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Data updated: May 26, 2026

OMNIPRED (prednisolone acetate)

Ophthalmology Approved 1973-07-10

OMNIPRED is indicated for the treatment of Inflammation of the Conjunctiva; Inflammation of the Cornea.

Source: FDA Label • Novartis
2
Indications
--
Phase 3 Trials
52
Years on Market

Details

Status
Prescription
First Approved
1973-07-10
Routes
OPHTHALMIC
Dosage Forms
SUSPENSION/DROPS

Companies

Active Ingredient: PREDNISOLONE ACETATE

OMNIPRED Approval History

1974
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Original
New Indication
New Form
Label Update
35 FDA actions from 1973 to 2024 · 1 indication expansions
Dec 2024 SUPPL
Label · Labeling
Mar 2022 SUPPL
Label · Labeling
Oct 2007 SUPPL
Label · Labeling

What OMNIPRED Treats

2 indications

OMNIPRED is approved for 2 conditions since its original approval in 1973. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Inflammation of the Conjunctiva
  • Inflammation of the Cornea
Source: FDA Label

OMNIPRED Competitive Set

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Filters applied: drops same-active-ingredient (505(b)(2) reformulations), route-mismatch (topical vs systemic), and cross-therapeutic-area matches in same-indication rings.

Drugs Similar to OMNIPRED

3 of 4

FDA-approved drugs for similar conditions. Compare mechanisms and indications to understand treatment alternatives.

FLAREX
FLUOROMETHOLONE ACETATE
2 shared
HARROW EYE
Shared indications:
Inflammation of the ConjunctivaInflammation of the Cornea
FLUOROMETHOLONE
FLUOROMETHOLONE
2 shared
DIFGEN PHARMS
Shared indications:
Inflammation of the conjunctivaInflammation of the cornea
PRED FORTE
PREDNISOLONE ACETATE
2 shared
AbbVie
Shared indications:
Inflammation of the ConjunctivaInflammation of the Cornea
📋

Clinical Trial Registry

13 trials
Trial Sponsor ID Phase Status Title
NCT04351737 PERSIST PERSIST Study Ph 4 completed Dextenza for Post-operative Treatment of Pterygium
NCT06679153 VVN461-CCS-201 Ph 2 completed A Phase 2 Study of VVN461 Ophthalmic Solution for Noninfectious Anterior Uveitis
NCT04168112 results posted LINK1 Ph 4 completed Intracanalicular Dexamethasone Insert for Post-Corneal Cross-Linking Inflammation and Pain- The LINK Study
NCT04464629 The FINNEN Study Ph 4 terminated Assessing the Efficacy and Safety of DEXTENZA in Pseudo Phakic Patients Undergoing Gas Bubble Repair and Laser Following Retinal Detachment
NCT04563299 DETeR DETeR Ph 4 terminated Effect on Pain and Inflammation With DEXTENZA Treatment in Patients Undergoing Intravitreal Anti-VEGF Injections
NCT01939691 MEND 18-24978 Ph 4 terminated Macular Edema Nepafenac vs. Difluprednate Uveitis Trial
NCT04273282 1909 D3 EyePoint Ph 4 completed A Prospective Clinical Study Evaluating Dexycu vs Prednisolone Acetate 1%
NCT03596723 results posted KPI-121-C-010 Ph 3 terminated KPI-121 1% Versus Prednisolone for the Treatment of Inflammation Following Cataract Surgery in Children
NCT01853072 results posted C-12-067 Ph 3 completed Nepafenac Once Daily for Macular Edema - Study 1
NCT01872611 results posted C-12-071 2013-001874-12 Ph 3 completed Nepafenac Once Daily for Macular Edema - Study 2
NCT01482897 Hiatus BRD 11/4-M Ph 3 terminated Efficacy of corticoïd Infiltration Via Sacro-coccygien Hiatus in Discal Sciatica
NCT01448213 results posted 2011-0329 Ph 2 completed Comparison of Two Steroid Regimens to Prevent Transplant Rejection After Corneal Transplant (DMEK)
NCT00758199 2008-0036 Ph 4 completed Determination of Optimum Duration of Treatment With Bromfenac (Xibrom) Eyedrops Following Cataract Surgery
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Active Pipeline

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Ongoing clinical trials by development phase

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Key Completed Trials

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Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

OMNIPRED FDA Label Details

Indications & Usage

FDA Label (PDF)

OMNIPRED is indicated for the treatment of Inflammation of the Conjunctiva; Inflammation of the Cornea.

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.