and treated indications.
Direct competitors
Same target(s) AND same indication — head-to-head.
Indication competitors
Same indication, different mechanism — what else might this patient receive?
Filters applied: drops same-active-ingredient (505(b)(2) reformulations), route-mismatch (topical vs systemic), and cross-therapeutic-area matches in same-indication rings.
What's emerging in ESMOLOL HYDROCHLORIDE IN PLASTIC CONTAINER's indications
See all emerging drugs →Phase 3 candidates targeting molecules with no FDA-approved drug, in indications ESMOLOL HYDROCHLORIDE IN PLASTIC CONTAINER treats. First-in-class if their pivotal trials read out positive.
Drugs Similar to ESMOLOL HYDROCHLORIDE IN PLASTIC CONTAINER
3 of 20FDA-approved drugs for similar conditions. Compare mechanisms and indications to understand treatment alternatives.
Clinical Trial Registry
5 trials| Trial | Sponsor ID | Phase | Status | Title |
|---|---|---|---|---|
| NCT06291363 ESMONOL | 2024-3612 | Ph 4 | recruiting | Impact of Administration of Esmolol on Nociception Level-guided Control of Nociception. |
| NCT01113515 results posted | Novalead-Galnobax-0210 | Ph 1, Ph 2 | completed | Clinical Investigation of Galnobax® for the Treatment of Diabetic Foot Ulcers |
| NCT03998436 results posted | NG-A16 | Ph 3 | completed | Phase 3 Study to Evaluate the Safety and Efficacy of Galnobax® in Treating Diabetic Foot Ulcers |
| NCT02967029 | IstanbulUn | Ph 4 | completed | Effect of Controlled Hypotension on Cerebral Oxygen Saturation |
| NCT01652898 | AOP LDLA202.101 | Ph 1 | completed | A Pharmacokinetic, Pharmacodynamic, Safety Study With AOP LDLA202, ONO LDL50 and Esmolol in Healthy Volunteers |
Active Pipeline
Ongoing clinical trials by development phase
Key Completed Trials
Completed studies with published results, ranked by significance
Trial Timeline
Full development history with FDA approval milestones
Understanding FDA Approval Types
| Count | Type | What it means |
|---|---|---|
| - | ORIG | Original approval - drug first enters market |
| - | SUPPL - Efficacy | New indication (new disease/condition approved) |
| - | SUPPL - Labeling | Label text changes (warnings, dosing updates) |
| - | SUPPL - Manufacturing | Production changes (new facility) |
| - | SUPPL - Chemistry | Formulation changes (new dosage strength) |
Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.
ESMOLOL HYDROCHLORIDE IN PLASTIC CONTAINER FDA Label Details
Indications & Usage
FDA Label (PDF)ESMOLOL HYDROCHLORIDE IN PLASTIC CONTAINER is indicated for the treatment of Supraventricular Tachycardia; Atrial Fibrillation; Atrial Flutter; Sinus Tachycardia; Tachycardia; Hypertension.
ESMOLOL HYDROCHLORIDE IN PLASTIC CONTAINER Patents & Exclusivity
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Deep insights for ESMOLOL HYDROCHLORIDE IN PLASTIC CONTAINER
Revenue Insights
- • Quarterly revenue tracking
- • Historical trend analysis
Patent Timeline
- • Cliff: 2033
- • 4 active patents
Trial Analysis
- • Clinical trial tracking
- • Development stage analysis
Competitive Landscape
- • 20 similar drugs
- • Same target/indication analysis
Full approval history • All patents • Revenue trends • Competitor analysis
Data Sources
Data sourced from official FDA and NIH databases. Click links to verify on original sources.