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Multiple Myeloma

Oncology 18 original drugs
18
Novel Drugs
14
Reformulations
666
Active Trials
17
Drug Targets

Phase 3 Readouts Pro

12 active Phase 3 trials with confidence-graded completion dates.

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Q3 2026
Mezigdomide
Bristol-Myers Squibb
Estimated · fresh NCT05552976
Q3 2026
Elranatamab
Pfizer
Estimated · fresh NCT06152575
Q3 2026
Pomalidomide
AbbVie
Estimated · aging NCT03539744
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Anchored on CT.gov primary completion date. Topline announcements typically precede this by 3–9 months. Confidence labels combine date type (ACTUAL/ESTIMATED) with last-update freshness.

Treatments by Mechanism

Top 12 mechanisms across 130 industry trials with a known mechanism of action.

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BCMA/CD3
10 trials 8 active 2 sponsors
CD38-directed Cytolytic Antibody
19 trials 5 active 5 sponsors
Nuclear Export Inhibitor
8 trials 4 active 3 sponsors
Proteasome Inhibitor
26 trials 2 active 10 sponsors
Thalidomide Analog
25 trials 2 active 5 sponsors
Corticosteroid
9 trials 2 active 6 sponsors
BCL-2 Inhibitor
7 trials 2 active 2 sponsors
SLAMF7-directed Immunostimulatory Antibody
8 trials 2 sponsors
Programmed Death Receptor-1 Blocking Antibody
7 trials 2 sponsors
Histone Deacetylase Inhibitor
4 trials 1 sponsor
Kinase Inhibitor
4 trials 3 sponsors
DNA
3 trials 3 sponsors

MoA derived from FDA pharmClassEpc when intervention matches an approved drug. Codenamed clinical-stage assets without an approved counterpart show "—" and aren't grouped here — they're still in the phase tables below.

Clinical Pipeline by Phase

713 industry-sponsored trials across 235 sponsors

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Reformulations (14 drugs) Click to expand
Generic Drugs (6 ANDA approved) Click to expand

Generic drugs contain the same active ingredient as the brand-name drug and are approved via ANDA (Abbreviated New Drug Application).

Related Indications

Other Oncology indications

Drug Categories:

  • Novel Drugs: NDA Type 1/2 (new molecular entity) or original BLA
  • Reformulations: NDA Type 3/5 (new dosage form of existing molecule)
  • Biosimilars: BLA-approved biologics highly similar to reference products
  • Generics: ANDA-approved copies of small molecule drugs

View data sources and methodology