TheraRadar

Diabetes

Metabolic 16 original drugs
16
Novel Drugs
16
Reformulations
0
Active Trials
6
Drug Targets

Phase 3 Readouts Pro

11 active Phase 3 trials with confidence-graded completion dates.

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Q2 2026
BERLIM 25/20 ASSOCIATION
EMS
Estimated · fresh NCT04602754
Q3 2026
PIEMONTE
EMS
Estimated · fresh NCT05028140
Q3 2026
GZR4
Gan & Lee Pharmaceuticals.
Estimated · fresh NCT06767735
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Anchored on CT.gov primary completion date. Topline announcements typically precede this by 3–9 months. Confidence labels combine date type (ACTUAL/ESTIMATED) with last-update freshness.

Treatments by Mechanism

Top 12 mechanisms across 180 industry trials with a known mechanism of action.

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Sodium-Glucose Cotransporter 2 Inhibitor
6 trials 1 active 2 sponsors
GLP-1 Receptor Agonist
86 trials 3 sponsors
Insulin Analog
68 trials 7 sponsors
SGLT2
6 trials 1 sponsor
Dipeptidyl Peptidase 4 Inhibitor
6 trials 3 sponsors
DPP-4
2 trials 1 sponsor
Corticosteroid
1 trials 1 sponsor
amylases/lipases/proteases
1 trials 1 sponsor
Glucose-dependent Insulinotropic Polypeptide Receptor Agonist
1 trials 1 sponsor
PCSK9 Inhibitor
1 trials 1 sponsor
Vascular Endothelial Growth Factor Inhibitor
1 trials 1 sponsor
Cytochrome a3/Hemoglobin
1 trials 1 sponsor

MoA derived from FDA pharmClassEpc when intervention matches an approved drug. Codenamed clinical-stage assets without an approved counterpart show "—" and aren't grouped here — they're still in the phase tables below.

Clinical Pipeline by Phase

818 industry-sponsored trials across 206 sponsors

Precision Medicine Biomarkers

All biomarkers →

Biomarkers used for patient selection in Diabetes

Reformulations (16 drugs) Click to expand
Generic Drugs (4 ANDA approved) Click to expand

Generic drugs contain the same active ingredient as the brand-name drug and are approved via ANDA (Abbreviated New Drug Application).

Related Indications

Other Metabolic indications

Drug Categories:

  • Novel Drugs: NDA Type 1/2 (new molecular entity) or original BLA
  • Reformulations: NDA Type 3/5 (new dosage form of existing molecule)
  • Biosimilars: BLA-approved biologics highly similar to reference products
  • Generics: ANDA-approved copies of small molecule drugs

View data sources and methodology